Scholars@Duke

• Background
• 

  Education, Training, & Certifications

  • Ph.D., Louisiana State University 1999
• 

  Duke Appointment History

  • Assistant Professor of Surgery, Surgery, Surgical Sciences, Surgery 2006 - 2012
  • Assistant Research Professor in Surgery, Surgery, Cardiovascular and Thoracic Surgery, Surgery 2005 - 2006
  • Instructor, Temporary in the Department of Surgery, Surgery, Cardiovascular and Thoracic Surgery, Surgery 2004 - 2005
• Research
• 

  Selected Grants

  • Stratification of heart failure patients for cardiac recovery upon cardiac unloading by left Ventricular assist device therapy awarded by Humanitas Mirasole S.p.a 2020 - 2023
  • Duke Resident Physician-Scientist Program- NHLBI awarded by National Institutes of Health 2018 - 2022
  • Gene Therapy Countermeasure for Detrimental Effects of Space Radiation awarded by Baylor College of Medicine 2019 - 2021
  • Evolving Inside the Box awarded by North Carolina Biotechnology Center 2018 - 2020
  • Awakening Endogenous Retroviruses with the Space Environment awarded by National Aeronautics and Space Administration 2019 - 2020
  • Enzyvant Monkey Study awarded by Enzyvant 2019 - 2020
  • Proteomic Signatures of Space Radiation Induced Cardiovascular Degeneration awarded by National Aeronautics and Space Administration 2016 - 2020
  • Heart Cap Implants awarded by North Carolina State University 2019 - 2020
  • Development of a lightweight, portable, pneumatic drive unit for long-term counterpulsation support awarded by NuPulseCV, Inc. 2019
  • Utilization of Two Heartmate III Pumps as a Total Artificial Heart Replacement awarded by St. Jude Medical Inc. 2017 - 2019
  • Expanding the capabilities and the utilization of the Duke Human Heart Repository awarded by North Carolina Biotechnology Center 2017 - 2019
  • Cadaver Implant Studies of PABP awarded by 3R Life Sciences Taiwan Ltd. 2018 - 2019
  • Protection from cardiac ischemic injury through use of KP544 awarded by Krenitsky Pharmaceuticals Inc. 2017 - 2018
  • A Prospective Pilot Study to Examine the Involvement of apoE Gene Variants in Intracranial Hemorrhage in LVAD Patients awarded by HeartWare, Inc 2015 - 2016
  • E3 Ligases and Deubiquitinases in GPCR Down Regulation awarded by National Institutes of Health 2005 - 2016
  • Heart Risk Model awarded by National Aeronautics and Space Administration 2013 - 2016
  • Expanding the Donor Pool for Heart Transplantation awarded by National Institutes of Health 2012 - 2014
  • Proteomic Profiling of Human Heart Tissue Exposed to Microgravity awarded by National Aeronautics and Space Administration 2012 - 2013
  • Peripheral endothelial and muscle cell pathology in cardiovascular disease awarded by National Institutes of Health 2010 - 2013
  • Autologous EPC lining to improve biocompatibility of circulatory assist devices awarded by National Institutes of Health 2009 - 2012
  • PTEN Gene Therapy for Vein Graft Disease awarded by National Institutes of Health 2009 - 2012
  • Myocardial Gene Transfer during Cardiac Surgery in Swine awarded by National Institutes of Health 2003 - 2008
• 

  External Relationships

  • AskBio
  • Caripae, LLC
• Publications & Artistic Works
• 

  Selected Publications

  • Academic Articles

    • Brown, Zachary D., Muath Bishawi, Jun-Neng Roan, Franklin Lee, Adam Nevo, Michael Watson, and Dawn E. Bowles. “The use of an inexpensive processing aid device (the Mouse PAD) to facilitate rodent tissue banking.” Biotechniques 69, no. 1 (July 2020): 364–68. https://doi.org/10.2144/btn-2019-0069.
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    • Stevenson, Mark D., Chandrika Canugovi, Aleksandr E. Vendrov, Takayuki Hayami, Dawn E. Bowles, Karl-Heinz Krause, Nageswara R. Madamanchi, and Marschall S. Runge. “NADPH Oxidase 4 Regulates Inflammation in Ischemic Heart Failure: Role of Soluble Epoxide Hydrolase.” Antioxid Redox Signal 31, no. 1 (July 1, 2019): 39–58. https://doi.org/10.1089/ars.2018.7548.
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    • Bishawi, Muath, Jun-Neng Roan, Carmelo A. Milano, Mani A. Daneshmand, Jacob N. Schroder, Yuting Chiang, Franklin H. Lee, et al. “A normothermic ex vivo organ perfusion delivery method for cardiac transplantation gene therapy.” Sci Rep 9, no. 1 (May 29, 2019): 8029. https://doi.org/10.1038/s41598-019-43737-y.
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    • Ren, Linda, Robert A. Holzknecht, Zoie E. Holzknecht, Sanet H. Kotzé, Dawn E. Bowles, Shu S. Lin, Erin A. McKenney, and William Parker. “A mole rat's gut microbiota suggests selective influence of diet on microbial niche space and evolution.” Exp Biol Med (Maywood) 244, no. 6 (April 2019): 471–83. https://doi.org/10.1177/1535370219828703.
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    • Beak, Ju Youn, Hong Soon Kang, Wei Huang, Page H. Myers, Dawn E. Bowles, Anton M. Jetten, and Brian C. Jensen. “The nuclear receptor RORα protects against angiotensin II-induced cardiac hypertrophy and heart failure.” Am J Physiol Heart Circ Physiol 316, no. 1 (January 1, 2019): H186–200. https://doi.org/10.1152/ajpheart.00531.2018.
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    • Bishawi, Muath, Jeremy Joseph, Chetan Patel, Jacob Schroder, Mani Daneshmand, Dawn Bowles, Joseph Rogers, and Carmelo Milano. “Risk factors for stroke on left ventricular assist devices.” J Card Surg 33, no. 6 (June 2018): 348–52. https://doi.org/10.1111/jocs.13718.
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    • Bishawi, Muath, Jun-Neng Roan, Jordan Richards, Zachary Brown, Laura Blue, Mani A. Daneshmand, Jacob N. Schroder, Dawn E. Bowles, and Carmelo A. Milano. “Use of Two Intracorporeal Ventricular Assist Devices As a Total Artificial Heart.” J Vis Exp, no. 135 (May 11, 2018). https://doi.org/10.3791/55961.
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    • Hayashi, Hiroki, Douglas T. Hess, Rongli Zhang, Keiki Sugi, Huiyun Gao, Bea L. Tan, Dawn E. Bowles, et al. “S-Nitrosylation of β-Arrestins Biases Receptor Signaling and Confers Ligand Independence.” Mol Cell 70, no. 3 (May 3, 2018): 473-487.e6. https://doi.org/10.1016/j.molcel.2018.03.034.
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    • Jean-Charles, Pierre-Yves, Samuel Mon-Wei Yu, Dennis Abraham, Reddy Peera Kommaddi, Lan Mao, Ryan T. Strachan, Zhu-Shan Zhang, et al. “Mdm2 regulates cardiac contractility by inhibiting GRK2-mediated desensitization of β-adrenergic receptor signaling.” Jci Insight 2, no. 17 (September 7, 2017). https://doi.org/10.1172/jci.insight.95998.
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    • Santacruz, Lucia, Antonio Jose Luis Arciniegas, Marcus Darrabie, Jose G. Mantilla, Rebecca M. Baron, Dawn E. Bowles, Rajashree Mishra, and Danny O. Jacobs. “Hypoxia decreases creatine uptake in cardiomyocytes, while creatine supplementation enhances HIF activation.” Physiol Rep 5, no. 16 (August 2017). https://doi.org/10.14814/phy2.13382.
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    • Guo, Hongtao, Zhiyong Mi, Dawn E. Bowles, Syamal D. Bhattacharya, and Paul C. Kuo. “Osteopontin and protein kinase C regulate PDLIM2 activation and STAT1 ubiquitination in LPS-treated murine macrophages.” J Biol Chem 292, no. 3 (January 20, 2017): 1142. https://doi.org/10.1074/jbc.A110.161869.
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    • Jensen, Brian C., Scott J. Bultman, Darcy Holley, Wei Tang, Gustaaf de Ridder, Salvatore Pizzo, Dawn Bowles, and Monte S. Willis. “Upregulation of autophagy genes and the unfolded protein response in human heart failure.” Int J Clin Exp Med 10, no. 1 (2017): 1051–58.
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    • Feger, Bryan J., J Will Thompson, Laura G. Dubois, Reddy P. Kommaddi, Matthew W. Foster, Rajashree Mishra, Sudha K. Shenoy, et al. “Microgravity induces proteomics changes involved in endoplasmic reticulum stress and mitochondrial protection.” Sci Rep 6 (September 27, 2016): 34091. https://doi.org/10.1038/srep34091.
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    • Schechter, Matthew A., Michael J. Watson, Bryan J. Feger, Kevin W. Southerland, Rajashree Mishra, Louis R. Dibernardo, Maragatha Kuchibhatla, et al. “Elevated Cardiac Troponin I in Preservation Solution Is Associated With Primary Graft Dysfunction.” J Card Fail 22, no. 2 (February 2016): 158–62. https://doi.org/10.1016/j.cardfail.2015.08.339.
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    • Ahmad, Tariq, Jacob P. Kelly, Robert W. McGarrah, Anne S. Hellkamp, Mona Fiuzat, Jeffrey M. Testani, Teresa S. Wang, et al. “Prognostic Implications of Long-Chain Acylcarnitines in Heart Failure and Reversibility With Mechanical Circulatory Support.” J Am Coll Cardiol 67, no. 3 (January 26, 2016): 291–99. https://doi.org/10.1016/j.jacc.2015.10.079.
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    • Gaval-Cruz, Meriem, Richard B. Goertz, Daniel J. Puttick, Dawn E. Bowles, Rebecca C. Meyer, Randy A. Hall, Daijin Ko, Carlos A. Paladini, and David Weinshenker. “Chronic loss of noradrenergic tone produces β-arrestin2-mediated cocaine hypersensitivity and alters cellular D2 responses in the nucleus accumbens.” Addict Biol 21, no. 1 (January 2016): 35–48. https://doi.org/10.1111/adb.12174.
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    • Pratico, Elizabeth D., Bryan J. Feger, Michael J. Watson, Bruce A. Sullenger, Dawn E. Bowles, Carmelo A. Milano, and Smita K. Nair. “RNA-Mediated Reprogramming of Primary Adult Human Dermal Fibroblasts into c-kit(+) Cardiac Progenitor Cells.” Stem Cells Dev 24, no. 22 (November 15, 2015): 2622–33. https://doi.org/10.1089/scd.2015.0073.
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    • Schechter, Matthew A., Kevin W. Southerland, Bryan J. Feger, Dean Linder, Ayyaz A. Ali, Linda Njoroge, Carmelo A. Milano, and Dawn E. Bowles. “An isolated working heart system for large animal models.” J Vis Exp, no. 88 (June 11, 2014). https://doi.org/10.3791/51671.
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    • Schechter, Matthew A., Michael K. H. Hsieh, Linda W. Njoroge, J Will Thompson, Erik J. Soderblom, Bryan J. Feger, Constantine D. Troupes, et al. “Phosphoproteomic profiling of human myocardial tissues distinguishes ischemic from non-ischemic end stage heart failure.” Plos One 9, no. 8 (2014): e104157. https://doi.org/10.1371/journal.pone.0104157.
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    • Foster, Matthew W., J Will Thompson, Michael T. Forrester, Yonggang Sha, Timothy J. McMahon, Dawn E. Bowles, M Arthur Moseley, and Harvey E. Marshall. “Proteomic analysis of the NOS2 interactome in human airway epithelial cells.” Nitric Oxide 34 (November 1, 2013): 37–46. https://doi.org/10.1016/j.niox.2013.02.079.
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    • Southerland, Kevin W., Sarah B. Frazier, Dawn E. Bowles, Carmelo A. Milano, and Christopher D. Kontos. “Gene therapy for the prevention of vein graft disease.” Transl Res 161, no. 4 (April 2013): 321–38. https://doi.org/10.1016/j.trsl.2012.12.003.
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    • Messina, Emily L., Jeffrey Nienaber, Mani Daneshmand, Nestor Villamizar, Jude Samulski, Carmelo Milano, and Dawn E. Bowles. “Adeno-associated viral vectors based on serotype 3b use components of the fibroblast growth factor receptor signaling complex for efficient transduction.” Hum Gene Ther 23, no. 10 (October 2012): 1031–42. https://doi.org/10.1089/hum.2012.066.
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    • Li, Chengwen, Nina Diprimio, Dawn E. Bowles, Matthew L. Hirsch, Paul E. Monahan, Aravind Asokan, Joseph Rabinowitz, Mavis Agbandje-McKenna, and R Jude Samulski. “Single amino acid modification of adeno-associated virus capsid changes transduction and humoral immune profiles.” J Virol 86, no. 15 (August 2012): 7752–59. https://doi.org/10.1128/JVI.00675-12.
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    • Piacentino, Valentino, Carmelo A. Milano, Michael Bolanos, Jacob Schroder, Emily Messina, Adam S. Cockrell, Edward Jones, et al. “X-linked inhibitor of apoptosis protein-mediated attenuation of apoptosis, using a novel cardiac-enhanced adeno-associated viral vector.” Hum Gene Ther 23, no. 6 (June 2012): 635–46. https://doi.org/10.1089/hum.2011.186.
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    • Bowles, Dawn E., Scott W. J. McPhee, Chengwen Li, Steven J. Gray, Jade J. Samulski, Angelique S. Camp, Juan Li, et al. “Phase 1 gene therapy for Duchenne muscular dystrophy using a translational optimized AAV vector.” Mol Ther 20, no. 2 (February 2012): 443–55. https://doi.org/10.1038/mt.2011.237.
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    • Sun, Qi-An, Douglas T. Hess, Leonardo Nogueira, Sandro Yong, Dawn E. Bowles, Jerry Eu, Kenneth R. Laurita, Gerhard Meissner, and Jonathan S. Stamler. “Oxygen-coupled redox regulation of the skeletal muscle ryanodine receptor-Ca2+ release channel by NADPH oxidase 4.” Proc Natl Acad Sci U S A 108, no. 38 (September 20, 2011): 16098–103. https://doi.org/10.1073/pnas.1109546108.
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    • Darrabie, Marcus D., Antonio Jose Luis Arciniegas, Rajashree Mishra, Dawn E. Bowles, Danny O. Jacobs, and Lucia Santacruz. “AMPK and substrate availability regulate creatine transport in cultured cardiomyocytes.” Am J Physiol Endocrinol Metab 300, no. 5 (May 2011): E870–76. https://doi.org/10.1152/ajpendo.00554.2010.
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    • Villamizar, Nestor R., Jennifer H. Crow, Valentino Piacentino, Louis R. DiBernardo, Mani A. Daneshmand, Dawn E. Bowles, Mark A. Groh, and Carmelo A. Milano. “Reproducibility of left atrial ablation with high-intensity focused ultrasound energy in a calf model.” J Thorac Cardiovasc Surg 140, no. 6 (December 2010): 1381-7.e1. https://doi.org/10.1016/j.jtcvs.2010.08.029.
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    • Guo, Hongtao, Zhiyong Mi, Dawn E. Bowles, Syamal D. Bhattacharya, and Paul C. Kuo. “Osteopontin and protein kinase C regulate PDLIM2 activation and STAT1 ubiquitination in LPS-treated murine macrophages.” J Biol Chem 285, no. 48 (November 26, 2010): 37787–96. https://doi.org/10.1074/jbc.M110.161869.
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    • Piacentino, Valentino, Michael Bolanos, Jacob Schroder, Emily Messina, Edward Jones, Ava Krol, Nenad Bursac, et al. “X-Linked Inhibitor of Apoptosis Protein (XIAP)-Mediated Attenuation of Apoptosis Using a Novel Cardiac Enhanced Adeno-Associated Viral Vector.” Circulation 122, no. 21 (November 23, 2010).
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    • Mendell, Jerry R., Katherine Campbell, Louise Rodino-Klapac, Zarife Sahenk, Chris Shilling, Sarah Lewis, Dawn Bowles, et al. “Dystrophin immunity in Duchenne's muscular dystrophy.” N Engl J Med 363, no. 15 (October 7, 2010): 1429–37. https://doi.org/10.1056/NEJMoa1000228.
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    • Crow, Sheri, Dong Chen, Carmelo Milano, William Thomas, Lyle Joyce, Valentino Piacentino, Riti Sharma, et al. “Acquired von Willebrand syndrome in continuous-flow ventricular assist device recipients.” Ann Thorac Surg 90, no. 4 (October 2010): 1263–69. https://doi.org/10.1016/j.athoracsur.2010.04.099.
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    • Crow, Sheri, Carmelo Milano, Lyle Joyce, Dong Chen, Gowthami Arepally, Dawn Bowles, William Thomas, and Nestor Villamizar Ortiz. “Comparative analysis of von Willebrand factor profiles in pulsatile and continuous left ventricular assist device recipients.” Asaio J 56, no. 5 (September 2010): 441–45. https://doi.org/10.1097/MAT.0b013e3181e5de0a.
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    • Chen, Eefei, Mary Lou Everett, Zoie E. Holzknecht, Robert A. Holzknecht, Shu S. Lin, Dawn E. Bowles, and William Parker. “Short-lived alpha-helical intermediates in the folding of beta-sheet proteins.” Biochemistry 49, no. 26 (July 6, 2010): 5609–19. https://doi.org/10.1021/bi100288q.
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    • Lee, Sean M., Aaron Wyse, Aaron Lesher, Mary Lou Everett, Linda Lou, Zoie E. Holzknecht, John F. Whitesides, et al. “Adaptation in a mouse colony monoassociated with Escherichia coli K-12 for more than 1,000 days.” Appl Environ Microbiol 76, no. 14 (July 2010): 4655–63. https://doi.org/10.1128/AEM.00358-10.
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    • Lima, Brian, Gregory K. W. Lam, Liang Xie, Diana L. Diesen, Nestor Villamizar, Jeffrey Nienaber, Emily Messina, et al. “Endogenous S-nitrosothiols protect against myocardial injury.” Proc Natl Acad Sci U S A 106, no. 15 (April 14, 2009): 6297–6302. https://doi.org/10.1073/pnas.0901043106.
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    • Li, Chengwen, Dawn E. Bowles, Terry van Dyke, and Richard Jude Samulski. “Adeno-associated virus vectors: potential applications for cancer gene therapy.” Cancer Gene Ther 12, no. 12 (December 2005): 913–25. https://doi.org/10.1038/sj.cgt.7700876.
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    • McAvin, James C., David E. Bowles, James A. Swaby, Keith W. Blount, Jamie A. Blow, Miguel Quintana, John R. Hickman, Daniel H. Atchley, and Debra M. Niemeyer. “Identification of Aedes aegypti and its respective life stages by real-time polymerase chain reaction.” Mil Med 170, no. 12 (December 2005): 1060–65. https://doi.org/10.7205/milmed.170.12.1060.
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    • McAvin, James C., Elizabeth M. Escamilla, Jamie A. Blow, Michael J. Turell, Miguel Quintana, David E. Bowles, James A. Swaby, et al. “Rapid identification of dengue virus by reverse transcription-polymerase chain reaction using field-deployable instrumentation.” Mil Med 170, no. 12 (December 2005): 1053–59. https://doi.org/10.7205/milmed.170.12.1053.
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    • Rabinowitz, Joseph E., Dawn E. Bowles, Susan M. Faust, Julie G. Ledford, Scott E. Cunningham, and R Jude Samulski. “Cross-dressing the virion: the transcapsidation of adeno-associated virus serotypes functionally defines subgroups.” J Virol 78, no. 9 (May 2004): 4421–32. https://doi.org/10.1128/jvi.78.9.4421-4432.2004.
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    • Bowles, Dawn E., Joseph E. Rabinowitz, and R Jude Samulski. “Marker rescue of adeno-associated virus (AAV) capsid mutants: a novel approach for chimeric AAV production.” J Virol 77, no. 1 (January 2003): 423–32. https://doi.org/10.1128/jvi.77.1.423-432.2003.
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    • Bowles, D. E., S. K. Kim, and D. J. O’Callaghan. “Characterization of the trans-activation properties of equine herpesvirus 1 EICP0 protein.” J Virol 74, no. 3 (February 2000): 1200–1208. https://doi.org/10.1128/jvi.74.3.1200-1208.2000.
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    • Kim, S. K., D. E. Bowles, and D. J. O’callaghan. “The gamma2 late glycoprotein K promoter of equine herpesvirus 1 is differentially regulated by the IE and EICP0 proteins.” Virology 256, no. 2 (April 10, 1999): 173–79. https://doi.org/10.1006/viro.1999.9608.
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    • Bowles, D. E., V. R. Holden, Y. Zhao, and D. J. O’Callaghan. “The ICP0 protein of equine herpesvirus 1 is an early protein that independently transactivates expression of all classes of viral promoters.” J Virol 71, no. 7 (July 1997): 4904–14. https://doi.org/10.1128/JVI.71.7.4904-4914.1997.
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    • Campbell, Brian S., and David E. Bowles. “Human tick bite records in a United States Air Force population, 1989–1992: implications for tick-borne disease risk.” Journal of Wilderness Medicine 5, no. 4 (December 1994): 405–12. https://doi.org/10.1580/0953-9859-5.4.405.
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    • Bowles, David E., and O. H. Griffin. “Micromechanics Analysis of Space Simulated Thermal Stresses in Composites. Part I: Theory and Unidirectional Laminates.” Journal of Reinforced Plastics and Composites 10, no. 5 (September 1991): 504–21. https://doi.org/10.1177/073168449101000506.
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    • Bowles, David E., and O. H. Griffin. “Micromechanics Analysis of Space Simulated Thermal Stresses in Composites. Part II: Multidirectional Laminates and Failure Predictions.” Journal of Reinforced Plastics and Composites 10, no. 5 (September 1991): 522–39. https://doi.org/10.1177/073168449101000507.
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    • BOWLES, D. E., and D. R. TENNEY. “COMPOSITE TUBES FOR THE SPACE STATION TRUSS STRUCTURE.” Sampe Journal 23, no. 3 (May 1, 1987): 49–57.
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    • Bowles, David E., Stephen S. Tompkins, and George F. Sykes. “Electron radiation effects on the thermal expansion of graphite resin composites.” Journal of Spacecraft and Rockets 23, no. 6 (November 1986): 625–29. https://doi.org/10.2514/3.25857.
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    • SYKES, G. F., and D. E. BOWLES. “SPACE RADIATION EFFECTS ON THE DIMENSIONAL STABILITY OF A TOUGHENED EPOXY GRAPHITE COMPOSITE.” Sampe Quarterly Society for the Advancement of Material and Process Engineering 17, no. 4 (July 1, 1986): 39–45.
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    • HAGEMAIER, D. J., and D. BOWLES. “EVALUATION OF MAGNETIC PARTICLE INSPECTION OXIDES.” Materials Evaluation 37, no. 11 (January 1, 1979): 47–53.
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    • Wang, Teresa, Emily C. O’Brien, Joseph G. Rogers, Daniel L. Jacoby, Michael E. Chen, Jeffrey M. Testani, Dawn E. Bowles, et al. “Plasma Levels of MicroRNA-155 Are Upregulated with Long-Term Left Ventricular Assist Device Support.” Asaio J 63, no. 5 (n.d.): 536–41. https://doi.org/10.1097/MAT.0000000000000564.
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  • Conference Papers

    • Chiang, Y. P., M. Bishawi, C. Wang, M. J. Watson, F. H. Lee, A. Roki, A. Doty, et al. “Successful Gene Delivery to Cardiac Allograft with Adeno-Associated Viral Vector Using Ex Vivo Storage Perfusion Platform.” In The Journal of Heart and Lung Transplantation : The Official Publication of the International Society for Heart Transplantation, 39:S360–61, 2020. https://doi.org/10.1016/j.healun.2020.01.434.
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    • Bishawi, Muath, Jun-Neng Roan, Carmelo A. Milano, Mani A. Daneshmand, Jacob N. Schroder, Zachary D. Brown, Adam Nevo, et al. “Wide Spread Adenoviral Vector Delivery to a Cardiac Allograft Utilizing an Ex Vivo Perfusion Storage Strategy.” In Molecular Therapy, 26:69–69. CELL PRESS, 2018.
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    • Watson, Michael, Deborah Cholon, Samuel Perez-Tamayo, Vayun Agrawal, Yoichiro Shibata, Martina Gentzsch, and Dawn Bowles. “Cystic Fibrosis Transmembrane Conductance Regulator Is Heterologously Expressed in Human Heart.” In Faseb Journal, Vol. 32. FEDERATION AMER SOC EXP BIOL, 2018.
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    • Stevenson, Mark D., Chandrika Canugovi, Aleksandr E. Vendrov, Dawn E. Bowles, Nageswara R. Madamanchi, and Marschall S. Runge. “NADPH Oxidase 4 Contributes to Ischemic Cardiomyopathy by Activating Soluble Epoxide Hydrolase.” In Circulation, Vol. 136. LIPPINCOTT WILLIAMS & WILKINS, 2017.
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    • Jean-Charles, Pierre-Yves, Samuel Mon-Wei Yu, Lan Mao, Reddy Perra Kommadi, Zhushan Zhang, Jonathan Stiber, Dawn Bowles, et al. “Beta(1)-Adrenergic Receptor-induced Cardiac Contractility is dependent on MDM2-mediated GRK2 Turnover.” In Circulation Research, 119:E162–63. LIPPINCOTT WILLIAMS & WILKINS, 2016.
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    • Bishawi, M., J. Joseph, B. Yerokun, D. Ranney, P. Winterton, J. Schroder, M. Daneshmand, D. Bowles, J. Rogers, and C. Milano. “Incidence and Outcomes After Stroke on Rotary Flow Ventricular Assist Device Support.” In The Journal of Heart and Lung Transplantation, 35:S262–63. Elsevier BV, 2016. https://doi.org/10.1016/j.healun.2016.01.745.
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    • Schechter, M. A., K. W. Southerland, B. J. Feger, L. Njoroge, D. Linder, D. E. Bowles, and C. A. Milano. “Functional and Biochemical Assessment of Porcine Hearts After Simulated Donation After Circulatory Death.” In The Journal of Heart and Lung Transplantation, 34:S150–S150. Elsevier BV, 2015. https://doi.org/10.1016/j.healun.2015.01.403.
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    • Schechter, M. A., K. W. Southerland, M. J. Watson, B. J. Feger, R. Mishra, J. N. Schroder, L. R. Dibernardo, et al. “Cardiac Troponin I Levels in Preservation Solution Predict Primary Graft Dysfunction After Heart Transplant.” In The Journal of Heart and Lung Transplantation, 34:S268–S268. Elsevier BV, 2015. https://doi.org/10.1016/j.healun.2015.01.750.
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    • Wang, Teresa, Emily O’Brien, Marc Samsky, Joseph Rogers, Adrian Hernandez, Dawn Bowles, G Michael Felker, Chetan Patel, and Tariq Ahmad. “Effects of Left Ventricular Assist Device Support on microRNA Levels.” In Circulation, Vol. 130. LIPPINCOTT WILLIAMS & WILKINS, 2014.
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    • Ahmad, Tariq, Teresa Wang, Marc Samsky, Damian Craig, Gary M. Felker, Adrian Hernandez, Joseph Rogers, et al. “Effects of Left Ventricular Assist Device Placement on Biomarkers of Cardiovascular Stress, Fibrosis, Fluid Homeostasis, Mitochondrial Function, Metabolism, and Endothelial Dysfunction.” In Circulation, Vol. 128. LIPPINCOTT WILLIAMS & WILKINS, 2013.
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    • Foster, Matthew, J Will Thompson, Michael Forrester, Yonggang Sha, Dawn Bowles, M Arthur Moseley, and Harvey Marshall. “Quantitative proteomics of the cytokine-modulated NOS2 interactome in airway epithelial cells.” In Nitric Oxide, 27:S13–S13. Elsevier BV, 2012. https://doi.org/10.1016/j.niox.2012.04.047.
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    • Foster, M. W., Z. T. Kelleher, M. T. Forrester, D. E. Bowles, M. A. Moseley, and H. E. Marshall. “Quantitative Proteomics Of The Cytokine-Modulated Nos2 Interactome In Airway Epithelium.” In American Journal of Respiratory and Critical Care Medicine, Vol. 183. AMER THORACIC SOC, 2011.
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    • Piacentino III, P., J. W. Thompson, E. J. Soderblom, M. Foster, V. A. Burns, J. G. Rogers, C. A. Milano, M. A. Moseley, and D. E. Bowles. “Ischemic Human Heart Failure is Associated With Decreased Phosphorylation of Pyruvate Dehydrogenase and Triosephosphate Isomerase: Proteomic Evidence Supporting Carbohydrate Utilization Preference in the End-Stage Failing Ischemic Heart.” In Circulation, Vol. 122, 2010.
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    • Campbell, Katherine, Louise Rodino-Klapac, Zarife Sahenk, Chris Shilling, Sarah Lewis, Dawn Bowles, Steven Gray, et al. “Revertant muscle fibers expressing dystrophin do not tolerize the immune system in Duchenne muscular dystrophy: lessons learned from a Phase I clinical trial.” In Journal of Immunology, Vol. 184. AMER ASSOC IMMUNOLOGISTS, 2010.
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    • Mendell, Jerry, Katherine Campbell, Louise Rodino-Klapac, Zarife Sahenk, Christopher Shilling, Sarah Lewis, Dawn Bowles, et al. “Transient Expression of a Therapeutic Dystrophin Transgene in Duchenne Muscular Dystrophy Revealed by T Cell Mediated Immunity.” In Neurology, 74:A111–A111. LIPPINCOTT WILLIAMS & WILKINS, 2010.
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    • Bowles, Dawn E., Chengwen Li, Paul E. Monahan, Joseph E. Rabinowitz, Mavis McKenna, and Jude Samulski. “1064. Haute Couture Vectors: Solving Clinical Problems with Custom Designed AAV Vectors.” In Molecular Therapy, 13:S408–S408. Elsevier BV, 2006. https://doi.org/10.1016/j.ymthe.2006.08.1162.
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    • Faust, S. M., D. E. Bowles, S. E. Cunningham, J. E. Rabinowitz, and R. J. Samulski. “Universal purification of AAV serotypes 1-5 modified to contain a heparin binding epitope.” In Molecular Therapy, 9:S36–S36. ACADEMIC PRESS INC ELSEVIER SCIENCE, 2004.
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    • Grieger, J. C., J. E. Rabinowitz, D. E. Bowles, and R. J. Samulski. “Role of Vp2 in AAV packaging.” In Molecular Therapy, 9:S7–S7. ACADEMIC PRESS INC ELSEVIER SCIENCE, 2004.
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    • Rabinowitz, J. E., D. E. Bowles, S. M. Faust, J. G. Ledford, S. E. Cunningham, and R. J. Samulski. “The transcapsidation of AAV serotypes.” In Molecular Therapy, 9:S8–S8. ACADEMIC PRESS INC ELSEVIER SCIENCE, 2004.
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    • Tompkins, Stephen S., Joan G. Funk, David E. Bowles, Timothy W. Towell, and John W. Connell. “Composite materials for precision space reflector panels.” In Design of Optical Instruments. SPIE, 1992. https://doi.org/10.1117/12.138000.
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    • BOWLES, D. E., S. S. TOMPKINS, and J. G. FUNK. “RESIDUAL THERMAL-STRESSES IN COMPOSITES FOR DIMENSIONALLY STABLE SPACECRAFT APPLICATIONS.” In Proceedings of the Vii International Congress on Experimental Mechanics, Vols 1 and 2, 1211–19. SOC EXPERIMENTAL MECHANICS INC, 1992.
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    • Tompkins, Stephen S., David E. Bowles, Joan G. Funk, J. A. Lavoie, and Timothy W. Towell. “Development of composite materials for spacecraft precision-reflector panels.” In Advances in Optical Structure Systems. SPIE, 1990. https://doi.org/10.1117/12.21533.
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    • BOWLES, D. E., and O. H. GRIFFIN. “ANALYSIS OF THERMAL-STRESSES IN POLYMER MATRIX COMPOSITES.” In Tomorrows Materials : Today, Book 1 and 2, edited by G. A. ZAKRZEWSKI, D. MAZENKO, S. T. PETERS, and C. D. DEAN, 34:575–84. SOC ADVANCEMENT MATERIAL & PROCESS ENGINEERING, 1989.
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    • DERSTINE, M. S., M. J. PINDERA, and D. E. BOWLES. “EXPERIMENTAL ANALYTICAL CHARACTERIZATION OF COMPOSITE TUBES UNDER COMBINED LOADING.” In Proceedings of the 1989 Sem Spring Conference on Experimental Mechanics, 483–90. SOC EXPERIMENTAL MECHANICS INC, 1989.
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    • BOWLES, D. “X-RAY INSPECTION TECHNIQUES FOR LAMINATED GRAPHITE HONEYCOMB COMPOSITES.” In Materials Evaluation, 41:S20–S20. AMER SOC NON-DESTRUCTIVE TEST, 1983.
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