Dorothy Elizabeth Dow | Scholars@Duke

Dorothy Elizabeth Dow
Associate Professor of Pediatrics

Dorothy Dow, MD, MSc is Assistant Professor of Pediatrics and Assistant Research Professor at the Duke Global Health Institute. Dr. Dow’s research focuses on prevention and treatment of HIV in pediatric populations including prevention of mother-to-child transmission and a focus on adolescent and young adult populations. Dr. Dow is co-chair of IMPAACT Network Protocol 2016 and a member of the AHISA network. She is co-site leader of the Kilimanjaro Christian Medical Centre-Duke University Collaboration where she works nearly full time in Moshi, Tanzania, though returns to Duke University Medical Center two-weeks twice per year to attend on the clinical inpatient consult service.

Current Appointments & Affiliations

Associate Professor of Pediatrics, Pediatrics, Infectious Diseases, Pediatrics 2022
Associate Research Professor of Global Health, Duke Global Health Institute, University Institutes and Centers 2022

Contact Information

2301 Erwin Road, Durham, NC 27710
DUMC, Box 3499, Durham, NC 27710
dorothy.dow@duke.edu (919) 684-6335

Background
Education, Training, & Certifications
- Fellowship, Pediatric Infectious Diseases, Duke University School of Medicine 2010 - 2014
- MScGH, Duke University 2012
- Residency, Pediatrics, University of Texas Health Science Center San Antonio 2006 - 2009
- M.D., University of Texas Health Science Center San Antonio 2006
Previous Appointments & Affiliations
- Assistant Research Professor of Global Health, Duke Global Health Institute, University Institutes and Centers 2015 - 2022
- Assistant Professor of Pediatrics, Pediatrics, Infectious Diseases, Pediatrics 2021 - 2022
- Assistant Professor of Pediatrics, Pediatrics, Infectious Diseases, Pediatrics 2015 - 2020
- Medical Instructor in the Department of Pediatrics, Pediatrics, Infectious Diseases, Pediatrics 2014 - 2015
Recognition
In the News
- APR 15, 2022 School of Medicine
  
  School of Medicine Celebrates 2022 Faculty Achievement Awards
- JAN 25, 2019 Duke Global Health Institute
  
  A Novel Approach to Treating Teen HIV in Tanzania
- NOV 14, 2017 Duke Global Health Institute Newsletter
  
  DGHI Assistant Professor Tests Mental Health Interventions in Teens with HIV in Tanzania
- SEP 26, 2017 Fogarty International Newsletter
  
  Profile: Fogarty Fellow Dr Dorothy Dow studies suicide prevention in teens with HIV in Tanzania
Awards & Honors
- Society for Pediatric Research. SPR. 2017
Expertise
Global Scholarship
- Research
  - United Republic of Tanzania (Country)
Research
Selected Grants
- Evaluating the Effectiveness of Sauti ya Vijana (The Voice of Youth), a Mental Health and Life Skills Intervention to Improve HIV Outcomes Among Young People Living with HIV in Tanzania awarded by National Institutes of Health 2021 - 2026
- Interdisciplinary Research Training Program in AIDS awarded by National Institutes of Health 2010 - 2025
- LOC-IMPAACT 2016 Protocol Co-Chair support awarded by Johns Hopkins University 2017 - 2022
- Integrating Mental Health into HIV Clinic to Improve Outcomes in Tanzanian Youth awarded by National Institutes of Health 2015 - 2020
- Vanderbilt-Emory-Cornell-Duke Consortium for Global Health Fellows (VECDor) awarded by Vanderbilt University 2014 - 2016
External Relationships
- Kilimanjaro Christian Medical Center
Publications & Artistic Works
Selected Publications
- Academic Articles
  - Lowenthal, Elizabeth D., Stephanie M. DeLong, Brian Zanoni, Irene Njuguna, Kristin Beima-Sofie, Dorothy Dow, Aisa Shayo, et al. “Impact of COVID-19 on Adolescent HIV Prevention and Treatment Research in the AHISA Network.” Aids Behav, September 12, 2022. https://doi.org/10.1007/s10461-022-03811-5.
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  - Nelson, LaRon E., Adedotun Ogunbajo, Gamji Rabiu Abu-Ba’are, Donaldson F. Conserve, Leo Wilton, Jackson Junior Ndenkeh, Paula Braitstein, et al. “Using the Implementation Research Logic Model as a Lens to View Experiences of Implementing HIV Prevention and Care Interventions with Adolescent Sexual Minority Men-A Global Perspective.” Aids Behav, August 10, 2022. https://doi.org/10.1007/s10461-022-03776-5.
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  - Dow, Dorothy E., Karen E. O’Donnell, Laura Mkumba, John A. Gallis, Elizabeth L. Turner, Judith Boshe, Aisa M. Shayo, Coleen K. Cunningham, and Blandina T. Mmbaga. “Sauti ya Vijana (SYV; The Voice of Youth): Longitudinal Outcomes of an Individually Randomized Group Treatment Pilot Trial for Young People Living with HIV in Tanzania.” Aids Behav 26, no. 6 (June 2022): 2015–25. https://doi.org/10.1007/s10461-021-03550-z.
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  - Hosaka, Kalei R. J., Blandina T. Mmbaga, Aisa M. Shayo, John A. Gallis, Elizabeth L. Turner, Karen E. O’Donnell, Coleen K. Cunningham, Judith Boshe, and Dorothy E. Dow. “A group-based mental health intervention for Tanzanian youth living with HIV: Secondary analysis of a pilot trial.” Medicine (Baltimore) 101, no. 7 (February 18, 2022): e28693. https://doi.org/10.1097/MD.0000000000028693.
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  - Obasi, Angela, Maaike Seekles, Judith Boshe, Dorothy Dow, Blandina Mmbaga, Fileuka Ngakongwa, Elialilia Okello, et al. “Adolescent mental health research in Tanzania: a study protocol for a priority setting exercise and the development of an interinstitutional capacity strengthening programme.” Bmj Open 12, no. 2 (February 2, 2022): e054163. https://doi.org/10.1136/bmjopen-2021-054163.
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  - Hosaka, Kalei R. J., Blandina T. Mmbaga, John A. Gallis, and Dorothy E. Dow. “Feasibility and acceptability of a peer youth led curriculum to improve HIV knowledge in Northern Tanzania: resilience and intervention experience from the perspective of peer leaders.” Bmc Public Health 21, no. 1 (October 23, 2021): 1925. https://doi.org/10.1186/s12889-021-11876-5.
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  - Dow, Dorothy E., Blandina T. Mmbaga, John A. Gallis, Elizabeth L. Turner, Monica Gandhi, Coleen K. Cunningham, and Karen E. O’Donnell. “A group-based mental health intervention for young people living with HIV in Tanzania: results of a pilot individually randomized group treatment trial.” Bmc Public Health 20, no. 1 (September 4, 2020): 1358. https://doi.org/10.1186/s12889-020-09380-3.
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  - Cherenack, E. M., J. Rubli, D. E. Dow, and K. J. Sikkema. “Sexual Risk Behaviors and Menstrual and Intravaginal Practices Among Adolescent Girls and Young Women in Tanzania: A Cross-Sectional, School-Based Study.” International Journal of Sexual Health 32, no. 4 (January 1, 2020): 394–407. https://doi.org/10.1080/19317611.2020.1821861.
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  - Masese, Rita V., Julia V. Ramos, Leonia Rugalabamu, Severa Luhanga, Aisa M. Shayo, Kearsley A. Stewart, Coleen K. Cunningham, and Dorothy E. Dow. “Challenges and facilitators of transition from adolescent to adult HIV care among young adults living with HIV in Moshi, Tanzania.” J Int Aids Soc 22, no. 10 (October 2019): e25406. https://doi.org/10.1002/jia2.25406.
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  - Dow, Dorothy E., Aisa M. Shayo, Coleen K. Cunningham, and Blandina T. Mmbaga. “HIV-1 Drug Resistance and Virologic Outcomes Among Tanzanian Youth Living With HIV.” Pediatr Infect Dis J 38, no. 6 (June 2019): 617–19. https://doi.org/10.1097/INF.0000000000002288.
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  - Ryakitimbo, Amon, Amos Msekandiana, Zachary Tabb, Grace Kinabo, and Dorothy Dow. “A 12-Year-Old Tanzanian Boy With Headache: A Case Report.” Glob Pediatr Health 6 (2019): 2333794X18822995. https://doi.org/10.1177/2333794X18822995.
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  - Tabb, Zachary J., Blandina T. Mmbaga, Monica Gandhi, Alexander Louie, Karen Kuncze, Hideaki Okochi, Aisa M. Shayo, Elizabeth L. Turner, Coleen K. Cunningham, and Dorothy E. Dow. “Antiretroviral drug concentrations in hair are associated with virologic outcomes among young people living with HIV in Tanzania.” Aids 32, no. 9 (June 1, 2018): 1115–23. https://doi.org/10.1097/QAD.0000000000001788.
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  - Gichane, Margaret W., Kristen A. Sullivan, Aisa M. Shayo, Blandina T. Mmbaga, Karen O’ Donnell, Coleen K. Cunningham, and Dorothy E. Dow. “Caregiver role in HIV medication adherence among HIV-infected orphans in Tanzania.” Aids Care 30, no. 6 (June 2018): 701–5. https://doi.org/10.1080/09540121.2017.1391986.
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  - Dow, D. E., and P. C. Seed. “Clostridium difficile cure with fecal microbiota transplantation in a child with Pompe disease: a case report.” J Med Case Rep 12, no. 1 (April 28, 2018): 112. https://doi.org/10.1186/s13256-018-1659-2.
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  - Dow, Dorothy E., Blandina T. Mmbaga, Elizabeth L. Turner, John A. Gallis, Zachary J. Tabb, Coleen K. Cunningham, and Karen E. O’Donnell. “Building resilience: a mental health intervention for Tanzanian youth living with HIV.” Aids Care 30, no. sup4 (2018): 12–20. https://doi.org/10.1080/09540121.2018.1527008.
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  - Ramos, Julia V., Blandina T. Mmbaga, Elizabeth L. Turner, Leonia L. Rugalabamu, Severa Luhanga, Coleen K. Cunningham, and Dorothy E. Dow. “Modality of Primary HIV Disclosure and Association with Mental Health, Stigma, and Antiretroviral Therapy Adherence in Tanzanian Youth Living with HIV.” Aids Patient Care Stds 32, no. 1 (January 2018): 31–37. https://doi.org/10.1089/apc.2017.0196.
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  - Dow, Dorothy E., Werner Schimana, Balthazar M. Nyombi, Blandina T. Mmbaga, Aisa M. Shayo, John A. Bartlett, Charles G. Massambu, et al. “HIV Resistance and Prevention of Mother-to-Child Transmission Regimen in HIV-Infected Infants in Northern Tanzania.” Aids Res Hum Retroviruses 33, no. 11 (November 2017): 1107–13. https://doi.org/10.1089/AID.2017.0025.
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  - Boerma, Ragna S., Torsak Bunupuradah, Dorothy Dow, Joseph Fokam, Azar Kariminia, Dara Lehman, Cissy Kityo, et al. “Multicentre analysis of second-line antiretroviral treatment in HIV-infected children: adolescents at high risk of failure.” J Int Aids Soc 20, no. 1 (September 15, 2017): 21930. https://doi.org/10.7448/IAS.20.1.21930.
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  - Dahinten, Alexander P., Dorothy E. Dow, Coleen K. Cunningham, Levina J. Msuya, Blandina T. Mmbaga, and Robert A. Malkin. “Providing Safe and Effective Preventative Antiretroviral Prophylaxis to HIV-exposed Newborns via a Novel Drug Delivery System in Tanzania.” Pediatr Infect Dis J 35, no. 9 (September 2016): 987–91. https://doi.org/10.1097/INF.0000000000001224.
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  - Dow, Dorothy E., Elizabeth L. Turner, Aisa M. Shayo, Blandina Mmbaga, Coleen K. Cunningham, and Karen O’Donnell. “Evaluating mental health difficulties and associated outcomes among HIV-positive adolescents in Tanzania.” Aids Care 28, no. 7 (July 2016): 825–33. https://doi.org/10.1080/09540121.2016.1139043.
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  - Ramaiya, Megan K., Kristen A. Sullivan, Karen O’ Donnell, Coleen K. Cunningham, Aisa M. Shayo, Blandina T. Mmbaga, and Dorothy E. Dow. “A Qualitative Exploration of the Mental Health and Psychosocial Contexts of HIV-Positive Adolescents in Tanzania.” Plos One 11, no. 11 (2016): e0165936. https://doi.org/10.1371/journal.pone.0165936.
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  - Dow, Dorothy E., and John A. Bartlett. “Dolutegravir, the Second-Generation of Integrase Strand Transfer Inhibitors (INSTIs) for the Treatment of HIV.” Infect Dis Ther 3, no. 2 (December 2014): 83–102. https://doi.org/10.1007/s40121-014-0029-7.
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  - Dow, Dorothy E., Aisa M. Shayo, Coleen K. Cunningham, and Elizabeth A. Reddy. “Durability of antiretroviral therapy and predictors of virologic failure among perinatally HIV-infected children in Tanzania: a four-year follow-up.” Bmc Infect Dis 14 (November 7, 2014): 567. https://doi.org/10.1186/s12879-014-0567-3.
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  - Dow, Dorothy E., Coleen K. Cunningham, and Ann M. Buchanan. “A Review of Human Herpesvirus 8, the Kaposi's Sarcoma-Associated Herpesvirus, in the Pediatric Population.” J Pediatric Infect Dis Soc 3, no. 1 (March 2014): 66–76. https://doi.org/10.1093/jpids/pit051.
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  - Buchanan, Ann M., Dorothy E. Dow, Charles G. Massambu, Balthazar Nyombi, Aisa Shayo, Rahma Musoke, Sheng Feng, John A. Bartlett, Coleen K. Cunningham, and Werner Schimana. “Progress in the prevention of mother to child transmission of HIV in three regions of Tanzania: a retrospective analysis.” Plos One 9, no. 2 (2014): e88679. https://doi.org/10.1371/journal.pone.0088679.
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  - O’Donnell, Karen, Jia Yao, Jan Ostermann, Nathan Thielman, Elisabeth Reddy, Rachel Whetten, Venance Maro, et al. “Low rates of child testing for HIV persist in a high-risk area of East Africa.” Aids Care 26, no. 3 (2014): 326–31. https://doi.org/10.1080/09540121.2013.819405.
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  - Nsheha, Amos Haki, Dorothy Elizabeth Dow, Gabriel Erick Kapanda, Bernardus Carolus Hamel, and Levina January Msuya. “Adherence to antiretroviral therapy among HIV-infected children receiving care at Kilimanjaro Christian Medical Centre (KCMC), Northern Tanzania: A cross- sectional analytical study.” Pan Afr Med J 17 (2014): 238. https://doi.org/10.11604/pamj.2014.17.238.2280.
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  - Guadalupe, Moraima, Brad H. Pollock, Steven Westbrook, Spencer Redding, Delia Bullock, Gregory Anstead, Brian K. Agan, et al. “Risk factors influencing antibody responses to Kaposi's sarcoma-associated herpesvirus latent and lytic antigens in patients under antiretroviral therapy.” J Acquir Immune Defic Syndr 56, no. 1 (January 1, 2011): 83–90. https://doi.org/10.1097/QAI.0b013e3181fdc928.
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Scholarly, Clinical, & Service Activities
Presentations & Appearances
- Association of Self-Reported Adherence and Antiretroviral Drug Concentrations in Hair with Virologic Outcomes Among Tanzanian Youth. CFAR Fall Retreat. Center for AIDS Research. September 18, 2017 2017
- Adolescent HIV: How to Break the Mortality Wave. John Hope Franklin Center. October 19, 2016 2016
Outreach & Engaged Scholarship
- Global Health Outreach. Understanding Barriers and Successes in Transition of Adolescent to Adult HIV Care in Tanzania. Kilimanjaro Christian Medical Center . December 2016 2016
- Global Health Outreach. Evaluation of mental health difficulties in HIV infected adolescents. Kilimanjaro Christian Medical Center . July 2015 2015
Service to the Profession
- Member. Adolescent HIV Prevention and Treatment Implementation Science Alliance (AHISA). Fogarty International Center, National Institutes of Health. March 2017 2017
- IMPAACT 2016, co-chair. International Maternal Pediatric Adolescent AIDS Clinical Trials Network. 2015 2015
Academic & Administrative Activities
- Co-site leader of Kilimanjaro Christian Medical Centre-Duke University Collaboration in Moshi, Tanzania
Clinical Activities
- Inpatient pediatric infectious diseases consult service attending

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Education, Training, & Certifications

Previous Appointments & Affiliations

In the News

Awards & Honors

Global Scholarship

Research

Selected Grants

External Relationships

Selected Publications

Academic Articles

Presentations & Appearances

Outreach & Engaged Scholarship

Service to the Profession

Academic & Administrative Activities

Clinical Activities