Scholars@Duke
Evan Robert Myers

Evan Robert Myers

Walter L. Thomas Distinguished Professor of Obstetrics and Gynecology in the School of Medicine
Obstetrics and Gynecology, Women's Community & Population Health
Box 3279 Med Ctr, Durham, NC 27710
244 Baker House, Durham, NC 27710

Featured Works

Clomiphene, metformin, or both for infertility in the polycystic ovary syndrome.

Journal article N Engl J Med · February 8, 2007 Featured Publication BACKGROUND: The polycystic ovary syndrome is a common cause of infertility. Clomiphene and insulin sensitizers are used alone and in combination to induce ovulation, but it is unknown whether one approach is superior. METHODS: We randomly assigned 626 infe ... Full text Link to item Cite

Utility of screening for other causes of infertility in women with "known" polycystic ovary syndrome.

Journal article Fertil Steril · February 2007 Featured Publication We investigated the prevalence of abnormal screening results (questionnaire and testing for other causes of oligo-ovulation, male or tubal factor infertility) in a group of 1,313 oligo-ovulatory women (included and excluded subjects) whose condition was sc ... Full text Link to item Cite

Health care resource use for uterine fibroid tumors in the United States.

Journal article Am J Obstet Gynecol · October 2006 Featured Publication OBJECTIVE: The purpose of this study was to quantify the total direct cost to the US health care system for the management of uterine leiomyomas. STUDY DESIGN: We used Center for Disease Control heath care databases for estimates of inpatient care, ambulat ... Full text Link to item Cite

Cost-effectiveness analysis of liquid-based cytology and human papillomavirus testing in cervical cancer screening.

Journal article Obstet Gynecol · May 2006 Featured Publication OBJECTIVE: To compare the outcomes of several cervix cancer screening strategies in a military population using a model that considers both direct and indirect costs of health care. METHODS: A Markov model of the natural history of cervical cancer was used ... Full text Link to item Cite

Venous thromboembolism during pregnancy and the postpartum period: incidence, risk factors, and mortality.

Journal article Am J Obstet Gynecol · May 2006 Featured Publication OBJECTIVE: The purpose of this study was to estimate the incidence, risk factors, and mortality from pregnancy-related venous thromboembolism. STUDY DESIGN: The Nationwide Inpatient Sample from the Healthcare Cost and Utilization Project of the Agency for ... Full text Link to item Cite

Acute myocardial infarction in pregnancy: a United States population-based study.

Journal article Circulation · March 28, 2006 Featured Publication BACKGROUND: The purpose of this study was to determine the incidence, mortality, and risk factors for pregnancy-related acute myocardial infarction in the United States. METHODS AND RESULTS: The Nationwide Inpatient Sample for the years 2000 to 2002 was qu ... Full text Link to item Cite

Cost-effectiveness of extending cervical cancer screening intervals among women with prior normal pap tests.

Journal article Obstet Gynecol · February 2006 Featured Publication OBJECTIVE: Annual cervical cancer screening in women with many prior normal Pap tests is common despite limited evidence on the cost-effectiveness of this strategy. We estimated the cost-effectiveness of screening women with 3 or more prior normal tests co ... Full text Link to item Cite

Cost-effectiveness analysis based on the atypical squamous cells of undetermined significance/low-grade squamous intraepithelial lesion Triage Study (ALTS).

Journal article J Natl Cancer Inst · January 18, 2006 Featured Publication BACKGROUND: The ALTS (atypical squamous cells of undetermined significance [ASCUS] and low-grade squamous intraepithelial lesion [LSIL] Triage Study) suggests that, for women diagnosed with ASCUS, human papillomavirus (HPV) DNA testing followed by referral ... Full text Link to item Cite

The FIBROID Registry: symptom and quality-of-life status 1 year after therapy.

Journal article Obstet Gynecol · December 2005 Featured Publication OBJECTIVES: To investigate the change in symptom severity and health-related quality of life among patients treated with uterine artery embolization for leiomyomata. METHODS: Using the Fibroid Registry for Outcomes Data (FIBROID), a multicenter, prospectiv ... Full text Link to item Cite

Incidence and risk factors for stroke in pregnancy and the puerperium.

Journal article Obstet Gynecol · September 2005 Featured Publication OBJECTIVE: To estimate the incidence, mortality, and risk factors for pregnancy-related stroke in the United States. METHODS: The Nationwide Inpatient Sample from the Healthcare Cost and Utilization Project of the Agency for Healthcare Research and Quality ... Full text Link to item Cite

Prospective data collection of a new procedure by a specialty society: the FIBROID registry.

Journal article Obstet Gynecol · July 2005 Featured Publication OBJECTIVE: To describe registry methods and baseline patient demographics from a national sample of women undergoing uterine artery embolization for uterine leiomyomata. METHODS: Interventional radiology practices were recruited to submit data by a secure ... Full text Link to item Cite

The Fibroid Registry for outcomes data (FIBROID) for uterine embolization: short-term outcomes.

Journal article Obstet Gynecol · July 2005 Featured Publication OBJECTIVE: To investigate the short-term safety of uterine embolization for leiomyomata in a large cohort of patients treated in a variety of clinical settings. METHODS: Examining the FIBROID Registry, a multicenter prospective voluntary registry of patien ... Full text Link to item Cite

Estimating live birth rates after ovulation induction in polycystic ovary syndrome: sample size calculations for the pregnancy in polycystic ovary syndrome trial.

Journal article Contemp Clin Trials · June 2005 Featured Publication Polycystic ovary syndrome (PCOS) affects approximately 5% of the female population, and is a leading cause of infertility, primarily secondary to anovulation. Clomiphene citrate has been standard therapy for ovulation induction in patients seeking pregnanc ... Full text Link to item Cite

FDG-PET for management of cervical and ovarian cancer.

Journal article Gynecol Oncol · April 2005 Featured Publication OBJECTIVE: To assess the diagnostic performance of Positron Emission Tomography using fluorodeoxyglucose (FDG-PET) in comparison to conventional imaging modalities in the assessment of patients with cervical and ovarian cancer. METHODS: Studies published b ... Full text Link to item Cite

Histological dating of timed endometrial biopsy tissue is not related to fertility status.

Journal article Fertil Steril · November 2004 Featured Publication OBJECTIVE: To assess the ability of histological dating to discriminate between women of fertile and infertile couples. The utility of histological dating of endometrium in the evaluation of infertile couples is uncertain. DESIGN: Prospective multicenter s ... Full text Link to item Cite

Testing for von Willebrand disease in women with menorrhagia: a systematic review.

Journal article Obstet Gynecol · August 2004 Featured Publication OBJECTIVE: To review the evidence supporting screening of adult women with menorrhagia for von Willebrand disease. DATA SOURCES: MEDLINE search from January 1,1990, to December 31, 2003, for articles in English, using keywords "menorrhagia," "von Willebran ... Full text Link to item Cite

Should older women have antepartum testing to prevent unexplained stillbirth?

Journal article Obstet Gynecol · July 2004 Featured Publication OBJECTIVE: Older women are at an increased risk for unexplained stillbirth late in pregnancy. The purpose of this study was to compare 3 strategies for the prevention of unexplained fetal death in women aged 35 years and older. We compared usual care (no a ... Full text Link to item Cite

Risk of cervical cancer associated with extending the interval between cervical-cancer screenings.

Journal article N Engl J Med · October 16, 2003 Featured Publication BACKGROUND: Although contemporary guidelines suggest that the intervals between Papanicolaou tests can be extended to three years among low-risk women with previous negative tests, the excess risk of cervical cancer associated with less frequent than annua ... Full text Link to item Cite

Potential health and economic impact of adding a human papillomavirus vaccine to screening programs.

Journal article JAMA · August 13, 2003 Featured Publication CONTEXT: Recently published results suggest that effective vaccines against cervical cancer-associated human papillomavirus (HPV) may become available within the next decade. OBJECTIVE: To examine the potential health and economic effects of an HPV vaccine ... Full text Link to item Cite

Effects of race and clinical factors on short-term outcomes of abdominal myomectomy.

Journal article Obstet Gynecol · May 2003 Featured Publication OBJECTIVE: To estimate the effects of race and preoperative uterine anatomy on complication rates after myomectomy. METHODS: A total of 239 abdominal myomectomies were performed at Duke University Medical Center from July 1992 through June 1998. Charts wer ... Full text Link to item Cite

Costs and effectiveness of alternative strategies for cervical cancer screening in military beneficiaries.

Journal article Obstet Gynecol · October 2002 Featured Publication OBJECTIVE: To estimate the potential effects, on costs and outcomes, of changes in sensitivity and specificity associated with new screening methods for cervical cancer in the military. METHODS: A Markov model of the natural history of cervical cancer was ... Full text Link to item Cite

Management of uterine leiomyomata: what do we really know?

Journal article Obstet Gynecol · July 2002 Featured Publication OBJECTIVE: To systematically review the literature on the surgical and nonsurgical management of uterine leiomyomata. DATA SOURCES: Published literature in English on the management of uterine leiomyomata published from 1975 through 2000 was identified in ... Full text Link to item Cite

Cost-effectiveness of universal cystoscopy to identify ureteral injury at hysterectomy.

Journal article Obstet Gynecol · May 2001 Featured Publication OBJECTIVE: To evaluate the cost-effectiveness of routine cystoscopy at the time of abdominal, vaginal, and laparoscopically assisted vaginal hysterectomy in terms of cost per ureteral injury identified and treated. METHODS: Using a hospital-based perspecti ... Full text Link to item Cite

Setting the target for a better cervical screening test: characteristics of a cost-effective test for cervical neoplasia screening.

Journal article Obstet Gynecol · November 2000 Featured Publication OBJECTIVE: To determine the potential effects on costs and outcomes of changes in sensitivity and specificity with new screening methods for cervical cancer. METHODS: Using a Markov model of the natural history of cervical cancer, we estimated the effects ... Full text Link to item Cite

Mathematical model for the natural history of human papillomavirus infection and cervical carcinogenesis.

Journal article Am J Epidemiol · June 15, 2000 Featured Publication The authors constructed a Markov model as part of a systematic review of cervical cytology conducted at the Duke University Evidence-based Practice Center (Durham, North Carolina) between October 1997 and September 1998. The model incorporated states for h ... Full text Link to item Cite

Risk adjustment for complications of hysterectomy: limitations of routinely collected administrative data.

Journal article Am J Obstet Gynecol · September 1999 Featured Publication OBJECTIVE: We sought to determine the utility of routinely collected administrative data for risk adjustment for complications of hysterectomy. STUDY DESIGN: Using abstracted discharge data on 107, 648 women undergoing hysterectomy in North Carolina from 1 ... Full text Link to item Cite

Cost-effectiveness of mandatory compared with voluntary screening for human immunodeficiency virus in pregnancy.

Journal article Obstet Gynecol · February 1998 Featured Publication OBJECTIVE: To determine the cost-effectiveness of mandatory screening for human immunodeficiency virus (HIV) in pregnancy compared with that of voluntary screening under varying assumptions about patient behavior. METHODS: Using a health care system perspe ... Full text Link to item Cite