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Debolina Biswas

Research Associate, Senior
Pediatrics, Pulmonary and Sleep Medicine
203, Research Drive, Durham, NC 27710

Overview


ElMallah Laboratory

Current Appointments & Affiliations


Recent Publications


AAV9 gene therapy to target respiratory insufficiency in the D2.mdx mouse model of duchenne muscular dystrophy.

Journal Article Respir Physiol Neurobiol · November 14, 2025 Duchenne muscular dystrophy (DMD) is an X-linked recessive disorder caused by a deficiency of dystrophin. Dystrophin deficiency leads to progressive muscle weakness, including involvement of the respiratory muscles, ultimately resulting in respiratory fail ... Full text Link to item Cite

Progressive central cardiorespiratory rate downregulation and intensifying epilepsy lead to sudden unexpected death in epilepsy in mouse model of the most common human ATP1A3 mutation.

Journal Article Epilepsia · March 2025 OBJECTIVE: This study was undertaken to test the following hypotheses in the Atp1a3Mashl/+ mouse (which carries the most common human ATP1A3 (the major subunit of the neuronal Na+/K+-adenosine triphosphatase [ATPase]) mutation, D801N): sudden unexpected de ... Full text Link to item Cite

Respiratory pathology in the mdx/utrn -/- mouse: A murine model for Duchenne Muscular Dystrophy (DMD).

Journal Article PLoS One · 2025 Duchenne muscular dystrophy (DMD) is an X-linked devastating disease caused by a lack of dystrophin which results in progressive muscle weakness. As muscle weakness progresses, respiratory insufficiency and hypoventilation result in significant morbidity a ... Full text Link to item Cite
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Recent Grants


Alveolar injury and repair in Pompe Disease

ResearchPostdoctoral Associate · Awarded by National Institutes of Health · 2025 - 2028

Optimizing Gene Therapy for Respiratory Insufficiency in Duchenne Muscular Dystrophy

ResearchPostdoctoral Associate · Awarded by National Heart, Lung, and Blood Institute · 2024 - 2028

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External Links


ElMallah Lab