David Alan Rizzieri | Scholars@Duke

David Alan Rizzieri
Professor of Medicine

My research interests focus on the care of patients with hematologic malignancies, both with and without the use of bone marrow or stem cell transplantation. I focus my research efforts on new approaches to manipulate minimal residual disease.

Recent endeavors have included:

Phase one trials with novel anti-cancer agents targeting aurora kinases, tyrosine kinases, mtor, VEGF, and raf/ras pathways
New monoclonal antibodies targeting tumor stroma rather than cellular antigens
Investigating new antibody targets, i.e. CD123, endoglin, or tenascin for hematologic malignancies
Aggressive therapy and transplantation for mantle cell lymphoma
Antiangiogenesis therapy for patients with NHL
Nonablative allogeneic transplantation therapy with matched or mismatched donors followed by immune modulation

Current Appointments & Affiliations

Professor of Medicine, Medicine, Hematologic Malignancies and Cellular Therapy, Medicine 2013
Member of the Duke Cancer Institute, Duke Cancer Institute, Institutes and Centers 1994

Contact Information

1149 N Pavilion, Durham, NC 27710
Box 3961 Med Ctr, Durham, NC 27710
david.rizzieri@duke.edu (919) 668-1040

Background
Education, Training, & Certifications
- Fellow in Hematology/Oncology, Medicine, Duke University 1994 - 1997
- Medical Resident, Medicine, Duke University 1991 - 1994
- M.D., University of Rochester 1991
Duke Appointment History
- Associate Professor of Medicine, Medicine, Hematologic Malignancies and Cellular Therapy, Medicine 2007 - 2013
- Associate Professor of Medicine, Medicine, Hematologic Malignancies and Cellular Therapy, Medicine 2003 - 2007
- Assistant Professor of Medicine, Medicine, Medical Oncology, Medicine 1998 - 2003
- Associate in the Department of Medicine, Medicine, Medical Oncology, Medicine 1997 - 1998
Research
Selected Grants
External Relationships
- AROG Pharmaceuticals
- AbbVie
- Amgen, Inc.
- Bayer
- Celgene Corporation
- Celltrion
- Cephalon, Inc. (Teva Pharmaceuticals)
- Chimerix, Inc.
- Gilead Sciences, Inc.
- Jazz Pharmaceuticals
- Kite pharmaceuticals
- Mustang
- Novartis
- Pfizer Inc.
- Pharmacyclics (AbbVie)
- Sanofi-Aventis
- Seattle Genetics
- Stemline
- acrobiotech
- incyte
- mustang bio
- ucart
Publications & Artistic Works
Selected Publications
- Academic Articles
  - Maung, Ko K., Benny J. Chen, Ian Barak, Zhiguo Li, David A. Rizzieri, Cristina Gasparetto, Keith M. Sullivan, et al. “Phase I dose escalation study of naive T-cell depleted donor lymphocyte infusion following allogeneic stem cell transplantation.” Bone Marrow Transplantation, July 5, 2020. https://doi.org/10.1038/s41409-020-0991-5.
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  - Markey, Kate A., Jonas Schluter, Antonio L. C. Gomes, Eric R. Littmann, Amanda J. Pickard, Bradford P. Taylor, Paul A. Giardina, et al. “The microbe-derived short-chain fatty acids butyrate and propionate are associated with protection from chronic GVHD.” Blood 136, no. 1 (July 2, 2020): 130–36. https://doi.org/10.1182/blood.2019003369.
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  - Goldberg, Aaron D., Ehab Atallah, David Rizzieri, Roland B. Walter, Ki-Young Chung, Alexander Spira, Wendy Stock, et al. “Camidanlumab tesirine, an antibody-drug conjugate, in relapsed/refractory CD25-positive acute myeloid leukemia or acute lymphoblastic leukemia: A phase I study.” Leuk Res 95 (June 7, 2020): 106385. https://doi.org/10.1016/j.leukres.2020.106385.
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  - Ghosh, Nilanjan, Sairah Ahmed, Kwang Woo Ahn, Manoj Khanal, Carlos Litovich, Mahmoud Aljurf, Vera Ulrike Bacher, et al. “Association of Reduced-Intensity Conditioning Regimens With Overall Survival Among Patients With Non-Hodgkin Lymphoma Undergoing Allogeneic Transplant.” Jama Oncol, June 4, 2020. https://doi.org/10.1001/jamaoncol.2020.1278.
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  - Pagel, John M., Megan Othus, Guillermo Garcia-Manero, Min Fang, Jerald P. Radich, David A. Rizzieri, Guido Marcucci, et al. “Rapid Donor Identification Improves Survival in High-Risk First-Remission Patients With Acute Myeloid Leukemia.” Jco Oncol Pract 16, no. 6 (June 2020): e464–75. https://doi.org/10.1200/JOP.19.00133.
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  - Sung, Anthony D., Shekeab Jauhari, Sharareh Siamakpour-Reihani, Arati V. Rao, Janet Staats, Cliburn Chan, Everett Meyer, et al. “Microtransplantation in older patients with AML: A pilot study of safety, efficacy and immunologic effects.” Am J Hematol 95, no. 6 (June 2020): 662–71. https://doi.org/10.1002/ajh.25781.
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  - Arnold, Staci D., Ruta Brazauskas, Naya He, Yimei Li, Matt Hall, Yoshiko Atsuta, Jignesh Dalal, et al. “The Impact of Donor Type on Outcomes and Cost of Allogeneic Hematopoietic Cell Transplantation for Pediatric Leukemia: A Merged Center for International Blood and Marrow Transplant Research and Pediatric Health Information System Analysis.” Biol Blood Marrow Transplant, May 25, 2020. https://doi.org/10.1016/j.bbmt.2020.05.016.
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  - Lazaryan, Aleksandr, Michelle Dolan, Mei-Jie Zhang, Hai-Lin Wang, Mohamed A. Kharfan-Dabaja, David I. Marks, Nelli Bejanyan, et al. “Impact of cytogenetic abnormalities on outcomes of adult Philadelphia-negative acute lymphoblastic leukemia after allogeneic hematopoietic stem cell transplantation: a study by the Acute Leukemia Working Committee of the Center for International Blood and Marrow Transplant Research.” Haematologica 105, no. 5 (May 2020): 1329–38. https://doi.org/10.3324/haematol.2019.220756.
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  - Economides, Minas P., David Rizzieri, and Naveen Pemmaraju. “Updates in Novel Therapies for Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN).” Curr Hematol Malig Rep 14, no. 6 (December 2019): 515–22. https://doi.org/10.1007/s11899-019-00556-2.
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  - Choi, Taewoong. “Is autologous stem cell transplantation still relevant for multiple myeloma?” Curr Opin Hematol 26, no. 6 (November 2019): 386–91. https://doi.org/10.1097/MOH.0000000000000538.
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  - Berdeja, Jesus G., Michael C. Heinrich, Shaker R. Dakhil, Stuart L. Goldberg, Martha Wadleigh, Philip Kuriakose, Jorge Cortes, et al. “Rates of deep molecular response by digital and conventional PCR with frontline nilotinib in newly diagnosed chronic myeloid leukemia: a landmark analysis.” Leuk Lymphoma 60, no. 10 (October 2019): 2384–93. https://doi.org/10.1080/10428194.2019.1590569.
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  - Kam, Angel Y. F., Sadhna O. Piryani, Chad M. McCall, Hee Su Park, David A. Rizzieri, and Phuong L. Doan. “Targeting High Mobility Group Box-1 (HMGB1) Promotes Cell Death in Myelodysplastic Syndrome.” Clin Cancer Res 25, no. 13 (July 1, 2019): 4155–67. https://doi.org/10.1158/1078-0432.CCR-18-3517.
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  - Rashidi, Armin, Mehdi Hamadani, Mei-Jie Zhang, Hai-Lin Wang, Hisham Abdel-Azim, Mahmoud Aljurf, Amer Assal, et al. “Outcomes of haploidentical vs matched sibling transplantation for acute myeloid leukemia in first complete remission.” Blood Adv 3, no. 12 (June 25, 2019): 1826–36. https://doi.org/10.1182/bloodadvances.2019000050.
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  - Lin, Kevin H., Abigail Xie, Justine C. Rutter, Yeong-Ran Ahn, Julia M. Lloyd-Cowden, Amanda G. Nichols, Ryan S. Soderquist, et al. “Systematic Dissection of the Metabolic-Apoptotic Interface in AML Reveals Heme Biosynthesis to Be a Regulator of Drug Sensitivity.” Cell Metab 29, no. 5 (May 7, 2019): 1217-1231.e7. https://doi.org/10.1016/j.cmet.2019.01.011.
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  - Pemmaraju, Naveen, Andrew A. Lane, Kendra L. Sweet, Anthony S. Stein, Sumithira Vasu, William Blum, David A. Rizzieri, et al. “Tagraxofusp in Blastic Plasmacytoid Dendritic-Cell Neoplasm.” N Engl J Med 380, no. 17 (April 25, 2019): 1628–37. https://doi.org/10.1056/NEJMoa1815105.
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  - Hudson, Kathryn E., David Rizzieri, Samantha M. Thomas, Thomas W. LeBlanc, Zachary Powell, Louis Diehl, Joseph O. Moore, Carlos DeCastro, and Anne W. Beaven. “Dose-intense chemoimmunotherapy plus radioimmunotherapy in high-risk diffuse large B-cell lymphoma and mantle cell lymphoma: a phase II study.” Br J Haematol 184, no. 4 (February 2019): 647–50. https://doi.org/10.1111/bjh.15138.
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  - Heyman, Benjamin, David Rizzieri, David J. Adams, Carlos De Castro, Louis Diehl, Zhiguo Li, Joseph Moore, and Anne Beaven. “Phase I Study of the Combination of Bendamustine, Rituximab, and Pixantrone in Patients With Relapsed/Refractory B-cell Non-Hodgkin Lymphoma.” Clin Lymphoma Myeloma Leuk 18, no. 10 (October 2018): 679–86. https://doi.org/10.1016/j.clml.2018.07.285.
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  - Zeidan, Amer M., Hanna A. Knaus, Tara M. Robinson, Andrea M. H. Towlerton, Edus H. Warren, Joshua F. Zeidner, Amanda L. Blackford, et al. “A Multi-center Phase I Trial of Ipilimumab in Patients with Myelodysplastic Syndromes following Hypomethylating Agent Failure.” Clin Cancer Res 24, no. 15 (August 1, 2018): 3519–27. https://doi.org/10.1158/1078-0432.CCR-17-3763.
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  - Sivaraj, Dharshan, Michael M. Green, Yubin Kang, Gwynn D. Long, David A. Rizzieri, Zhiguo Li, Anderson H. Garrett, Jackie L. McIntyre, Nelson J. Chao, and Cristina Gasparetto. “Bendamustine, pomalidomide, and dexamethasone for relapsed and/or refractory multiple myeloma.” Blood Cancer J 8, no. 8 (July 31, 2018): 71. https://doi.org/10.1038/s41408-018-0104-5.
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  - Stein, Eytan M., Guillermo Garcia-Manero, David A. Rizzieri, Raoul Tibes, Jesus G. Berdeja, Michael R. Savona, Mojca Jongen-Lavrenic, et al. “The DOT1L inhibitor pinometostat reduces H3K79 methylation and has modest clinical activity in adult acute leukemia.” Blood 131, no. 24 (June 14, 2018): 2661–69. https://doi.org/10.1182/blood-2017-12-818948.
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  - Casulo, Carla, Jonathan W. Friedberg, Kwang W. Ahn, Christopher Flowers, Alyssa DiGilio, Sonali M. Smith, Sairah Ahmed, et al. “Autologous Transplantation in Follicular Lymphoma with Early Therapy Failure: A National LymphoCare Study and Center for International Blood and Marrow Transplant Research Analysis.” Biol Blood Marrow Transplant 24, no. 6 (June 2018): 1163–71. https://doi.org/10.1016/j.bbmt.2017.12.771.
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  - Kebriaei, Partow, Claudio Anasetti, Mei-Jie Zhang, Hai-Lin Wang, Ibrahim Aldoss, Marcos de Lima, H Jean Khoury, et al. “Intravenous Busulfan Compared with Total Body Irradiation Pretransplant Conditioning for Adults with Acute Lymphoblastic Leukemia.” Biol Blood Marrow Transplant 24, no. 4 (April 2018): 726–33. https://doi.org/10.1016/j.bbmt.2017.11.025.
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  - Roboz, Gail J., Hagop M. Kantarjian, Karen W. L. Yee, Patricia L. Kropf, Casey L. O’Connell, Elizabeth A. Griffiths, Wendy Stock, et al. “Dose, schedule, safety, and efficacy of guadecitabine in relapsed or refractory acute myeloid leukemia.” Cancer 124, no. 2 (January 15, 2018): 325–34. https://doi.org/10.1002/cncr.31138.
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  - Guo, Mei, Nelson J. Chao, Jian-Yong Li, David A. Rizzieri, Qi-Yun Sun, Ann Mohrbacher, Elizabeth F. Krakow, et al. “HLA-Mismatched Microtransplant in Older Patients Newly Diagnosed With Acute Myeloid Leukemia: Results From the Microtransplantation Interest Group.” Jama Oncol 4, no. 1 (January 1, 2018): 54–62. https://doi.org/10.1001/jamaoncol.2017.2656.
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  - O’Brien, J., T. Rizzieri, and D. Rizzieri. “Recombinant human fusion protein of diphtheria toxin and IL-3 treatment of blastic plasmacytoid dendritic cell neoplasm.” Drugs of the Future 43, no. 12 (January 1, 2018): 873–80. https://doi.org/10.1358/dof.2018.043.12.2898664.
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  - Sivaraj, D., W. Bacon, G. D. Long, D. A. Rizzieri, M. E. Horwitz, K. M. Sullivan, Y. Kang, Z. Li, N. J. Chao, and C. Gasparetto. “High-dose BCNU/Melphalan conditioning regimen before autologous stem cell transplantation in newly diagnosed multiple myeloma.” Bone Marrow Transplant 53, no. 1 (January 2018): 34–38. https://doi.org/10.1038/bmt.2017.208.
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  - Wong, Hong Yuen, Anthony D. Sung, Katherine E. Lindblad, Sheenu Sheela, Gregory W. Roloff, David Rizzieri, Meghali Goswami, et al. “Molecular Measurable Residual Disease Testing of Blood During AML Cytotoxic Therapy for Early Prediction of Clinical Response.” Front Oncol 8 (2018): 669. https://doi.org/10.3389/fonc.2018.00669.
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  - Huang, Li-Wen, Wendi Bacon, Constance Cirrincione, Bercedis Peterson, Gwynn Long, David Rizzieri, Keith M. Sullivan, et al. “Efficacy and safety of high-dose chemotherapy with autologous stem cell transplantation in senior versus younger adults with newly diagnosed multiple myeloma.” Hematol Oncol 35, no. 4 (December 2017): 752–59. https://doi.org/10.1002/hon.2379.
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  - Kantarjian, Hagop M., Gail J. Roboz, Patricia L. Kropf, Karen W. L. Yee, Casey L. O’Connell, Raoul Tibes, Katherine J. Walsh, et al. “Guadecitabine (SGI-110) in treatment-naive patients with acute myeloid leukaemia: phase 2 results from a multicentre, randomised, phase 1/2 trial.” Lancet Oncol 18, no. 10 (October 2017): 1317–26. https://doi.org/10.1016/S1470-2045(17)30576-4.
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  - Muffly, Lori, Marcelo C. Pasquini, Michael Martens, Ruta Brazauskas, Xiaochun Zhu, Kehinde Adekola, Mahmoud Aljurf, et al. “Increasing use of allogeneic hematopoietic cell transplantation in patients aged 70 years and older in the United States.” Blood 130, no. 9 (August 31, 2017): 1156–64. https://doi.org/10.1182/blood-2017-03-772368.
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  - Batlevi, Connie L., Michael Crump, Charalambos Andreadis, David Rizzieri, Sarit E. Assouline, Susan Fox, Richard H. C. van der Jagt, et al. “A phase 2 study of mocetinostat, a histone deacetylase inhibitor, in relapsed or refractory lymphoma.” Br J Haematol 178, no. 3 (August 2017): 434–41. https://doi.org/10.1111/bjh.14698.
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  - Boss, M. K., M. W. Dewhirst, R. S. Sampaio, A. Bennett, A. Tovmasyan, K. G. Berman, A. W. Beaven, et al. “Potential for a novel manganese porphyrin compound as adjuvant canine lymphoma therapy.” Cancer Chemother Pharmacol 80, no. 2 (August 2017): 421–31. https://doi.org/10.1007/s00280-017-3372-z.
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  - Anand, Sarah, Samantha Thomas, Terry Hyslop, Janet Adcock, Kelly Corbet, Cristina Gasparetto, Richard Lopez, et al. “Transplantation of Ex Vivo Expanded Umbilical Cord Blood (NiCord) Decreases Early Infection and Hospitalization.” Biol Blood Marrow Transplant 23, no. 7 (July 2017): 1151–57. https://doi.org/10.1016/j.bbmt.2017.04.001.
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  - Michelis, Fotios V., Vikas Gupta, Mei-Jie Zhang, Hai-Lin Wang, Mahmoud Aljurf, Ulrike Bacher, Amer Beitinjaneh, et al. “Cytogenetic risk determines outcomes after allogeneic transplantation in older patients with acute myeloid leukemia in their second complete remission: A Center for International Blood and Marrow Transplant Research cohort analysis.” Cancer 123, no. 11 (June 1, 2017): 2035–42. https://doi.org/10.1002/cncr.30567.
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  - El-Jawahri, Areej, Yi-Bin Chen, Ruta Brazauskas, Naya He, Stephanie J. Lee, Jennifer M. Knight, Navneet Majhail, et al. “Impact of pre-transplant depression on outcomes of allogeneic and autologous hematopoietic stem cell transplantation.” Cancer 123, no. 10 (May 15, 2017): 1828–38. https://doi.org/10.1002/cncr.30546.
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  - Liu, Hien Duong, Kwang Woo Ahn, Zhen-Huan Hu, Mehdi Hamadani, Taiga Nishihori, Baldeep Wirk, Amer Beitinjaneh, et al. “Allogeneic Hematopoietic Cell Transplantation for Adult Chronic Myelomonocytic Leukemia.” Biol Blood Marrow Transplant 23, no. 5 (May 2017): 767–75. https://doi.org/10.1016/j.bbmt.2017.01.078.
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  - Sivaraj, Dharshan, Michael M. Green, Zhiguo Li, Anthony D. Sung, Stefanie Sarantopoulos, Yubin Kang, Gwynn D. Long, et al. “Outcomes of Maintenance Therapy with Bortezomib after Autologous Stem Cell Transplantation for Patients with Multiple Myeloma.” Biol Blood Marrow Transplant 23, no. 2 (February 2017): 262–68. https://doi.org/10.1016/j.bbmt.2016.11.010.
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  - Sullivan, Jill M., and David A. Rizzieri. “Treatment of blastic plasmacytoid dendritic cell neoplasm.” Hematology Am Soc Hematol Educ Program 2016, no. 1 (December 2, 2016): 16–23. https://doi.org/10.1182/asheducation-2016.1.16.
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  - Bajaj, Jeevisha, Takaaki Konuma, Nikki K. Lytle, Hyog Young Kwon, Jailal N. Ablack, Joseph M. Cantor, David Rizzieri, et al. “CD98-Mediated Adhesive Signaling Enables the Establishment and Propagation of Acute Myelogenous Leukemia.” Cancer Cell 30, no. 5 (November 14, 2016): 792–805. https://doi.org/10.1016/j.ccell.2016.10.003.
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  - Sung, Anthony D., Julia A. M. Sung, Samantha Thomas, Terry Hyslop, Cristina Gasparetto, Gwynn Long, David Rizzieri, et al. “Universal Mask Usage for Reduction of Respiratory Viral Infections After Stem Cell Transplant: A Prospective Trial.” Clin Infect Dis 63, no. 8 (October 15, 2016): 999–1006. https://doi.org/10.1093/cid/ciw451.
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  - Zahid, Mohammad Faizan, Mrinal M. Patnaik, Naseema Gangat, Shahrukh K. Hashmi, and David A. Rizzieri. “Insight into the molecular pathophysiology of myelodysplastic syndromes: targets for novel therapy.” Eur J Haematol 97, no. 4 (October 2016): 313–20. https://doi.org/10.1111/ejh.12771.
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  - Rizzieri, David. “Zevalin(®) (ibritumomab tiuxetan): After more than a decade of treatment experience, what have we learned?” Crit Rev Oncol Hematol 105 (September 2016): 5–17. https://doi.org/10.1016/j.critrevonc.2016.07.008.
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  - Green, Michael M. B., Nelson Chao, Saurabh Chhabra, Kelly Corbet, Cristina Gasparetto, Ari Horwitz, Zhiguo Li, et al. “Plerixafor (a CXCR4 antagonist) following myeloablative allogeneic hematopoietic stem cell transplantation enhances hematopoietic recovery.” J Hematol Oncol 9, no. 1 (August 17, 2016): 71. https://doi.org/10.1186/s13045-016-0301-2.
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  - Rizzieri, David A., Sarah Cooley, Olatoyosi Odenike, Lisette Moonan, Kay Hoong Chow, Kimberley Jackson, Xuejing Wang, Leslie Brail, and Gautam Borthakur. “An open-label phase 2 study of glycogen synthase kinase-3 inhibitor LY2090314 in patients with acute leukemia.” Leuk Lymphoma 57, no. 8 (August 2016): 1800–1806. https://doi.org/10.3109/10428194.2015.1122781.
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  - Shaffer, Brian C., Kwang Woo Ahn, Zhen-Huan Hu, Taiga Nishihori, Adriana K. Malone, David Valcárcel, Michael R. Grunwald, et al. “Scoring System Prognostic of Outcome in Patients Undergoing Allogeneic Hematopoietic Cell Transplantation for Myelodysplastic Syndrome.” J Clin Oncol 34, no. 16 (June 1, 2016): 1864–71. https://doi.org/10.1200/JCO.2015.65.0515.
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  - Zahid, Mohammad Faizan, and David Alan Rizzieri. “Haploidentical Hematopoietic Stem Cell Transplantation: Expanding the Horizon for Hematologic Disorders.” Adv Hematol 2016 (2016): 1423493. https://doi.org/10.1155/2016/1423493.
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  - Urbano-Ispizua, Alvaro, Steven Z. Pavletic, Mary E. Flowers, John P. Klein, Mei-Jie Zhang, Jeanette Carreras, Silvia Montoto, et al. “The Impact of Graft-versus-Host Disease on the Relapse Rate in Patients with Lymphoma Depends on the Histological Subtype and the Intensity of the Conditioning Regimen.” Biol Blood Marrow Transplant 21, no. 10 (October 2015): 1746–53. https://doi.org/10.1016/j.bbmt.2015.05.010.
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  - Griffin, Patrick T., Rami S. Komrokji, Carlos M. De Castro, David A. Rizzieri, Magda Melchert, Alan F. List, and Jeffrey E. Lancet. “A multicenter, phase II study of maintenance azacitidine in older patients with acute myeloid leukemia in complete remission after induction chemotherapy.” Am J Hematol 90, no. 9 (September 2015): 796–99. https://doi.org/10.1002/ajh.24087.
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  - Issa, Jean-Pierre J., Gail Roboz, David Rizzieri, Elias Jabbour, Wendy Stock, Casey O’Connell, Karen Yee, et al. “Safety and tolerability of guadecitabine (SGI-110) in patients with myelodysplastic syndrome and acute myeloid leukaemia: a multicentre, randomised, dose-escalation phase 1 study.” Lancet Oncol 16, no. 9 (September 2015): 1099–1110. https://doi.org/10.1016/S1470-2045(15)00038-8.
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  - Kwon, Hyog Young, Jeevisha Bajaj, Takahiro Ito, Allen Blevins, Takaaki Konuma, Joi Weeks, Nikki K. Lytle, et al. “Tetraspanin 3 Is Required for the Development and Propagation of Acute Myelogenous Leukemia.” Cell Stem Cell 17, no. 2 (August 6, 2015): 152–64. https://doi.org/10.1016/j.stem.2015.06.006.
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  - Tuchman, Sascha A., Wendi A. Bacon, Li-Wen Huang, Gwynn Long, David Rizzieri, Mitchell Horwitz, John P. Chute, et al. “Cyclophosphamide-based hematopoietic stem cell mobilization before autologous stem cell transplantation in newly diagnosed multiple myeloma.” J Clin Apher 30, no. 3 (June 2015): 176–82. https://doi.org/10.1002/jca.21360.
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  - Davis, C. T., and D. Rizzieri. “Immunotherapeutic applications of NK cells.” Pharmaceuticals 8, no. 2 (May 8, 2015): 250–56. https://doi.org/10.3390/ph8020250.
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  - Stone, Richard M., Emanuele Mazzola, Donna Neuberg, Steven L. Allen, Arnaud Pigneux, Robert K. Stuart, Meir Wetzler, et al. “Phase III open-label randomized study of cytarabine in combination with amonafide L-malate or daunorubicin as induction therapy for patients with secondary acute myeloid leukemia.” J Clin Oncol 33, no. 11 (April 10, 2015): 1252–57. https://doi.org/10.1200/JCO.2014.57.0952.
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  - Bachanova, V., L. J. Burns, T. Wang, J. Carreras, R. P. Gale, P. H. Wiernik, K. K. Ballen, et al. “Alternative donors extend transplantation for patients with lymphoma who lack an HLA matched donor.” Bone Marrow Transplantation 50, no. 2 (February 7, 2015): 197–203. https://doi.org/10.1038/bmt.2014.259.
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  - Bachanova, V., L. J. Burns, T. Wang, J. Carreras, R. P. Gale, P. H. Wiernik, K. K. Ballen, et al. “Alternative donors extend transplantation for patients with lymphoma who lack an HLA matched donor.” Bone Marrow Transplant 50, no. 2 (February 2015): 197–203. https://doi.org/10.1038/bmt.2014.259.
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  - Chen, Weihong, David Rizzieri, and Susan Drago. “Safety of growth factor administration for leukapheresis in those with WBC counts greater than 60,000/µl.” J Clin Apher 30, no. 1 (February 2015): 28–31. https://doi.org/10.1002/jca.21343.
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  - Stein, Eytan M., Guillermo Garcia-Manero, David A. Rizzieri, Michael Savona, Raoul Tibes, Jessica K. Altman, Mojca Jongen-Lavrencic, et al. “The DOT1L Inhibitor EPZ-5676: Safety and Activity in Relapsed/Refractory Patients with MLL-Rearranged Leukemia.” Blood 124, no. 21 (December 6, 2014).
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  - Rein, Lindsay A. M., and David A. Rizzieri. “Clinical potential of elacytarabine in patients with acute myeloid leukemia.” Ther Adv Hematol 5, no. 6 (December 2014): 211–20. https://doi.org/10.1177/2040620714552615.
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  - Hamadani, Mehdi, Parameswaran N. Hari, Ying Zhang, Jeanette Carreras, Görgün Akpek, Mahmoud D. Aljurf, Ernesto Ayala, et al. “Early failure of frontline rituximab-containing chemo-immunotherapy in diffuse large B cell lymphoma does not predict futility of autologous hematopoietic cell transplantation.” Biol Blood Marrow Transplant 20, no. 11 (November 2014): 1729–36. https://doi.org/10.1016/j.bbmt.2014.06.036.
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  - Liu, T., R. J. Kishton, A. N. Macintyre, V. A. Gerriets, H. Xiang, X. Liu, E. D. Abel, D. Rizzieri, J. W. Locasale, and J. C. Rathmell. “Glucose transporter 1-mediated glucose uptake is limiting for B-cell acute lymphoblastic leukemia anabolic metabolism and resistance to apoptosis.” Cell Death Dis 5 (October 16, 2014): e1470. https://doi.org/10.1038/cddis.2014.431.
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  - Rizzieri, David, Norbert Vey, Xavier Thomas, Françoise Huguet-Rigal, Richard F. Schlenk, Jürgen Krauter, Thomas Kindler, et al. “A phase II study of elacytarabine in combination with idarubicin and of human equilibrative nucleoside transporter 1 expression in patients with acute myeloid leukemia and persistent blasts after the first induction course.” Leuk Lymphoma 55, no. 9 (September 2014): 2114–19. https://doi.org/10.3109/10428194.2013.867489.
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  - Horwitz, Mitchell E., Nelson J. Chao, David A. Rizzieri, Gwynn D. Long, Keith M. Sullivan, Cristina Gasparetto, John P. Chute, et al. “Umbilical cord blood expansion with nicotinamide provides long-term multilineage engraftment.” J Clin Invest 124, no. 7 (July 2014): 3121–28. https://doi.org/10.1172/JCI74556.
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  - Wirk, Baldeep, Timothy S. Fenske, Mehdi Hamadani, Mei-Jie Zhang, Zhen-Huan Hu, Görgün Akpek, Mahmoud D. Aljurf, et al. “Outcomes of hematopoietic cell transplantation for diffuse large B cell lymphoma transformed from follicular lymphoma.” Biol Blood Marrow Transplant 20, no. 7 (July 2014): 951–59. https://doi.org/10.1016/j.bbmt.2014.03.014.
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  - Prince, H Miles, Dirk Hönemann, Andrew Spencer, David A. Rizzieri, Edward A. Stadtmauer, Andrew W. Roberts, Nizar Bahlis, et al. “Vascular endothelial growth factor inhibition is not an effective therapeutic strategy for relapsed or refractory multiple myeloma: a phase 2 study of pazopanib (GW786034).” Blood 113, no. 19 (May 7, 2009): 4819–20. https://doi.org/10.1182/blood-2009-02-207209.
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  - Zhang, Jenny, Dereje D. Jima, Cassandra Jacobs, Randy Fischer, Eva Gottwein, Grace Huang, Patricia L. Lugar, et al. “Patterns of microRNA expression characterize stages of human B-cell differentiation.” Blood 113, no. 19 (May 7, 2009): 4586–94. https://doi.org/10.1182/blood-2008-09-178186.
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  - Castro, C. de, D. Adams, D. Rizzieri, J. Moore, J. Gockerman, L. Diehl, M. Horwitz, E. Edmonds, and J. Warzecho. “P134 A phase II pilot study of sorafenib in patients with myelodysplastic syndromes.” Leukemia Research 33, no. SUPPL. 1 (May 1, 2009). https://doi.org/10.1016/S0145-2126(09)70215-2.
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  - Shea, Thomas C., Anne W. Beaven, Dominic T. Moore, Jonathan S. Serody, Don A. Gabriel, Nelson Chao, Jon P. Gockerman, Reynaldo A. Garcia, and David A. Rizzieri. “Sequential high-dose ifosfamide, carboplatin and etoposide with rituximab for relapsed Hodgkin and large B-cell non-Hodgkin lymphoma: increased toxicity without improvement in progression-free survival.” Leuk Lymphoma 50, no. 5 (May 2009): 741–48. https://doi.org/10.1080/10428190902853136.
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  - Zhao, Chen, Alan Chen, Catriona H. Jamieson, Mark Fereshteh, Annelie Abrahamsson, Jordan Blum, Hyog Young Kwon, et al. “Hedgehog signalling is essential for maintenance of cancer stem cells in myeloid leukaemia.” Nature 458, no. 7239 (April 9, 2009): 776–79. https://doi.org/10.1038/nature07737.
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  - Rizzieri, D. A., P. Dev, G. D. Long, C. Gasparetto, K. M. Sullivan, Ml Horwitz, J. Chute, and N. J. Chao. “Response and toxicity of donor lymphocyte infusions following T-cell depleted non-myeloablative allogeneic hematopoietic SCT from 3-6/6 HLA matched donors.” Bone Marrow Transplant 43, no. 4 (February 2009): 327–33. https://doi.org/10.1038/bmt.2008.321.
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  - Weinberg, J. B., A. D. Volkheimer, M. Mihovilovic, N. Jiang, Y. Chen, K. Bond, J. O. Moore, et al. “Apolipoprotein E genotype as a determinant of survival in chronic lymphocytic leukemia.” Leukemia 22, no. 12 (December 2008): 2184–92. https://doi.org/10.1038/leu.2008.241.
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  - Allen, Steven L., Harry P. Erba, David A. Rizzieri, Margaret O’Donnell, Bayard Powell, Ante S. Lundberg, John M. Bennett, and Robert L. Capizzi. “Secondary Acute Myeloid Leukemia (sAML) Treated with Amonafide (AS1413) + Cytarabine: Durable Responses in Poor-Risk AML.” Blood 112, no. 11 (November 16, 2008): 1019–20.
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  - Gasparet, Cristina, Jon P. Gockerman, Louis F. Diehl, Carlos De Castro, Joseph Moore, Gwynn D. Long, Mitchell Horwitz, et al. “Bortezomib Plus Melphalan and Prednisone as Induction Prior to Transplant or as Frontline Therapy for Non-Transplant Candidates in Patients with Previously Untreated Multiple Myeloma.” Blood 112, no. 11 (November 16, 2008): 1142–1142.
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  - O’Brien, Susan, David A. Rizzieri, Norbert Vey, Hagop M. Kantarjian, Tove Flem Jacobsen, Bo I. Nilsson, Karin Staudacher, and Francis Giles. “A Phase I/II Study with CP-4055 in Patients with Haematologic Malignancies.” Blood 112, no. 11 (November 16, 2008): 350–350.
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  - Prasad, Vinod K., Dong-Feng Chen, Gloria Broadwater, Nancy L. Reinsmoen, Adella Clark, Nelson J. Chao, and David A. Rizzieri. “Differential Impact of Inhibitory and Activating Killer Ig-Like Receptors and HLA Ligand on Outcomes of Transplantation for Myeloid and Lymphoid Malignancies.” Blood 112, no. 11 (November 16, 2008): 1118–1118.
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  - Rao, Arati V., Sascha A. Tuchman, Anil Potti, David A. Rizzieri, Hiroyuki Mano, Ruud Delwel, Peter Valk, and B. Lowenberg. “Gene Expression Profiles with Signatures of Tumor Biology and Chemotherapy Sensitivity May Provide a Novel Approach to Maximize Response to Induction Therapy in Patients with Acute Myeloid Leukemia.” Blood 112, no. 11 (November 16, 2008): 785–86.
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  - Rizzieri, Davd A., Robert Storms, Daniel Nikcevich, Bercedis Peterson, Debashish Misra, Christine Apple, Megan Baker, et al. “Safety Trial of NK Cell Enhanced Donor Lymphocyte Infusions from a 3-5/6 HLA Matched Family Member Following Nonmyeloablative Allogeneic Stem Cell Transplantation.” Blood 112, no. 11 (November 16, 2008): 133–34.
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  - Zhang, Jenny, Dereje D. Jima, Cassandra L. Jacobs, Eva Gottwein, Grace Huang, Patricia L. Lugar, Anand S. Lagoo, David A. Rizzieri, Peter E. Lipsky, and Sandeep S. Dave. “MicroRNAs Regulate Mature B Cell Differentiation.” Blood 112, no. 11 (November 16, 2008): 262–262.
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  - Lee, Stephanie J., Manisha Kukreja, Tao Wang, Sergio A. Giralt, Jeffrey Szer, Mukta Arora, Ann E. Woolfrey, et al. “Impact of prior imatinib mesylate on the outcome of hematopoietic cell transplantation for chronic myeloid leukemia.” Blood 112, no. 8 (October 15, 2008): 3500–3507. https://doi.org/10.1182/blood-2008-02-141689.
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  - Rao, Arati V., Islam R. Younis, Gregory J. Sand, Ivan Spasojevic, David J. Adams, Carlos M. Decastro, John P. Gockerman, et al. “Phase I evaluation of gemcitabine, mitoxantrone, and their effect on plasma disposition of fludarabine in patients with relapsed or refractory acute myeloid leukemia.” Leuk Lymphoma 49, no. 8 (August 2008): 1523–29. https://doi.org/10.1080/10428190802210700.
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  - Nicolini, F. E., G. Alimena, H. Al-Ali, A. Y. Zaritskey, Z. Shen, S. Jootar, G. Smith, Y. Hsu, M. L. Veronese, and D. A. Rizzieri. “Expanding Nilotinib Access in Clinical Trials (ENACT) study in adult patients with imatinib-resistant or -intolerant Philadelphia chromosome-positive (Ph+) chronic myelogenous leukemia (CML) in chronic phase (CP), accelerated phase (AP), or blast crisis (BC): Updated safety analysis.” Journal of Clinical Oncology 26, no. 15_suppl (May 20, 2008): 7059–7059. https://doi.org/10.1200/jco.2008.26.15_suppl.7059.
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  - Rizzieri, D. A., H. P. Erba, M. O’Donnell, B. L. Powell, A. S. Lundberg, J. M. Bennett, and R. L. Capizzi. “Amonafide + ara-C in secondary acute myeloid leukemia (sAML): Consistent efficacy in poor risk populations.” Journal of Clinical Oncology 26, no. 15_suppl (May 20, 2008): 7027–7027. https://doi.org/10.1200/jco.2008.26.15_suppl.7027.
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  - Horwitz, Mitchell E., Ashley Morris, Cristina Gasparetto, Keith Sullivan, Gwynn Long, John Chute, David Rizzieri, Jackie McPherson, and Nelson Chao. “Myeloablative intravenous busulfan/fludarabine conditioning does not facilitate reliable engraftment of dual umbilical cord blood grafts in adult recipients.” Biol Blood Marrow Transplant 14, no. 5 (May 2008): 591–94. https://doi.org/10.1016/j.bbmt.2008.02.016.
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  - Rizzieri, David A., Eric Feldman, John F. Dipersio, Nashat Gabrail, Wendy Stock, Roger Strair, Victor M. Rivera, Maher Albitar, Camille L. Bedrosian, and Francis J. Giles. “A phase 2 clinical trial of deforolimus (AP23573, MK-8669), a novel mammalian target of rapamycin inhibitor, in patients with relapsed or refractory hematologic malignancies.” Clin Cancer Res 14, no. 9 (May 1, 2008): 2756–62. https://doi.org/10.1158/1078-0432.CCR-07-1372.
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  - Adams, David J., Marit L. Sandvold, Finn Myhren, Tove F. Jacobsen, Frank Giles, and David A. Rizzieri. “Anti proliferative activity of ELACY (CP-4055) in combination with cloretazine (VNP40101M), idarubicin, gemcitabine, irinotecan and topotecan in human leukemia and lymphoma cells.” Leuk Lymphoma 49, no. 4 (April 2008): 786–97. https://doi.org/10.1080/10428190801935752.
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  - Frankel, Arthur, Jen-Sing Liu, David Rizzieri, and Donna Hogge. “Phase I clinical study of diphtheria toxin-interleukin 3 fusion protein in patients with acute myeloid leukemia and myelodysplasia.” Leuk Lymphoma 49, no. 3 (March 2008): 543–53. https://doi.org/10.1080/10428190701799035.
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  - Smith, Sonali M., David Grinblatt, Jeffrey L. Johnson, Donna Niedzwiecki, David Rizzieri, Nancy L. Bartlett, Bruce D. Cheson, and Bruce D. Cancer and Leukemia Group B. “Thalidomide has limited single-agent activity in relapsed or refractory indolent non-Hodgkin lymphomas: a phase II trial of the Cancer and Leukemia Group B.” Br J Haematol 140, no. 3 (February 2008): 313–19. https://doi.org/10.1111/j.1365-2141.2007.06937.x.
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  - Byrne, B. J., M. Horwitz, G. D. Long, C. Gasparetto, K. M. Sullivan, J. Chute, N. J. Chao, and D. A. Rizzieri. “Outcomes of a second non-myeloablative allogeneic stem cell transplantation following graft rejection.” Bone Marrow Transplant 41, no. 1 (January 2008): 39–43. https://doi.org/10.1038/sj.bmt.1705882.
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  - Hobeika, Ac, T. Osada, D. Serra, S. Peplinski, K. Hanson, Y. Tanaka, D. Niedzwiecki, et al. “Detailed analysis of cytomegalovirus (CMV)-specific T cells expanded for adoptive immunotherapy of CMV infection following allogeneic stem cell transplantation for malignant disease.” Cytotherapy 10, no. 3 (2008): 289–302. https://doi.org/10.1080/14653240801927040.
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  - Horwitz, Mitchell E., Ivan Spasojevic, Ashley Morris, Marilyn Telen, James Essell, Cristina Gasparetto, Keith Sullivan, et al. “Fludarabine-based nonmyeloablative stem cell transplantation for sickle cell disease with and without renal failure: clinical outcome and pharmacokinetics.” Biol Blood Marrow Transplant 13, no. 12 (December 2007): 1422–26. https://doi.org/10.1016/j.bbmt.2007.08.050.
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  - Weinberg, J Brice, Alicia D. Volkheimer, Youwei Chen, Bethany E. Beasley, Ning Jiang, Mark C. Lanasa, Daphne Friedman, et al. “Clinical and molecular predictors of disease severity and survival in chronic lymphocytic leukemia.” Am J Hematol 82, no. 12 (December 2007): 1063–70. https://doi.org/10.1002/ajh.20987.
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  - Koh, Liang-Piu, David A. Rizzieri, and Nelson J. Chao. “Allogeneic hematopoietic stem cell transplant using mismatched/haploidentical donors.” Biol Blood Marrow Transplant 13, no. 11 (November 2007): 1249–67. https://doi.org/10.1016/j.bbmt.2007.08.003.
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  - Rizzieri, David A., Liang Piu Koh, Gwynn D. Long, Cristina Gasparetto, Keith M. Sullivan, Mitchell Horwitz, John Chute, et al. “Partially matched, nonmyeloablative allogeneic transplantation: clinical outcomes and immune reconstitution.” J Clin Oncol 25, no. 6 (February 20, 2007): 690–97. https://doi.org/10.1200/JCO.2006.07.0953.
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  - Giles, Francis, David Rizzieri, Judith Karp, Norbert Vey, Farhad Ravandi, Stefan Faderl, Khuda Dad Khan, et al. “Cloretazine (VNP40101M), a novel sulfonylhydrazine alkylating agent, in patients age 60 years or older with previously untreated acute myeloid leukemia.” J Clin Oncol 25, no. 1 (January 1, 2007): 25–31. https://doi.org/10.1200/JCO.2006.07.0961.
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  - Lagoo, Anand S., Jerald Z. Gong, Timothy T. Stenzel, Barbara K. Goodman, Patrick J. Buckley, Nelson J. Chao, Cristina Gasparetto, Gwynn D. Long, and David A. Rizzieri. “Morphologic examination of sequential bone marrow biopsies after nonmyeloablative stem cell transplantation complements molecular studies of donor engraftment.” Arch Pathol Lab Med 130, no. 10 (October 2006): 1479–88. https://doi.org/10.1043/1543-2165(2006)130[1479:MEOSBM]2.0.CO;2.
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  - Schiller, Gary J., James Slack, John D. Hainsworth, James Mason, Mansoor Saleh, David Rizzieri, Dan Douer, and Alan F. List. “Phase II multicenter study of arsenic trioxide in patients with myelodysplastic syndromes.” J Clin Oncol 24, no. 16 (June 1, 2006): 2456–64. https://doi.org/10.1200/JCO.2005.03.7903.
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  - Vredenburgh, James J., David Coniglio, Gloria Broadwater, Roy B. Jones, Maureen Ross, Elizabeth J. Shpall, Atif Hussein, et al. “Consolidation with high-dose combination alkylating agents with bone marrow transplantation significantly improves disease-free survival in hormone-insensitive metastatic breast cancer in complete remission compared with intensive standard-dose chemotherapy alone.” Biol Blood Marrow Transplant 12, no. 2 (February 2006): 195–203. https://doi.org/10.1016/j.bbmt.2005.10.009.
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  - Dannull, Jens, Zhen Su, David Rizzieri, Benjamin K. Yang, Doris Coleman, Donna Yancey, Aijing Zhang, et al. “Enhancement of vaccine-mediated antitumor immunity in cancer patients after depletion of regulatory T cells.” J Clin Invest 115, no. 12 (December 2005): 3623–33. https://doi.org/10.1172/JCI25947.
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  - Rizzieri, David A., Martha Wadleigh, Carol J. Wikstrand, Karen P. Mann, Filiz Sen, Bercedis L. Peterson, Donna Niedzwiecki, Alan D. Proia, and Darell D. Bigner. “Tenascin and microvessel stromal changes in patients with non-Hodgkin's lymphoma are isolated to the sites of disease and vary in correlation to disease activity.” Leuk Lymphoma 46, no. 10 (October 2005): 1455–62. https://doi.org/10.1080/10428190500158060.
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  - Shanks, Ryan H., David A. Rizzieri, James L. Flowers, O Michael Colvin, and David J. Adams. “Preclinical evaluation of gemcitabine combination regimens for application in acute myeloid leukemia.” Clin Cancer Res 11, no. 11 (June 1, 2005): 4225–33. https://doi.org/10.1158/1078-0432.CCR-04-2106.
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  - Nieto, Yago, James J. Vredenburgh, Elizabeth J. Shpall, Scott I. Bearman, Peter A. McSweeney, Nelson Chao, David Rizzieri, et al. “Phase II feasibility and pharmacokinetic study of concurrent administration of trastuzumab and high-dose chemotherapy in advanced HER2+ breast cancer.” Clin Cancer Res 10, no. 21 (November 1, 2004): 7136–43. https://doi.org/10.1158/1078-0432.CCR-04-0891.
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  - Gasparetto, Maura, Tracy Gentry, Said Sebti, Erica O’Bryan, Ramadevi Nimmanapalli, Michelle A. Blaskovich, Kapil Bhalla, et al. “Identification of compounds that enhance the anti-lymphoma activity of rituximab using flow cytometric high-content screening.” J Immunol Methods 292, no. 1–2 (September 2004): 59–71. https://doi.org/10.1016/j.jim.2004.06.003.
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  - Talbot, Jeffrey, Valerie K. Ibom, David A. Rizzieri, Robert Barrier, Donna Niedzwieki, Carlos M. DeCastro, Joseph O. Moore, et al. “Dose-intense cyclophosphamide and etoposide for patients with refractory or high-risk non-Hodgkin's lymphoma.” Clin Lymphoma 5, no. 2 (September 2004): 116–22. https://doi.org/10.3816/clm.2004.n.018.
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  - Bhagat, Rajesh, David A. Rizzieri, James J. Vredenburgh, Nelson J. Chao, and Rodney J. Folz. “Pulmonary sarcoidosis following stem cell transplantation: is it more than a chance occurrence?” Chest 126, no. 2 (August 2004): 642–44. https://doi.org/10.1378/chest.126.2.642.
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  - Chao, Nelson J., Liang-Piu Koh, Gwynn D. Long, Cristina Gasparetto, Mitchell Horwitz, Ashley Morris, Martha Lassiter, Keith M. Sullivan, and David A. Rizzieri. “Adult recipients of umbilical cord blood transplants after nonmyeloablative preparative regimens.” Biol Blood Marrow Transplant 10, no. 8 (August 2004): 569–75. https://doi.org/10.1016/j.bbmt.2004.05.001.
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  - Rizzieri, David A., Gamal Akabani, Michael R. Zalutsky, R Edward Coleman, Scott D. Metzler, James E. Bowsher, Bonnie Toaso, et al. “Phase 1 trial study of 131I-labeled chimeric 81C6 monoclonal antibody for the treatment of patients with non-Hodgkin lymphoma.” Blood 104, no. 3 (August 1, 2004): 642–48. https://doi.org/10.1182/blood-2003-12-4264.
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  - Rizzieri, David A., Gregory J. Sand, Dean McGaughey, Joseph O. Moore, Carlos DeCastro, Nelson J. Chao, James J. Vredenburgh, et al. “Low-dose weekly paclitaxel for recurrent or refractory aggressive non-Hodgkin lymphoma.” Cancer 100, no. 11 (June 1, 2004): 2408–14. https://doi.org/10.1002/cncr.20245.
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  - Snyder, Matthew J., Timothy T. Stenzel, Patrick J. Buckley, Anand S. Lagoo, David A. Rizzieri, Cristina Gasparetto, James J. Vredenburgh, Nelson J. Chao, and Jerald Z. Gong. “Posttransplant lymphoproliferative disorder following nonmyeloablative allogeneic stem cell transplantation.” Am J Surg Pathol 28, no. 6 (June 2004): 794–800. https://doi.org/10.1097/01.pas.0000126052.88174.f.
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  - Rizzieri, David A., Jeffrey L. Johnson, Donna Niedzwiecki, Edward J. Lee, James W. Vardiman, Bayard L. Powell, Maurice Barcos, et al. “Intensive chemotherapy with and without cranial radiation for Burkitt leukemia and lymphoma: final results of Cancer and Leukemia Group B Study 9251.” Cancer 100, no. 7 (April 1, 2004): 1438–48. https://doi.org/10.1002/cncr.20143.
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  - Goggins, Timothy F., and David R. Rizzieri. “Nonmyeloablative allogeneic stem cell transplantation using alternative donors.” Cancer Control : Journal of the Moffitt Cancer Center 11, no. 2 (March 2004): 86–96. https://doi.org/10.1177/107327480401100215.
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  - Rizzieri, D. A., S. Weitman, and D. M. Vaughn. “An EBV-positive lymphoproliferative disorder after therapy with alemtuzumab.” New England Journal of Medicine 349, no. 26 (December 25, 2003): 2571–72.
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  - Ibom, Valerie K., Robert G. Prosnitz, Jerald Z. Gong, Joseph O. Moore, Carlos M. DeCastro, Leonard R. Prosnitz, David A. Rizzieri, and Jon P. Gockerman. “Rituximab in lymphocyte predominance Hodgkin's disease: a case series.” Clin Lymphoma 4, no. 2 (September 2003): 115–18. https://doi.org/10.3816/clm.2003.n.021.
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  - Talbot, Jeffrey, David A. Rizzieri, Carlos M. DeCastro, Joseph O. Moore, Patrick Buckley, Rhonda Laney, Diane Stevenson, Heather Brumbaugh, and Jon P. Gockerman. “High-dose cyclophosphamide and etoposide for patients with refractory acute myeloid leukemia: a case series.” Am J Hematol 73, no. 4 (August 2003): 295–96. https://doi.org/10.1002/ajh.10362.
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  - Gong, Jerald Z., Timothy T. Stenzel, Ellen R. Bennett, Anand S. Lagoo, Cherie H. Dunphy, Joseph O. Moore, David A. Rizzieri, James H. Tepperberg, Peter Papenhausen, and Patrick J. Buckley. “Burkitt lymphoma arising in organ transplant recipients: a clinicopathologic study of five cases.” Am J Surg Pathol 27, no. 6 (June 2003): 818–27. https://doi.org/10.1097/00000478-200306000-00014.
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  - Rizzieri, David A., Jeffrey T. Talbot, Gwynn D. Long, James J. Vredenburgh, Christina Gasparetto, Clayton S. Smith, Michael O. Colvin, et al. “4-hydroperoxycyclophosphamide--purged peripheral blood stem cells for autologous transplantation in patients with acute myeloid leukemia.” Biol Blood Marrow Transplant 9, no. 3 (March 2003): 183–88. https://doi.org/10.1053/bbmt.2003.50011.
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  - Rizzieri, David A., Valerie K. Ibom, Joseph O. Moore, Carlos M. DeCastro, Gary L. Rosner, David J. Adams, Traci Foster, et al. “Phase I evaluation of prolonged-infusion gemcitabine with fludarabine for relapsed or refractory acute myelogenous leukemia.” Clin Cancer Res 9, no. 2 (February 2003): 663–68.
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  - Morse, Michael A., David Rizzieri, Timothy T. Stenzel, Amy C. Hobeika, James J. Vredenburgh, Nelson J. Chao, Timothy M. Clay, Paul J. Mosca, and H Kim Lyerly. “Dendritic cell recovery following nonmyeloablative allogeneic stem cell transplants.” J Hematother Stem Cell Res 11, no. 4 (August 2002): 659–68. https://doi.org/10.1089/15258160260194802.
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  - Bass, Adam J., Jon P. Gockerman, Eve Hammett, Carlos M. DeCastro, David J. Adams, Gary L. Rosner, Nancy Payne, et al. “Phase I evaluation of prolonged-infusion gemcitabine with irinotecan for relapsed or refractory leukemia or lymphoma.” J Clin Oncol 20, no. 13 (July 1, 2002): 2995–3000. https://doi.org/10.1200/JCO.2002.08.166.
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  - McCune, Steven L., Jon P. Gockerman, Joseph O. Moore, Carlos M. Decastro, Adam J. Bass, Nelson J. Chao, Gwynn D. Long, et al. “Alemtuzumab in relapsed or refractory chronic lymphocytic leukemia and prolymphocytic leukemia.” Leuk Lymphoma 43, no. 5 (May 2002): 1007–11. https://doi.org/10.1080/10428190290021597.
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  - Gasparetto, Cristina, Maura Gasparetto, Michael Morse, Barbara Rooney, James J. Vredenburgh, Gwynn D. Long, David A. Rizzieri, Jennifer Loftis, Nelson J. Chao, and Clay Smith. “Mobilization of dendritic cells from patients with breast cancer into peripheral blood stem cell leukapheresis samples using Flt-3-Ligand and G-CSF or GM-CSF.” Cytokine 18, no. 1 (April 7, 2002): 8–19. https://doi.org/10.1006/cyto.2002.1009.
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  - Chao, N. J., D. A. Rizzieri, G. D. Long, J. J. Vredenburgh, C. Gasparetto, A. Morris, and P. Davis. “Allogeneic engraftment of mismatched unrelated cord blood following a non-myeloablative preparative regimen.” Leukemia 16, no. 3 (March 1, 2002): 407–407.
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  - Bass, Adam J., Jerald Gong, Ramona Nelson, and David A. Rizzieri. “CD52 expression in mantle cell lymphoma.” Leuk Lymphoma 43, no. 2 (February 2002): 339–42. https://doi.org/10.1080/10428190290006125.
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  - Rizzieri, David A., Adam J. Bass, Gary L. Rosner, Jon P. Gockerman, Carlos M. DeCastro, William P. Petros, David J. Adams, et al. “Phase I evaluation of prolonged-infusion gemcitabine with mitoxantrone for relapsed or refractory acute leukemia.” J Clin Oncol 20, no. 3 (February 1, 2002): 674–79. https://doi.org/10.1200/JCO.2002.20.3.674.
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  - Chao, Nelson J., Cong X. Liu, Barbara Rooney, Benny J. Chen, Gwynn D. Long, James J. Vredenburgh, Ashley Morris, Cristina Gasparetto, and David A. Rizzieri. “Nonmyeloablative regimen preserves "niches" allowing for peripheral expansion of donor T-cells.” Biol Blood Marrow Transplant 8, no. 5 (2002): 249–56. https://doi.org/10.1053/bbmt.2002.v8.pm12064361.
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  - Stuart, Monic J., William P. Peters, Gloria Broadwater, Atif Hussein, Maureen Ross, Lawrence B. Marks, Rodney J. Folz, et al. “High-dose chemotherapy and hematopoietic support for patients with high-risk primary breast cancer and involvement of 4 to 9 lymph nodes.” Biol Blood Marrow Transplant 8, no. 12 (2002): 666–73. https://doi.org/10.1053/bbmt.2002.v8.abbmt080666.
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  - Rizzieri, D. A., G. D. Long, J. J. Vredenburgh, C. Gasparetto, A. Morris, T. T. Stenzel, P. Davis, and N. J. Chao. “Successful allogeneic engraftment of mismatched unrelated cord blood following a nonmyeloablative preparative regimen.” Blood 98, no. 12 (December 1, 2001): 3486–88. https://doi.org/10.1182/blood.v98.12.3486.
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  - Bass, A., J. O. Moore, C. DeCastro, J. P. Gockerman, G. Rosner, N. Payne, T. Foster, et al. “Prolonged infusion gemcitabine in combination with CPT-11 for relapsed or refractory hematologic malignancies.” Blood 98, no. 11 (November 16, 2001): 209B-209B.
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  - Gandy, K. L., N. J. Chao, C. Gasparetto, G. D. Long, N. L. Reinsmoen, and D. A. Rizzieri. “PRA reduction after sublethal preconditioning and hematopoietic reconstitution with Campath-1-treated mobilized peripheral blood.” Blood 98, no. 11 (November 16, 2001): 315B-315B.
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  - Guzman, M. L., S. J. Neering, C. Swiderski, B. Grimes, D. S. Howard, D. A. Rizzieri, and C. T. Jordan. “Unique molecular characteristics of primitive human AML cells permit apoptosis to be specifically induced in leukemic but not normal stem cells.” Blood 98, no. 11 (November 16, 2001): 93A-93A.
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  - Klein, A. K., M. B. Qumsiyeh, N. Hayes, G. D. Long, J. J. Vredenburgh, D. A. Rizzieri, C. Gasparetto, and N. J. Chao. “Translocations of the MLL gene can be detected in an increased proportion of mononuclear cells collected after etoposide priming in patients subsequently developing secondary acute leukemia.” Blood 98, no. 11 (November 16, 2001): 401A-402A.
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  - Lagoo, A. S., J. Z. Gong, D. A. Rizzieri, T. T. Stenzel, N. J. Chao, and P. J. Buckley. “Molecular evidence of engraftment in bone marrow after nonmyeloablative allogeneic stem cell transplant (NMASCT) is an unreliable indicator of residual/recurrent disease in the marrow.” Blood 98, no. 11 (November 16, 2001): 185A-185A.
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  - McCune, S. L., J. P. Gockerman, J. O. Moore, C. M. deCastro, A. J. Bass, N. J. Chao, G. D. Long, et al. “Alemtuzumab (Campath) in relapsed or refractory CLL or PLL.” Blood 98, no. 11 (November 16, 2001): 290B-291B.
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  - Rizzieri, D. A., C. DeCastro, J. P. Gockerman, D. Niedzwiecki, J. J. Vredenburgh, C. Gasparetto, G. Long, et al. “Low dose, weekly, paclitaxel as salvage therapy for non-Hodgkins lymphoma (NHL).” Blood 98, no. 11 (November 16, 2001): 246B-246B.
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  - Rizzieri, D. A., G. Akabani, R. E. Coleman, M. R. Zalutsky, D. Niedzwiecki, N. Payne, C. Wikstrand, and D. D. Bigner. “Radiolabeled anti-tenascin antibody for refractory non-Hodgkins lymphoma (NHL).” Blood 98, no. 11 (November 16, 2001): 247B-247B.
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  - Rizzieri, D. A., G. D. Long, J. J. Vredenburgh, C. Gasparetto, A. Morris, D. Niedzwiecki, M. Lassiter, et al. “Durable engraftment of mismatched unrelated cord blood following a non-myeloablative preparative regimen for adults.” Blood 98, no. 11 (November 16, 2001): 185A-185A.
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  - Rizzieri, D. A., G. D. Long, J. J. Vredenburgh, C. Gasparetto, A. Morris, M. Lassiter, J. Loftis, et al. “Non-myeloablative allogeneic transplantation using T depleted matched sibling peripheral blood stem cells.” Blood 98, no. 11 (November 16, 2001): 420A-421A.
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  - Rizzieri, D. A., G. D. Long, J. J. Vredenburgh, C. Gasparetto, A. Morris, M. Lassiter, J. Loftis, et al. “Non-myeloablative transplantation using CAMPATH 1H for T depletion of mismatched, related donor peripheral blood stem cells.” Blood 98, no. 11 (November 16, 2001): 669A-669A.
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  - Rizzieri, D. A., J. P. Gockerman, J. O. Moore, C. DeCastro, G. D. Long, J. J. Vredenburgh, D. Niedzwiecki, et al. “Dose dense, high intensity therapy for mantle cell lymphoma.” Blood 98, no. 11 (November 16, 2001): 681A-682A.
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  - Rizzieri, D. A., V. Ibom, C. DeCastro, J. O. Moore, N. Payne, D. Adams, D. J. Adams, et al. “Phase I trial of prolonged infusion gemcitabine with fludarabine for relapsed/refractory acute leukemia.” Blood 98, no. 11 (November 16, 2001): 220B-221B.
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  - Wadleigh, M., D. Niedzwiecki, P. Davis, N. Payne, F. Sen, K. P. Mann, A. Proia, D. Hollis, and D. A. Rizzieri. “Increased microvessel density in non-Hodgkin's lymphoma (NHL) is localized to the site of disease changes in accordance with disease response.” Blood 98, no. 11 (November 16, 2001): 236B-236B.
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  - Guzman, M. L., S. J. Neering, D. Upchurch, B. Grimes, D. S. Howard, D. A. Rizzieri, S. M. Luger, and C. T. Jordan. “Nuclear factor-kappaB is constitutively activated in primitive human acute myelogenous leukemia cells.” Blood 98, no. 8 (October 15, 2001): 2301–7. https://doi.org/10.1182/blood.v98.8.2301.
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  - McCune, S. L., J. P. Gockerman, and D. A. Rizzieri. “Monoclonal antibody therapy in the treatment of non-Hodgkin lymphoma.” Jama 286, no. 10 (September 12, 2001): 1149–52. https://doi.org/10.1001/jama.286.10.1149.
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  - Laughlin, M. J., J. Barker, B. Bambach, O. N. Koc, D. A. Rizzieri, J. E. Wagner, S. L. Gerson, et al. “Hematopoietic engraftment and survival in adult recipients of umbilical-cord blood from unrelated donors.” N Engl J Med 344, no. 24 (June 14, 2001): 1815–22. https://doi.org/10.1056/NEJM200106143442402.
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  - Guzman, M. L., D. Upchurch, B. Grimes, D. S. Howard, D. A. Rizzieri, S. M. Luger, G. L. Phillips, and C. T. Jordan. “Expression of tumor-suppressor genes interferon regulatory factor 1 and death-associated protein kinase in primitive acute myelogenous leukemia cells.” Blood 97, no. 7 (April 1, 2001): 2177–79. https://doi.org/10.1182/blood.v97.7.2177.
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  - Gong, J. Z., A. S. Lagoo, D. A. Rizzieri, T. T. Stenzel, N. J. Chao, and P. J. Buckley. “Serial morphologic changes in the bone arrow after non-myeloablative allogenic "mini-allogenic" stem cell transplant (NMASCT): correlation with engraftment.” Laboratory Investigation 81, no. 1 (January 1, 2001): 164A-164A.
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  - Gong, J. Z., A. S. Lagoo, D. A. Rizzieri, T. T. Stenzel, N. J. Chao, and P. J. Buckley. “Serial morphologic changes in the bone marrow after nonmyeloablative allogenic "mini-allogenic" stem cell transplant (NMASCT): correlation with engraftment.” Modern Pathology 14, no. 1 (January 1, 2001): 164A-164A.
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  - McGaughey, D. S., D. A. Nikcevich, G. D. Long, J. J. Vredenburgh, D. Rizzieri, C. A. Smith, G. Broadwater, et al. “Inhaled steroids as prophylaxis for delayed pulmonary toxicity syndrome in breast cancer patients undergoing high-dose chemotherapy and autologous stem cell transplantation.” Biol Blood Marrow Transplant 7, no. 5 (2001): 274–78. https://doi.org/10.1053/bbmt.2001.v7.pm11400949.
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  - Rizzieri, D. A., J. P. Gockerman, C. M. Decastro, S. Lilly, and T. Foster. “Phase i trial of continuously infused gemcitabine with cpt-11 for refractory hematologic malignancies.” Blood 96, no. 11 PART II (December 1, 2000).
  - Guzman, H. L., D. Upchurch, B. Grimes, D. S. Howard, G. L. Phillips, D. A. Rizzieri, S. M. Luger, and C. T. Jordan. “Induction of apoptosis in primitive human AML cells using the proteasome inhibitor MG-132 and/or sodium salicylate.” Blood 96, no. 11 (November 16, 2000): 80A-80A.
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  - Guzman, M. L., D. Upchurch, B. Grimes, D. S. Howard, G. L. Phillips, D. A. Rizzieri, S. M. Luger, and C. T. Jordan. “Expression of tumor suppressor genes IRF-1 and DAP-kinase in primitive AML cells.” Blood 96, no. 11 (November 16, 2000): 696A-696A.
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  - Laughlin, M. J., J. Barker, B. Bambach, O. N. Koc, D. A. Rizzieri, J. E. Wagner, S. L. Gerson, et al. “Hematopoietic engraftment and survival after unrelated donor umbilical cord blood (UCB) transplantation in adult recipients.” Blood 96, no. 11 (November 16, 2000): 587A-+.
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  - Rizzieri, D. A., G. D. Long, C. Gasparetto, C. S. Smith, J. J. Vredenburgh, A. K. Morris, W. P. Petros, et al. “Phase I trial of escalting doses of 4-hydroxycyclophosphamide (4HC) purged autologous peripheral blood progenitor cells (PBPC) for leukemia.” Blood 96, no. 11 (November 16, 2000): 385A-385A.
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  - Rizzieri, D. A., G. D. Long, J. J. Vredenburgh, C. Gasparetto, C. S. Smith, A. K. Morris, W. P. Petros, et al. “Chimerism mediated immunotherapy using Campath T cell depleted peripheral blood progenitor cells (PBPC) with nonablative therapy provides reliable, durable allogeneic engraftment.” Blood 96, no. 11 (November 16, 2000): 521A-521A.
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  - Rizzieri, D. A., J. P. Gockerman, C. M. DeCastro, W. P. Petros, S. Lilly, P. H. Davis, T. Foster, et al. “Phase I trial of continuously infused gemcitabine with mitoxantrone for high risk or relapsed acute leukemia.” Blood 96, no. 11 (November 16, 2000): 326A-326A.
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  - Rizzieri, D. A., J. P. Gockerman, C. M. Decastro, S. Lilly, T. Foster, D. Adams, and J. O. Moore. “Phase I trial of continuously infused gemcitabine with CPT-11 for refractory hematologic malignancies.” Blood 96, no. 11 (November 16, 2000): 216B-216B.
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  - Elconin, J. H., K. B. Roberts, D. A. Rizzieri, C. Vermont, R. W. Clough, C. Kim, R. K. Dodge, and L. R. Prosnitz. “Radiation dose selection in Hodgkin's disease patients with large mediastinal adenopathy treated with combined modality therapy.” Int J Radiat Oncol Biol Phys 48, no. 4 (November 1, 2000): 1097–1105. https://doi.org/10.1016/s0360-3016(00)00695-7.
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  - Jordan, C. T., D. Upchurch, S. J. Szilvassy, M. L. Guzman, D. S. Howard, A. L. Pettigrew, T. Meyerrose, et al. “The interleukin-3 receptor alpha chain is a unique marker for human acute myelogenous leukemia stem cells.” Leukemia 14, no. 10 (October 2000): 1777–84. https://doi.org/10.1038/sj.leu.2401903.
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  - Jordan, C. T., D. A. Rizzieri, D. Upchurch, B. Grimes, and G. L. Phillips. “The interleukin-3 receptor alpha chain is highly expressed on primitive acute myelogenous leukemia cells.” Blood 94, no. 10 (November 15, 1999): 67A-67A.
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  - Jordan, C. T., G. L. Phillips, D. A. Rizzieri, S. M. Luger, B. Grimes, and D. Upchurch. “Cell cycle analyses and apoptosis in primitive leukemic and normal cells.” Blood 94, no. 10 (November 15, 1999): 687A-687A.
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  - Howard, D. S., D. A. Rizzierri, B. Grimes, D. Upchurch, G. L. Phillips, A. K. Stewart, J. R. Yannelli, and C. T. Jordan. “Genetic manipulation of primitive leukemic and normal hematopoietic cells using a novel method of adenovirus-mediated gene transfer.” Leukemia 13, no. 10 (October 1999): 1608–16. https://doi.org/10.1038/sj.leu.2401541.
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  - Rizzieri, D. A., J. J. Vredenburgh, R. Jones, M. Ross, E. J. Shpall, A. Hussein, G. Broadwater, et al. “Prognostic and predictive factors for patients with metastatic breast cancer undergoing aggressive induction therapy followed by high-dose chemotherapy with autologous stem-cell support.” J Clin Oncol 17, no. 10 (October 1999): 3064–74. https://doi.org/10.1200/JCO.1999.17.10.3064.
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  - Rizzieri, D. A., J. J. Vredenburgh, N. J. Chao, G. Broadwater, D. Berry, and W. P. Peters. “Long term disease free survival for patients with metastatic breast cancer undergoing aggressive induction therapy followed by high dose therapy with hematopoietic support.” Blood 92, no. 10 (November 15, 1998): 323A-323A.
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  - Rizzieri, D. A., J. J. Vredenburgh, N. J. Chao, G. Broadwater, D. Berry, and W. P. Peters. “Prognostic factors for patients with metastatic breast cancer undergoing aggressive induction therapy followed by high dose therapy with hematopoietic support.” Blood 92, no. 10 (November 15, 1998): 462A-463A.
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  - Laughlin, M. J., D. A. Rizzieri, C. A. Smith, J. O. Moore, S. Lilly, D. McGaughey, P. Martin, et al. “Hematologic engraftment and reconstitution of immune function post unrelated placental cord blood transplant in an adult with acute lymphocytic leukemia.” Leuk Res 22, no. 3 (March 1998): 215–19. https://doi.org/10.1016/s0145-2126(97)00171-9.
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  - Laughlin, M. J., D. S. McGaughey, J. R. Crews, N. J. Chao, D. Rizzieri, M. Ross, J. Gockerman, et al. “Secondary myelodysplasia and acute leukemia in breast cancer patients after autologous bone marrow transplant.” J Clin Oncol 16, no. 3 (March 1998): 1008–12. https://doi.org/10.1200/JCO.1998.16.3.1008.
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  - Kurtzberg, J., M. J. Laughlin, C. A. Smith, D. A. Rizzieri, J. J. Vredenburgh, M. E. Lassiter, M. L. Affronti, et al. “Hematopoietic recovery in adult recipients following unrelated umbilical cord blood (UCB) transplantation.” Blood 90, no. 10 (November 15, 1997): 480–480.
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  - Rizzieri, D. A., and N. J. Chao. “Treatment of non-Hodgkin's lymphoma with high-dose therapy and hematopoietic stem cell support.” Curr Opin Oncol 9, no. 5 (September 1997): 420–27. https://doi.org/10.1097/00001622-199709050-00005.
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  - Rizzieri, D. A., J. Liu, D. Miralles, and S. T. Traweek. “Kaposi's-sarcoma-associated herpesvirus is detected in peripheral blood mononuclear cells of HIV-infected homosexuals more often than in heterosexuals.” Cancer J Sci Am 3, no. 3 (May 1997): 153–56.
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  - Rizzieri, David A. “Thrombocytosis Associated with Low-Molecular-Weight Heparin.” Annals of Internal Medicine 126, no. 9 (May 1, 1997): 742–742. https://doi.org/10.7326/0003-4819-126-9-199705010-00025.
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  - Williams, E. “Thrombocytosis associated with low-molecular-weight heparin.” Ann Intern Med 126, no. 9 (May 1, 1997): 742–43. https://doi.org/10.7326/0003-4819-126-9-199705010-00024.
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  - Rizzieri, D. A., J. Liu, S. T. Traweek, and G. D. Miralles. “Clearance of HHV-8 from peripheral blood mononuclear cells with a protease inhibitor.” Lancet 349, no. 9054 (March 15, 1997): 775–76. https://doi.org/10.1016/S0140-6736(05)60200-0.
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  - Rizzieri, D. A., J. Liu, D. Miralles, and S. T. Traweek. “Increased prevalence of Kaposi's sarcoma-associated herpesvirus in peripheral blood mononuclear cells of HIV-infected homosexuals.” Blood 88, no. 10 (November 15, 1996): 1992–1992.
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  - Rizzieri, D. A., W. M. Wong, and J. P. Gockerman. “Thrombocytosis associated with low-molecular-weight heparin.” Ann Intern Med 125, no. 2 (July 15, 1996): 157. https://doi.org/10.7326/0003-4819-125-2-199607150-00031.
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  - Rizzieri, D. A., C. M. DeCastro, K. P. Mann, and J. O. Moore. “T cell lymphoblastic leukemia with mediastinal mass and c-kit expression.” Blood 86, no. 10 (November 15, 1995): 3095–3095.
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  - Rizzieri, D. A. “Rhabdomyolysis after correction of hyponatremia due to psychogenic polydipsia.” Mayo Clin Proc 70, no. 5 (May 1995): 473–76. https://doi.org/10.4065/70.5.473.
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  - Rizzieri, D. A. “Causes of Rhabdomyolysis: In response.” Mayo Clinic Proceedings 70, no. 12 (January 1, 1995): 1225. https://doi.org/10.4065/70.12.1225-b.
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- Book Sections
  - Koh, L. P., D. A. Rizzieri, and N. J. Chao. “Hematopoietic stem cell transplantation across genetic barriers using a nonmyeloablative conditioning regimen.” In Bone Marrow Transplantation Across Major Genetic Barriers, 1–492, 2010. https://doi.org/10.1057/9789814271271_0006.
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- Conference Papers
  - Atallah, Ehab L., Johnnie J. Orozco, Michael Craig, Moshe Yair Levy, Laura E. Finn, Sharif S. Khan, Alexander E. Perl, et al. “A Phase 2 Study of Actinium-225 (225Ac)-Lintuzumab in Older Patients with Untreated Acute Myeloid Leukemia (AML) - Interim Analysis of 1.5 µci/Kg/Dose.” In Blood, 132:1457–1457. American Society of Hematology, 2018. https://doi.org/10.1182/blood-2018-99-111951.
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  - Cook, Rachel J., Tamara Moyo, Jane L. Liesveld, David A. Rizzieri, Eytan M. Stein, Stephane De Botton, Gail J. Roboz, et al. “Early Results from a Biomarker-Directed Phase 2 Trial of Sy-1425 in Combination with Azacitidine or Daratumumab in Non-APL Acute Myeloid Leukemia (AML) and Myelodysplastic Syndrome (MDS).” In Blood, 132:2735–2735. American Society of Hematology, 2018. https://doi.org/10.1182/blood-2018-99-111285.
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  - Jacobs, Kenneth, Cedric Viero, John Godwin, Jan Baughman, Jichao Sun, Kang Ying, John Muth, et al. “Management of Cytokine Release Syndrome in AML Patients Treated with Flotetuzumab, a CD123 x CD3 Bispecific Dart® Molecule for T-Cell Redirected Therapy.” In Blood, 132:2738–2738. American Society of Hematology, 2018. https://doi.org/10.1182/blood-2018-99-112615.
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  - Pemmaraju, Naveen, Andrew A. Lane, Kendra L. Sweet, Anthony S. Stein, Sumithira Vasu, William Blum, David A. Rizzieri, et al. “Results of Pivotal Phase 2 Clinical Trial of Tagraxofusp (SL-401) in Patients with Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN).” In Blood, 132:765–765. American Society of Hematology, 2018. https://doi.org/10.1182/blood-2018-99-118966.
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  - Sorror, Mohamed L., Barry E. Storer, Aaron T. Gerds, Bruno C. Medeiros, Paul J. Shami, John P. Galvin, Kehinde U. Adekola, et al. “Limitations to Receiving Allogeneic Hematopoietic Cell Transplantation for Treatment of Acute Myeloid Leukemia: A Large Multi-Center Prospective Longitudinal Observational Study.” In Blood, 132:1388–1388. American Society of Hematology, 2018. https://doi.org/10.1182/blood-2018-99-112672.
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  - Sorror, Mohamed L., Barry E. Storer, Aaron T. Gerds, Bruno C. Medeiros, Paul J. Shami, John P. Galvin, Kehinde U. Adekola, et al. “Survival Differences Among Patients (pts) with Acute Myeloid Leukemia (AML) Treated with Allogeneic Hematopoietic Cell Transplantation (HCT) Versus Non-HCT Therapies: A Large Real-Time Multi-Center Prospective Longitudinal Observational Study.” In Blood, 132:207–207. American Society of Hematology, 2018. https://doi.org/10.1182/blood-2018-99-113094.
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  - Uy, Geoffrey L., Michael P. Rettig, Norbert Vey, John Godwin, Matthew C. Foster, David A. Rizzieri, Martha L. Arellano, et al. “Phase 1 Cohort Expansion of Flotetuzumab, a CD123×CD3 Bispecific Dart® Protein in Patients with Relapsed/Refractory Acute Myeloid Leukemia (AML).” In Blood, 132:764–764. American Society of Hematology, 2018. https://doi.org/10.1182/blood-2018-99-117085.
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  - Ying, Zhitao, Li Long, Hong Liu, Yuqin Song, David A. Rizzieri, Bijan Nejadnik, Jun Zhu, and Cheng Liu. “ET190L1-ArtemisTM T Cell Therapy Results in Durable Disease Remissions with No Cytokine Release Syndrome or Neurotoxicity in Patients with Relapsed and Refractory B-Cell Lymphoma.” In Blood, 132:1689–1689. American Society of Hematology, 2018. https://doi.org/10.1182/blood-2018-99-113163.
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  - Cerdena, Sebastian, Melissa C. Mackey, Maragatha Kuchibhatla, David A. Rizzieri, and Meredith T. Moorman. “Evaluation of Residual Disease Positivity Rates in Adult Acute Lymphoblastic Leukemia Patients Treated with Asparaginase Versus Non-Asparaginase Containing Regimens.” In Blood, Vol. 130. AMER SOC HEMATOLOGY, 2017.
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  - Jurcic, Joseph G., Azra Raza, George Vlad, Eytan M. Stein, Mikhail Roshal, Dale L. Bixby, Daniel F. Boyer, et al. “Early Results from a Biomarker-Directed Phase 2 Trial of Sy-1425 in Acute Myeloid Leukemia (AML) and Myelodysplastic Syndrome (MDS) Demonstrate DHRS3 Induction and Myeloid Differentiation Following Sy-1425 Treatment.” In Blood, Vol. 130. AMER SOC HEMATOLOGY, 2017.
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  - Sung, Anthony D., Carlos M. de Castro, Thomas W. LeBlanc, Gwynn D. Long, Donna B. Adams, Danielle M. Brander, Sandeep Dave, et al. “Clinical Outcomes of Microtransplantation for Older Adults with Acute Myeloid Leukemia.” In Blood, Vol. 130. AMER SOC HEMATOLOGY, 2017.
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  - Anand, Sarah, Samantha Thomas, Kelly Corbet, Cristina Gasparetto, Gwynn D. Long, Richard Lopez, Ashley K. Morris, et al. “Adult Umbilical Cord Blood Transplantation Using Myeloablative Thiotepa, Total Body Irradiation, and Fludarabine Conditioning.” In Biol Blood Marrow Transplant, 23:1949–54, 2017. https://doi.org/10.1016/j.bbmt.2017.06.027.
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  - Anand, Sarah, Samantha Thomas, Kelly Corbet, Cristina Gasparetto, Richard Lopez, Gwynn D. Long, Ashley K. Morris, et al. “Adult Umbilical Cord Blood Transplantation Using Myeloablative Total Body Irradiation, Fludarabine, and Thiotepa Conditioning.” In Blood, 128:3395–3395. American Society of Hematology, 2016. https://doi.org/10.1182/blood.v128.22.3395.3395.
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  - Daver, Naval, Hagop M. Kantarjian, Gail J. Roboz, Patricia L. Kropf, Karen W. L. Yee, Casey L. O’Connell, Elizabeth A. Griffiths, et al. “Long Term Survival and Clinical Complete Responses of Various Prognostic Subgroups in 103 Relapsed/Refractory Acute Myeloid Leukemia (r/r AML) Patients Treated with Guadecitabine (SGI-110) in Phase 2 Studies.” In Blood, 128:904–904. American Society of Hematology, 2016. https://doi.org/10.1182/blood.v128.22.904.904.
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  - Garcia-Manero, Guillermo, Megan Othus, John M. Pagel, Jerald P. Radich, Min Fang, David A. Rizzieri, Guido Marcucci, et al. “SWOG S1203: A Randomized Phase III Study of Standard Cytarabine Plus Daunorubicin (7+3) Therapy Versus Idarubicin with High Dose Cytarabine (IA) with or without Vorinostat (IA+V) in Younger Patients with Previously Untreated Acute Myeloid Leukemia (AML).” In Blood, 128:901–901. American Society of Hematology, 2016. https://doi.org/10.1182/blood.v128.22.901.901.
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  - Lane, Andrew A., Kendra L. Sweet, Eunice S. Wang, William B. Donnellan, Roland B. Walter, Anthony S. Stein, David A. Rizzieri, et al. “Results from Ongoing Phase 2 Trial of SL-401 As Consolidation Therapy in Patients with Acute Myeloid Leukemia (AML) in Remission with High Relapse Risk Including Minimal Residual Disease (MRD).” In Blood, 128:215–215. American Society of Hematology, 2016. https://doi.org/10.1182/blood.v128.22.215.215.
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  - Pagel, John M., Megan Othus, Guillermo Garcia-Manero, Min Fang, Jerald P. Radich, David A. Rizzieri, Guido Marcucci, et al. “Feasibility of Allogeneic Hematopoietic Cell Transplantation Among High-Risk AML Patients in First Complete Remission: Results of the Transplant Objective from the SWOG (S1203) Randomized Phase III Study of Induction Therapy Using Standard 7+3 Therapy or Idarubicin with High-Dose Cytarabine (IA) Versus IA Plus Vorinostat.” In Blood, 128:1166–1166. American Society of Hematology, 2016. https://doi.org/10.1182/blood.v128.22.1166.1166.
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  - Pemmaraju, Naveen, Andrew A. Lane, Kendra L. Sweet, Anthony S. Stein, Sumithira Vasu, William Blum, David A. Rizzieri, et al. “Results from Phase 2 Trial Ongoing Expansion Stage of SL-401 in Patients with Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN).” In Blood, 128:342–342. American Society of Hematology, 2016. https://doi.org/10.1182/blood.v128.22.342.342.
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  - Poe, Jonathan C., Wei Jia, Hsuan Su, Zhiguo Li, Frances T. Hakim, Steven Z. Pavletic, Jeremy J. Rose, et al. “All-Trans Retinoic Acid (ATRA) Targets IRF4 Deficient, NOTCH2-Activated B Cells from Chronic Gvhd Patients.” In Blood, 128:669–669. American Society of Hematology, 2016. https://doi.org/10.1182/blood.v128.22.669.669.
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  - Giles, Francis, Steven J. Freedman, Alan Xiao, Gautant Borthakur, Guillermo Garcia-Manero, William Wierda, Steven M. Kornblau, Susan O’Brien, Donald A. Bergstrom, and David A. Rizzieri. “MK-0457, a novel multikinase inhibitor, has activity in refractory AML, including transformed JAK2 positive myeloproliferative disease (MPD), and in Philadelphia-positive ALL.” In Blood, 108:556A-556A, 2006.
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  - Rizzieri, David A., William Tse, Khuda D. Khan, Anjali Advani, Jon Donze, Verena Karsten, Robert B. Geller, and Stanton L. Gerson. “A Phase I Study of Cloretazine® and Temozolomide in Patients with Hematologic Malignancies.” In Blood, 108:1971–1971. American Society of Hematology, 2006. https://doi.org/10.1182/blood.v108.11.1971.1971.
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  - Frankel, A. E., M. A. Weir, P. D. Hall, D. E. Hogge, and D. A. Rizzieri. “Diptheria toxin-interleukin 3 fusion protein therapy of patients with elderly or relapsed/refractory acute myeloid leukemia (AML).” In Journal of Clinical Oncology, 24:354S-354S, 2006.
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  - Prasad, V. K., D. -. F. Chen, N. L. Reinsmoen, G. Broadwater, N. J. Chao, and D. A. Rizzieri. “Impact of donor KIR genotype and recipient HLA ligand incompatibility on relapse related mortality and acute graft versus host disease in high-risk patients undergoing haploidentical non-myeloablative peripheral blood stem cell transplants: Differences between lymphoid and myeloid malignancies.” In Biology of Blood and Marrow Transplantation, 12:15–15. Elsevier BV, 2006. https://doi.org/10.1016/j.bbmt.2005.11.050.
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  - Byrne, B. J., J. H. Antin, E. P. Alyea, N. J. Choa, and D. A. Rizzieri. “Efficacy of performing a second non-myeloablative allogenic stem cell transplant.” In Blood, 106:1020A-1020A, 2005.
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  - Gasparetto, C., G. P. Keogh, J. P. Gockerman, M. Horwitz, J. O. Moore, C. DeCastro, L. Diehl, P. Davis, N. Chao, and D. A. Rizzieri. “A prospective study of bortezomib in combination with melphalan and prednisone for patients with previously untreated multiple myeloma.” In Blood, 106:379B-379B. AMER SOC HEMATOLOGY, 2005.
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  - Misra, Debashish, Joseph O. Moore, Jon P. Gockerman, Louis Diehl, Carlos de Castro, Yiping Yang, Cristina Gasparetto, et al. “Phase I Study of Gemcitabine, Fludarabine and Mitoxantrone for Relapsed or Refractory Leukemia.” In Blood, 106:4623–4623. American Society of Hematology, 2005. https://doi.org/10.1182/blood.v106.11.4623.4623.
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  - Rizzieri, D. A., E. Feldman, J. O. Moore, G. J. Roboz, J. F. DiPersio, N. Gabrail, W. Stock, et al. “A phase 2 clinical trial of AP23573, an mTOR inhibitor, In patients with relapsed or refractory hematologic malignancies.” In Blood, 106:835A-836A. AMER SOC HEMATOLOGY, 2005.
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  - Rizzieri, D. A., L. P. Koh, G. D. Long, C. Gasparetto, K. M. Sullivan, M. Horwitz, J. Chute, et al. “Partially HLA matched, non-myeloablative allogeneic transplantation.” In Blood, 106:812A-812A. AMER SOC HEMATOLOGY, 2005.
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  - Rizzieri, David A., Liang Piu Koh, Gwynn D. Long, Cristina Gasparetto, Jerald Z. Gong, Anand S. Lagoo, Donna Niedzwiecki, et al. “Outcome and Immune Reconstitution Following T Cell Depleted Nonmyeloablative Allogeneic Transplantation Using Matched Donors.” In Blood, 106:2036–2036. American Society of Hematology, 2005. https://doi.org/10.1182/blood.v106.11.2036.2036.
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  - Wanko, S. O., J. P. Gockerman, J. O. Moore, C. de Castro, L. Diehl, R. Pronitz, C. Gasparetto, et al. “Multimodal dose dense therapy for mantle cell lymphoma.” In Blood, 106:463B-463B. AMER SOC HEMATOLOGY, 2005.
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  - Chen, D. F., V. K. Prasad, G. Broadwater, D. A. Rizzieri, N. J. Chao, and N. L. Reinsmoen. “Impact of donor KIR genotype and recipient HLA ligand incompatibility on relapse-related mortality in high-risk patients undergoing haploidentical non-myeloablative peripheral blood stem cell transplants: Differences between lymphoid and myelloid malignanc.” In Tissue Antigens, 66:376–376. BLACKWELL PUBLISHING, 2005.
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  - Sebastian, S., C. W. Rehder, A. S. Lagoo, J. Z. Gong, P. J. Buckley, D. A. Rizzieri, and B. K. Goodman. “An unusual 4-way translocation resulting in a rare BCR-ABL fusion transcript (e13a3) and cytogenetic evolution in chronic myeloid leukemia (CML).” In Journal of Molecular Diagnostics, 7:661–661. AMER SOC INVESTIGATIVE PATHOLOGY, INC, 2005.
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  - Grinblatt, David L., Jeffrey Johnson, Donna Niedzwicki, David A. Rizzieri, Nancy Bartlett, and Bruce D. Cheson. “Phase II Study of Thalidomide in Escalating Doses for Follicular (F-NHL) and Small Lymphocytic Lymphoma (Sll): CALGB Study 50002.” In Blood, 104:3284–3284. American Society of Hematology, 2004. https://doi.org/10.1182/blood.v104.11.3284.3284.
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  - Koh, Liang-Piu, Jon P. Gockerman, Joseph O. Moore, Carlos DeCastro, Gwynn D. Long, Cristina Gasparetto, Donna Niedzwiecki, et al. “Dose Dense, High Intensity Induction Therapy Followed by Early High Dose Chemotherapy (HDT) and Autologous Hematopoietic Stem Cell Transplantation(AHSCT) for Mantle Cell Lymphoma (MCL).” In Blood, 104:913–913. American Society of Hematology, 2004. https://doi.org/10.1182/blood.v104.11.913.913.
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  - Misra, D., A. Frankel, P. Hall, T. F. Liu, J. Black, J. O. Moore, C. de Castro, et al. “The use of DT388-IL3 fusion protein in patients with refractory acute myeloid leukemia(AML).” In Blood, 104:212B-212B. AMER SOC HEMATOLOGY, 2004.
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  - Rao, A. V., D. A. Rizzieri, J. O. Moore, C. Decastro, A. P. Abernethy, M. Jordan, P. Davis, E. Edmonds, and J. P. Gockerman. “Dose dense, high intensity therapy in newly diagnosed elderly patients with acute myeloid leukemia using gemtuzumab ozogamicin (Mylotarg (TM)) and high dose cytarabine (HiDAC).” In Blood, 104:212B-213B. AMER SOC HEMATOLOGY, 2004.
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  - Wanko, Sam O., Jon P. Gocherman, Joseph O. Moore, Carlos Decastro, Robert Prosnitz, Cristina Gasparetto, John Chute, et al. “Multimodal Dose Dense Therapy for Mantle Cell Lymphoma.” In Blood, 104:1163–1163. American Society of Hematology, 2004. https://doi.org/10.1182/blood.v104.11.1163.1163.
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  - Gong, J. Z., D. Y. Trembath, B. K. Goodman, D. Quigley, S. Sebastian, D. A. Rizzieri, J. P. Gockerman, A. S. Lagoo, and P. J. Buckley. “Detection of genomic losses and gains in myelodysplastic syndrome and acute myeloid leukemia by array comparative genomic hybridization.” In Journal of Molecular Diagnostics, 6:420–420. AMER SOC INVESTIGATIVE PATHOLOGY, INC, 2004.
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  - Akabani, G., D. A. Rizzieri, M. R. Zalutsky, R. E. Coleman, S. D. Metzler, J. E. Bowsher, B. Toaso, et al. “Phase I trial study of [131]I-labeled chimeric 81C6 mAb for the treatment of patients with non-Hodgkin's lymphoma.” In European Journal of Nuclear Medicine and Molecular Imaging, 31:S222–S222. SPRINGER, 2004.
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  - Castro, C. M. de, H. Uronis, J. O. Moore, J. P. Gockerman, D. A. Rizzieri, and N. J. Chao. “Successful treatment of pure red cell aplasia (PRCA) with alemtuzumab (CAMPATH-1H).” In Blood, 102:19B-19B. AMER SOC HEMATOLOGY, 2003.
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  - Gasparetto, C., N. J. Chao, M. E. Horwitz, J. O. Moore, C. DeCastro, J. Gockerman, K. Sullivan, et al. “Pharmacokinetics of subcutaneous alemtuzumab in a patient with myeloma.” In Blood, 102:385B-385B. AMER SOC HEMATOLOGY, 2003.
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  - Goggins, T. F., D. A. Rizzieri, R. Prosnitz, C. Gasparetto, G. Long, M. E. Horwitz, K. Sullivan, et al. “One day preparative regimen for allogeneic non-myeloablative stem cell transplantation (NMSCT) using 3-5/6 HLA matched related donors.” In Blood, 102:476B-477B. AMER SOC HEMATOLOGY, 2003.
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  - Rizzieri, D. A., G. Akabani, M. Zalutsky, R. E. Coleman, B. Toaso, E. Anderson, A. Lagoo, et al. “Phase I trial with pharmocokinetics, dosimetry, toxicity and response of anti-stromal therapy using I-131 labeled chimeric anti-tenascin therapy for lymphoma.” In Blood, 102:635A-636A. AMER SOC HEMATOLOGY, 2003.
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  - Rizzieri, D. A., G. J. Sand, D. McGaughey, J. Moore, C. DeCastro, N. Chao, J. Vredenburgh, et al. “Low-dose weekly paclitaxel for relapsed or refractory aggressive non-Hodgkins lymphoma.” In Blood, 102:641A-641A. AMER SOC HEMATOLOGY, 2003.
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  - Rizzieri, D. A., L. P. Koh, G. D. Long, A. S. Lagoo, C. Gasparatto, J. J. Vredenburgh, P. J. Buckley, et al. “Clinical outcome and immune reconstitution following alemtuzumab T cell depleted nonmyeloablative allogeneic immunotherapy from HLA matched siblings.” In Blood, 102:238A-239A. AMER SOC HEMATOLOGY, 2003.
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  - Rizzieri, D. A., L. P. Koh, G. D. Long, C. Gasparetto, J. J. Vredenburgh, P. J. Buckley, G. Gong, et al. “Clinical outcome and immune reconstitution following alemtuzumab T cell depleted nonmyeloablative allogeneic immunotherapy using HLA mis-matched (3-5/6) related hematopoietic stem cells.” In Blood, 102:482A-482A. AMER SOC HEMATOLOGY, 2003.
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  - Sand, G. J., J. O. Moore, C. DeCastro, J. P. Gockerman, B. Peterson, P. J. Buckley, B. Toaso, D. Adams, and D. A. Rizzieri. “Phase one evaluation of gemcitabine, fludarabine, and mitoxantrone for relapsed or refractory leukemia.” In Blood, 102:250B-250B. AMER SOC HEMATOLOGY, 2003.
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  - Talbot, J. T., V. K. Ibom, R. Barrier, D. Niedzwieki, C. M. Castro, J. O. Moore, P. J. Buckley, et al. “Dose-intense cyclophosphamide and etoposide for patients with refractory or high risk non-Hogdkin's lymphoma.” In Blood, 102:287B-287B. AMER SOC HEMATOLOGY, 2003.
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  - Snyder, M. J., T. T. Stenzel, A. S. Lagoo, D. A. Rizzieri, N. Chao, P. J. Buckley, and J. Z. Gong. “Post-transplant lymphoproliferative disorder following non-myeloablative allogeneic stem cell transplantation.” In Laboratory Investigation, 83:253A-253A. LIPPINCOTT WILLIAMS & WILKINS, 2003.
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  - Snyder, M. J., T. T. Stenzel, A. S. Lagoo, D. A. Rizzieri, N. Chao, P. J. Buckley, and J. Z. Gong. “Post-transplant lymphoproliferative disorder following non-myeloablative allogeneic stem cell transplantation.” In Modern Pathology, 16:253A-253A. LIPPINCOTT WILLIAMS & WILKINS, 2003.
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  - Foran, J., M. Wetzler, H. M. Karitarjian, S. Faderl, N. Abramson, D. A. Rizzieri, A. Craig, J. Weiss, and D. Douer. “A phase II, open-label study of CLOPAREX(TM) in adult patients with refractory or relapsed acute myelogenous leukemia.” In Blood, 100:271B-271B, 2002.
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  - Gandy, K. L., N. J. Chao, G. D. Long, V. Sartain, H. F. Seigler, and D. A. Rizzieri. “Donor-specific tolerance after hematopoietic reconstitution with Campath-1H treated mobilized peripheral blood cells in a sublethal preconditioning regimen.” In Blood, 100:410A-410A. AMER SOC HEMATOLOGY, 2002.
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  - Isola, L. M., J. N. Chao, S. Weinberg, S. M. Fruchtman, G. Atweh, S. McCune, M. J. Telen, et al. “Donor chimerism after T-Cell depleted (TCD)-Non-Myeloablative allogeneic SCT (NST) in hemoglobinopathies.” In Blood, 100:401B-402B. AMER SOC HEMATOLOGY, 2002.
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  - Johnston, L. J., J. S. Shizuru, K. E. Stockerl-Goldstein, M. J. Stuart, C. Gasparetto, G. D. Long, D. A. Rizzieri, et al. “GLAT (Copaxone) for treatment of steroid-refractory acute graft versus host disease.” In Blood, 100:421A-421A, 2002.
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  - Koh, L. P., D. A. Rizzieri, G. D. Long, J. J. Vredenburgh, C. Gaparetto, A. Morris, B. Water-Picks, et al. “Campath-1H, T cell depleted nonmyeloablative peripheral blood stem cell transplantation from 3-6/6 HLA matched family members.” In Blood, 100:638A-638A. AMER SOC HEMATOLOGY, 2002.
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  - Lonial, S., D. A. Rizzieri, L. P. Koh, M. Jones, A. A. Langston, I. Redei, G. D. Long, et al. “Three methods of T-cell depletion of HPCT products: Analysis of CD34+ cell and lymphocyte purity and recovery.” In Blood, 100:835A-836A. AMER SOC HEMATOLOGY, 2002.
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  - Rai, K. R., M. J. Keating, S. Coutre, D. A. Rizzieri, and Campath Study Grp. “Patients with refractory B-CLL and T-PLL treated with alemtuzumab (Campath (R)) on a compassionate basis. A report on efficacy and safety of CAM 511 trial.” In Blood, 100:802A-802A, 2002.
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  - Morse, M. A., D. Rizzieri, A. C. Hobeika, N. Chao, and H. Kirn Lyerly. “Dendritic cell (DC) reconstitution after nonmyeloablative allogeneic stem cell transplants.” In Blood, Vol. 96, 2000.

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