David MacAlpine

Professor of Pharmacology and Cancer Biology

Pharmacology & Cancer Biology

david.macalpine@duke.edu

Duke Box 3813, Durham, NC 27710

LSRC C333, Durham, NC 27710

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At a Glance

Credentials
1. Education

Academic Experience
1. Current Duke Appointments & Affiliations
2. Previous Duke Appointments & Affiliations

Global Scholarship

Keywords

Research
1. Selected Grants

Scholarly Works

Teaching & Mentoring
1. Recent Courses

Recognition

Professional Activities

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Scholarly Works - Preprints

Genome-wide nucleosome and transcription factor responses to genetic perturbations reveal chromatin-mediated mechanisms of transcriptional regulation.

Preprint · May 26, 2024 Epigenetic mechanisms contribute to gene regulation by altering chromatin accessibility through changes in transcription factor (TF) and nucleosome occupancy throughout the genome. Despite numerous studies focusing on changes in gene expression, the intric ... Full text Link to item Cite

Spatiotemporal kinetics of CAF-1-dependent chromatin maturation ensures transcription fidelity during S-phase.

Preprint · May 26, 2023 Full text Link to item Cite