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Dawn Elizabeth Bowles

Assistant Professor in Surgery
Surgery, Surgical Sciences
Box 2642 Med Ctr, Durham, NC 27710
421B MSRB, Durham, NC 27710

Current Appointments & Affiliations


Assistant Professor in Surgery · 2021 - Present Surgery, Surgical Sciences, Surgery

Recent Publications


UBR1 Promotes Sex-Dependent ACE2 Ubiquitination in Hypertension.

Journal Article Hypertension · January 2025 BACKGROUND: Ang-II (angiotensin II) impairs the function of the antihypertensive enzyme ACE2 (angiotensin-converting enzyme 2) by promoting its internalization, ubiquitination, and degradation, thus contributing to hypertension. However, few ACE2 ubiquitin ... Full text Link to item Cite

Current approaches to optimize the donor heart for transplantation.

Journal Article J Heart Lung Transplant · December 25, 2024 Heart transplantation remains a critical therapy for patients with end-stage heart failure, offering incremental survival and improved quality of life. One of the key components behind the success of heart transplantation is the condition and preservation ... Full text Link to item Cite

TRIM35 Monoubiquitinates H2B in Cardiac Cells, Implications for Heart Failure.

Journal Article Circ Res · July 5, 2024 BACKGROUND: The tumor suppressor and proapoptotic transcription factor P53 is induced (and activated) in several forms of heart failure, including cardiotoxicity and dilated cardiomyopathy; however, the precise mechanism that coordinates its induction with ... Full text Link to item Cite
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Recent Grants


Tolerance to Allogeneic Hearts via Implantation of Cultured Donor Thymus

ResearchCo Investigator · Awarded by National Institutes of Health · 2025 - 2028

Stimulating Access to Research in Residency (StARR) - NHLBI

Inst. Training Prgm or CMEPreceptor · Awarded by National Heart, Lung, and Blood Institute · 2018 - 2028

Genetic engineering of kidney allografts by ex vivo perfusion delivery of adeno-associated viral vectors

ResearchCo Investigator · Awarded by National Institute of Allergy and Infectious Diseases · 2022 - 2027

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Education, Training & Certifications


Louisiana State University · 1999 Ph.D.