Frederick Schachat

Journal article J Exp Biol · October 2002 Featured Publication Extraocular muscles (EOMs) are the most molecularly heterogeneous and physiologically diverse mammalian striated muscles. They express the entire array of striated muscle myosins, including a specialized myosin heavy chain MYH13, which is restricted to ext ... Full text Link to item Cite

Phylogenetic implications of the superfast myosin in extraocular muscles.

Journal article J Exp Biol · August 2002 Featured Publication Extraocular muscle exhibits higher-velocity and lower-tension contractions than other vertebrate striated muscles. These distinctive physiological properties are associated with the expression of a novel extraocular myosin heavy chain (MYH). Encoded by the ... Full text Link to item Cite

Longitudinal variation in muscle protein expression and contraction kinetics of largemouth bass axial muscle.

Journal article J Exp Biol · December 2001 Featured Publication The present study investigates muscle protein expression in largemouth bass Micropterus salmoides through intra- and intermyomeric comparisons of white muscle. Using denaturing SDS-polyacrylamide gel electrophoresis, muscle protein expression in the arm an ... Full text Link to item Cite

Fluorescence changes on contractile activation in TnC(DANZ) labeled skinned rabbit psoas fibers.

Journal article J Muscle Res Cell Motil · 2001 Featured Publication The increase in fluorescence of dansylaziridine (DANZ) labeled troponin C (TnC(DANZ) substituted into skinned rabbit psoas fibers was determined as a function of the pCa. The fluorescence data are expressed as the ratio of two wavelength bands, one that se ... Full text Link to item Cite

Differences in skeletal muscle between men and women with chronic heart failure.

Journal article J Appl Physiol (1985) · January 2001 Featured Publication Men with chronic heart failure (CHF) have alterations in their skeletal muscle that are partially responsible for a decreased exercise tolerance. The purpose of this study was to investigate whether skeletal muscle alterations in women with CHF are similar ... Full text Link to item Cite

Early specialization of the superfast myosin in extraocular and laryngeal muscles.

Journal article J Exp Biol · August 2000 Featured Publication Extraocular muscle (EOM) exhibits high-velocity, low-tension contractions compared with other vertebrate striated muscles. These distinctive properties have been associated with a novel myosin heavy chain (MyHC) isoform, MyHC-EO. An atypical MyHC, MyHC IIL ... Full text Link to item Cite

Isoforms of alpha-actinin from cardiac, smooth, and skeletal muscle form polar arrays of actin filaments.

Journal article J Cell Biol · May 1, 2000 Featured Publication We have used a positively charged lipid monolayer to form two-dimensional bundles of F-actin cross-linked by alpha-actinin to investigate the relative orientation of the actin filaments within them. This method prevents growth of the bundles perpendicular ... Full text Link to item Cite