Scholars@Duke
Dongfeng Chen

Dongfeng Chen

Associate Professor in Pathology
Pathology
dongfeng.chen@duke.edu
Duke Box 3712, RM116, Res Park III, 14 Circuit Dr, Durham, NC 27710
14 Circuit Drive, Research Park Building 3, Durham, NC 27710

Current Appointments & Affiliations

Associate Professor in Pathology · 2021 - Present Pathology, Clinical Science Departments

Recent Publications

Effect of Therapeutic Plasma Exchange-Containing Regimens on Donor Specific Antibodies in Patients With Antibody Mediated Rejection of Pulmonary Transplant.

Journal Article J Clin Apher · April 2025 Prior studies examining therapeutic plasma exchange (TPE)-containing regimens in pulmonary transplant antibody-mediated rejection (AMR) have been limited by sample size and inconsistent application of TPE. In this single-center, retrospective study, patien ... Full text Link to item Cite

Interrogating post-transplant donor HLA-specific antibody characteristics and effector functions using clinical bead assays.

Journal Article Hum Immunol · November 2024 Single antigen bead (SAB) assays are the most common and sensitive method used to detect and monitor post-transplant donor specific HLA antibodies (DSA). However, a direct comparison across traditional and modified SAB assays to improve routine DSA monitor ... Full text Link to item Cite

Allosensitisation in NHP results in cross-reactive anti-SLA antibodies not detected by a lymphocyte-based flow cytometry crossmatch.

Journal Article HLA · July 2024 Xenotransplantation is a potential option for individuals for whom an acceptable human allograft is unavailable. Individuals with broadly reactive HLA antibodies due to prior exposure to foreign HLA are potential candidates for a clinical xenotransplant tr ... Full text Cite
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