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Dawn Elizabeth Bowles

Assistant Professor in Surgery
Surgery, Surgical Sciences
Box 2642 Med Ctr, Durham, NC 27710
421B MSRB, Durham, NC 27710

Current Appointments & Affiliations


Assistant Professor in Surgery · 2021 - Present Surgery, Surgical Sciences, Surgery

Recent Publications


Current approaches to optimize the donor heart for transplantation.

Journal Article J Heart Lung Transplant · April 2025 Heart transplantation remains a critical therapy for patients with end-stage heart failure, offering incremental survival and improved quality of life. One of the key components behind the success of heart transplantation is the condition and preservation ... Full text Link to item Cite

UBR1 Promotes Sex-Dependent ACE2 Ubiquitination in Hypertension.

Journal Article Hypertension · January 2025 BACKGROUND: Ang-II (angiotensin II) impairs the function of the antihypertensive enzyme ACE2 (angiotensin-converting enzyme 2) by promoting its internalization, ubiquitination, and degradation, thus contributing to hypertension. However, few ACE2 ubiquitin ... Full text Link to item Cite

Delivery of a Muscle-Targeted Adeno-Associated Vector Via Ex Vivo Normothermic Perfusion Is Efficient, Durable, and Safe in a Preclinical Porcine Heart Transplant Model.

Journal Article Transpl Int · 2025 Normothermic ex-vivo organ perfusion (EVP) systems not only provide a physiological environment that preserves donor organ function outside the body but may also serve as platforms for ex-vivo organ modification via gene therapy. In this study, we demonstr ... Full text Link to item Cite
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Recent Grants


Tolerance to Allogeneic Hearts via Implantation of Cultured Donor Thymus

ResearchCo Investigator · Awarded by National Institutes of Health · 2025 - 2028

Stimulating Access to Research in Residency (StARR) - NHLBI

Inst. Training Prgm or CMEPreceptor · Awarded by National Heart, Lung, and Blood Institute · 2018 - 2028

Genetic engineering of kidney allografts by ex vivo perfusion delivery of adeno-associated viral vectors

ResearchCo Investigator · Awarded by National Institute of Allergy and Infectious Diseases · 2022 - 2027

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Education, Training & Certifications


Louisiana State University · 1999 Ph.D.