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Domna Kotsifaki

Assistant Professor of Physics at Duke Kunshan University
DKU Faculty

Scholarly Works - Conferences


Trapping and Chemical Characterization of sub-microplastics Using Raman Optical Tweezers and Machine Learning

Conference Proceedings of SPIE the International Society for Optical Engineering · September 16, 2025 The accumulation of plastics in the environment and their fragmentation into micro- and nanoplastics represent a growing ecological and public health concern. Accurate detection and classification of these particles remain challenging due to their small si ... Full text Cite

Directed migration of liposomes using thermoplasmonic optical tweezers

Conference Optical Manipulation and Its Applications Oma 2025 in Proceedings Optica Biophotonics Congress 2025 Part of Optica Biophotonics Congress Optics in the Life Sciences · January 1, 2025 Liposomes serve as versatile platforms for drug delivery, nanocontainers, and membrane mimics. We have combined optical trapping and thermal forces in order to achieve rapid liposome migration with low laser power, with migration speeds of 1.77 µm/s for li ... Full text Cite

Biosensing applications based on metallic nanostructures

Conference Proceedings of SPIE the International Society for Optical Engineering · January 1, 2024 We designed and fabricated an array of metallic nano-aperture on a gold film to enhance the detection of immunoglobulin G (IgG) protein in the liquid environment. The plasmonic nanostructure is designed to exhibit a resonance at 762 nm. The field enhanceme ... Full text Cite

Plasmonic nanostructures for environmental monitoring and/or biological applications

Conference Proceedings of SPIE the International Society for Optical Engineering · January 1, 2023 In this work, we have identified the size of microplastics collected from Shi Lake, China, using an optical tweezer micro-Raman spectroscopy (OTMRS) system. The microplastics were classified based on their size as products of degradation of large plastic m ... Full text Cite

Manipulation, trapping, and biosensing using metamaterial devices

Conference Optical Manipulation and Its Applications Oma 2023 · January 1, 2023 We have designed and fabricated plasmonic metamaterial devices for single nanoparticle trapping and biosensing applications. We studied the ability to trap several nano-objects. Moreover, we have identified bacteria in liquid using the same designed metama ... Full text Cite

Nanoparticle positioning via metamaterial plasmonic tweezers

Conference Proceedings of SPIE the International Society for Optical Engineering · January 1, 2022 We present sequential trapping and positioning of 20 nm polystyrene particles into an array configuration by using metamaterial plasmonic tweezers. The polystyrene nanoparticles suspended into a heavy water solution were trapped on adjacent plasmonic hotsp ... Full text Cite

Detection and analysis of microplastics in the subtropical ocean of Okinawa using micro-Raman Optical Tweezers

Conference 2021 IEEE International Workshop on Metrology for the Sea Learning to Measure Sea Health Parameters Metrosea 2021 Proceedings · January 1, 2021 Plastic is a widely used material in our daily lives. Microplastic pollution has also generated worldwide concern due to its distribution in the environment, and its potential threat to human and animal health. Due to the complexity of sampling and extract ... Full text Cite

Analysis of small plastics in coastal surface water samples of Okinawa using optical tweezers-Raman spectroscopy

Conference Proceedings of SPIE the International Society for Optical Engineering · January 1, 2021 In this work, we employ an optical trapping-Raman spectroscopy technique for simultaneous characterization and monitoring of the physical and chemical properties of single small micro-plastics in a seawater environment. Through analysis of the data, we che ... Full text Cite

Raman optical tweezers for microplastic pollution identification in the surface waters of Okinawa

Conference Proceedings of SPIE the International Society for Optical Engineering · January 1, 2021 Marine plastic debris is a widely recognized environmental issue. By employing an optical micro-Raman tweezers setup, we have identified the composition of particles trapped in marine aggregates collected from the coastal surface waters around the subtropi ... Full text Cite

Giant optical forces using an array of asymmetric split-ring plasmonic nanostructures

Conference Proceedings of SPIE the International Society for Optical Engineering · January 1, 2021 We demonstrated optical trapping of 20 nm particles using a Fano-resonance-assisted plasmonic tweezers based on arrays of asymmetrical split nanoapertures on a 50-nm gold thin film. By transmission and reflection spectra measurements, the close-mode Fano-t ... Full text Cite

Multiple nanoparticle trapping with low laser intensity, using gold plasmonic array

Conference Optical Manipulation and Its Applications Proceedings Biophotonics Congress Optics in the Life Sciences Congress 2019 Boda Brain NTM Oma Omp · April 8, 2019 We used a patterned gold nanohole array for trapping multiple polystyrene nanoparticles (30 nm) at low laser intensity (0.51 mW/μm2). A high trap stiffness was achieved (0.85 fN/(nm·mW) and experimental values were in agreement with simulations. ... Cite

Trapping nanoparticles with nearfield plasmonic tweezers

Conference Optics Infobase Conference Papers · January 1, 2019 We present multiple polystyrene nanoparticle trapping at extremely low laser intensity, using a patterned gold array. High experimental trapping stiffness is obtained, in very good agreement with simulated values. ... Full text Cite

Plasmonic annular aperture arrays for nanoparticle manipulation

Conference Proceedings of SPIE the International Society for Optical Engineering · January 1, 2019 In this work, we present experimental results on the optical trapping and manipulation of micro- and nanoparticles using plasmonic tweezers based on arrays of annular nanoapertures. By increasing the inner disk size of the nanoaperture, a redshift of the r ... Full text Cite

Single-protein and single nanoparticle trapping using plasmonic nanoaperture array

Conference Proceedings of SPIE the International Society for Optical Engineering · January 1, 2019 We demonstrate optical trapping of single Cytochrome c proteins, using a plasmonic tweezers based on metallic asymmetric nano-aperture arrays. We succeed in immobilizing single proteins with very low in-trap laser intensities. This approach paves the way f ... Cite

Biophotonics for imaging and cell manipulation: Quo vadis?

Conference Proceedings of SPIE the International Society for Optical Engineering · January 1, 2017 As one of the major health problems for mankind is cancer, any development for the early detection and effective treatment of cancer is crucial to saving lives. Worldwide, the dream for the anti-cancer procedure of attack is the development of a safe and e ... Full text Cite

Enhanced optical forces in plasmonic microstructures

Conference Springer Proceedings in Physics · January 1, 2014 Micromanipulation of dielectric objects, from polystyrene spheres to living cells, is achieved when radiation pressure forces create stable trapping by highly focused laser beams through microscopes. However, the impressive history of optical trapping is s ... Full text Cite

Near infrared optical tweezers and nanosecond ablation on yeast and algae cells

Conference Proceedings of SPIE the International Society for Optical Engineering · July 22, 2013 In recent years, lasers for optical trapping and micromanipulation of microscopic particles or cells and sub cellular structures, both in vivo and in vitro, have gained remarkable interest in biomedical research and applications. Although the principles an ... Full text Cite

Micromanipulation of cells and microparticles using optical fibers

Conference Progress in Biomedical Optics and Imaging Proceedings of SPIE · August 1, 2011 Optical tweezers is a powerful tool which is used to capture and manipulate microscopic particles such as dielectric microspheres and cells. In the single optical trap the beam is strongly focused to a diffraction limited spot by a high numerical aperture ... Full text Cite

Fibers and fiber end sealing caps for Er:YAG laser ablation

Conference Proceedings of SPIE the International Society for Optical Engineering · February 23, 2011 considerable interest, in the recent years, has been allocated in the mid-infrared Er:YAG laser surgery and microsurgery. This interest has been increased after the development of optical fibers and waveguides, for safe and efficient transmission of the ∼3 ... Full text Cite

Paper surface modification by lasers

Conference Proceedings of SPIE the International Society for Optical Engineering · February 23, 2011 Lasers can provide a precious tool to conservation process due to their accuracy and the controlled energy they deliver, especially to fragile organic material such as paper. The current study concerns laser modification such as paper cleaning, initially o ... Full text Cite

Micromanipulation of cells and microparticles using optical fibers

Conference Optics Infobase Conference Papers · January 1, 2011 Optical tweezers is a powerful tool which is used to capture and manipulate microscopic particles such as dielectric microspheres and cells. In the single optical trap the beam is strongly focused to a diffraction limited spot by a high numerical aperture ... Full text Cite

Optical tweezers and manipulation of PMMA beads in various conditions

Conference Progress in Biomedical Optics and Imaging Proceedings of SPIE · October 20, 2009 Laser optical trapping and micromanipulation of microparticles or cells and subcellular structures have gained remarkable interest in biomedical research and applications. Several laser sources are employed for the combination of a laser scalpel with an op ... Full text Cite

Optical tweezers and manipulation of PMMA beads in various conditions

Conference Optics Infobase Conference Papers · January 1, 2009 Laser optical trapping and micromanipulation of microparticles or cells and subcellular structures have gained remarkable interest in biomedical research and applications. Several laser sources are employed for the combination of a laser scalpel with an op ... Cite

Ultra-violet laser microbeam and optical trapping for cell micromanipulation

Conference Progress in Biomedical Optics and Imaging Proceedings of SPIE · November 5, 2007 In recent years, lasers for optical trapping and micromanipulation of microscopic particles or cells and subcellular structures, both in vivo and in vitro, have gained remarkable interest in biomedical research and applications. On the other hand, a highly ... Full text Cite