Scholars@Duke
Dawn Elizabeth Bowles

Dawn Elizabeth Bowles

Assistant Professor in Surgery
Surgery, Surgical Sciences
dawn.bowles@duke.edu
Box 2642 Med Ctr, Durham, NC 27710
421B MSRB, Durham, NC 27710

Scholarly Works - Conferences

Abstract Fri050: The Role of Macrophages in the Progression of Amyloid Transthyretin Cardiomyopathy

Conference Circulation Research · August 2025 Introduction: Amyloid Transthyretin Cardiomyopathy (ATTR-CM) is caused by the myocardial uptake of transthyretin (TTR), resulting in protein aggregation, cytotoxicity, and ultimately dysfunction. Meth ... Full text Cite

A porcine model of acute rejection for cardiac transplantation

Conference Frontiers in Cardiovascular Medicine · January 1, 2025 Ex vivo machine perfusion has been growing in utility for preserving donor organs prior to transplantation. This modality has tremendous potential for bioengineering and conditioning organs prior to transplantation using small molecule or advanced therapeu ... Full text Cite

Abstract 4142546: Single-Nucleus RNA Sequencing Reveals Region-Specific Cell Composition and Transcriptional Variations in Cardiac Sarcoidosis

Conference Circulation · November 12, 2024 Introduction: Sarcoidosis is a granulomatous disease of unknown cause that can affect any organ. Cardiac involvement, indicated by arrhythmias, conduction abnormalities, heart failure, and sudden card ... Full text Cite

Metabolomic profiling during ex situ normothermic perfusion before heart transplantation defines patterns of substrate utilization and correlates with markers of allograft injury.

Conference J Heart Lung Transplant · May 2024 BACKGROUND: Cardiac metabolism is altered in heart failure and ischemia-reperfusion injury states. We hypothesized that metabolomic profiling during ex situ normothermic perfusion before heart transplantation (HT) would lend insight into myocardial substra ... Full text Link to item Cite

Successful Gene Delivery to Cardiac Allograft with Adeno-Associated Viral Vector Using Ex Vivo Storage Perfusion Platform

Conference The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · April 1, 2020 PURPOSE: Cardiac gene therapy remains limited by inefficient transgene delivery with currently available methods (intravenous infusion, transcatheter coronary artery infusion, direct myocardial injection). We previously demonstrated in a porcine heterotopi ... Full text Cite

Incidence and Outcomes After Stroke on Rotary Flow Ventricular Assist Device Support

Conference The Journal of Heart and Lung Transplantation · April 2016 Full text Cite

Quantitative Proteomics Of The Cytokine-Modulated Nos2 Interactome In Airway Epithelium

Conference AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE · January 1, 2011 Link to item Cite

The transcapsidation of AAV serotypes

Conference MOLECULAR THERAPY · May 1, 2004 Link to item Cite

Role of Vp2 in AAV packaging

Conference MOLECULAR THERAPY · May 1, 2004 Link to item Cite