David M Epstein

Associate Consulting Professor in the Department of Medicine

Medicine, Medical Oncology

david.epstein@duke-nus.edu.sg

56 Pine Street, Belmont, MA 02478

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Selected Publications

A tumor-associated splice-isoform of MAP2K7 drives dedifferentiation in MBNL1-low cancers via JNK activation.

Journal Article Proc Natl Acad Sci U S A · July 14, 2020 Master splicing regulator MBNL1 shapes large transcriptomic changes that drive cellular differentiation during development. Here we demonstrate that MBNL1 is a suppressor of tumor dedifferentiation. We surveyed MBNL1 expression in matched tumor/normal pair ... Full text Link to item Cite