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Elizabeth N Pavlisko

Professor of Pathology
Pathology
40 Medicine Circle, South Clin, Davison Building, Rm 203M, Durham, NC 27710
Department of Pathology, 3712, Durham, NC 27710

Featured Works


Banff study of pathologic changes in lung allograft biopsy specimens with donor-specific antibodies.

Journal article J Heart Lung Transplant · January 2016 Featured Publication BACKGROUND: The diagnosis of antibody-mediated rejection (AMR) in the lung transplant is still an area under investigation. We performed a blinded multicenter study to determine if any statistically significant histologic findings in transbronchial biopsy ... Full text Link to item Cite

Sarcomatoid Peritoneal Mesothelioma

Journal article American Journal of Surgical Pathology · December 2015 Featured Publication Full text Cite

Impact of CLAD Phenotype on Survival After Lung Retransplantation: A Multicenter Study.

Journal article Am J Transplant · August 2015 Featured Publication Chronic lung allograft dysfunction (CLAD) remains a major problem after lung transplantation with no definitive treatment except redo lung transplantation (re-LTx) in selected candidates. However, CLAD is not a homogeneous entity and different phenotypes e ... Full text Link to item Cite

Elevated Hyaluronan Is Associated with Bronchiolitis Obliterans Syndrome

Conference The Journal of Heart and Lung Transplantation · April 2014 Featured Publication Full text Cite

Hyaluronan contributes to bronchiolitis obliterans syndrome and stimulates lung allograft rejection through activation of innate immunity.

Journal article Am J Respir Crit Care Med · March 1, 2014 Featured Publication RATIONALE: Although innate immunity is increasingly recognized to contribute to lung allograft rejection, the significance of endogenous innate ligands, such as hyaluronan (HA) fragments, in clinical or experimental lung transplantation is uncertain. OBJEC ... Full text Link to item Cite

Impact of forced vital capacity loss on survival after the onset of chronic lung allograft dysfunction.

Journal article Am J Respir Crit Care Med · January 15, 2014 Featured Publication RATIONALE: Emerging evidence suggests a restrictive phenotype of chronic lung allograft dysfunction (CLAD) exists; however, the optimal approach to its diagnosis and clinical significance is uncertain. OBJECTIVES: To evaluate the hypothesis that spirometri ... Full text Link to item Cite

Lung cancer (exposure assessment, pathology, and epidemiology)

Book section · January 1, 2014 Featured Publication Lung cancer is the most common malignancy worldwide and the most common cause of a cancer-related death. Tobacco smoking is the most important cause of lung cancer in most populations although occupational exposures cause an increased risk of lung cancer m ... Full text Cite

Epithelial clara cell injury occurs in bronchiolitis obliterans syndrome after human lung transplantation.

Journal article Am J Transplant · November 2012 Featured Publication Bronchiolitis obliterans syndrome (BOS) is a condition of progressive airflow obstruction that affects a majority of lung transplant recipients and limits long-term posttransplant survival. Although epithelial injury appears central to the development of B ... Full text Link to item Cite

Disruption of iron homeostasis in mesothelial cells after talc pleurodesis.

Journal article Am J Respir Cell Mol Biol · January 2012 Featured Publication The mechanism for biological effects after exposure to particles is incompletely understood. One postulate proposed to explain biological effects after exposure to particles involves altered iron homeostasis in the host. The fibro-inflammatory properties o ... Full text Link to item Cite

Acute allograft rejection: cellular and humoral processes.

Journal article Clin Chest Med · June 2011 Featured Publication Acute cellular rejection affects greater than one-third of lung transplant recipients. Alloreactive T-lymphocytes constitute the basis of lung allograft rejection. Recent evidence supports a more complex immune response to the allograft. Interaction betwee ... Full text Link to item Cite