Scholars@Duke
Erin Lin Manning

Erin Lin Manning

Assistant Professor of Anesthesiology
Anesthesiology, Regional

Scholarly Works - Journal articles

Incidence of transient neurologic symptoms in patients receiving lidocaine spinal anesthesia for outpatient joint arthroplasty.

Journal article Reg Anesth Pain Med · May 5, 2026 BACKGROUND: Spinal anesthesia is commonly administered for lower limb total joint arthroplasty, but the prolonged motor and sympathetic block associated with bupivacaine can delay recovery. In contrast, lidocaine, with its swift onset and intermediate dura ... Full text Link to item Cite

Diaphragmatic Ultrasound in Adults: Image Acquisition and Interpretation.

Journal article J Vis Exp · January 31, 2025 Diaphragm dysfunction is a widely recognized concern across numerous medical specialties and clinical settings. Timely and accurate assessment of the diaphragm is vital not only in critically ill patients, where it has a role in weaning from mechanical ven ... Full text Link to item Cite

Perioperative Analgesia in Spine Surgery: A Review of Current Data Supporting Future Direction.

Journal article Orthop Clin North Am · October 2023 This Clinical Research discusses the diverse nature of spine surgery procedures and the use of multimodal analgesia within enhanced recovery after surgery (ERAS) protocols to improve patient outcomes. Spine surgeries range from minor decompressions to exte ... Full text Link to item Cite

THE EFFECTS OF PERIOPERATIVE DEXAMETHASONE ON GLYCEMIC CONTROL AND POSTOPERATIVE OUTCOMES.

Journal article Endocr Pract · February 2020 Objective: Perioperative glucocorticoids are commonly given to reduce pain and nausea in patients undergoing surgery. However, the glycemic effects of steroids and the potential effects on morbidity and mortality have not been systematically evaluated. Thi ... Full text Link to item Cite

A Smartphone-based Decision Support Tool Improves Test Performance Concerning Application of the Guidelines for Managing Regional Anesthesia in the Patient Receiving Antithrombotic or Thrombolytic Therapy.

Journal article Anesthesiology · January 2016 BACKGROUND: The American Society of Regional Anesthesia and Pain Medicine (ASRA) consensus statement on regional anesthesia in the patient receiving antithrombotic or thrombolytic therapy is the standard for evaluation and management of these patients. The ... Full text Link to item Cite

Packed red blood cells suppress T-cell proliferation through a process involving cell-cell contact.

Journal article J Trauma · August 2010 BACKGROUND: Packed red blood cell (PRBC) transfusion suppresses immunity and increases morbidity and mortality. Leukocyte reduction has failed to abrogate these effects, thus implicating red blood cells themselves or their components. PRBC impair prolifera ... Full text Link to item Cite

Red blood cell arginase suppresses Jurkat (T cell) proliferation by depleting arginine.

Journal article Surgery · February 2008 BACKGROUND: Transfusion of packed red blood cells (PRBC) suppresses immunity, but the mechanisms are incompletely understood. PRBCs contain arginase, an enzyme which converts arginine to ornithine and depletes arginine in vitro. Arginine depletion suppress ... Full text Link to item Cite

Influences of inbreeding and genetics on telomere length in mice.

Journal article Mamm Genome · May 2002 We measured telomere lengths of blood leukocytes in several inbred and outbred mammalian species, using a telomere-specific fluorescent probe and flow cytometry. Humans, non-human primates, and three outbred populations of Peromyscus mice ( Peromyscus leuc ... Full text Link to item Cite

Effect of age and replicative stress on hematopoietic stem cell telomere length

Journal article Blood · December 1, 2000 Telomeres and telomerase expression have been implicated in neoplastic progress Ion of human tumors and in replicative senescence of cultured cells. However, their rol& in replicative senescence and aging of cell populations in vivo is less certain. Given ... Cite

Hematopoietic stem cells.

Journal article Clin Orthop Relat Res · October 2000 Hematopoietic stem cells are rare cells found in the bone marrow, peripheral blood, placenta, and elsewhere that sustain the hematopoietic system. The current review will focus on the evolving views of the biology of these cells. Because hematopoietic stem ... Full text Link to item Cite

Critical decline in fine motor hand movements in human aging.

Journal article Neurology · October 22, 1999 BACKGROUND: Slowing of motor movements in human aging is a well-known occurrence, but its biologic basis is poorly understood. Reliable quantitation may refine observations of this phenomenon to better aid research on this entity. METHODS: A panel equipped ... Full text Link to item Cite