Donald Patrick McDonnell

Book section · January 1, 2008 The classical models of nuclear receptor pharmacology held that agonists functioned by binding to their cognate receptors facilitating their conversion from an inactive form to one that was capable of activating transcription. By extrapolation, it was cons ... Full text Cite

Molecular Pharmacology of Estrogen and Progesterone Receptors

Book section · January 1, 2007 This chapter provides an update on the mechanisms of action of estrogen and progesterone. Particularly important concepts include nongenomic effects, receptor isoforms that affect agonist/antagonist actions, and the role of coactivators and corepressors in ... Full text Cite