David R. Sherwood

Professor of Biology

Biology

david.sherwood@duke.edu

https://orcid.org/0000-0002-4448-6917

Duke Box 90338, Durham, NC 27708-1000

Box 90338, Department of Biology, Durham, NC 27708

More About This Person

At a Glance

Credentials
1. Education

Academic Experience

Global Scholarship

Keywords

Research
1. Selected Grants
2. External Relationships

Scholarly Works

Teaching & Mentoring
1. Recent Courses

Recognition
1. Academic Honors
2. News Items

Professional Activities
1. Presentations, Performances & Exhibitions
2. Service to the Profession

Scholarly Works - Conferences

Specialized mitochondria fuel cell Invasion through basement membranes

Conference MOLECULAR BIOLOGY OF THE CELL · January 1, 2024 Link to item Cite

Fibulin-1 supports basement membrane stretching during ovulation in C. elegans

Conference MOLECULAR BIOLOGY OF THE CELL · January 1, 2024 Link to item Cite

Chemical-induced toxicity is ameliorated by swimming exercise in caenorhabditis elegans

Conference Drug Metabolism and Pharmacokinetics · January 2019 Full text Cite

The role of lipid metabolism in anchor cell invasion in C.elegans

Conference MOLECULAR BIOLOGY OF THE CELL · December 15, 2018 Link to item Cite

Humanized, transgenic worms to study the role of mitochondrial CYP2E1 in toxicant-induced mitochondrial dysfunction and neurodegeneration

Conference Drug Metabolism and Pharmacokinetics · January 2018 Full text Cite

WASP and WAVE activate the Arp2/3 complex for actin-based force production during basement membrane invasion.

Conference MOLECULAR BIOLOGY OF THE CELL · January 1, 2017 Link to item Cite

Type IV Collagen stabilizes the connection of juxtaposed tissues at the B-LINK complex.

Conference MOLECULAR BIOLOGY OF THE CELL · January 1, 2016 Link to item Cite

Rapid exocytosis of an endolysosome-derived membrane domain forms a polarized invasive protrusion that clears basement membrane during cell invasion.

Conference MOLECULAR BIOLOGY OF THE CELL · January 1, 2015 Link to item Cite

Visualizing and elucidating the regulation of type IV collagen assembly in developing basement membranes

Conference MOLECULAR BIOLOGY OF THE CELL · January 1, 2015 Link to item Cite

Cell invasion through basement membrane requires multiple GTPases and is initiated by CDC-42 directed invadopodia formation

Conference MOLECULAR BIOLOGY OF THE CELL · December 1, 2014 Link to item Cite

Cell cycle arrest is required for cell invasive behavior.

Conference MOLECULAR BIOLOGY OF THE CELL · December 1, 2014 Link to item Cite

Investigating the B-LINK: an adhesion system that links neighboring basement membranes.

Conference MOLECULAR BIOLOGY OF THE CELL · December 1, 2014 Link to item Cite

Identification of two novel insulin- and hormone-regulated nutritional checkpoints in C. elegans development

Conference INTEGRATIVE AND COMPARATIVE BIOLOGY · January 1, 2014 Link to item Cite

Targeted cell cycle arrest halts basement membrane gap expansion during nematode uterine-vulval attachment

Conference INTEGRATIVE AND COMPARATIVE BIOLOGY · January 1, 2014 Link to item Cite

The evolution of anchor cell invasion during rhabditid nematode vulval development

Conference INTEGRATIVE AND COMPARATIVE BIOLOGY · April 1, 2013 Link to item Cite

Patterning of cell cycle arrest during formation of the nematode uterine-vulval connection

Conference INTEGRATIVE AND COMPARATIVE BIOLOGY · April 1, 2013 Link to item Cite

MMP-Independent Mechanisms of Basement Membrane Breaching In Vivo

Conference MOLECULAR BIOLOGY OF THE CELL · January 1, 2013 Link to item Cite

The receptor DCC mediates oscillatory, self-organizing polarity to orient towards netrin

Conference MOLECULAR BIOLOGY OF THE CELL · January 1, 2013 Link to item Cite

Characterizing the role of CDC-42 in cell invasion through basement membrane

Conference MOLECULAR BIOLOGY OF THE CELL · January 1, 2013 Link to item Cite

MMP-Independent Mechanisms of Basement Membrane Breaching In Vivo

Conference MOLECULAR BIOLOGY OF THE CELL · 2013 Link to item Cite

In situ imaging in C. elegans reveals developmental and subcellular regulation of microtubule dynamics

Conference MOLECULAR BIOLOGY OF THE CELL · January 1, 2013 Link to item Cite

Anchor cell invasion across the Nematoda: a highly conserved cell biological process required for establishing the uterine-vulval connection

Conference INTEGRATIVE AND COMPARATIVE BIOLOGY · April 1, 2012 Link to item Cite

Exploring microtubule dynamics in vivo and its role in tissue biogenesis

Conference MOLECULAR BIOLOGY OF THE CELL · January 1, 2012 Link to item Cite

Cell Cycle Arrest is Required For Cell Invasion Through Basement Membranes

Conference MOLECULAR BIOLOGY OF THE CELL · January 1, 2012 Link to item Cite

HIM-4/Hemicentin Links the Uterine and Vulval Basement Membranes during Anchor Cell Invasion in C. elegans

Conference MOLECULAR BIOLOGY OF THE CELL · January 1, 2011 Link to item Cite

Imaging the Cell-Basement Membrane Interface during Anchor Cell Invasion in C. elegans

Conference MOLECULAR BIOLOGY OF THE CELL · January 1, 2011 Link to item Cite

In vivo imaging of microtubule dynamics throughout tissue biogenesis and cell differentiation

Conference MOLECULAR BIOLOGY OF THE CELL · January 1, 2011 Link to item Cite

Specification of mesoderm and endoderm during cleavage in sea urchin embryos

Conference REGULATORY PROCESSES IN DEVELOPMENT · January 1, 2000 Link to item Cite

Notch signaling positions germ-layer boundaries in the sea urchin embryo.

Conference DEVELOPMENTAL BIOLOGY · June 1, 1998 Link to item Cite

Notch signaling positions germ-layers in the sea urchin embryo

Conference MOLECULAR BIOLOGY OF THE CELL · November 1, 1997 Link to item Cite

Axial specification in the sea urchin embryo.

Conference DEVELOPMENTAL BIOLOGY · June 15, 1997 Link to item Cite

A novel shift in subcellular distribution of notch defines the presumptive endoderm-mesoderm boundary in the sea urchin embryo

Conference MOLECULAR BIOLOGY OF THE CELL · December 1, 1996 Link to item Cite

A sea urchin hedgehog homolog.

Conference DEVELOPMENTAL BIOLOGY · May 1, 1996 Link to item Cite

A HOMOLOG OF NOTCH IS EXPRESSED IN THE VEGETAL PLATE, DEVELOPING GUT AND ECTODERM OF THE SEA-URCHIN, LYTECHINUS-VARIEGATUS

Conference DEVELOPMENTAL BIOLOGY · August 1, 1995 Link to item Cite

THE IDENTIFICATION, CLONING AND EXPRESSION PATTERN OF A NOTCH HOMOLOG IN THE SEA-URCHIN, LYTECHINUS-VARIEGATUS

Conference DEVELOPMENTAL BIOLOGY · June 1, 1994 Link to item Cite