Eric Monson

Journal article Bull Math Biol · January 2013 A long-standing paradigm in B cell immunology is that effective somatic hypermutation and affinity maturation require cycling between the dark zone and light zone of the germinal center. The cyclic re-entry hypothesis was first proposed based on considerat ... Full text Link to item Cite

Data representation and exploration with geometric wavelets

Journal article Vast 10 IEEE Conference on Visual Analytics Science and Technology 2010 Proceedings · December 1, 2010 Geometric Wavelets is a new multi-scale data representation technique which is useful for a variety of applications such as data compression, interpretation and anomaly detection. We have developed an interactive visualization with multiple linked views to ... Full text Cite

On spiking models for synaptic activity and impulsive differential equations

Journal article SIAM Review · September 1, 2008 We illustrate the problems that can arise in writing differential equations that include Dirac delta functions to model equations with state-dependent impulsive forcing. Specifically, difficulties arise in the interpretation of the products of distribution ... Full text Cite

Polarized secretory trafficking directs cargo for asymmetric dendrite growth and morphogenesis.

Journal article Neuron · December 2005 Proper growth of dendrites is critical to the formation of neuronal circuits, but the cellular machinery that directs the addition of membrane components to generate dendritic architecture remains obscure. Here, we demonstrate that post-Golgi membrane traf ... Full text Cite

Nonclassical kinetics of an elementary A+B-->C reaction-diffusion system showing effects of a speckled initial reactant distribution and eventual self-segregation: experiments.

Journal article Physical review. E, Statistical, nonlinear, and soft matter physics · February 2004 We demonstrate here the implementation of an experimental system suitable for the study of the diffusion limited A+B-->0, nonclassical reaction behavior. Using a combination of a fluorescent calcium indicator and a calcium ion which is initially "caged," a ... Full text Cite

Room-temperature preparation and characterization of poly (ethylene glycol)-coated silica nanoparticles for biomedical applications.

Journal article Journal of biomedical materials research. Part A · September 2003 Monodisperse, spherical, polyethylene glycol (PEG)-coated silica nanoparticles have been prepared at room temperature and characterized for the purpose of biomedical applications. The particles were synthesized by the hydrolysis of tetramethyl orthosilicat ... Full text Cite

A fluorescent PEBBLE nanosensor for intracellular free zinc.

Journal article The Analyst · January 2002 The development and characterisation of a fluorescent optical PEBBLE (Probe Encapsulated By Biologically Localised Embedding) nanosensor for the detection of zinc is detailed. A ratiometric sensor has been fabricated that incorporates two fluorescent dyes; ... Full text Cite

Observation of laser speckle effects and nonclassical kinetics in an elementary chemical reaction.

Journal article Physical review letters · July 2000 An experimental demonstration is provided for memory-based, nonclassical reaction kinetics in a homogeneous system with an elementary reaction, A+B-->C. A new reaction-kinetics regime is observed which is a direct consequence of speckles in the laser beam. ... Full text Cite

A compact fluorescence and polarization near-field scanning optical microscope

Journal article Review of Scientific Instruments · January 1, 1998 We present a transmission, fluorescence, and polarization near-field scanning optical microscope with shear-force feedback control that is small in size and simple to operate. This microscope features an ultrafine mechanical tip/sample approach with contin ... Full text Cite

Nonclassical dimension-dependent kinetics of a photobleaching reaction in a focused laser beam “phototrap”

Journal article Physical Review E Statistical Physics Plasmas Fluids and Related Interdisciplinary Topics · January 1, 1997 A focused laser beam acts as both a “phototrap”, bleaching fluorophore molecules that diffuse into the beam path, and as a confocal probe, detecting the excited, unbleached fluorophore molecules still present in the trap. With this focused laser beam, we o ... Full text Cite

Lifetime enhancement of ultrasmall fluorescent liquid polymeric film based optodes by diffusion-induced self-recovery after photobleaching.

Journal article Analytical chemistry · November 1996 The major concern with optodes, especially miniaturized ones, has been their photobleaching limited lifetime. Liquid polymer [highly plasticized poly(vinyl chloride)] films are commonly used to prepare fluorescent optical fiber sensors. A major advantage i ... Full text Cite

ULTRA-SMALL FIBEROPTIC CHEMICAL AND BIOCHEMICAL SENSORS

Journal article ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY · August 20, 1995 Link to item Cite

Implementation of an NSOM system for fluorescence microscopy.

Journal article Ultramicroscopy · February 1995 We describe our progress toward an NSOM system intended for fluorescence imaging of biological samples. This process included integration of shear-force feedback into an existing NSOM system. Topographic images acquired using uncoated tips are presented. W ... Full text Cite