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Dennis Ko

Associate Professor in Molecular Genetics and Microbiology
Molecular Genetics and Microbiology
0049 CARL Building, Box 3053, 213 Research Drive, Durham, NC 27710


Using Pathogens to Decipher Genetic Variation Connecting Cell Biology and Disease Susceptibility
Despite improvements in public health, advancements in vaccines, and the development of many classes of antibiotics, infectious disease is still responsible for over a quarter of all deaths worldwide. However, even for the most devastating of pandemics, individuals demonstrate a large variability in the severity of infection. The long-term goal of the lab is to understand the genetic basis for differences in susceptibility to infection and related inflammatory disorders. We approach this question through a combination of experimental and computational approaches that combine high-throughput cell biology with quantitative human genetics. The identified genetic differences serve as the starting point for exploring new cell biology and human disease susceptibility genes.

Current Appointments & Affiliations

Associate Professor in Molecular Genetics and Microbiology · 2020 - Present Molecular Genetics and Microbiology, Basic Science Departments
Associate Professor of Cell Biology · 2022 - Present Cell Biology, Basic Science Departments
Associate Professor in Medicine · 2022 - Present Medicine, Clinical Science Departments
Associate of the Duke Initiative for Science & Society · 2017 - Present Duke Science & Society, Initiatives

Education, Training & Certifications

Stanford University · 2005 M.D.
Stanford University · 2003 Ph.D.