Current Duke Appointments & Affiliations
Lindquist McNeill Presidential Distinguished Chair
·
2024 - Present
Medicine, Endocrinology, Metabolism, and Nutrition,
Medicine
Professor of Medicine
·
2015 - Present
Medicine, Endocrinology, Metabolism, and Nutrition,
Medicine
Chief, Division of Endocrinology and Metabolism
·
2014 - Present
Medicine, Endocrinology, Metabolism, and Nutrition,
Medicine
Member of Duke Molecular Physiology Institute
·
2014 - Present
Duke Molecular Physiology Institute,
Institutes and Centers
Recent Scholarly Works
Leveraging Real-World Evidence to Inform Regulatory, Clinical, and Coverage Decisions Related to Glucagon-like Peptide-1-Based Therapies: Synopsis of a National Institute of Diabetes and Digestive and Kidney Diseases Workshop.
Journal article Ann Intern Med · September 2026 Glucagon-like peptide-1 receptor agonists (GLP-1RAs) have transformed obesity and diabetes management, with rapidly expanding indications and use among U.S. adults. Despite their promise, key questions remain about optimal treatment pathways, long-term saf ... Full text Link to item CiteGlucagon promotes net hepatic glycogen repletion following meal ingestion.
Journal article JCI Insight · April 22, 2026 Insulin and glucagon are described as having opposing actions on hepatic glycogen metabolism. However, here we showed that their coordinated action promoted glycogen turnover and meal glucose storage. In mice, pharmacological doses of insulin or glucagon f ... Full text Link to item CiteCardiovascular Outcomes with Tirzepatide in Type 2 Diabetes. Reply.
Journal article N Engl J Med · April 16, 2026 Full text Link to item CiteRecent Grants
Establishing Memory in Adipose Tissue Influences Future Metabolic Outcomes in Obesity
ResearchCollaborator · Awarded by National Institutes of Health · 2026 - 2030Metabolic Actions of Glucagon
ResearchCo-Principal Investigator · Awarded by National Institute of Diabetes and Digestive and Kidney Diseases · 2025 - 2030A gut sense for dietary lysine
ResearchCollaborator · Awarded by National Institutes of Health · 2026 - 2030View All Grants
Education
University of Wisconsin, Madison ·
1983
M.D.