Scholars@Duke

• Background
• 

  Education, Training, & Certifications

  • Postdoctoral Fellow, Stanford University 1998 - 2003
  • Ph.D., Columbia University 1998
• 

  Duke Appointment History

  • Professor in Cell Biology, Cell Biology, Basic Science Departments 2017 - 2018
  • Associate Professor in Cell Biology, Cell Biology, Basic Science Departments 2013 - 2017
  • Associate Professor of Neurobiology, Neurobiology, Basic Science Departments 2013 - 2017
  • Assistant Professor in Neurobiology, Neurobiology, Basic Science Departments 2004 - 2013
  • Associate Professor of Cell Biology, Cell Biology, Basic Science Departments 2010 - 2013
  • Assistant Professor of Cell Biology, Cell Biology, Basic Science Departments 2003 - 2010
• Recognition
• 

  In the News

  • APR 18, 2019

    General Anesthesia Hijacks Sleep Circuitry to Knock You Out

  • AUG 9, 2016

    Duke Brain Researchers Receive Award From Keck Foundation

  • MAR 30, 2016

    Fan Wang wins Brain Research Foundation award

  • JAN 6, 2015

    Researchers Map Direct Gut-Brain Connection

  • NOV 24, 2014

    Five Faculty Named Fellows of American Association for the Advancement of Science

  • JUN 3, 2014

    Complex Neural Circuitry Keeps You From Biting Your Tongue

  • OCT 16, 2013

    Glowing Neurons Reveal Networked Link Between Brain, Whiskers
• 

  Awards & Honors

  • AAAS Fellow. American Association for the Advancement of Science. 2014
  • Sloan Research Fellowship-Neuroscience. Alfred P. Sloan Foundation. 2004
• Research
• 

  Selected Grants

  • Molecular and circuitry mechanism underlying autism behaviors in Shank3 mouse models awarded by National Institutes of Health 2019 - 2023
  • Cortical Signature and Modulation of Pain awarded by National Institutes of Health 2018 - 2023
  • Pre-motor Neural Circuits for Exploratory Movement awarded by National Institutes of Health 2013 - 2023
  • Using Genetic Tools to Dissect Neural Circuits for Social Communication awarded by National Institutes of Health 2018 - 2023
  • Identifying neurons and circuits mediating anesthesia-induced unconsciousness awarded by International Human Frontier Science Program Organization 2018 - 2021
  • A fully biological platform for monitoring mesoscale neural activity awarded by National Institutes of Health 2018 - 2020
  • Separate channels of tactile information in the somatosensory system awarded by US-Israel Binational Science Foundation 2016 - 2020
  • A novel paradigm to dissect the function connectivity in Shank3 autism model awarded by National Institutes of Health 2017 - 2019
  • Gut-Brain Neurocircuit Modulating Eating Behavior awarded by National Institutes of Health 2015 - 2019
  • Taking DISCO Live: Dual pathway Imaging of Striatal Circuit Output in vivo awarded by National Institutes of Health 2017 - 2019
  • A method for anterograde trans-synaptic tracing awarded by University of Southern California 2018 - 2019
  • Unraveling the neural gate to consciousness awarded by W.M. Keck Foundation 2016 - 2019
  • Reverse engineering the brain stem circuits that govern exploratory behavior awarded by University of California - San Diego 2018 - 2019
  • Toward causal neuroscience: capture and manipulate emergent neuronal ensembles awarded by National Institutes of Health 2013 - 2019
  • Functions of distinct trigeminal brainstem projection pathways in tactile behavior awarded by National Institutes of Health 2017 - 2019
  • Unravel the Neuronal Pathways Underlying Anesthesia-Induced Loss of Consciousness awarded by Brain Research Foundation 2016 - 2018
  • Understanding Sleep Disturbance in Alzheimer's Disease awarded by Ruth K. Broad Biomedical Research Foundation 2017 - 2018
  • Generating Multiple Circuit and Neuron Type Specific AAV Vectors With Cross-Species Applicability awarded by Boston Children's Hospital 2015 - 2018
  • Functional Characterization of Parabrachial Circuits Processing Noxious Thermal Pain awarded by National Institutes of Health 2015 - 2018
  • Determining Functions of a Brainstem Pre-motor Module In Masticatory Jaw Movement awarded by National Institutes of Health 2013 - 2016
  • Control of trigeminal touch sensory circuit assembly awarded by National Institutes of Health 2009 - 2016
  • Genetically encoded anatomical probes for neuronal activity and plasticity awarded by National Institutes of Health 2009 - 2014
  • Trigeminal mechanisms underlie distinct orofacial pain awarded by National Institutes of Health 2005 - 2011
  • The Role of transcription factor Sox2 in the homeostasis of the adult esophagus awarded by National Institutes of Health 2010
• Publications & Artistic Works
• 

  Selected Publications

  • Academic Articles

    • Jiang-Xie, L-F, Yin, L, Zhao, S, Prevosto, V, Han, B-X, Dzirasa, K, and Wang, F. "A Common Neuroendocrine Substrate for Diverse General Anesthetics and Sleep." Neuron (April 5, 2019).  Full Text
    • Tschida, K, Michael, V, Takato, J, Han, B-X, Zhao, S, Sakurai, K, Mooney, R, and Wang, F. "A Specialized Neural Circuit Gates Social Vocalizations in the Mouse." (September 14, 2018).
    • Lu, J, Li, C, Singh-Alvarado, J, Zhou, ZC, Fröhlich, F, Mooney, R, and Wang, F. "MIN1PIPE: A Miniscope 1-Photon-Based Calcium Imaging Signal Extraction Pipeline." Cell Reports 23, no. 12 (June 2018): 3673-3684.  Full Text
    • Rodriguez, E, Sakurai, K, Xu, J, Chen, Y, Toda, K, Zhao, S, Han, B-X, Ryu, D, Yin, H, Liedtke, W, and Wang, F. "Publisher Correction: A craniofacial-specific monosynaptic circuit enables heightened affective pain." Nature Neuroscience 21, no. 6 (June 2018): 896-null.  Full Text
    • McElvain, LE, Friedman, B, Karten, HJ, Svoboda, K, Wang, F, Deschênes, M, and Kleinfeld, D. "Circuits in the rodent brainstem that control whisking in concert with other orofacial motor actions." Neuroscience 368 (January 2018): 152-170. (Review)  Full Text
    • Takatoh, J, Prevosto, V, and Wang, F. "Vibrissa sensory neurons: Linking distinct morphology to specific physiology and function." Neuroscience 368 (January 2018): 109-114. (Review)  Full Text
    • Rodriguez, E, Sakurai, K, Xu, J, Chen, Y, Toda, K, Zhao, S, Han, B-X, Ryu, D, Yin, H, Liedtke, W, and Wang, F. "A craniofacial-specific monosynaptic circuit enables heightened affective pain." Nature Neuroscience 20, no. 12 (December 2017): 1734-1743.  Full Text  Open Access Copy
    • Strege, PR, Knutson, K, Eggers, SJ, Li, JH, Wang, F, Linden, D, Szurszewski, JH, Milescu, L, Leiter, AB, Farrugia, G, and Beyder, A. "Sodium channel Na V 1.3 is important for enterochromaffin cell excitability and serotonin release." Scientific Reports 7, no. 1 (December 1, 2017).  Full Text
    • Bellavance, MA, Takatoh, J, Lu, J, Demers, M, Kleinfeld, D, Wang, F, and Deschênes, M. "Correction: Parallel Inhibitory and Excitatory Trigemino-Facial Feedback Circuitry for Reflexive Vibrissa Movement (Neuron (2017) 95(3) (673–682.e4) (S0896627317305974)(10.1016/j.neuron.2017.06.045))." Neuron 95, no. 3 (August 2, 2017): 722-723.  Full Text
    • Bellavance, M-A, Takatoh, J, Lu, J, Demers, M, Kleinfeld, D, Wang, F, and Deschênes, M. "Parallel Inhibitory and Excitatory Trigemino-Facial Feedback Circuitry for Reflexive Vibrissa Movement." Neuron 95, no. 3 (August 2017): 673-682.e4.  Full Text
    • Wang, F, Knutson, K, Alcaino, C, Linden, DR, Gibbons, SJ, Kashyap, P, Grover, M, Oeckler, R, Gottlieb, PA, Li, HJ, Leiter, AB, Farrugia, G, and Beyder, A. "Mechanosensitive ion channel Piezo2 is important for enterochromaffin cell response to mechanical forces." The Journal of Physiology 595, no. 1 (January 2017): 79-91.  Full Text
    • Sakurai, K, Zhao, S, Takatoh, J, Rodriguez, E, Lu, J, Leavitt, AD, Fu, M, Han, B-X, and Wang, F. "Capturing and Manipulating Activated Neuronal Ensembles with CANE Delineates a Hypothalamic Social-Fear Circuit." Neuron 92, no. 4 (November 2016): 739-753.  Full Text  Open Access Copy
    • Stanek, E, Rodriguez, E, Zhao, S, Han, B-X, and Wang, F. "Supratrigeminal Bilaterally Projecting Neurons Maintain Basal Tone and Enable Bilateral Phasic Activation of Jaw-Closing Muscles." The Journal of Neuroscience : the Official Journal of the Society for Neuroscience 36, no. 29 (July 2016): 7663-7675.  Full Text
    • Wang, X, Bey, AL, Katz, BM, Badea, A, Kim, N, David, LK, Duffney, LJ, Kumar, S, Mague, SD, Hulbert, SW, Dutta, N, Hayrapetyan, V, Yu, C, Gaidis, E, Zhao, S, Ding, J-D, Xu, Q, Chung, L, Rodriguiz, RM, Wang, F, Weinberg, RJ, Wetsel, WC, Dzirasa, K, Yin, H, and Jiang, Y-H. "Altered mGluR5-Homer scaffolds and corticostriatal connectivity in a Shank3 complete knockout model of autism." Nature Communications 7 (May 10, 2016): 11459-null.  Full Text  Open Access Copy
    • Deschênes, M, Takatoh, J, Kurnikova, A, Moore, JD, Demers, M, Elbaz, M, Furuta, T, Wang, F, and Kleinfeld, D. "Inhibition, Not Excitation, Drives Rhythmic Whisking." Neuron 90, no. 2 (April 2016): 374-387.  Full Text  Open Access Copy
    • Xu, Z-Z, Kim, YH, Bang, S, Zhang, Y, Berta, T, Wang, F, Oh, SB, and Ji, R-R. "Inhibition of mechanical allodynia in neuropathic pain by TLR5-mediated A-fiber blockade." Nature Medicine 21, no. 11 (November 2015): 1326-1331.  Full Text
    • Zhang, Y, Zhao, S, Rodriguez, E, Takatoh, J, Han, B-X, Zhou, X, and Wang, F. "Identifying local and descending inputs for primary sensory neurons." The Journal of Clinical Investigation 125, no. 10 (October 2015): 3782-3794.  Full Text
    • Kim, IH, Rossi, MA, Aryal, DK, Racz, B, Kim, N, Uezu, A, Wang, F, Wetsel, WC, Weinberg, RJ, Yin, H, and Soderling, SH. "Spine pruning drives antipsychotic-sensitive locomotion via circuit control of striatal dopamine." Nature Neuroscience 18, no. 6 (June 2015): 883-891.  Full Text
    • Zhang, Y, Chen, Y, Liedtke, W, and Wang, F. "Lack of evidence for ectopic sprouting of genetically labeled Aβ touch afferents in inflammatory and neuropathic trigeminal pain." Molecular Pain 11 (April 10, 2015): 18-null.  Full Text  Open Access Copy
    • Matthews, DW, Deschênes, M, Furuta, T, Moore, JD, Wang, F, Karten, HJ, and Kleinfeld, D. "Feedback in the brainstem: an excitatory disynaptic pathway for control of whisking." The Journal of comparative neurology 523, no. 6 (April 2015): 921-942.  Full Text
    • Bohorquez, DV, Shahid, RA, Erdmann, A, Kreger, AM, Wang, Y, Calakos, N, Wang, F, and Liddle, RA. "Neuroepithelial circuit formed by innervation of sensory enteroendocrine cells." JOURNAL OF CLINICAL INVESTIGATION 125, no. 2 (February 2015): 782-786.  Full Text  Link to Item
    • Bohórquez, DV, Shahid, RA, Erdmann, A, Kreger, AM, Wang, Y, Calakos, N, Wang, F, and Liddle, RA. "Neuroepithelial circuit formed by innervation of sensory enteroendocrine cells." J Clin Invest 125, no. 2 (February 2015): 782-786.  Full Text  Open Access Copy  Link to Item
    • Bráz, JM, Wang, F, and Basbaum, AI. "Presynaptic Inputs to Any CNS Projection Neuron Identified by Dual Recombinant Virus Infection." PloS one 10, no. 10 (January 2015): e0140681-.  Full Text  Open Access Copy
    • Chen, Y, Kanju, P, Fang, Q, Lee, SH, Parekh, PK, Lee, W, Moore, C, Brenner, D, Gereau, RW, Wang, F, and Liedtke, W. "TRPV4 is necessary for trigeminal irritant pain and functions as a cellular formalin receptor." Pain 155, no. 12 (December 2014): 2662-2672.  Full Text  Open Access Copy
    • Neufeld, SJ, Wang, F, and Cobb, J. "Genetic interactions between Shox2 and Hox genes during the regional growth and development of the mouse limb." Genetics 198, no. 3 (November 2014): 1117-1126.  Full Text
    • Halassa, MM, Chen, Z, Wimmer, RD, Brunetti, PM, Zhao, S, Zikopoulos, B, Wang, F, Brown, EN, and Wilson, MA. "State-dependent architecture of thalamic reticular subnetworks." Cell 158, no. 4 (August 2014): 808-821.  Full Text
    • Moore, JD, Kleinfeld, D, and Wang, F. "How the brainstem controls orofacial behaviors comprised of rhythmic actions." Trends in Neurosciences 37, no. 7 (July 2014): 370-380. (Review)  Full Text
    • Kleinfeld, D, Deschênes, M, Wang, F, and Moore, JD. "More than a rhythm of life: breathing as a binder of orofacial sensation." Nature neuroscience 17, no. 5 (May 2014): 647-651. (Review)  Full Text
    • Stanek, E, Cheng, S, Takatoh, J, Han, B-X, and Wang, F. "Monosynaptic premotor circuit tracing reveals neural substrates for oro-motor coordination." Elife 3 (April 30, 2014): e02511-null.  Full Text
    • Kleinfeld, D, Moore, JD, Wang, F, and Deschênes, M. "The Brainstem Oscillator for Whisking and the Case for Breathing as the Master Clock for Orofacial Motor Actions." Cold Spring Harbor Symposia on Quantitative Biology 79 (January 2014): 29-39.  Full Text
    • Moore, JD, Kleinfeld, D, and Wang, F. "How the brainstem controls orofacial behaviors comprised of rhythmic actions." Trends in Neurosciences 37, no. 7 (January 1, 2014): 370-380. (Review)  Full Text
    • Sakurai, K, Akiyama, M, Cai, B, Scott, A, Han, B-X, Takatoh, J, Sigrist, M, Arber, S, and Wang, F. "The organization of submodality-specific touch afferent inputs in the vibrissa column." Cell Rep 5, no. 1 (October 17, 2013): 87-98.  Full Text  Link to Item
    • Nelson, A, Schneider, DM, Takatoh, J, Sakurai, K, Wang, F, and Mooney, R. "A circuit for motor cortical modulation of auditory cortical activity." The Journal of Neuroscience : the Official Journal of the Society for Neuroscience 33, no. 36 (September 2013): 14342-14353.  Full Text
    • Wang, F, and He, Z. "Axon Maintenance and Degeneration." (August 29, 2013): 177-189. (Chapter)  Full Text
    • Chen, Y, Williams, SH, McNulty, AL, Hong, JH, Lee, SH, Rothfusz, NE, Parekh, PK, Moore, C, Gereau, RW, Taylor, AB, Wang, F, Guilak, F, and Liedtke, W. "Temporomandibular joint pain: a critical role for Trpv4 in the trigeminal ganglion." Pain 154, no. 8 (August 2013): 1295-1304.  Full Text  Open Access Copy
    • Pagadala, P, Park, C-K, Bang, S, Xu, Z-Z, Xie, R-G, Liu, T, Han, B-X, Tracey, WD, Wang, F, and Ji, R-R. "Loss of NR1 subunit of NMDARs in primary sensory neurons leads to hyperexcitability and pain hypersensitivity: involvement of Ca(2+)-activated small conductance potassium channels." The Journal of Neuroscience : the Official Journal of the Society for Neuroscience 33, no. 33 (August 2013): 13425-13430.  Full Text
    • Chen, Y, Williams, SH, McNulty, AL, Hong, JH, Lee, SH, Rothfusz, NE, Parekh, PK, Moore, C, IV, RWG, Taylor, AB, Wang, F, Guilak, F, and Liedtke, W. "Temporomandibular joint pain: A critical role for Trpv4 in the trigeminal ganglion." Pain 154, no. 8 (2013): 1295-1304.  Full Text
    • Devereaux, K, Dall'Armi, C, Alcazar-Roman, A, Ogasawara, Y, Zhou, X, Wang, F, Yamamoto, A, De Camilli, P, and Di Paolo, G. "Regulation of mammalian autophagy by class II and III PI 3-kinases through PI3P synthesis." Plos One 8, no. 10 (January 2013): e76405-null.  Full Text
    • Sakurai, K, Akiyama, M, Cai, B, Scott, A, Han, B-X, Takatoh, J, Sigrist, M, Arber, S, and Wang, F. "The Organization of Submodality-Specific Touch Afferent Inputs in the Vibrissa Column." Cell Reports 5, no. 1 (2013): 87-98.  Full Text
    • Takatoh, J, Nelson, A, Zhou, X, Bolton, MM, Ehlers, MD, Arenkiel, BR, Mooney, R, and Wang, F. "New modules are added to vibrissal premotor circuitry with the emergence of exploratory whisking." Neuron 77, no. 2 (January 2013): 346-360.  Full Text
    • Liu, Y, Rutlin, M, Huang, S, Barrick, CA, Wang, F, Jones, KR, Tessarollo, L, and Ginty, DD. "Sexually Dimorphic BDNF Signaling Directs Sensory Innervation of the Mammary Gland." SCIENCE 338, no. 6112 (December 7, 2012): 1357-1360.  Full Text  Link to Item
    • Chen, TR, Wang, P, Carroll, LK, Zhang, Y-J, Han, B-X, and Wang, F. "Generation and characterization of Tmeff2 mutant mice." Biochem Biophys Res Commun 425, no. 2 (August 24, 2012): 189-194.  Full Text  Link to Item
    • Cho, H, Yang, YD, Lee, J, Lee, B, Kim, T, Jang, Y, Back, SK, Na, HS, Harfe, BD, Wang, F, Raouf, R, Wood, JN, and Oh, U. "The calcium-activated chloride channel anoctamin 1 acts as a heat sensor in nociceptive neurons." Nature Neuroscience 15, no. 7 (May 27, 2012): 1015-1021.  Full Text
    • Takatoh, J, and Wang, F. "Axonally translated SMADs link up BDNF and retrograde BMP signaling." Neuron 74, no. 1 (April 12, 2012): 3-5.  Full Text  Link to Item
    • Klionsky, DJ, Abdalla, FC, Abeliovich, H, Abraham, RT, Acevedo-Arozena, A, Adeli, K, Agholme, L, Agnello, M, Agostinis, P, Aguirre-Ghiso, JA, Ahn, HJ, Ait-Mohamed, O, Ait-Si-Ali, S, Akematsu, T, Akira, S, Al-Younes, HM, Al-Zeer, MA, Albert, ML, Albin, RL, Alegre-Abarrategui, J, Aleo, MF, Alirezaei, M, Almasan, A, Almonte-Becerril, M, Amano, A, Amaravadi, R, Amarnath, S, Amer, AO, Andrieu-Abadie, N, Anantharam, V, Ann, DK, Anoopkumar-Dukie, S, Aoki, H, Apostolova, N, Arancia, G, Aris, JP, Asanuma, K, Asare, NYO, Ashida, H, Askanas, V, Askew, DS, Auberger, P, Baba, M, Backues, SK, Baehrecke, EH, Bahr, BA, Bai, X-Y, Bailly, Y, Baiocchi, R, Baldini, G, Balduini, W, Ballabio, A, Bamber, BA, Bampton, ETW, Bánhegyi, G, Bartholomew, CR, Bassham, DC, Bast, RC, Batoko, H, Bay, B-H, Beau, I, Béchet, DM, Begley, TJ, Behl, C, Behrends, C, Bekri, S, Bellaire, B, Bendall, LJ, Benetti, L, Berliocchi, L, Bernardi, H, Bernassola, F, Besteiro, S, Bhatia-Kissova, I, Bi, X, Biard-Piechaczyk, M, Blum, JS, Boise, LH, Bonaldo, P, Boone, DL, Bornhauser, BC, Bortoluci, KR, Bossis, I, Bost, F, Bourquin, J-P, Boya, P, Boyer-Guittaut, M, Bozhkov, PV, Brady, NR, Brancolini, C, Brech, A, Brenman, JE, Brennand, A, Bresnick, EH, Brest, P, Bridges, D, Bristol, ML, Brookes, PS, Brown, EJ, Brumell, JH, Brunetti-Pierri, N, Brunk, UT, Bulman, DE, Bultman, SJ, Bultynck, G, Burbulla, LF, Bursch, W, Butchar, JP, Buzgariu, W, Bydlowski, SP, Cadwell, K, Cahová, M, Cai, D, Cai, J, Cai, Q, Calabretta, B, Calvo-Garrido, J, Camougrand, N, Campanella, M, Campos-Salinas, J, Candi, E, Cao, L, Caplan, AB, Carding, SR, Cardoso, SM, Carew, JS, Carlin, CR, Carmignac, V, Carneiro, LAM, Carra, S, Caruso, RA, Casari, G, Casas, C, Castino, R, Cebollero, E, Cecconi, F, Celli, J, Chaachouay, H, Chae, H-J, Chai, C-Y, Chan, DC, Chan, EY, Chang, RC-C, Che, C-M, Chen, C-C, Chen, G-C, Chen, G-Q, Chen, M, Chen, Q, Chen, SS-L, Chen, W, Chen, X, Chen, X, Chen, X, Chen, Y-G, Chen, Y, Chen, Y, Chen, Y-J, Chen, Z, Cheng, A, Cheng, CHK, Cheng, Y, Cheong, H, Cheong, J-H, Cherry, S, Chess-Williams, R, Cheung, ZH, Chevet, E, Chiang, H-L, Chiarelli, R, Chiba, T, Chin, L-S, Chiou, S-H, Chisari, FV, Cho, CH, Cho, D-H, Choi, AMK, Choi, D, Choi, KS, Choi, ME, Chouaib, S, Choubey, D, Choubey, V, Chu, CT, Chuang, T-H, Chueh, S-H, Chun, T, Chwae, Y-J, Chye, M-L, Ciarcia, R, Ciriolo, MR, Clague, MJ, Clark, RSB, Clarke, PGH, Clarke, R, Codogno, P, Coller, HA, Colombo, MI, Comincini, S, Condello, M, Condorelli, F, Cookson, MR, Coombs, GH, Coppens, I, Corbalan, R, Cossart, P, Costelli, P, Costes, S, Coto-Montes, A, Couve, E, Coxon, FP, Cregg, JM, Crespo, JL, Cronjé, MJ, Cuervo, AM, Cullen, JJ, Czaja, MJ, D'Amelio, M, Darfeuille-Michaud, A, Davids, LM, Davies, FE, De Felici, M, de Groot, JF, de Haan, CAM, De Martino, L, De Milito, A, De Tata, V, Debnath, J, Degterev, A, Dehay, B, Delbridge, LMD, Demarchi, F, Deng, YZ, Dengjel, J, Dent, P, Denton, D, Deretic, V, Desai, SD, Devenish, RJ, Di Gioacchino, M, Di Paolo, G, Di Pietro, C, Díaz-Araya, G, Díaz-Laviada, I, Diaz-Meco, MT, Diaz-Nido, J, Dikic, I, Dinesh-Kumar, SP, Ding, W-X, Distelhorst, CW, Diwan, A, Djavaheri-Mergny, M, Dokudovskaya, S, Dong, Z, Dorsey, FC, Dosenko, V, Dowling, JJ, Doxsey, S, Dreux, M, Drew, ME, Duan, Q, Duchosal, MA, Duff, K, Dugail, I, Durbeej, M, Duszenko, M, Edelstein, CL, Edinger, AL, Egea, G, Eichinger, L, Eissa, NT, Ekmekcioglu, S, El-Deiry, WS, Elazar, Z, Elgendy, M, Ellerby, LM, Eng, KE, Engelbrecht, A-M, Engelender, S, Erenpreisa, J, Escalante, R, Esclatine, A, Eskelinen, E-L, Espert, L, Espina, V, Fan, H, Fan, J, Fan, Q-W, Fan, Z, Fang, S, Fang, Y, Fanto, M, Fanzani, A, Farkas, T, Farré, J-C, Faure, M, Fechheimer, M, Feng, CG, Feng, J, Feng, Q, Feng, Y, Fésüs, L, Feuer, R, Figueiredo-Pereira, ME, Fimia, GM, Fingar, DC, Finkbeiner, S, Finkel, T, Finley, KD, Fiorito, F, Fisher, EA, Fisher, PB, Flajolet, M, Florez-McClure, ML, Florio, S, Fon, EA, Fornai, F, Fortunato, F, Fotedar, R, Fowler, DH, Fox, HS, Franco, R, Frankel, LB, Fransen, M, Fuentes, JM, Fueyo, J, Fujii, J, Fujisaki, K, Fujita, E, Fukuda, M, Furukawa, RH, Gaestel, M, Gailly, P, Gajewska, M, Galliot, B, Galy, V, Ganesh, S, Ganetzky, B, Ganley, IG, Gao, F-B, Gao, GF, Gao, J, Garcia, L, Garcia-Manero, G, Garcia-Marcos, M, Garmyn, M, Gartel, AL, Gatti, E, Gautel, M, Gawriluk, TR, Gegg, ME, Geng, J, Germain, M, Gestwicki, JE, Gewirtz, DA, Ghavami, S, Ghosh, P, Giammarioli, AM, Giatromanolaki, AN, Gibson, SB, Gilkerson, RW, Ginger, ML, Ginsberg, HN, Golab, J, Goligorsky, MS, Golstein, P, Gomez-Manzano, C, Goncu, E, Gongora, C, Gonzalez, CD, Gonzalez, R, González-Estévez, C, González-Polo, RA, Gonzalez-Rey, E, Gorbunov, NV, Gorski, S, Goruppi, S, Gottlieb, RA, Gozuacik, D, Granato, GE, Grant, GD, Green, KN, Gregorc, A, Gros, F, Grose, C, Grunt, TW, Gual, P, Guan, J-L, Guan, K-L, Guichard, SM, Gukovskaya, AS, Gukovsky, I, Gunst, J, Gustafsson, AB, Halayko, AJ, Hale, AN, Halonen, SK, Hamasaki, M, Han, F, Han, T, Hancock, MK, Hansen, M, Harada, H, Harada, M, Hardt, SE, Harper, JW, Harris, AL, Harris, J, Harris, SD, Hashimoto, M, Haspel, JA, Hayashi, S-I, Hazelhurst, LA, He, C, He, Y-W, Hébert, M-J, Heidenreich, KA, Helfrich, MH, Helgason, GV, Henske, EP, Herman, B, Herman, PK, Hetz, C, Hilfiker, S, Hill, JA, Hocking, LJ, Hofman, P, Hofmann, TG, Höhfeld, J, Holyoake, TL, Hong, M-H, Hood, DA, Hotamisligil, GS, Houwerzijl, EJ, Høyer-Hansen, M, Hu, B, Hu, C-AA, Hu, H-M, Hua, Y, Huang, C, Huang, J, Huang, S, Huang, W-P, Huber, TB, Huh, W-K, Hung, T-H, Hupp, TR, Hur, GM, Hurley, JB, Hussain, SNA, Hussey, PJ, Hwang, JJ, Hwang, S, Ichihara, A, Ilkhanizadeh, S, Inoki, K, Into, T, Iovane, V, Iovanna, JL, Ip, NY, Isaka, Y, Ishida, H, Isidoro, C, Isobe, K-I, Iwasaki, A, Izquierdo, M, Izumi, Y, Jaakkola, PM, Jäättelä, M, Jackson, GR, Jackson, WT, Janji, B, Jendrach, M, Jeon, J-H, Jeung, E-B, Jiang, H, Jiang, H, Jiang, JX, Jiang, M, Jiang, Q, Jiang, X, Jiménez, A, Jin, M, Jin, S, Joe, CO, Johansen, T, Johnson, DE, Johnson, GVW, Jones, NL, Joseph, B, Joseph, SK, Joubert, AM, Juhász, G, Juillerat-Jeanneret, L, Jung, CH, Jung, Y-K, Kaarniranta, K, Kaasik, A, Kabuta, T, and Kadowaki, M et al.. "Guidelines for the use and interpretation of assays for monitoring autophagy." Autophagy 8, no. 4 (April 2012): 445-544.  Full Text
    • Raouf, R, Rugiero, F, Kiesewetter, H, Hatch, R, Hummler, E, Nassar, MA, Wang, F, and Wood, JN. "Sodium channels and mammalian sensory mechanotransduction." Molecular Pain 8 (March 26, 2012): 21-null.  Full Text
    • Minett, MS, Nassar, MA, Clark, AK, Passmore, G, Dickenson, AH, Wang, F, Malcangio, M, and Wood, JN. "Distinct Nav1.7-dependent pain sensations require different sets of sensory and sympathetic neurons." Nature Communications 3 (2012).  Full Text
    • Raouf, R, Rugiero, F, Kiesewetter, H, Hatch, R, Hummler, E, Nassar, MA, Wang, F, and Wood, JN. "Sodium channels and mammalian sensory mechanotransduction." Molecular Pain 8 (2012).  Full Text
    • Wang, P, Chen, T, Sakurai, K, Han, B-X, He, Z, Feng, G, and Wang, F. "Intersectional Cre driver lines generated using split-intein mediated split-Cre reconstitution." Sci Rep 2 (2012): 497-.  Full Text  Link to Item
    • Lau, J, Minett, MS, Zhao, J, Dennehy, U, Wang, F, Wood, JN, and Bogdanov, YD. "Temporal control of gene deletion in sensory ganglia using a tamoxifen-inducible Advillin-Cre-ERT2 recombinase mouse." Molecular Pain 7 (December 21, 2011): 100-null.  Full Text
    • McLeod, IX, Zhou, X, Li, Q-J, Wang, F, and He, Y-W. "The class III kinase Vps34 promotes T lymphocyte survival through regulating IL-7Rα surface expression." Journal of Immunology (Baltimore, Md. : 1950) 187, no. 10 (November 2011): 5051-5061.  Full Text
    • Leslie, JR, Imai, F, Fukuhara, K, Takegahara, N, Rizvi, TA, Friedel, RH, Wang, F, Kumanogoh, A, and Yoshida, Y. "Ectopic myelinating oligodendrocytes in the dorsal spinal cord as a consequence of altered semaphorin 6D signaling inhibit synapse formation." Development (Cambridge, England) 138, no. 18 (September 2011): 4085-4095.  Full Text
    • Scott, A, Hasegawa, H, Sakurai, K, Yaron, A, Cobb, J, and Wang, F. "Transcription factor short stature homeobox 2 is required for proper development of tropomyosin-related kinase B-expressing mechanosensory neurons." The Journal of Neuroscience : the Official Journal of the Society for Neuroscience 31, no. 18 (May 2011): 6741-6749.  Full Text
    • da Silva, S, Hasegawa, H, Scott, A, Zhou, X, Wagner, AK, Han, B-X, and Wang, F. "Proper formation of whisker barrelettes requires periphery-derived Smad4-dependent TGF-beta signaling." Proc Natl Acad Sci U S A 108, no. 8 (February 22, 2011): 3395-3400.  Full Text  Link to Item
    • da Silva, S, and Wang, F. "Retrograde neural circuit specification by target-derived neurotrophins and growth factors." Curr Opin Neurobiol 21, no. 1 (February 2011): 61-67. (Review)  Full Text  Link to Item
    • Zhou, X, Takatoh, J, and Wang, F. "The mammalian class 3 PI3K (PIK3C3) is required for early embryogenesis and cell proliferation." Plos One 6, no. 1 (January 20, 2011): e16358-null.  Full Text
    • Wang, L, Budolfson, K, and Wang, F. "Pik3c3 deletion in pyramidal neurons results in loss of synapses, extensive gliosis and progressive neurodegeneration." Neuroscience 172 (January 13, 2011): 427-442.  Full Text  Link to Item
    • Arenkiel, BR, Hasegawa, H, Yi, JJ, Larsen, RS, Wallace, ML, Philpot, BD, Wang, F, and Ehlers, MD. "Activity-induced remodeling of olfactory bulb microcircuits revealed by monosynaptic tracing." PLoS ONE 6, no. 12 (2011).  Full Text
    • Rodriguez, P, Da Silva, S, Oxburgh, L, Wang, F, Hogan, BLM, and Que, J. "BMP signaling in the development of the mouse esophagus and forestomach." Development (Cambridge, England) 137, no. 24 (December 2010): 4171-4176.  Full Text  Open Access Copy
    • Abe, N, Borson, SH, Gambello, MJ, Wang, F, and Cavalli, V. "Mammalian target of rapamycin (mTOR) activation increases axonal growth capacity of injured peripheral nerves." The Journal of Biological Chemistry 285, no. 36 (September 2010): 28034-28043.  Full Text
    • Zhou, X, and Wang, F. "Effects of neuronal PIK3C3/Vps34 deletion on autophagy and beyond." Autophagy 6, no. 6 (August 2010): 798-799.  Open Access Copy  Link to Item
    • Zhou, X, Wang, L, Hasegawa, H, Amin, P, Han, B-X, Kaneko, S, He, Y, and Wang, F. "Deletion of PIK3C3/Vps34 in sensory neurons causes rapid neurodegeneration by disrupting the endosomal but not the autophagic pathway." Proceedings of the National Academy of Sciences of the United States of America 107, no. 20 (May 3, 2010): 9424-9429.  Full Text
    • Rawlins, EL, Okubo, T, Xue, Y, Brass, DM, Auten, RL, Hasegawa, H, Wang, F, and Hogan, BLM. "The role of Scgb1a1+ Clara cells in the long-term maintenance and repair of lung airway, but not alveolar, epithelium." Cell Stem Cell 4, no. 6 (June 2009): 525-534.  Full Text
    • Kessler, JD, Hasegawa, H, Brun, SN, Emmenegger, BA, Yang, Z-J, Dutton, JW, Wang, F, and Wechsler-Reya, RJ. "N-myc alters the fate of preneoplastic cells in a mouse model of medulloblastoma." Genes Dev 23, no. 2 (January 15, 2009): 157-170.  Full Text  Link to Item
    • Kessler, JD, Hasegawa, H, Brun, SN, Emmenegger, BA, Yang, Z-J, Dutton, JW, Wang, F, and Wechsler-Reya, RJ. "Erratum: N-myc alters the fate of preneoplastic cells in a mouse model of medulloblastoma (Genes and Development (2009) 23 (157-170))." Genes and Development 23, no. 4 (2009): 535--.
    • Sassa, T, Zhou, X, Han, B-X, Wang, F, and Polleux, F. "Class III phosphatidylinositol 3-kinase (Vps34) is essential for radial neuronal migration in the developing neocortex." Neuroscience Research 65 (January 2009): S46-S46.  Full Text
    • Wang, F. "Axon Guidance: Building Pathways with Molecular Cues in Vertebrate Sensory Systems." (2009): 1073-1079.  Full Text
    • Hasegawa, H, and Wang, F. "Visualizing mechanosensory endings of TrkC-expressing neurons in HS3ST-2-hPLAP mice." The Journal of Comparative Neurology 511, no. 4 (December 2008): 543-556.  Full Text
    • Que, J, Wilm, B, Hasegawa, H, Wang, F, Bader, D, and Hogan, BLM. "Mesothelium contributes to vascular smooth muscle and mesenchyme during lung development." Proceedings of the National Academy of Sciences of the United States of America 105, no. 43 (October 15, 2008): 16626-16630.  Full Text
    • Hasegawa, H, Abbott, S, Han, B-X, Qi, Y, and Wang, F. "Analyzing somatosensory axon projections with the sensory neuron-specific Advillin gene." NEUROSCIENCE RESEARCH 61 (2008): S181-S181.  Link to Item
    • Hasegawa, H, Abbott, S, Han, B-X, Qi, Y, and Wang, F. "Analyzing somatosensory axon projections with the sensory neuron-specific Advillin gene." The Journal of Neuroscience : the Official Journal of the Society for Neuroscience 27, no. 52 (December 2007): 14404-14414.  Full Text
    • Hodge, LK, Klassen, MP, Han, B-X, Yiu, G, Hurrell, J, Howell, A, Rousseau, G, Lemaigre, F, Tessier-Lavigne, M, and Wang, F. "Retrograde BMP signaling regulates trigeminal sensory neuron identities and the formation of precise face maps." Neuron 55, no. 4 (August 2007): 572-586.  Full Text
    • Zhou, X, Babu, JR, da Silva, S, Shu, Q, Graef, IA, Oliver, T, Tomoda, T, Tani, T, Wooten, MW, and Wang, F. "Unc-51-like kinase 1/2-mediated endocytic processes regulate filopodia extension and branching of sensory axons." Proceedings of the National Academy of Sciences of the United States of America 104, no. 14 (April 2007): 5842-5847.  Full Text
    • Graef, IA, Crabtree, GR, and Wang, F. "Calcineurin/NFAT Signaling in Development and Function of the Nervous System." (May 22, 2006): 353-378. (Chapter)  Full Text
    • Wang, F. "Steering growth cones with a CaMKII/calcineurin switch." Neuron 43, no. 6 (September 16, 2004): 760-762.  Full Text  Link to Item
    • Grieshammer, U, Le Ma, , Plump, AS, Wang, F, Tessier-Lavigne, M, and Martin, GR. "SLIT2-mediated ROBO2 signaling restricts kidney induction to a single site." Developmental Cell 6, no. 5 (May 2004): 709-717.  Full Text
    • Graef, IA, Wang, F, Charron, F, Chen, L, Neilson, J, Tessier-Lavigne, M, and Crabtree, GR. "Neurotrophins and netrins require calcineurin/NFAT signaling to stimulate outgrowth of embryonic axons." Cell 113, no. 5 (2003): 657-670.  Full Text
    • Lin, DM, Wang, F, Lowe, G, Gold, GH, Axel, R, Ngai, J, and Brunet, L. "Formation of precise connections in the olfactory bulb occurs in the absence of odorant-evoked neuronal activity." Neuron 26, no. 1 (2000): 69-80.
    • Bulfone, A, Wang, F, Hevner, R, Anderson, S, Cutforth, T, Chen, S, Meneses, J, Pedersen, R, Axel, R, and Rubenstein, JL. "An olfactory sensory map develops in the absence of normal projection neurons or GABAergic interneurons." Neuron 21, no. 6 (December 1998): 1273-1282.  Full Text
    • Wang, F, Nemes, A, Mendelsohn, M, and Axel, R. "Odorant receptors govern the formation of a precise topographic map." Cell 93, no. 1 (1998): 47-60.  Full Text
    • Mombaerts, P, Wang, F, Dulac, C, Chao, SK, Nemes, A, Mendelsohn, M, Edmondson, J, and Axel, R. "Visualizing an olfactory sensory map." Cell 87, no. 4 (November 1996): 675-686.  Full Text
    • Mombaerts, P, Wang, F, Dulac, C, Vassar, R, Chao, SK, Nemes, A, Mendelsohn, M, Edmondson, J, and Axel, R. "The molecular biology of olfactory perception." Cold Spring Harbor Symposia on Quantitative Biology 61 (1996): 135-145.
• Teaching & Mentoring
• 

  Recent Courses

  • NEUROBIO 393: Research Independent Study 2019
  • NEUROBIO 793: Research in Neurobiology 2019
  • NEUROSCI 493: Research Independent Study 1 2019
  • NEUROSCI 755: Interdisciplinary Program in Cognitive Neuroscience (IPCN) Independent Research Rotation 2019
  • NEUROSCI 496: Research Independent Study 4 2018
  • PSY 756: Research Practicum 2018
  • NEUROSCI 150: Research Practicum 2017
  • NEUROSCI 494: Research Independent Study 2 2017
  • NEUROSCI 495: Research Independent Study 3 2017
• Scholarly, Clinical, & Service Activities
• 

  Outreach & Engaged Scholarship

  • Bass Connections Faculty Team Leader. Summer Neuroscience Program Mentor. 2017  2017

Some information on this profile has been compiled automatically from Duke databases and external sources. (Our About page explains how this works.) If you see a problem with the information, please write to Scholars@Duke and let us know. We will reply promptly.