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David Bradway

Research Scientist, Senior
Biomedical Engineering
Room 1427, Fitzpatrick CIEMAS, 101 Science Dr., Box 90281, Durham, NC 27708-0281
100 Science Drive, Durham, NC 27708
Office hours Hudson Annex 259  

Scholarly Works - Journal articles


In Vivo Demonstration of a Real-Time Temporal SNR Acoustic Output Adjustment Method.

Journal article IEEE Trans Ultrason Ferroelectr Freq Control · August 2024 This work proposes a novel method of temporal signal-to-noise ratio (SNR)-guided adaptive acoustic output adjustment and demonstrates this approach during in vivo fetal imaging. Acoustic output adjustment is currently the responsibility of sonographers, bu ... Full text Link to item Cite

Evaluation of Myocardial Stiffness in Cardiac Amyloidosis Using Acoustic Radiation Force Impulse and Natural Shear Wave Imaging.

Journal article Ultrasound Med Biol · August 2023 OBJECTIVE: Increased myocardial stiffness (MS) is an important hallmark of cardiac amyloidosis (CA) caused by myocardial amyloid deposition. Standard echocardiography metrics assess MS indirectly via downstream effects of cardiac stiffening. The ultrasound ... Full text Link to item Cite

Spatial Coherence Adaptive Clutter Filtering in Color Flow Imaging-Part I: Simulation Studies.

Journal article IEEE open journal of ultrasonics, ferroelectrics, and frequency control · January 2022 The appropriate selection of a clutter filter is critical for ensuring the accuracy of velocity estimates in ultrasound color flow imaging. Given the complex spatio-temporal dynamics of flow signal and clutter, however, the manual selection of filters can ... Full text Cite

Spatial Coherence Adaptive Clutter Filtering in Color Flow Imaging-Part II: Phantom and In Vivo Experiments.

Journal article IEEE open journal of ultrasonics, ferroelectrics, and frequency control · January 2022 Conventional color flow processing is associated with a high degree of operator dependence, often requiring the careful tuning of clutter filters and priority encoding to optimize the display and accuracy of color flow images. In a companion paper, we intr ... Full text Cite

An Automated ALARA Method for Ultrasound: An Obstetric Ultrasound Feasibility Study.

Journal article J Ultrasound Med · December 2, 2020 OBJECTIVES: Ultrasound users are advised to observe the ALARA (as low as reasonably achievable) principle, but studies have shown that most do not monitor acoustic output metrics. We developed an adaptive ultrasound method that could suggest acoustic outpu ... Full text Link to item Cite

Clinical Utility of Fetal Short-Lag Spatial Coherence Imaging.

Journal article Ultrasound Med Biol · April 2018 In this study, we evaluate the clinical utility of fetal short-lag spatial coherence (SLSC) imaging. Previous work has documented significant improvements in image quality with fetal SLSC imaging as quantified by measurements of contrast and contrast-to-no ... Full text Link to item Cite

Feasibility of Swept Synthetic Aperture Ultrasound Imaging.

Journal article IEEE transactions on medical imaging · July 2016 Ultrasound image quality is often inherently limited by the physical dimensions of the imaging transducer. We hypothesize that, by collecting synthetic aperture data sets over a range of aperture positions while precisely tracking the position and orientat ... Full text Open Access Cite

Safety Assessment of Advanced Imaging Sequences I: Measurements.

Journal article IEEE transactions on ultrasonics, ferroelectrics, and frequency control · January 2016 A method for rapid measurement of intensities (I(spta)), mechanical index (MI), and probe surface temperature for any ultrasound scanning sequence is presented. It uses the scanner's sampling capability to give an accurate measurement of the whole imaging ... Full text Cite

Contrast in intracardiac acoustic radiation force impulse images of radiofrequency ablation lesions.

Journal article Ultrason Imaging · April 2014 We have previously shown that intracardiac acoustic radiation force impulse (ARFI) imaging visualizes tissue stiffness changes caused by radiofrequency ablation (RFA). The objectives of this in vivo study were to (1) quantify measured ARFI-induced displace ... Full text Open Access Link to item Cite

Acoustic radiation force impulse imaging (ARFI) on an IVUS circular array.

Journal article Ultrasonic imaging · April 2014 Our long-term goal is the detection and characterization of vulnerable plaque in the coronary arteries of the heart using intravascular ultrasound (IVUS) catheters. Vulnerable plaque, characterized by a thin fibrous cap and a soft, lipid-rich necrotic core ... Full text Open Access Cite

Intracardiac acoustic radiation force impulse (ARFI) and shear wave imaging in pigs with focal infarctions.

Journal article IEEE transactions on ultrasonics, ferroelectrics, and frequency control · August 2013 Four pigs, three with focal infarctions in the apical intraventricular septum (IVS) and/or left ventricular free wall (LVFW), were imaged with an intracardiac echocardiography (ICE) transducer. Custom beam sequences were used to excite the myocardium with ... Full text Open Access Cite

Intracardiac acoustic radiation force impulse imaging: a novel imaging method for intraprocedural evaluation of radiofrequency ablation lesions.

Journal article Heart Rhythm · November 2012 BACKGROUND: Arrhythmia recurrence after cardiac radiofrequency ablation (RFA) for atrial fibrillation has been linked to conduction through discontinuous lesion lines. Intraprocedural visualization and corrective ablation of lesion line discontinuities cou ... Full text Open Access Link to item Cite

Acoustic radiation force-based elasticity imaging methods.

Journal article Interface focus · August 2011 Conventional diagnostic ultrasound images portray differences in the acoustic properties of soft tissues, whereas ultrasound-based elasticity images portray differences in the elastic properties of soft tissues (i.e. stiffness, viscosity). The benefit of e ... Full text Cite

Near real time evaluation of cardiac radiofrequency ablation lesions with intracardiac echocardiography based acoustic radiation force impulse imaging.

Journal article The Journal of the Acoustical Society of America · April 1, 2011 [Cardiac radiofrequency (rf) ablation is used to treat cardiac arrhythmias. Multiple rf lesions are created to form lines of electrical block to disrupt arrhythmic wavefronts. However, image based lesion evaluation is not performed and clinicians r ... Full text Cite

Intracardiac measurements of elasticity using Acoustic Radiation ForceImpulse (ARFI) methods: Temporal and spatial stability of shear wave velocimetry

Journal article Proceedings IEEE Ultrasonics Symposium · December 1, 2010 Acoustic Radiation Force Impulse (ARFI) methods have been validated formeasuring tissue elastic properties, with shear wave velocimetry emerging as aquantitative way to measure stiffness. Using ultrasound to interrogate cardiacelasticity holds promise for ... Full text Cite

In vivo guidance and assessment of liver radio-frequency ablation with acoustic radiation force elastography.

Journal article Ultrasound Med Biol · October 2008 The initial results from clinical trials investigating the utility of acoustic radiation force impulse (ARFI) imaging for use with radio-frequency ablation (RFA) procedures in the liver are presented. To date, data have been collected from 6 RFA procedures ... Full text Open Access Link to item Cite

Impulsive acoustic radiation force: imaging approaches and clinical applications

Journal article The Journal of the Acoustical Society of America · May 1, 2008 Focused acoustic radiation force can be used to locally mechanically excite tissue, and the tissue response can be monitored with conventional ultrasonic displacement estimation methods. Many groups are currently exploring the potential for radiati ... Full text Cite

In vivo visualization of abdominal malignancies with acoustic radiation force elastography.

Journal article Phys Med Biol · January 7, 2008 The utility of acoustic radiation force impulse (ARFI) imaging for real-time visualization of abdominal malignancies was investigated. Nine patients presenting with suspicious masses in the liver (n = 7) or kidney (n = 2) underwent combined sonography/ARFI ... Full text Open Access Link to item Cite