Emily O'Brien | Scholars@Duke

Emily O'Brien
Assistant Professor in Population Health Sciences

I am an epidemiologist and health services researcher at the Duke Clinical Research Institute. My research focuses on comparative effectiveness, patient-centered outcomes, and pragmatic health services research in cardiovascular and pulmonary disease.

Areas of expertise: Epidemiology, Health Services Research, and Clinical Decision Sciences

Current Appointments & Affiliations

Assistant Professor in Population Health Sciences, Population Health Sciences, Basic Science Departments 2018
Assistant Professor in Neurology, Neurology, Clinical Science Departments 2018
Membership in the Duke Clinical Research Institute, Duke Clinical Research Institute, Institutes and Centers 2013
Core Faculty Member, Duke-Margolis Center for Health Policy, Duke - Margolis Center For Health Policy, Initiatives 2019

Contact Information

2400 Pratt Street, Duke Clin. Research Inst. 6th Floor, Durham, NC 27707
emily.obrien@duke.edu (919) 668-0670

Background
Education, Training, & Certifications
- Ph.D., University of North Carolina at Chapel Hill 2012
Duke Appointment History
- Assistant Professor in Population Health Sciences, Population Health Sciences, Basic Science Departments 2017 - 2018
- Assistant Professor in Medicine, Medicine, Clinical Pharmacology, Medicine 2015 - 2017
- Medical Instructor in the Department of Medicine, Medicine, Clinical Pharmacology, Medicine 2013 - 2015
- Instructor Temporary in the Department of Medicine, Medicine, Clinical Pharmacology, Medicine 2013
Recognition
In the News
- APR 13, 2020
  
  Health Care Workers Encouraged to Join COVID-19 Clinical Trial Registry
- MAY 3, 2018 Population Health Learning Network
  
  Minor bleeding not tied to risk of major bleeding in AF patients
- NOV 16, 2016 Everyday Health
  
  Many With Common Atrial Fibrillation Unaware of Stroke Risk
- NOV 14, 2016 Duke Health News
  
  Nearly A Third of Newly Diagnosed AFib Patients Don't Understand Stroke Risk
- NOV 3, 2016 Reuters Health
  
  ED crowding tied to potentially fatal delays in stroke care
- JUL 13, 2016 MedWire News
  
  Sacubitril plus valsartan reduces early readmission risk in HF
- MAR 1, 2016 Duke Medicine News
  
  Q & A with Emily O’Brien: Disparities research “the heart of public health
- NOV 17, 2015 Neurology Advisor
  
  Depression Raises Stroke, Coronary Heart Disease Risk in African Americans
- MAR 5, 2015 Medpagetoday
  
  Stroke Rounds: Nearly A Million New Scripts for Prevention in Afib?
- MAR 3, 2015 Medscape
  
  Recent AF Guidelines Would Significantly Expand OAC Use
- MAR 2, 2015 Science Daily
  
  Guidelines suggest blood thinners for more women, seniors with AFib
- NOV 13, 2014 American Heart Association News
  
  New type of medical research centered on patient values and needs
Research
Selected Grants
- Collaboratory Resource Coordinating Center for Pragmatic and Implementation Studies for the Management of Pain (PRISM) (U24) awarded by National Institutes of Health 2019 - 2024
- Evaluating fitness-for-use of Electronic Health Records in Clinical Research awarded by Food and Drug Administration 2019 - 2022
- In-hospital Use of Sacubitril/Valsartan and Post-discharge Adherence and Clinical Outcomes Following Hospitalization for Heart Failure with Reduced Ejection Fraction 2019 - 2022
- HERO Program, HERO Registry, HERO-HCQ Trial awarded by Patient Centered Outcomes Research Institute 2020 - 2021
- Caregivers' Reactions and Experience: Imaging Dementia-Evidence for Amyloid Scanning-CARE IDEAS awarded by Brown University 2017 - 2021
- Jackson Heart Study Cardiovascular Disease (CVD) Working Group and Medicare Data Linkage 2019 - 2020
- Using PCORnet to Compare Blood Pressure Control Strategies (Subaward to UCSF) awarded by University of California, San Francisco 2018 - 2020
- Patient-centered Research into Outcomes Stroke patients Prefer and Effectiveness Research awarded by Patient Centered Outcomes Research Institute 2013 - 2020
- Methodology for Linking Clinical and Administrative Databases awarded by Patient Centered Outcomes Research Institute 2014 - 2019
- Jackson Heart Study Cardiovascular Disease (CVD) Working Group and Medicare Data Linkage 2019
- A Collaboration for Improving Outcomes of African Americans with Heart Failure awarded by National Institutes of Health 2013 - 2018
- Extraction Vs Capping Pacing and Defibrillator Leads 2015 - 2016
- Patient-centered Research into Outcomes Stroke patients Prefer and Effectiveness Research awarded by Patient Centered Outcomes Research Institute 2013 - 2016
Publications & Artistic Works
Selected Publications
- Academic Articles
  - Oshunbade, Adebamike A., Wondwosen K. Yimer, Karen A. Valle, Donald Clark, Daisuke Kamimura, Wendy B. White, Andrew P. DeFilippis, et al. “Cigarette Smoking and Incident Stroke in Blacks of the Jackson Heart Study.” J Am Heart Assoc 9, no. 12 (June 16, 2020): e014990. https://doi.org/10.1161/JAHA.119.014990.
    Full Text Link to Item
  - Spahillari, Aferdita, Jinyi Zhu, Bart S. Ferket, MG Myriam Hunink, J Jeffrey Carr, James G. Terry, Cheryl Nelson, et al. “Cost-effectiveness of Contemporary Statin Use Guidelines With or Without Coronary Artery Calcium Assessment in African American Individuals.” Jama Cardiol, May 13, 2020. https://doi.org/10.1001/jamacardio.2020.1240.
    Full Text Link to Item
  - Glover, LáShauntá M., Loretta R. Cain-Shields, Tanya M. Spruill, Emily C. O’Brien, Sharrelle Barber, Laura Loehr, and Mario Sims. “Goal-Striving Stress and Incident Cardiovascular Disease in Blacks: The Jackson Heart Study.” Journal of the American Heart Association 9, no. 9 (May 2020): e015707. https://doi.org/10.1161/jaha.119.015707.
    Full Text
  - O’Brien, Emily C., Anne S. Hellkamp, Megan L. Neely, Aparna Swaminathan, Shaun Bender, Laurie D. Snyder, Daniel A. Culver, et al. “Disease Severity and Quality of Life in Patients With Idiopathic Pulmonary Fibrosis: A Cross-Sectional Analysis of the IPF-PRO Registry.” Chest 157, no. 5 (May 2020): 1188–98. https://doi.org/10.1016/j.chest.2019.11.042.
    Full Text Link to Item
  - Rockhold, Frank W., Jessica D. Tenenbaum, Rachel Richesson, Keith A. Marsolo, and Emily C. O’Brien. “Design and analytic considerations for using patient-reported health data in pragmatic clinical trials: report from an NIH Collaboratory roundtable.” J Am Med Inform Assoc 27, no. 4 (April 1, 2020): 634–38. https://doi.org/10.1093/jamia/ocz226.
    Full Text Open Access Copy Link to Item
  - Pletcher, Mark J., Valy Fontil, Thomas Carton, Kathryn M. Shaw, Myra Smith, Sujung Choi, Jonathan Todd, et al. “The PCORnet Blood Pressure Control Laboratory: A Platform for Surveillance and Efficient Trials.” Circ Cardiovasc Qual Outcomes 13, no. 3 (March 2020): e006115. https://doi.org/10.1161/CIRCOUTCOMES.119.006115.
    Full Text Link to Item
  - Curti, Steven A., Joseph A. DeGruy, Christopher Spankovich, Charles E. Bishop, Dan Su, Karen Valle, Emily O’Brien, Yuan-I Min, and John M. Schweinfurth. “Relationship of Overall Cardiovascular Health and Hearing Loss in The Jackson Heart Study Population.” Laryngoscope, December 26, 2019. https://doi.org/10.1002/lary.28469.
    Full Text Link to Item
  - Kaufman, Brystana G., Emily C. O’Brien, Sally C. Stearns, Roland Matsouaka, G Mark Holmes, Morris Weinberger, Paula H. Song, et al. “The Medicare Shared Savings Program and Outcomes for Ischemic Stroke Patients: a Retrospective Cohort Study.” J Gen Intern Med 34, no. 12 (December 2019): 2740–48. https://doi.org/10.1007/s11606-019-05283-1.
    Full Text Link to Item
  - Steinberg, Benjamin A., Nicholas G. Ballew, Melissa A. Greiner, Steven J. Lippmann, Lesley H. Curtis, Emily C. O’Brien, Manesh R. Patel, and Jonathan P. Piccini. “Ischemic and Bleeding Outcomes in Patients With Atrial Fibrillation and Contraindications to Oral Anticoagulation.” Jacc Clin Electrophysiol 5, no. 12 (December 2019): 1384–92. https://doi.org/10.1016/j.jacep.2019.07.011.
    Full Text Link to Item
  - Van Houtven, Courtney Harold, Katherine E. M. Miller, Emily C. O’Brien, Jennifer L. Wolff, Jennifer Lindquist, Margaret Kabat, Margaret Campbell-Kotler, Jennifer Henius, and Corrine I. Voils. “Development and Initial Validation of the Caregiver Perceptions About Communication With Clinical Team Members (CAPACITY) Measure.” Med Care Res Rev 76, no. 6 (December 2019): 784–806. https://doi.org/10.1177/1077558717747985.
    Full Text Link to Item
  - Samsky, Marc D., Li Lin, Stephen J. Greene, Steven J. Lippmann, Pamela N. Peterson, Paul A. Heidenreich, Warren K. Laskey, et al. “Patient Perceptions and Familiarity With Medical Therapy for Heart Failure.” Jama Cardiol, November 17, 2019. https://doi.org/10.1001/jamacardio.2019.4987.
    Full Text Link to Item
  - Gillespie, Shannon L., Cindy M. Anderson, Songzhu Zhao, Yubo Tan, David Kline, Guy Brock, James Odei, et al. “Allostatic load in the association of depressive symptoms with incident coronary heart disease: The Jackson Heart Study.” Psychoneuroendocrinology 109 (November 2019): 104369. https://doi.org/10.1016/j.psyneuen.2019.06.020.
    Full Text Link to Item
  - Duell, P Barton, Samuel S. Gidding, Rolf L. Andersen, Thomas Knickelbine, Lars Anderson, Eugenia Gianos, Peter Shrader, et al. “Longitudinal low density lipoprotein cholesterol goal achievement and cardiovascular outcomes among adult patients with familial hypercholesterolemia: The CASCADE FH registry.” Atherosclerosis 289 (October 2019): 85–93. https://doi.org/10.1016/j.atherosclerosis.2019.08.007.
    Full Text Link to Item
  - O’Brien, Emily C., and Stephen J. Greene. “Real-World Evidence for Medication Safety: Causal, Confounded, or Capable?” Jacc Heart Fail 7, no. 10 (October 2019): 846–48. https://doi.org/10.1016/j.jchf.2019.05.003.
    Full Text Link to Item
  - Foraker, Randi E., Christopher Bush, Melissa A. Greiner, Mario Sims, Kamal Henderson, Sakima Smith, Aurelian Bidulescu, Abigail B. Shoben, N Chantelle Hardy, and Emily O’Brien. “Distribution of Cardiovascular Health by Individual- and Neighborhood-Level Socioeconomic Status: Findings From the Jackson Heart Study.” Glob Heart 14, no. 3 (September 2019): 241–50. https://doi.org/10.1016/j.gheart.2019.04.007.
    Full Text Link to Item
  - O’Brien, Eileen C., Ricardo Segurado, Aisling A. Geraghty, Goiuri Alberdi, Ewelina Rogozinska, Arne Astrup, Rubenomar Barakat Carballo, et al. “Impact of maternal education on response to lifestyle interventions to reduce gestational weight gain: individual participant data meta-analysis.” Bmj Open 9, no. 8 (August 1, 2019): e025620. https://doi.org/10.1136/bmjopen-2018-025620.
    Full Text Link to Item
  - Xian, Ying, Haolin Xu, Emily C. O’Brien, Shreyansh Shah, Laine Thomas, Michael J. Pencina, Gregg C. Fonarow, et al. “Clinical Effectiveness of Direct Oral Anticoagulants vs Warfarin in Older Patients With Atrial Fibrillation and Ischemic Stroke: Findings From the Patient-Centered Research Into Outcomes Stroke Patients Prefer and Effectiveness Research (PROSPER) Study.” Jama Neurol, July 22, 2019. https://doi.org/10.1001/jamaneurol.2019.2099.
    Full Text Open Access Copy Link to Item
  - Kaufman, Brystana G., Emily C. O’Brien, Sally C. Stearns, Roland A. Matsouaka, G Mark Holmes, Morris Weinberger, Lee H. Schwamm, et al. “Medicare Shared Savings ACOs and Hospice Care for Ischemic Stroke Patients.” J Am Geriatr Soc 67, no. 7 (July 2019): 1402–9. https://doi.org/10.1111/jgs.15852.
    Full Text Link to Item
  - O’Brien, Emily C., Ana Maria Rodriguez, Hye-Chung Kum, Laura E. Schanberg, Marcy Fitz-Randolph, Sean M. O’Brien, and Soko Setoguchi. “Patient perspectives on the linkage of health data for research: Insights from an online patient community questionnaire.” Int J Med Inform 127 (July 2019): 9–17. https://doi.org/10.1016/j.ijmedinf.2019.04.003.
    Full Text Link to Item
  - Thomas, Laine E., Emily C. O’Brien, Jonathan P. Piccini, Ralph B. D’Agostino, and Michael J. Pencina. “Application of net reclassification index to non-nested and point-based risk prediction models: a review.” Eur Heart J 40, no. 23 (June 14, 2019): 1880–87. https://doi.org/10.1093/eurheartj/ehy345.
    Full Text Link to Item
  - Kaufman, Brystana G., B Steven Spivack, Sally C. Stearns, Paula H. Song, and Emily C. O’Brien. “Impact of Accountable Care Organizations on Utilization, Care, and Outcomes: A Systematic Review.” Med Care Res Rev 76, no. 3 (June 2019): 255–90. https://doi.org/10.1177/1077558717745916.
    Full Text Link to Item
  - Pumill, Christopher A., Christopher G. Bush, Melissa A. Greiner, Michael E. Hall, Shannon M. Dunlay, Adolfo Correa, Lesley H. Curtis, et al. “Neck circumference and cardiovascular outcomes: Insights from the Jackson Heart Study.” Am Heart J 212 (June 2019): 72–79. https://doi.org/10.1016/j.ahj.2019.03.001.
    Full Text Link to Item
  - Shah, Shreyansh, Ying Xian, DaiWai M. Olson, Gregg C. Fonarow, Eric E. Smith, Lesley Maisch, and Emily C. O’Brien. “Home-time Is a Patient-Centered Outcome Variable for Stroke: An Executive Summary.” J Neurosci Nurs 51, no. 3 (June 2019): 110–12. https://doi.org/10.1097/JNN.0000000000000437.
    Full Text Link to Item
  - Snyder, Laurie, Megan L. Neely, Anne S. Hellkamp, Emily O’Brien, Joao de Andrade, Craig S. Conoscenti, Thomas Leonard, et al. “Predictors of death or lung transplant after a diagnosis of idiopathic pulmonary fibrosis: insights from the IPF-PRO Registry.” Respir Res 20, no. 1 (May 30, 2019): 105. https://doi.org/10.1186/s12931-019-1043-9.
    Full Text Link to Item
  - Khan, Sadiya S., Hongyan Ning, Sanjiv J. Shah, Clyde W. Yancy, Mercedes Carnethon, Jarett D. Berry, Robert J. Mentz, et al. “10-Year Risk Equations for Incident Heart Failure in the General Population.” J Am Coll Cardiol 73, no. 19 (May 21, 2019): 2388–97. https://doi.org/10.1016/j.jacc.2019.02.057.
    Full Text Link to Item
  - Holmes, DaJuanicia N., Jonathan P. Piccini, Larry A. Allen, Gregg C. Fonarow, Bernard J. Gersh, Peter R. Kowey, Emily C. O’Brien, et al. “Defining Clinically Important Difference in the Atrial Fibrillation Effect on Quality-of-Life Score.” Circ Cardiovasc Qual Outcomes 12, no. 5 (May 2019): e005358. https://doi.org/10.1161/CIRCOUTCOMES.118.005358.
    Full Text Link to Item
  - Luo, Nancy, Steven J. Lippmann, Robert J. Mentz, Melissa A. Greiner, Bradley G. Hammill, N Chantelle Hardy, Warren K. Laskey, et al. “Relationship Between Hospital Characteristics and Early Adoption of Angiotensin-Receptor/Neprilysin Inhibitor Among Eligible Patients Hospitalized for Heart Failure.” J Am Heart Assoc 8, no. 3 (February 5, 2019): e010484. https://doi.org/10.1161/JAHA.118.010484.
    Full Text Link to Item
  - O’Brien, Emily C., DaJuanicia N. Holmes, Laine Thomas, Daniel E. Singer, Gregg C. Fonarow, Kenneth W. Mahaffey, Peter R. Kowey, et al. “Incremental prognostic value of renal function for stroke prediction in atrial fibrillation.” Int J Cardiol 274 (January 1, 2019): 152–57. https://doi.org/10.1016/j.ijcard.2018.07.113.
    Full Text Link to Item
  - O’Brien, Emily C., Shuang Li, Laine Thomas, Tracy Y. Wang, Matthew T. Roe, and Eric D. Peterson. “The impact of clinical vs administrative claims coding on hospital risk-adjusted outcomes.” Clin Cardiol 41, no. 9 (September 2018): 1225–31. https://doi.org/10.1002/clc.23059.
    Full Text Link to Item
  - O’Brien, Emily C., DaJuanicia N. Holmes, Laine E. Thomas, Gregg C. Fonarow, Larry A. Allen, Bernard J. Gersh, Peter R. Kowey, et al. “Prognostic Significance of Nuisance Bleeding in Anticoagulated Patients With Atrial Fibrillation.” Circulation 138, no. 9 (August 28, 2018): 889–97. https://doi.org/10.1161/CIRCULATIONAHA.117.031354.
    Full Text Link to Item
  - Kaufman, Brystana G., David Klemish, Cordt T. Kassner, Jerome P. Reiter, Fan Li, Matthew Harker, Emily C. O’Brien, Donald H. Taylor, and Nrupen A. Bhavsar. “Predicting Length of Hospice Stay: An Application of Quantile Regression.” J Palliat Med 21, no. 8 (August 2018): 1131–36. https://doi.org/10.1089/jpm.2018.0039.
    Full Text Link to Item
  - Kelly, Jacob P., Melissa Greiner, Elsayed Z. Soliman, Tiffany C. Randolph, Kevin L. Thomas, Shannon M. Dunlay, Lesley H. Curtis, Emily C. O’Brien, and Robert J. Mentz. “Relation of Early Repolarization (J Point Elevation) to Mortality in Blacks (from the Jackson Heart Study).” Am J Cardiol 122, no. 2 (July 15, 2018): 340–46. https://doi.org/10.1016/j.amjcard.2018.04.004.
    Full Text Link to Item
  - Greene, Stephen J., Emily C. O’Brien, Robert J. Mentz, Nancy Luo, N Chantelle Hardy, Warren K. Laskey, Paul A. Heidenreich, et al. “Home-Time After Discharge Among Patients Hospitalized With Heart Failure.” J Am Coll Cardiol 71, no. 23 (June 12, 2018): 2643–52. https://doi.org/10.1016/j.jacc.2018.03.517.
    Full Text Link to Item
  - O’Brien, Emily C., DaJuanicia N. Holmes, Laine Thomas, Gregg C. Fonarow, Peter R. Kowey, Jack E. Ansell, Kenneth W. Mahaffey, et al. “Therapeutic Strategies Following Major, Clinically Relevant Nonmajor, and Nuisance Bleeding in Atrial Fibrillation: Findings From ORBIT-AF.” J Am Heart Assoc 7, no. 12 (June 9, 2018). https://doi.org/10.1161/JAHA.117.006391.
    Full Text Link to Item
  - Luo, Nancy, Nicholas G. Ballew, Emily C. O’Brien, Melissa A. Greiner, Pamela N. Peterson, Bradley G. Hammill, N Chantelle Hardy, et al. “Early impact of guideline publication on angiotensin-receptor neprilysin inhibitor use among patients hospitalized for heart failure.” Am Heart J 200 (June 2018): 134–40. https://doi.org/10.1016/j.ahj.2018.01.009.
    Full Text Link to Item
  - Mentz, Robert J., Melissa A. Greiner, Paul Muntner, Daichi Shimbo, Mario Sims, Tanya M. Spruill, Benjamin F. Banahan, et al. “Intentional and unintentional medication non-adherence in African Americans: Insights from the Jackson Heart Study.” Am Heart J 200 (June 2018): 51–59. https://doi.org/10.1016/j.ahj.2018.03.007.
    Full Text Link to Item
  - Bath, Philip M., Lisa J. Woodhouse, Jason P. Appleton, Maia Beridze, Hanne Christensen, Robert A. Dineen, Lelia Duley, et al. “Antiplatelet therapy with aspirin, clopidogrel, and dipyridamole versus clopidogrel alone or aspirin and dipyridamole in patients with acute cerebral ischaemia (TARDIS): a randomised, open-label, phase 3 superiority trial.” Lancet 391, no. 10123 (March 3, 2018): 850–59. https://doi.org/10.1016/S0140-6736(17)32849-0.
    Full Text Link to Item
  - Foraker, Randi E., Avirup Guha, Henry Chang, Emily C. O’Brien, Julie K. Bower, Elliott D. Crouser, Wayne D. Rosamond, and Subha V. Raman. “Survival After MI in a Community Cohort Study: Contribution of Comorbidities in NSTEMI.” Glob Heart 13, no. 1 (March 2018): 13–18. https://doi.org/10.1016/j.gheart.2018.01.002.
    Full Text Link to Item
  - Kaufman, Brystana G., Sunghee Kim, Karen Pieper, Larry A. Allen, Bernard J. Gersh, Gerald V. Naccarelli, Michael D. Ezekowitz, et al. “Disease understanding in patients newly diagnosed with atrial fibrillation.” Heart 104, no. 6 (March 2018): 494–501. https://doi.org/10.1136/heartjnl-2017-311800.
    Full Text Link to Item
  - Amrock, Stephen M., P Barton Duell, Thomas Knickelbine, Seth S. Martin, Emily C. O’Brien, Karol E. Watson, Joanna Mitri, et al. “Health disparities among adult patients with a phenotypic diagnosis of familial hypercholesterolemia in the CASCADE-FH™ patient registry.” Atherosclerosis 267 (December 2017): 19–26. https://doi.org/10.1016/j.atherosclerosis.2017.10.006.
    Full Text Link to Item
  - Luo, Nancy, Robert J. Mentz, and Emily C. O’Brien. “Reply: Adoption of Sacubitril/Valsartan Must Take Into Account Different Heart Failure Patient Types.” Jacc Heart Fail 5, no. 9 (September 2017): 689. https://doi.org/10.1016/j.jchf.2017.07.002.
    Full Text Link to Item
  - Parikh, Kishan S., Melissa A. Greiner, Wei Wang, Yuan-I Min, Adolfo Correa, Benjamin F. Banahan, Lesley H. Curtis, Adrian F. Hernandez, Emily C. O’Brien, and Robert J. Mentz. “Representativeness of Medicare Participants in the Jackson Heart Study for African American Medicare Beneficiaries.” Epidemiology 28, no. 5 (September 2017): 740–46. https://doi.org/10.1097/EDE.0000000000000689.
    Full Text Link to Item
  - Tajeu, Gabriel S., John N. Booth, Lisandro D. Colantonio, Rebecca F. Gottesman, George Howard, Daniel T. Lackland, Emily C. O’Brien, et al. “Incident Cardiovascular Disease Among Adults With Blood Pressure <140/90 mm Hg.” Circulation 136, no. 9 (August 29, 2017): 798–812. https://doi.org/10.1161/CIRCULATIONAHA.117.027362.
    Full Text Link to Item
  - Steinberg, Benjamin A., Peter Shrader, Laine Thomas, Jack Ansell, Gregg C. Fonarow, Bernard J. Gersh, Elaine Hylek, et al. “Factors associated with non-vitamin K antagonist oral anticoagulants for stroke prevention in patients with new-onset atrial fibrillation: Results from the Outcomes Registry for Better Informed Treatment of Atrial Fibrillation II (ORBIT-AF II).” Am Heart J 189 (July 2017): 40–47. https://doi.org/10.1016/j.ahj.2017.03.024.
    Full Text Link to Item
  - Anderson, Monique L., Rachel Peragallo Urrutia, Emily C. O’Brien, Nancy M. Allen LaPointe, Alexander J. Christian, Lisa A. Kaltenbach, Laura E. Webb, et al. “Outcomes of a multi-community hypertension implementation study: the American Heart Association's Check. Change. Control. program.” J Clin Hypertens (Greenwich) 19, no. 5 (May 2017): 479–87. https://doi.org/10.1111/jch.12950.
    Full Text Link to Item
  - Dunlay, Shannon M., Steven J. Lippmann, Melissa A. Greiner, Emily C. O’Brien, Alanna M. Chamberlain, Robert J. Mentz, and Mario Sims. “Perceived Discrimination and Cardiovascular Outcomes in Older African Americans: Insights From the Jackson Heart Study.” Mayo Clin Proc 92, no. 5 (May 2017): 699–709. https://doi.org/10.1016/j.mayocp.2017.01.024.
    Full Text Link to Item
  - Katz, David F., Thomas M. Maddox, Mintu Turakhia, Anil Gehi, Emily C. O’Brien, Steven A. Lubitz, Alexander Turchin, et al. “Contemporary Trends in Oral Anticoagulant Prescription in Atrial Fibrillation Patients at Low to Moderate Risk of Stroke After Guideline-Recommended Change in Use of the CHADS2 to the CHA2DS2-VASc Score for Thromboembolic Risk Assessment: Analysis From the National Cardiovascular Data Registry's Outpatient Practice Innovation and Clinical Excellence Atrial Fibrillation Registry.” Circ Cardiovasc Qual Outcomes 10, no. 5 (May 2017). https://doi.org/10.1161/CIRCOUTCOMES.116.003476.
    Full Text Link to Item
  - Luo, Nancy, Gregg C. Fonarow, Steven J. Lippmann, Xiaojuan Mi, Paul A. Heidenreich, Clyde W. Yancy, Melissa A. Greiner, et al. “Early Adoption of Sacubitril/Valsartan for Patients With Heart Failure With Reduced Ejection Fraction: Insights From Get With the Guidelines-Heart Failure (GWTG-HF).” Jacc Heart Fail 5, no. 4 (April 2017): 305–9. https://doi.org/10.1016/j.jchf.2016.12.018.
    Full Text Link to Item
  - Xian, Ying, Emily C. O’Brien, Li Liang, Haolin Xu, Lee H. Schwamm, Gregg C. Fonarow, Deepak L. Bhatt, et al. “Association of Preceding Antithrombotic Treatment With Acute Ischemic Stroke Severity and In-Hospital Outcomes Among Patients With Atrial Fibrillation.” Jama 317, no. 10 (March 14, 2017): 1057–67. https://doi.org/10.1001/jama.2017.1371.
    Full Text Link to Item
  - Gehi, Anil K., Emily O’Brien, Rajeev K. Pathak, Prashanthan Sanders, Kevin F. Kennedy, Salim S. Virani, Frederick A. Masoudi, and Thomas M. Maddox. “Implications of the LEGACY trial on US Atrial Fibrillation Patients: An NCDR Research to Practice (R2P) Project.” Am J Cardiol 119, no. 4 (February 15, 2017): 579–84. https://doi.org/10.1016/j.amjcard.2016.10.044.
    Full Text Link to Item
  - O’Brien, Emily C., Jingjing Wu, Xin Zhao, Phillip J. Schulte, Gregg C. Fonarow, Adrian F. Hernandez, Lee H. Schwamm, Eric D. Peterson, Deepak L. Bhatt, and Eric E. Smith. “Healthcare Resource Availability, Quality of Care, and Acute Ischemic Stroke Outcomes.” J Am Heart Assoc 6, no. 2 (February 3, 2017). https://doi.org/10.1161/JAHA.116.003813.
    Full Text Link to Item
  - Parikh, Kishan S., Melissa A. Greiner, Takeki Suzuki, Adam D. DeVore, Chad Blackshear, Joseph F. Maher, Lesley H. Curtis, Adrian F. Hernandez, Emily C. O’Brien, and Robert J. Mentz. “Resting Heart Rate and Long-term Outcomes Among the African American Population: Insights From the Jackson Heart Study.” Jama Cardiol 2, no. 2 (February 1, 2017): 172–80. https://doi.org/10.1001/jamacardio.2016.3234.
    Full Text Link to Item
  - Randolph, Tiffany C., Melissa A. Greiner, Chidiebube Egwim, Adrian F. Hernandez, Kevin L. Thomas, Lesley H. Curtis, Paul Muntner, Wei Wang, Robert J. Mentz, and Emily C. O’Brien. “Associations Between Blood Pressure and Outcomes Among Blacks in the Jackson Heart Study.” J Am Heart Assoc 5, no. 12 (December 7, 2016). https://doi.org/10.1161/JAHA.116.003928.
    Full Text Link to Item
  - O’Brien, Emily C., Ying Xian, Haolin Xu, Jingjing Wu, Jeffrey L. Saver, Eric E. Smith, Lee H. Schwamm, et al. “Hospital Variation in Home-Time After Acute Ischemic Stroke: Insights From the PROSPER Study (Patient-Centered Research Into Outcomes Stroke Patients Prefer and Effectiveness Research).” Stroke 47, no. 10 (October 2016): 2627–33. https://doi.org/10.1161/STROKEAHA.116.013563.
    Full Text Link to Item
  - Ahmad, Zahid S., Rolf L. Andersen, Lars H. Andersen, Emily C. O’Brien, Iris Kindt, Peter Shrader, Chandna Vasandani, et al. “US physician practices for diagnosing familial hypercholesterolemia: data from the CASCADE-FH registry.” J Clin Lipidol 10, no. 5 (September 2016): 1223–29. https://doi.org/10.1016/j.jacl.2016.07.011.
    Full Text Link to Item
  - Krishnamoorthy, Arun, Melissa A. Greiner, Alain G. Bertoni, Zubin J. Eapen, Emily C. O’Brien, Lesley H. Curtis, Adrian F. Hernandez, and Robert J. Mentz. “The Obesity and Heart Failure Epidemics Among African Americans: Insights From the Jackson Heart Study.” J Card Fail 22, no. 8 (August 2016): 589–97. https://doi.org/10.1016/j.cardfail.2016.03.004.
    Full Text Link to Item
  - Mentz, Robert J., and Emily C. O’Brien. “Can 2 Pills a Day Keep Readmission Away?: Sacubitril/Valsartan to Reduce 30-Day Heart Failure Readmissions.” J Am Coll Cardiol 68, no. 3 (July 19, 2016): 249–51. https://doi.org/10.1016/j.jacc.2016.05.013.
    Full Text Link to Item
  - Foraker, Randi E., Melissa Greiner, Mario Sims, Katherine L. Tucker, Amytis Towfighi, Aurelian Bidulescu, Abigail B. Shoben, et al. “Comparison of risk scores for the prediction of stroke in African Americans: Findings from the Jackson Heart Study.” Am Heart J 177 (July 2016): 25–32. https://doi.org/10.1016/j.ahj.2016.04.007.
    Full Text Link to Item
  - deGoma, Emil M., Zahid S. Ahmad, Emily C. O’Brien, Iris Kindt, Peter Shrader, Connie B. Newman, Yashashwi Pokharel, et al. “Treatment Gaps in Adults With Heterozygous Familial Hypercholesterolemia in the United States: Data From the CASCADE-FH Registry.” Circ Cardiovasc Genet 9, no. 3 (June 2016): 240–49. https://doi.org/10.1161/CIRCGENETICS.116.001381.
    Full Text Link to Item
  - O’Brien, Emily C., Sunghee Kim, Laine Thomas, Gregg C. Fonarow, Peter R. Kowey, Kenneth W. Mahaffey, Bernard J. Gersh, Jonathan P. Piccini, and Eric D. Peterson. “Clinical Characteristics, Oral Anticoagulation Patterns, and Outcomes of Medicaid Patients With Atrial Fibrillation: Insights From the Outcomes Registry for Better Informed Treatment of Atrial Fibrillation (ORBIT-AF I) Registry.” J Am Heart Assoc 5, no. 5 (May 4, 2016). https://doi.org/10.1161/JAHA.115.002721.
    Full Text Open Access Copy Link to Item
  - Pokorney, Sean D., Emily C. O’Brien, and Christopher B. Granger. “Assessing generalizability of trial results in general practice.” Eur Heart J 37, no. 14 (April 7, 2016): 1154–57. https://doi.org/10.1093/eurheartj/ehv532.
    Full Text Link to Item
  - Fonarow, Gregg C., Li Liang, Laine Thomas, Ying Xian, Jeffrey L. Saver, Eric E. Smith, Lee H. Schwamm, et al. “Assessment of Home-Time After Acute Ischemic Stroke in Medicare Beneficiaries.” Stroke 47, no. 3 (March 2016): 836–42. https://doi.org/10.1161/STROKEAHA.115.011599.
    Full Text Link to Item
  - Mentz, Robert J., Adrian F. Hernandez, Lisa G. Berdan, Tyrus Rorick, Emily C. O’Brien, Jenny C. Ibarra, Lesley H. Curtis, and Eric D. Peterson. “Good Clinical Practice Guidance and Pragmatic Clinical Trials: Balancing the Best of Both Worlds.” Circulation 133, no. 9 (March 1, 2016): 872–80. https://doi.org/10.1161/CIRCULATIONAHA.115.019902.
    Full Text Link to Item
  - O’Brien, Emily C., Jingjing Wu, Phillip J. Schulte, Alexander Christian, Warren Laskey, Deepak L. Bhatt, Eric D. Peterson, Adrian F. Hernandez, and Gregg C. Fonarow. “Statin use, intensity, and 3-year clinical outcomes among older patients with coronary artery disease.” Am Heart J 173 (March 2016): 27–34. https://doi.org/10.1016/j.ahj.2015.11.014.
    Full Text Link to Item
  - O’Brien, Emily C., and Laine E. Thomas. “Untangling the paradox: Obesity as prognostic marker in prevalent cardiovascular disease.” Am Heart J 172 (February 2016): 170–72. https://doi.org/10.1016/j.ahj.2015.11.005.
    Full Text Link to Item
  - Mentz, Robert J., and Emily C. O’Brien. “Air Pollution in Patients With Heart Failure: Lessons From a Mechanistic Pilot Study of a Filter Intervention.” Jacc Heart Fail 4, no. 1 (January 2016): 65–67. https://doi.org/10.1016/j.jchf.2015.11.008.
    Full Text Link to Item
  - O’Brien, Emily C., Michael T. Durheim, Victoria Gamerman, Sandy Garfinkel, Kevin J. Anstrom, Scott M. Palmer, and Craig S. Conoscenti. “Rationale for and design of the Idiopathic Pulmonary Fibrosis-PRospective Outcomes (IPF-PRO) registry.” Bmj Open Respir Res 3, no. 1 (2016): e000108. https://doi.org/10.1136/bmjresp-2015-000108.
    Full Text Link to Item
  - O’Brien, E. C., D. J. N. Simon, L. E. Thomas, E. M. Hylek, B. J. Gersh, J. E. Ansell, P. R. Kowey, et al. “The ORBIT bleeding score: A simple bedside score to assess bleeding risk in atrial fibrillation.” European Heart Journal 36, no. 46 (December 7, 2015): 3258–64. https://doi.org/10.93/eurheartj/ehv476.
    Full Text
  - O’Brien, Emily C., DaJuanicia N. Simon, Laine E. Thomas, Elaine M. Hylek, Bernard J. Gersh, Jack E. Ansell, Peter R. Kowey, et al. “The ORBIT bleeding score: a simple bedside score to assess bleeding risk in atrial fibrillation.” Eur Heart J 36, no. 46 (December 7, 2015): 3258–64. https://doi.org/10.1093/eurheartj/ehv476.
    Full Text Open Access Copy Link to Item
  - O’Brien, Emily C., Melissa A. Greiner, Mario Sims, Natalie Chantelle Hardy, Wei Wang, Eyal Shahar, Adrian F. Hernandez, and Lesley H. Curtis. “Depressive Symptoms and Risk of Cardiovascular Events in Blacks: Findings From the Jackson Heart Study.” Circ Cardiovasc Qual Outcomes 8, no. 6 (November 2015): 552–59. https://doi.org/10.1161/CIRCOUTCOMES.115.001800.
    Full Text Link to Item
  - O’Brien, Emily C., Melissa A. Greiner, Ying Xian, Gregg C. Fonarow, DaiWai M. Olson, Lee H. Schwamm, Deepak L. Bhatt, et al. “Clinical Effectiveness of Statin Therapy After Ischemic Stroke: Primary Results From the Statin Therapeutic Area of the Patient-Centered Research Into Outcomes Stroke Patients Prefer and Effectiveness Research (PROSPER) Study.” Circulation 132, no. 15 (October 13, 2015): 1404–13. https://doi.org/10.1161/CIRCULATIONAHA.115.016183.
    Full Text Link to Item
  - O’Brien, Emily C., Xin Zhao, Gregg C. Fonarow, Phillip J. Schulte, David Dai, Eric E. Smith, Lee H. Schwamm, et al. “Quality of Care and Ischemic Stroke Risk After Hospitalization for Transient Ischemic Attack: Findings From Get With The Guidelines-Stroke.” Circ Cardiovasc Qual Outcomes 8, no. 6 Suppl 3 (October 2015): S117–24. https://doi.org/10.1161/CIRCOUTCOMES.115.002048.
    Full Text Link to Item
  - Shah, Bimal R., Emily C. O’Brien, Matthew T. Roe, Anita Y. Chen, and Eric D. Peterson. “The association of in-hospital guideline adherence and longitudinal postdischarge mortality in older patients with non-ST-segment elevation myocardial infarction.” Am Heart J 170, no. 2 (August 2015): 273-280.e1. https://doi.org/10.1016/j.ahj.2015.05.007.
    Full Text Link to Item
  - Xian, Ying, Jingjing Wu, Emily C. O’Brien, Gregg C. Fonarow, DaiWai M. Olson, Lee H. Schwamm, Deepak L. Bhatt, et al. “Real world effectiveness of warfarin among ischemic stroke patients with atrial fibrillation: observational analysis from Patient-Centered Research into Outcomes Stroke Patients Prefer and Effectiveness Research (PROSPER) study.” Bmj 351 (July 31, 2015): h3786. https://doi.org/10.1136/bmj.h3786.
    Full Text Link to Item
  - Ahmad, Tariq, Emily C. O’Brien, Phillip J. Schulte, Susanna R. Stevens, Mona Fiuzat, Dalane W. Kitzman, Kirkwood F. Adams, et al. “Evaluation of the Incremental Prognostic Utility of Increasingly Complex Testing in Chronic Heart Failure.” Circ Heart Fail 8, no. 4 (July 2015): 709–16. https://doi.org/10.1161/CIRCHEARTFAILURE.114.001996.
    Full Text Link to Item
  - O’Brien, Emily C., Lisa A. McCoy, Laine Thomas, Eric D. Peterson, and Tracy Y. Wang. “Patient adherence to generic versus brand statin therapy after acute myocardial infarction: Insights from the Can Rapid Stratification of Unstable Angina Patients Suppress Adverse Outcomes with Early Implementation of the American College of Cardiology/American Heart Association Guidelines Registry.” Am Heart J 170, no. 1 (July 2015): 55–61. https://doi.org/10.1016/j.ahj.2015.04.011.
    Full Text Link to Item
  - Xian, Ying, Emily C. O’Brien, Gregg C. Fonarow, DaiWai M. Olson, Lee H. Schwamm, Deidre Hannah, Brianna Lindholm, et al. “Patient-Centered Research into Outcomes Stroke Patients Prefer and Effectiveness Research: Implementing the patient-driven research paradigm to aid decision making in stroke care.” Am Heart J 170, no. 1 (July 2015): 36-45.11. https://doi.org/10.1016/j.ahj.2015.04.008.
    Full Text Link to Item
  - O’Brien, Emily C., DaJuanicia N. Simon, Matthew T. Roe, Tracy Y. Wang, Eric D. Peterson, and Karen P. Alexander. “Statin Treatment by Low-Density Lipoprotein Cholesterol Levels in Patients With Non-ST-Segment Elevation Myocardial Infarction/Unstable Angina Pectoris (from the CRUSADE Registry).” Am J Cardiol 115, no. 12 (June 15, 2015): 1655–60. https://doi.org/10.1016/j.amjcard.2015.03.007.
    Full Text Link to Item
  - O’Brien, Emily C., Sunghee Kim, Paul L. Hess, Peter R. Kowey, Gregg C. Fonarow, Jonathan P. Piccini, and Eric D. Peterson. “Effect of the 2014 atrial fibrillation guideline revisions on the proportion of patients recommended for oral anticoagulation.” Jama Intern Med 175, no. 5 (May 2015): 848–50. https://doi.org/10.1001/jamainternmed.2015.13.
    Full Text Link to Item
  - Mentz, Robert J., Melissa A. Greiner, Adam D. DeVore, Shannon M. Dunlay, Gaurav Choudhary, Tariq Ahmad, Prateeti Khazanie, et al. “Ventricular conduction and long-term heart failure outcomes and mortality in African Americans: insights from the Jackson Heart Study.” Circ Heart Fail 8, no. 2 (March 2015): 243–51. https://doi.org/10.1161/CIRCHEARTFAILURE.114.001729.
    Full Text Open Access Copy Link to Item
  - Ahmad, Tariq, Teresa Wang, Emily C. O’Brien, Marc D. Samsky, John A. Pura, Yuliya Lokhnygina, Joseph G. Rogers, et al. “Effects of left ventricular assist device support on biomarkers of cardiovascular stress, fibrosis, fluid homeostasis, inflammation, and renal injury.” Jacc Heart Fail 3, no. 1 (January 2015): 30–39. https://doi.org/10.1016/j.jchf.2014.06.013.
    Full Text Link to Item
  - Ahmad, Tariq, Teresa Wang, Emily C. O’Brien, Marc D. Samsky, John A. Pura, Yuliya Lokhnygina, Joseph G. Rogers, et al. “Effects of Left Ventricular Assist Device Support on Biomarkers of Cardiovascular Stress, Fibrosis, Fluid Homeostasis, Inflammation, and Renal Injury.” Jacc Heart Failure 3, no. 1 (January 2015): 30–39. https://doi.org/10.1016/j.jchf.2014.06.013.
    Full Text Link to Item
  - Knowles, Joshua W., Emily C. O’Brien, Karen Greendale, Katherine Wilemon, Jacques Genest, Laurence S. Sperling, William A. Neal, Daniel J. Rader, and Muin J. Khoury. “Reducing the burden of disease and death from familial hypercholesterolemia: a call to action.” Am Heart J 168, no. 6 (December 2014): 807–11. https://doi.org/10.1016/j.ahj.2014.09.001.
    Full Text Link to Item
  - Kuntz, Jennifer L., Monika M. Safford, Jasvinder A. Singh, Shobha Phansalkar, Sarah P. Slight, Qoua Liang Her, Nancy Allen Lapointe, et al. “Patient-centered interventions to improve medication management and adherence: a qualitative review of research findings.” Patient Educ Couns 97, no. 3 (December 2014): 310–26. https://doi.org/10.1016/j.pec.2014.08.021.
    Full Text Link to Item
  - O’Brien, Emily C., Sunghee Kim, Paul L. Hess, James V. Freeman, Laine Thomas, Gregg C. Fonarow, Jack E. Ansell, et al. “Impact of the 2014 Atrial Fibrillation Guideline on the Proportion of Patients Recommended for Oral Anticoagulation.” Circulation 130 (November 25, 2014).
    Link to Item
  - O’Brien, Emily C., Ying Xian, Gregg C. Fonarow, DaiWai M. Olson, Lee H. Schwamm, and Adrian F. Hernandez. “Clinical commentary on "Certain uncertainty: life after stroke from the patient's perspective".” Circ Cardiovasc Qual Outcomes 7, no. 6 (November 2014): 970. https://doi.org/10.1161/CIRCOUTCOMES.114.001484.
    Full Text Link to Item
  - Ahmad, Tariq, Michael J. Pencina, Phillip J. Schulte, Emily O’Brien, David J. Whellan, Ileana L. Piña, Dalane W. Kitzman, Kerry L. Lee, Christopher M. O’Connor, and G Michael Felker. “Clinical implications of chronic heart failure phenotypes defined by cluster analysis.” J Am Coll Cardiol 64, no. 17 (October 28, 2014): 1765–74. https://doi.org/10.1016/j.jacc.2014.07.979.
    Full Text Link to Item
  - O’Brien, Emily C., DaJuanicia N. Simon, Larry A. Allen, Daniel E. Singer, Gregg C. Fonarow, Peter R. Kowey, Laine E. Thomas, et al. “Reasons for warfarin discontinuation in the Outcomes Registry for Better Informed Treatment of Atrial Fibrillation (ORBIT-AF).” Am Heart J 168, no. 4 (October 2014): 487–94. https://doi.org/10.1016/j.ahj.2014.07.002.
    Full Text Link to Item
  - O’Brien, Emily, Sumeet Subherwal, Matthew T. Roe, DaJuanicia N. Holmes, Laine Thomas, Karen P. Alexander, Tracy Y. Wang, and Eric D. Peterson. “Do patients treated at academic hospitals have better longitudinal outcomes after admission for non-ST-elevation myocardial infarction?” Am Heart J 167, no. 5 (May 2014): 762–69. https://doi.org/10.1016/j.ahj.2014.01.009.
    Full Text Link to Item
  - Johnson, Anna M., Larry B. Goldstein, Paige Bennett, Emily C. O’Brien, Wayne D. Rosamond, and Wayne D. investigators of the Registry of the North Carolina Stroke Care Collaborative. “Compliance with acute stroke care quality measures in hospitals with and without primary stroke center certification: the North Carolina Stroke Care Collaborative.” J Am Heart Assoc 3, no. 2 (April 10, 2014): e000423. https://doi.org/10.1161/JAHA.113.000423.
    Full Text Link to Item
  - O’Brien, Emily C., DaJuanicia N. Holmes, Jack E. Ansell, Larry A. Allen, Elaine Hylek, Peter R. Kowey, Bernard J. Gersh, et al. “Physician practices regarding contraindications to oral anticoagulation in atrial fibrillation: findings from the Outcomes Registry for Better Informed Treatment of Atrial Fibrillation (ORBIT-AF) registry.” Am Heart J 167, no. 4 (April 2014): 601-609.e1. https://doi.org/10.1016/j.ahj.2013.12.014.
    Full Text Link to Item
  - O’Brien, Emily C., Matthew T. Roe, Elizabeth S. Fraulo, Eric D. Peterson, Christie M. Ballantyne, Jacques Genest, Samuel S. Gidding, et al. “Rationale and design of the familial hypercholesterolemia foundation CAscade SCreening for Awareness and DEtection of Familial Hypercholesterolemia registry.” Am Heart J 167, no. 3 (March 2014): 342-349.e17. https://doi.org/10.1016/j.ahj.2013.12.008.
    Full Text Link to Item
  - O’Brien, E. C., M. T. Roe, E. S. Fraulo, E. D. Peterson, C. M. Ballantyne, J. Genest, S. S. Gidding, et al. “Rationale and design of the familial hypercholesterolemia foundation CAscade SCreening for Awareness and DEtection of Familial Hypercholesterolemia registry.” American Heart Journal 167, no. 3 (2014): 342-349.e17.
  - O’Brien, Emily C., Emil L. Fosbol, S Andrew Peng, Karen P. Alexander, Matthew T. Roe, and Eric D. Peterson. “Association of body mass index and long-term outcomes in older patients with non-ST-segment-elevation myocardial infarction: results from the CRUSADE Registry.” Circ Cardiovasc Qual Outcomes 7, no. 1 (January 2014): 102–9. https://doi.org/10.1161/CIRCOUTCOMES.113.000421.
    Full Text Link to Item
  - O’Brien, Emily C., Kathryn M. Rose, Chirayath M. Suchindran, Til Stürmer, Patricia P. Chang, Lloyd Chambless, Cameron S. Guild, and Wayne D. Rosamond. “Medication, reperfusion therapy and survival in a community-based setting of hospitalised myocardial infarction.” Heart 99, no. 11 (June 2013): 767–73. https://doi.org/10.1136/heartjnl-2012-303244.
    Full Text Link to Item
  - O’Brien, Emily C., Kathryn M. Rose, Chirayath M. Suchindran, Til Sturmer, Patricia P. Chang, Alvaro Alonso, Christopher D. Baggett, and Wayne D. Rosamond. “Temporal trends in medical therapies for ST- and non-ST elevation myocardial infarction: (from the Atherosclerosis Risk in Communities [ARIC] Surveillance Study).” Am J Cardiol 111, no. 3 (February 1, 2013): 305–11. https://doi.org/10.1016/j.amjcard.2012.09.032.
    Full Text Link to Item
  - Rosamond, Wayne, Anna Johnson, Paige Bennett, Emily O’Brien, Laurie Mettam, Sara Jones, and Sylvia Coleman. “Monitoring and improving acute stroke care: The North Carolina Stroke Care Collaborative.” N C Med J 73, no. 6 (November 2012): 494–98.
    Link to Item
  - O’Brien, Emily C., Kathryn M. Rose, Mehul D. Patel, Carol V. Murphy, and Wayne D. Rosamond. “Clinical outcomes among stroke patients receiving tissue plasminogen activator therapy beyond the 3-hour time window.” J Stroke Cerebrovasc Dis 21, no. 7 (October 2012): 541–46. https://doi.org/10.1016/j.jstrokecerebrovasdis.2010.12.004.
    Full Text Link to Item
  - Patel, Mehul D., Kathryn M. Rose, Emily C. O’Brien, and Wayne D. Rosamond. “Prehospital notification by emergency medical services reduces delays in stroke evaluation: findings from the North Carolina stroke care collaborative.” Stroke 42, no. 8 (August 2011): 2263–68. https://doi.org/10.1161/STROKEAHA.110.605857.
    Full Text Link to Item
  - O’Brien, Emily C., Kathryn M. Rose, Eyal Shahar, and Wayne D. Rosamond. “Stroke Mortality, Clinical Presentation and Day of Arrival: The Atherosclerosis Risk in Communities (ARIC) Study.” Stroke Res Treat 2011 (2011): 383012. https://doi.org/10.4061/2011/383012.
    Full Text Link to Item
  - Mears, Greg D., Wayne D. Rosamond, Chad Lohmeier, Carol Murphy, Emily O’Brien, Andrew W. Asimos, and Jane H. Brice. “A link to improve stroke patient care: a successful linkage between a statewide emergency medical services data system and a stroke registry.” Acad Emerg Med 17, no. 12 (December 2010): 1398–1404. https://doi.org/10.1111/j.1553-2712.2010.00925.x.
    Full Text Link to Item
  - Wang, Teresa, Emily C. O’Brien, Joseph G. Rogers, Daniel L. Jacoby, Michael E. Chen, Jeffrey M. Testani, Dawn E. Bowles, et al. “Plasma Levels of MicroRNA-155 Are Upregulated with Long-Term Left Ventricular Assist Device Support.” Asaio J 63, no. 5 (n.d.): 536–41. https://doi.org/10.1097/MAT.0000000000000564.
    Full Text Link to Item
- Conference Papers
  - Swaminathan, Aparna, Emily O’Brien, Anne Hellkamp, Megan Neely, Shaun Bender, Laurie Snyder, Daniel Culver, et al. “HEALTH-RELATED QUALITY OF LIFE MEASURES IN IDIOPATHIC PULMONARY FIBROSIS: DATA FROM THE IPF-PRO REGISTRY.” In Chest, 156:A180–81. Elsevier BV, 2019. https://doi.org/10.1016/j.chest.2019.08.248.
    Full Text
  - Luo, Nancy, Nicholas G. Ballew, Emily O’Brien, Melissa Greiner, Pamela Peterson, Bradley Hammill, N Chantelle Hardy, et al. “EARLY IMPACT OF GUIDELINE PUBLICATION ON ANGIOTENSIN-RECEPTOR NEPRILYSIN INHIBITOR USE AMONG PATIENTS HOSPITALIZED FOR HEART FAILURE.” In Journal of the American College of Cardiology, 71:A791–A791. Elsevier BV, 2018. https://doi.org/10.1016/s0735-1097(18)31332-9.
    Full Text
  - Shah, Shreyansh, Haolin Xu, Ying Xian, Lesley Maisch, Deidre Hannah, Brianna Lindholm, Barbara L. Lytie, et al. “Patterns of Discharge Antidepressant Therapy Use After Acute Ischemic Stroke: Insights From the Prosper Study.” In Stroke, Vol. 49. LIPPINCOTT WILLIAMS & WILKINS, 2018.
    Link to Item
  - Greene, Stephen, Nancy Luo, Robert J. Mentz, Chantelle Hardy, Warren K. Laskey, Paul A. Heidenreich, Clyde W. Yancy, et al. “Home-Time as a Novel Post-Discharge Outcome for Patients Hospitalized With Heart Failure.” In Circulation, Vol. 136. LIPPINCOTT WILLIAMS & WILKINS, 2017.
    Link to Item
  - Sharma, Abhinav, Adrian F. Hernandez, Pearl Zakroysky, Melissa Hamilton, and Emily C. O’Brien. “Eliminate Thromboembolism: Improving Anticoagulation in Non-Valvular Atrial Fibrillation Patients' (ELITE) Registry - Insights From the Baseline Results.” In Circulation, Vol. 136. LIPPINCOTT WILLIAMS & WILKINS, 2017.
    Link to Item
  - O’Brien, Emily, Diane Bloom, Carol Koro, Jamie Lorimer, Sudha R. Raman, Robert J. Mentz, Bradley G. Hammill, Lisa G. Berdan, Ty Rorick, and Salim Janmohamed. “Perceptions of the utility and barriers of using electronic health records for patient screening in clinical trials: an in-depth interviews study of site coordinators.” In Trials, Vol. 18. BIOMED CENTRAL LTD, 2017.
    Link to Item
  - O’Brien, Emily Claire, DaJuanicia Simon, Laine Thomas, Daniel Singer, Peter Kowey, Gerald Naccarelli, Gregg Fonarow, et al. “NUISANCE BLEEDING IN ANTICOAGULATED PATIENTS WITH ATRIAL FIBRILLATION: INSIGHTS FROM THE OUTCOMES REGISTRY FOR BETTER INFORMED TREATMENT OF ATRIAL FIBRILLATION (ORBIT-AF).” In Journal of the American College of Cardiology, 69:536–536. ELSEVIER SCIENCE INC, 2017.
    Link to Item
  - Leonard, T., E. C. O’Brien, V. Gamerman, E. Yow, M. L. Neely, C. S. Conoscenti, and D. A. Culver. “Composite Physiologic Index (cpi) Categorization And Gender Age Physiology (gap) Stage Correlation And Differentiation Of Patient-Reported Health-Related Quality Of Life In Patients With Idiopathic Pulmonary Fibrosis (ipf).” In American Journal of Respiratory and Critical Care Medicine, Vol. 195. AMER THORACIC SOC, 2017.
    Link to Item
  - Pokorney, Sean, Richard Platt, Lisa Ortendahl, Tiffany Woodworth, Noelle Cocoros, Cheryl Walraven, Jeffrey Brown, et al. “LOW USE OF ORAL ANTICOAGULATION IN PATIENTS WITH ATRIAL FIBRILLATION AND RISK FOR STROKE IN THE UNITED STATES.” In Journal of the American College of Cardiology, 67:886–886. Elsevier BV, 2016. https://doi.org/10.1016/s0735-1097(16)30887-7.
    Full Text
  - Steinberg, Benjamin, Peter Shrader, Laine Thomas, Gregg Fonarow, Elaine Hylek, Jack Ansell, Peter Kowey, et al. “ORAL ANTICOAGULANT SELECTION IN COMMUNITY PATIENTS WITH NEW-ONSET ATRIAL FIBRILLATION: RESULTS FROM THE ORBIT-AF II REGISTRY.” In Journal of the American College of Cardiology, 67:885–885. Elsevier BV, 2016. https://doi.org/10.1016/s0735-1097(16)30886-5.
    Full Text
  - Fonarow, Gregg C., Li Liang, Laine Thomas, Ying Xian, Jeffrey L. Saver, Eric E. Smith, Lee H. Schwamm, et al. “Assessment of Home Time Following Acute Ischemic Stroke in Medicare Beneficiaries.” In Stroke, Vol. 47. LIPPINCOTT WILLIAMS & WILKINS, 2016.
    Link to Item
  - O’Brien, E. C., P. Shrader, M. T. Durheim, L. D. Snyder, J. L. Todd, V. Gamerman, K. J. Anstrom, et al. “Disease Severity And Quality Of Life In Newly Diagnosed Idiopathic Pulmonary Fibrosis Patients.” In American Journal of Respiratory and Critical Care Medicine, Vol. 193. AMER THORACIC SOC, 2016.
    Link to Item
  - O’Brien, Emily C., DaJuanicia N. Simon, Laine Thomas, Gregg C. Fonarow, Peter R. Kowey, Kenneth W. Mahaffey, Jonathan P. Piccini, and Eric D. Peterson. “Comparative Performance of the R(2)Chads(2), Chads(2), and Cha(2)Ds(2)-vasc Scores in Atrial Fibrillation.” In Circulation, Vol. 132. LIPPINCOTT WILLIAMS & WILKINS, 2015.
    Link to Item
  - Randolph, Tiffany C., Melissa A. Greiner, Chidiebube Egwim, Adrian F. Hernandez, Kevin L. Thomas, Lesley H. Curtis, Paul Muntner, Wei Wang, Robert J. Mentz, and Emily C. O’Brien. “The Association Between Blood Pressure Control and Outcomes Among Black Participants in the Jackson Heart Study.” In Circulation, Vol. 132. LIPPINCOTT WILLIAMS & WILKINS, 2015.
    Link to Item
  - Durheim, Michael, Emily O’Brien, Victoria Gamerman, Jamie Todd, Laurie Snyder, Kevin Anstrom, Scott Palmer, and Craig Conoscenti. “Newly Diagnosed IPF at Tertiary Care Pulmonary Centers: Initial Results From the Idiopathic Pulmonary Fibrosis — PROspective Outcomes (IPF-PRO) Registry.” In Chest, 148:362A-362A. Elsevier BV, 2015. https://doi.org/10.1378/chest.2268509.
    Full Text
  - O’Brien, Emily Claire, Emil DeGoma, Patrick Moriarty, MacRae F. Linton, Michael Shapiro, Bart Duell, Christie Ballantyne, et al. “INITIAL RESULTS FROM THE CASCADE-FH REGISTRY: CASCADE SCREENING FOR AWARENESS AND DETECTION OF FAMILIAL HYPERCHOLESTEROLEMIA.” In Journal of the American College of Cardiology, 65:A1372–A1372. Elsevier BV, 2015. https://doi.org/10.1016/s0735-1097(15)61372-9.
    Full Text
  - Greiner, Melissa A., Emily O’Brien, Ying Xian, Deepak L. Bhatt, Lesley Maisch, Deidre Hannah, Brianna Lindholm, et al. “High vs. Moderate-intensity Statin Therapy After Ischemic Stroke: Findings from PROSPER.” In Stroke, Vol. 46. LIPPINCOTT WILLIAMS & WILKINS, 2015.
    Link to Item
  - O’Brien, Emily C., Jingjing Wu, Phillip J. Schulte, Gregg C. Fonarow, Adrian F. Hernandez, Lee H. Schwamm, Eric D. Peterson, Deepak L. Bhatt, and Eric E. Smith. “Healthcare Resource Availability, Acute Ischemic Stroke Outcomes and Quality of Care.” In Stroke, Vol. 46. LIPPINCOTT WILLIAMS & WILKINS, 2015.
    Link to Item
  - O’Brien, Emily C., Melissa A. Greiner, Eyal Shahar, N Chantelle Hardy, Mario Sims, Wei Wang, Adrian F. Hernandez, and Lesley H. Curtis. “Depressive Symptoms and Risk of Stroke in African Americans: Findings from the Jackson Heart Study.” In Stroke, Vol. 46. LIPPINCOTT WILLIAMS & WILKINS, 2015.
    Link to Item
  - O’Brien, Emily C., Melissa A. Greiner, Ying Xian, Gregg C. Fonarow, DaiWai M. Olson, Lee H. Schwamm, Deepak L. Bhatt, et al. “Clinical Effectiveness of Statin Therapy after Ischemic Stroke: Primary Results from the PROSPER Study.” In Stroke, Vol. 46. LIPPINCOTT WILLIAMS & WILKINS, 2015.
    Link to Item
  - Xian, Ying, Jingjing Wu, Emily C. O’Brien, Gregg C. Fonarow, DaiWai M. Olson, Lee H. Schwamm, Deepak L. Bhatt, et al. “Clinical Effectiveness of Anticoagulation with Warfarin among Ischemic Stroke Patients with Atrial Fibrillation: Findings from the Patient-Centered Research into Outcomes Stroke Patients Prefer and Effectiveness Research (PROSPER) Study.” In Stroke, Vol. 46. LIPPINCOTT WILLIAMS & WILKINS, 2015.
    Link to Item
  - Mentz, Robert J., Melissa A. Greiner, Adam D. DeVore, Shannon M. Dunlay, Gaurav Choudhary, Prateeti Khazanie, Tariq Ahmad, et al. “Ventricular Conduction and Long-term Outcomes in African Americans: Insights from the Jackson Heart Study.” In Circulation, Vol. 130. LIPPINCOTT WILLIAMS & WILKINS, 2014.
    Link to Item
  - O’Brien, Emily C., Jingjing Wu, Phillip Schulte, Alexander Christian, Deepak L. Bhatt, Warren K. Laskey, Adrian F. Hernandez, and Gregg C. Fonarow. “High versus Low-to-Moderate Intensity Statin Treatment and One -Year Clinical Outcomes Among Older Patients With Coronary Artery Disease.” In Circulation, Vol. 130. LIPPINCOTT WILLIAMS & WILKINS, 2014.
    Link to Item
  - Wang, Teresa, Emily O’Brien, Marc Samsky, Joseph Rogers, Adrian Hernandez, Dawn Bowles, G Michael Felker, Chetan Patel, and Tariq Ahmad. “Effects of Left Ventricular Assist Device Support on microRNA Levels.” In Circulation, Vol. 130. LIPPINCOTT WILLIAMS & WILKINS, 2014.
    Link to Item
  - O’Brien, Emily C., Dajuanlca N. Holmes, Matthew T. Roe, Eric D. Peterson, and Karen S. Alexander. “Treatment and Outcomes by LDL-C Level in Statin-Naive Non-ST-Elevation Myocardial Infarction (NSTEMI) Patients: Findings From the CRUSADE Registry.” In Circulation, Vol. 128. LIPPINCOTT WILLIAMS & WILKINS, 2013.
    Link to Item
  - O’Brien, Emily C., Xin Zhao, Gregg C. Fonarow, Eric E. Smith, Lee H. Schwamm, Deepak L. Bhatt, Ying Xian, et al. “Readmission for Stroke and Quality of Care Among Patients Hospitalized With Transient Ischemic Attack (TIA): Findings From Get With the Guidelines (GWTG)-Stroke.” In Circulation, Vol. 128. LIPPINCOTT WILLIAMS & WILKINS, 2013.
    Link to Item
Teaching & Mentoring
Recent Courses
- CRP 247: Clinical Research Seminar 2020
- POPHS 701: Applied Analytic Methods for Population Health Sciences I 2019

Some information on this profile has been compiled automatically from Duke databases and external sources. (Our About page explains how this works.) If you see a problem with the information, please write to Scholars@Duke and let us know. We will reply promptly.

Education, Training, & Certifications

Duke Appointment History

In the News

Selected Grants

Selected Publications

Academic Articles

Conference Papers

Recent Courses