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Dongfeng Chen

Associate Professor in Pathology
Pathology
Duke Box 3712, RM116, Res Park III, 14 Circuit Dr, Durham, NC 27710
14 Circuit Drive, Research Park Building 3, Durham, NC 27710

Current Appointments & Affiliations


Associate Professor in Pathology · 2021 - Present Pathology, Clinical Science Departments

Recent Publications


Effect of Therapeutic Plasma Exchange-Containing Regimens on Donor Specific Antibodies in Patients With Antibody Mediated Rejection of Pulmonary Transplant.

Journal Article J Clin Apher · April 2025 Prior studies examining therapeutic plasma exchange (TPE)-containing regimens in pulmonary transplant antibody-mediated rejection (AMR) have been limited by sample size and inconsistent application of TPE. In this single-center, retrospective study, patien ... Full text Link to item Cite

Interrogating post-transplant donor HLA-specific antibody characteristics and effector functions using clinical bead assays.

Journal Article Hum Immunol · November 2024 Single antigen bead (SAB) assays are the most common and sensitive method used to detect and monitor post-transplant donor specific HLA antibodies (DSA). However, a direct comparison across traditional and modified SAB assays to improve routine DSA monitor ... Full text Link to item Cite

Allosensitisation in NHP results in cross-reactive anti-SLA antibodies not detected by a lymphocyte-based flow cytometry crossmatch.

Journal Article HLA · July 2024 Xenotransplantation is a potential option for individuals for whom an acceptable human allograft is unavailable. Individuals with broadly reactive HLA antibodies due to prior exposure to foreign HLA are potential candidates for a clinical xenotransplant tr ... Full text Cite
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