Scholars@Duke
Donald Patrick McDonnell

Donald Patrick McDonnell

Glaxo-Wellcome Distinguished Professor of Molecular Cancer Biology, in the School of Medicine
Pharmacology & Cancer Biology
donald.mcdonnell@duke.edu
Box 103057, Durham, NC 27710
2138 MSRB3, 3 Genome Court, Durham, NC 27710

Keywords

3T3 Cells 8-Bromo Cyclic Adenosine Monophosphate ADP-ribosyl Cyclase 1 Acetates Acetyl Coenzyme A Acetyltransferases Adolescent Adult Age Factors Aging Aldehyde Dehydrogenase Allosteric Regulation Amino Acid Motifs Amino Acid Sequence Androgen Receptor Antagonists Androgens Antigens, CD Antigens, Nuclear Antineoplastic Agents Antineoplastic Agents, Hormonal Apoptosis Aromatase Aryl Hydrocarbon Receptor Nuclear Translocator Atlases as Topic Autocrine Communication Benzhydryl Compounds Benzoates Binding Sites Biological Transport Biomimetic Materials Blotting, Western Bone and Bones Breast Breast Neoplasms Bruch Membrane COS Cells Cadherins Calcium Calcium-Calmodulin-Dependent Protein Kinase Kinase Carcinoma, Hepatocellular Cardiovascular System Cell Line, Tumor Cell Nucleus Cell Proliferation Cercopithecus aethiops Chemokine CXCL12 Child Cholestanetriol 26-Monooxygenase Cholesterol Cholesterol Side-Chain Cleavage Enzyme Chromans Chromatin Chromatin Immunoprecipitation Chrysenes Cinnamates Cluster Analysis Combinatorial Chemistry Techniques Consensus Sequence Cytoprotection DNA Primers DNA-Binding Proteins Dehydroepiandrosterone Dieldrin Diethylstilbestrol Dose-Response Relationship, Drug Down-Regulation Drug Design Drug Discovery Drug Evaluation, Preclinical Drug Interactions Drug Partial Agonism Drug Resistance Drug Resistance, Neoplasm Drug Screening Assays, Antitumor Drug Synergism E2F1 Transcription Factor Enhancer Elements, Genetic Enzyme Activation Enzyme Inhibitors Enzyme-Linked Immunosorbent Assay Estradiol Estradiol Antagonists Estradiol Congeners Estrenes Estriol Estrogen Antagonists Estrogen Receptor Modulators Estrogen Receptor alpha Estrogen Receptor beta Estrogen Replacement Therapy Estrogens Estrogens, Non-Steroidal Estrone Extracellular Matrix Female Flow Cytometry Furylfuramide Gene Expression Gene Expression Profiling Gene Expression Regulation Gene Expression Regulation, Neoplastic Gene Library Genes, Reporter Glucose Glucose Transporter Type 1 Gonadal Steroid Hormones Green Fluorescent Proteins HCT116 Cells HEK293 Cells Haplorhini HeLa Cells Heat-Shock Proteins Hematopoiesis Hepatocyte Nuclear Factor 4 Hexokinase Histone Acetyltransferases Histone Deacetylase Inhibitors Homeodomain Proteins Hormone Antagonists Humans Hydroxycholesterols Hydroxymethylglutaryl-CoA Synthase Immunoblotting Immunohistochemistry Immunosuppressive Agents Indoles Induced Pluripotent Stem Cells Inflammatory Breast Neoplasms Insecticides Insulin-Like Growth Factor I Interleukin-1beta Intracellular Signaling Peptides and Proteins Kruppel-Like Transcription Factors Leupeptins Ligands Lipofuscin Lipoproteins, LDL Locus Coeruleus MCF-7 Cells MSX1 Transcription Factor Macrophages Macular Degeneration Male Mammary Glands, Human Metribolone Mice Mice, Congenic Mice, Inbred BALB C Mice, Inbred C57BL Mice, Inbred NOD Mice, Knockout Mice, Nude Mice, SCID Mice, Transgenic Microscopy, Electron Middle Aged Mifepristone Mitochondria Mitogen-Activated Protein Kinases Molecular Conformation Molecular Sequence Data Molecular Targeted Therapy Multiple Myeloma Mutagenesis, Site-Directed NF-kappa B Norepinephrine Nuclear Receptor Co-Repressor 1 Nuclear Receptor Co-Repressor 2 Nuclear Receptor Coactivator 1 Nuclear Receptor Coactivator 2 Nuclear Receptor Coactivators Organ Size Orphan Nuclear Receptors Osteoblasts Osteoclasts Osteogenesis Osteoporosis Ovariectomy Oxidation-Reduction PPAR gamma Peptide Library Peroxidase Peroxisome Proliferator-Activated Receptors Phenols Pigment Epithelium of Eye Plicamycin Polymerase Chain Reaction Progesterone Progestins Promegestone Promoter Regions, Genetic Prostate-Specific Antigen Prostatic Neoplasms Protein Conformation Protein Kinase Inhibitors Protein Kinases Protein Stability Protein Structure, Secondary Protein Structure, Tertiary Protein-Serine-Threonine Kinases Proteins Proteolysis RNA Interference RNA, Messenger RNA, Small Interfering RNA-Binding Proteins Raloxifene Hydrochloride Rats Rats, Sprague-Dawley Rats, Wistar Reactive Oxygen Species Receptor Cross-Talk Receptor, IGF Type 1 Receptor, erbB-2 Receptors, Androgen Receptors, Aryl Hydrocarbon Receptors, CXCR4 Receptors, Calcitriol Receptors, Cytoplasmic and Nuclear Receptors, Estrogen Receptors, Glucocorticoid Receptors, Progesterone Receptors, Retinoic Acid Receptors, Steroid Recombinant Fusion Proteins Recombinant Proteins Repetitive Sequences, Nucleic Acid Repressor Proteins Response Elements Retinal Dehydrogenase Retinal Pigment Epithelium Retinoblastoma Protein Retinoid X Receptor alpha Retinoid X Receptors Retinoids Reverse Transcriptase Polymerase Chain Reaction Saccharomyces cerevisiae Saccharomyces cerevisiae Proteins Selective Estrogen Receptor Modulators Sequence Deletion Species Specificity Stem Cell Transplantation Steroid 17-alpha-Hydroxylase Steroid Hydroxylases Steroids Stilbenes Structure-Activity Relationship T-Lymphocytes Tacrolimus Binding Proteins Tamoxifen Thiazolidinediones Tight Junctions Toxaphene Trans-Activators Transcription Factor AP-1 Transcription Factors Transcription, Genetic Transcriptional Activation Transfection Translocation, Genetic Tretinoin Tumor Burden Two-Hybrid System Techniques Ubiquitin-Protein Ligase Complexes Ubiquitin-Protein Ligases Up-Regulation Uterus Vascular Endothelial Growth Factor A Wnt Proteins Young Adult beta Catenin