Overview
Eugene John Vaios, MD, MBA, is an NIH-funded Assistant Professor of Radiation Oncology at the Duke Cancer Institute. He was previously at Harvard University where he completed his undergraduate and graduate education, as well as his internship at Cambridge Health Alliance. Eugene's research focus is at the intersection of radiation therapy and immunotherapy for patients with primary and metastatic brain tumors. Active translational research includes the development of a liquid biopsy for non-invasive diagnosis, surveillance, and prediction of treatment response in patients with brain tumors. Other interests include leveraging artificial intelligence and big data to improve cancer outcomes. Outside Duke, Eugene holds leadership positions on the ASTRO Board Finance and Audit Committee and serves on the Lancet Commission on Neurorehabilitation.
Current Appointments & Affiliations
Recent Publications
Seizure risk factors and management approaches in patients with brain metastases.
Journal Article Neurooncol Pract · June 2025 A significant proportion of patients with brain metastases experience a seizure event during their disease course, which can impact morbidity and long-term outcomes. A host of factors elevate the risk for seizures in patients with brain metastases, includi ... Full text Link to item CiteTotal brain dose estimation in single-isocenter-multiple-targets (SIMT) radiosurgery via a novel deep neural network with spherical convolutions.
Journal Article Med Phys · June 2025 BACKGROUND AND PURPOSE: Accurate prediction of normal brain dosimetric parameters is crucial for the quality control of single-isocenter multi-target (SIMT) stereotactic radiosurgery (SRS) treatment planning. Reliable dose estimation of normal brain tissue ... Full text Link to item CiteImproved Survival and Prognostication in Melanoma Patients With Brain Metastases: An Update of the Melanoma Graded Prognostic Assessment.
Journal Article J Clin Oncol · June 2025 PURPOSE: Survival for patients with melanoma has recently improved. The propensity of melanoma to metastasize to the brain remains a common and serious feature of this disease. The purposes of this study were to evaluate prognostic factors for patients wit ... Full text Link to item CiteRecent Grants
Elucidating Brain Tumor Biology and Response to Radiotherapy Using Cell-Free-DNA Methylation Signatures
ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2024 - 2026View All Grants