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David A D'Alessio

Lindquist Presidential Distinguished Chair
Medicine, Endocrinology, Metabolism, and Nutrition
DUMC Box 104775, Durham, NC 27710
300 North Duke Street, Durham, NC 27701

Current Appointments & Affiliations


Lindquist Presidential Distinguished Chair · 2024 - Present Medicine, Endocrinology, Metabolism, and Nutrition, Medicine
Professor of Medicine · 2015 - Present Medicine, Endocrinology, Metabolism, and Nutrition, Medicine
Chief, Division of Endocrinology and Metabolism · 2014 - Present Medicine, Endocrinology, Metabolism, and Nutrition, Medicine
Member of Duke Molecular Physiology Institute · 2014 - Present Duke Molecular Physiology Institute, Institutes and Centers

In the News


Published May 18, 2022
University Awards 24 New Distinguished Professorships

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Recent Publications


Development of the Insulin Radioimmunoassay, the Watershed Moment in Diabetes Research: Revisiting 1960 Diabetes Classics by Berson and Yalow.

Journal Article Diabetes · March 1, 2025 The discovery and development of the radioimmunoassay (RIA) for insulin by Berson and Yalow fundamentally changed biomedical science. The story of this accomplishment began with the pairing of brilliant scientists with complementary expertise who identifie ... Full text Link to item Cite

Glucose-dependent insulinotropic polypeptide (GIP).

Journal Article Mol Metab · February 28, 2025 BACKGROUND: Glucose-dependent insulinotropic polypeptide (GIP) was the first incretin identified and plays an essential role in the maintenance of glucose tolerance in healthy humans. Until recently GIP had not been developed as a therapeutic and thus has ... Full text Link to item Cite
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Recent Grants


Endocrinology and Metabolism Training Program

Inst. Training Prgm or CMEPrincipal Investigator · Awarded by National Institutes of Health · 2024 - 2029

Alpha- to Beta-Cell Communication in Health and Disease

ResearchCo-Principal Investigator · Awarded by National Institutes of Health · 2024 - 2029

Gut epithelial control of nutrient reward

ResearchCo-Mentor · Awarded by National Institute of Diabetes and Digestive and Kidney Diseases · 2024 - 2028

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Education, Training & Certifications


University of Wisconsin, Madison · 1983 M.D.