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David Joseph Madden

Professor Emeritus in Psychiatry and Behavioral Sciences
Psychiatry & Behavioral Sciences, Behavioral Medicine & Neurosciences
Box 3918, Durham, NC 27710
40 Duke Medicine Circle, Room 414, Durham, NC 27710

Scholarly Works - Preprints


Distribution of paramagnetic and diamagnetic cortical substrates following mild Traumatic Brain Injury: A depth- and curvature-based quantitative susceptibility mapping study

Preprint · 2024 ABSTRACT Evidence has linked head trauma to increased risk factors for neuropathology, including acute mechanical deformation of the cortical sulcal fundus and, later, perivascular accumulation of hyperphosphorylated tau (p-tau) adjacent to these ... Full text Cite

Cortical iron-related markers are elevated in mild Traumatic Brain Injury: An individual-level quantitative susceptibility mapping study

Preprint · 2024 ABSTRACT Quantitative susceptibility mapping (QSM) has been applied to map brain iron distribution after mild traumatic brain in-jury (mTBI), to understand properties of neural tissue which may be related to microstructural damage. However, mTBI i ... Full text Cite

Age-related Macular Degeneration is associated with faster rates of structural brain changes and widespread differences in connectivity

Preprint · 2022 Age-related macular degeneration (AMD) is a prevalent disease impeding vision. More recently, AMD has also been linked to cognitive impairment, such as deficits in language and memory skills. In order to better understand the extent of AMD-related changes ... Full text Open Access Cite