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David M Epstein

Associate Consulting Professor in the Department of Medicine
Medicine, Medical Oncology
56 Pine Street, Belmont, MA 02478

Current Appointments & Affiliations


Associate Consulting Professor in the Department of Medicine · 2015 - Present Medicine, Medical Oncology, Medicine

Recent Publications


A tumor-associated splice-isoform of MAP2K7 drives dedifferentiation in MBNL1-low cancers via JNK activation.

Journal Article Proc Natl Acad Sci U S A · July 14, 2020 Master splicing regulator MBNL1 shapes large transcriptomic changes that drive cellular differentiation during development. Here we demonstrate that MBNL1 is a suppressor of tumor dedifferentiation. We surveyed MBNL1 expression in matched tumor/normal pair ... Full text Link to item Cite
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Education, Training & Certifications


Brandeis University · 1992 Ph.D.