Scholars@Duke
Derek Southwell

Derek Southwell

Associate Professor of Neurosurgery
Neurosurgery
derek.southwell@duke.edu
DUMC 3807, Durham, NC 27710
DUMC 3807, 1542 Blue Zone Duke South, Durham, NC 27710

Scholarly Works - Preprints

RNA-programmable cell type monitoring and manipulation in the human cortex with CellREADR.

Preprint · May 9, 2025 Reliable and systematic access to diverse cell types is necessary for understanding the organization, function, and pathophysiology of human neural circuits. Methods for targeting human neural populations are scarce and currently center on identifying tran ... Full text Link to item Cite

Thalamo-cortical Synchrony Shapes Seizure Expression in Human Temporal Lobe Epilepsy

Preprint · 2025 AbstractIn drug-resistant temporal lobe epilepsy (DR-TLE), electrographic seizures with clinical symptoms (CS) largely determine quality of life, yet some remain silent (NCS) despite arising from the same seizure-onset zone (SOZ). While ... Full text Cite