Fang-Fang Yin

Conference Med Phys · May 2022 PURPOSE: To develop a deep learning model design that integrates radiomics analysis for enhanced performance of COVID-19 and non-COVID-19 pneumonia detection using chest x-ray images. METHODS: As a novel radiomics approach, a 2D sliding kernel was implemen ... Full text Link to item Cite

Transfer learning for fluence map prediction in adrenal stereotactic body radiation therapy.

Conference Phys Med Biol · December 6, 2021 Objective:To design a deep transfer learning framework for modeling fluence map predictions for stereotactic body radiation therapy (SBRT) of adrenal cancer and similar sites that usually have a small number of cases.Approach:We developed a transfer learni ... Full text Link to item Cite

A Dosimetric Study Comparing Two Beam Arrangement Strategies in Fractionated Thoracic Spine Stereotactic Body Radiotherapy (SBRT) Planning.

Conference International journal of radiation oncology, biology, physics · November 2021 Purpose/objective(s)To compare dosimetric results of two beam arrangement strategies and their robustness to setup uncertainties in fractionated thoracic spine Stereotactic Body Radiotherapy (SBRT) MATERIALS/METHODS: Fifteen patients who received ... Full text Cite

Radiomics and Outcome Prediction

Conference MEDICAL PHYSICS · June 2021 Link to item Cite

RETRACTED: An Encoder-Decoder Based Deep Learning AI agent for Spatial Dose Distribution Prediction: A Study of Complex Head-and-Neck IMRT Application

Conference International journal of radiation oncology, biology, physics · November 1, 2020 This article has been retracted: please see Elsevier Policy on Article Withdrawal (http://www.elsevier.com/locate/withdrawalpolicy). This abstract has been retracted at the request of the authors. After submitting this abstract the authors realized that th ... Full text Cite

Advances of Radiomics and Genomics in Cancer Management

Conference MEDICAL PHYSICS · June 2020 Link to item Cite

Dose-Distribution-Driven PET Image-Based Outcome Prediction (DDD-PIOP): A Deep Learning Study for Oropharyngeal Cancer IMRT Application

Conference Frontiers in oncology · January 2020 Purpose To develop a deep learning-based AI agent, DDD-PIOP (Dose-Distribution-Driven PET Image Outcome Prediction), for predicting 18FDG-PET image outcomes of oropharyngeal cancer (OPC) in response to intensity-modulated radiation therapy (IMRT). Methods ... Cite

Liver 4D-MRI: An Image Mutual Information based Retrospective Self-sorting Method

Conference 2019 International Conference on Medical Imaging Physics and Engineering Icmipe 2019 · November 1, 2019 Four-dimensional MRI (4D-MRI) is an emerging technique for soft-tissue motion management in radiotherapy treatment planning. The purpose of this study was to develop a novel image mutual information (MI) based retrospective 4DMRI sorting method that is ful ... Full text Cite

Feasibility of radiosurgery dosimetry using NIPAM 3D dosimeters and x-ray CT

Conference Journal of Physics Conference Series · August 29, 2019 We investigated the feasibility of using N-isopropylacrylamide (NIPAM) dosimeters with x-ray CT to verify radiosurgery dose. Dosimeters were prepared at one facility and shipped to a second facility for irradiation. A simulation CT was acquired and plans p ... Full text Cite

Incorporating Case-Based Reasoning for Radiation Therapy Knowledge Modeling: A Pelvic Case Study

Conference Technology in Cancer Research and Treatment · January 1, 2019 Knowledge models in radiotherapy capture the relation between patient anatomy and dosimetry to provide treatment planning guidance. When treatment schemes evolve, existing models struggle to predict accurately. We propose a case-based reasoning framework d ... Full text Cite

Investigation of calibration-based projection domain dual energy decomposition CBCT technique for brain radiotherapy applications

Conference Progress in Biomedical Optics and Imaging Proceedings of SPIE · January 1, 2019 The purpose of the present study was to develop and evaluate a practical dual-energy imaging approach for enhancing on-board cone-beam CT (CBCT) image quality for brain radiotherapy applications. The proposed primary technique involves a projection domain ... Full text Cite

High-resolution imaging immunolabeled large tissues

Conference Optics Infobase Conference Papers · January 1, 2017 We combined large sample resin embedding with immunofluorescence staining to acquire biomolecules profiles with high spatial-resolution. After evaluating the compatibility of this method and filtering embedding resin, we achieved to high-resolution image i ... Full text Cite

A simple, rapid method to precisely locate mRNAs of intact mouse brain via fluorescence tomography

Conference Optics Infobase Conference Papers · January 1, 2017 To precisely locate mRNAs of mouse brain, a simple, rapid method was developed via combining whole mount in situ hybridization and fluorescence tomography, with cytoarchitectonic landmarks provided by propidium iodide real-time counterstaining during the i ... Full text Cite

Physics considerations for single-isocenter, volumetric modulated arc radiosurgery for treatment of multiple intracranial targets.

Conference Pract Radiat Oncol · 2016 OBJECTIVE: Our purpose was to address challenges associated with single-isocenter radiosurgery for multiple intracranial targets (SIRMIT) including increased sensitivity to rotational uncertainties (resulting from distance of the targets from isocenter) as ... Full text Link to item Cite

WE-G-BRD-06: Volumetric Cine MRI (VC-MRI) Estimated Based On Prior Knowledge for On-Board Target Localization.

Conference Med Phys · June 2015 PURPOSE: To develop a technique to generate on-board VC-MRI using patient prior 4D-MRI, motion modeling and on-board 2D-cine MRI for real-time 3D target verification of liver and lung radiotherapy. METHODS: The end-expiration phase images of a 4D-MRI acqui ... Full text Link to item Cite

TH-CD-303-06: Deformable Registration-Based Image Estimation Method for 4D CBCT Using Region-Based PCA.

Conference Med Phys · June 2015 PURPOSE: To investigate the feasibility of using region-based principal component analysis (PCA) for motion modeling to estimate on-board 4D-CBCT using prior information and limited angle projections for potential 4D target verification of lung radiotherap ... Full text Link to item Cite

TH-AB-303-02: An Investigation of Respiratory Signal Parameters for Multiple-Step Ahead Prediction of Surrogate Motion.

Conference Med Phys · June 2015 PURPOSE: Target tracking or gating the radiation beam using real-time imaging and surrogate motion monitoring methods are employed for dynamic tracking treatment or respiratory-gated radiotherapy. This method requires tumor motion prediction far enough in ... Full text Link to item Cite

WE-D-303-05: Dosimetric Accuracy of CBCT Images Estimated by a Motion Modeling and Free-Form Deformation Technique for Radiotherapy of Lung Cancer.

Conference Med Phys · June 2015 PURPOSE: To investigate the dosimetric accuracy of CBCTs estimated by a motion modeling and free-form deformation(MM-FD) technique for radiotherapy of lung cancer. METHODS: Various inter-fractional variations featuring patient motion pattern change, tumor ... Full text Link to item Cite

WE-AB-303-09: Rapid Projection Computations for On-Board Digital Tomosynthesis in Radiation Therapy.

Conference Med Phys · June 2015 PURPOSE: To facilitate fast and accurate iterative volumetric image reconstruction from limited-angle on-board projections. METHODS: Intrafraction motion hinders the clinical applicability of modern radiotherapy techniques, such as lung stereotactic body r ... Full text Link to item Cite

SU-E-T-293: Dosimetric Analysis of Microscopic Disease in SBRT for Lung Cancers.

Conference Med Phys · June 2015 PURPOSE: To evaluate the dosimetry of microscopic disease (MD) region of lung cancer in stereotactic body radiation therapy (SBRT). METHODS: For simplicity, we assume organ moves along one dimension. The probability distribution function of tumor position ... Full text Link to item Cite

SU-E-J-26: A Novel Technique for Markerless Self-Sorted 4D-CBCT Using Patient Motion Modeling: A Feasibility Study.

Conference Med Phys · June 2015 PURPOSE: To develop an automatic markerless 4D-CBCT projection sorting technique by using a patient respiratory motion model extracted from the planning 4D-CT images. METHODS: Each phase of onboard 4D-CBCT is considered as a deformation of one phase of the ... Full text Link to item Cite

SU-E-I-40: Phantom Research On Monochromatic Images Taken by Dual CBCT with Multiple Energy Sets.

Conference Med Phys · June 2015 PURPOSE: To evaluate the quality of monochromatic images at the same virtual monochromatic energy using dual cone-beam computed tomography (CBCT) with either kV/kV or MV/kV or MV/MV energy sets. METHODS: CT images of Catphan 504 phantom were acquired using ... Full text Link to item Cite

MO‐G‐304‐03: Development of Knowledge Models for IMRT Treatment Planning Utilizing a Rapid Learning Approach

Conference Medical Physics · June 2015 Purpose:We present an implementation of the knowledge‐based planning method utilizing a rapid learning approach which enables the accurate evolution of models as new data are collected during daily clinical practi ... Full text Cite

TH-CD-303-12: Sliding Motion Compensated Simultaneous 4D-CBCT Reconstruction

Conference Medical Physics · June 2015 Full text Cite

Knowledge modeling for computer aided treatment planning

Conference Ifmbe Proceedings · January 1, 2015 The purpose for this study is to develop robust and comprehensive knowledge models which can provide patient specific prediction of achievable dose distribution in radiation therapy plans for a wide range of cancer types. These models are useful tools to g ... Full text Cite

Knowledge based automatic beam angle determination for lung IMRT planning

Conference Ifmbe Proceedings · January 1, 2015 We present an efficient knowledge based automatic beam configuration determination method by utilizing patient-specific anatomy and tumor geometry information and a beam bouquet atlas. The proposed technique is based on learning the relationship between pa ... Full text Cite

A rapid learning approach for the knowledge modeling of radiation therapy plan

Conference Ifmbe Proceedings · January 1, 2015 The purpose of this study is to implement a rapid learning method to train the knowledge models to predict the organ-at-risk (OAR) dose sparing in radiation therapy (RT) based on an array of patient anatomical features. We also aim to establish the evaluat ... Full text Cite

Automatic Determination of Beam Angles in Lung IMRT Planning

Conference International Journal of Radiation Oncology*Biology*Physics · September 2014 Full text Cite

Feasibility of Using a Fourier Markerless Technique for Clinical 4D-CBCT Reconstruction

Conference International Journal of Radiation Oncology*Biology*Physics · October 2013 Full text Cite

Incorporating Trade-Off in Knowledge Modeling of Parotid Dose Sparing in Head and Neck IMRT

Conference International Journal of Radiation Oncology*Biology*Physics · October 2013 Full text Cite

Quality Evaluation of an Automatic VMAT Planning Method for Head-and-Neck Cancer Cases

Conference International Journal of Radiation Oncology*Biology*Physics · October 2013 Full text Cite

Effects of PET Reconstruction Parameters on Region-of-Interest Contouring by SUV Threshold

Conference International Journal of Radiation Oncology*Biology*Physics · October 2013 Full text Cite

Modeling Organs at Risk Dose Sparing in Head and Neck Tomotherapy and IMRT Plans: A Comparison Study

Conference International Journal of Radiation Oncology*Biology*Physics · October 2013 Full text Cite

Normal Tissue Toxicity Criteria in Radiation Therapy

Conference International Journal of Radiation Oncology*Biology*Physics · October 2013 Full text Cite

Quantitative Comparison of Knowledge-Guided IMRT Planning to Expert Planning for Prostate Cancer

Conference International Journal of Radiation Oncology*Biology*Physics · October 2013 Full text Cite

Intertechnique and Interinstitutional Modeling of the Dosimetry of Organs-at-Risk in Head and Neck IMRT Plans

Conference International Journal of Radiation Oncology*Biology*Physics · October 2013 Full text Cite

SU-E-T-196: Pretreatment Patient Clinical Objective IMRT Quality Assurance Using a 3D Diode Array.

Conference Med Phys · June 2013 PURPOSE: To evaluate the accuracy and sensitivity of a patient clinical objective IMRT QA tool using a 3D diode array. METHODS: A 3D QA device (Delta4, Scandidos Inc.) with 2 orthogonal diode array planes was used for IMRT QA. The diode spacing is 5mm in c ... Full text Link to item Cite

WE-G-108-08: A Novel Technique for VMAT QA with EPID in Cine Mode On Varian TrueBeam.

Conference Med Phys · June 2013 PURPOSE: Volumetric modulated arc therapy (VMAT) is a relatively new treatment modality for dynamic photon radiation therapy. Pre-treatment quality assurance (QA) is necessary and many efforts have been taken to apply electronic portal imaging device (EPID ... Full text Link to item Cite

MO-F-WAB-11: Investigation of CBCT-Based Patient Positioning Accuracy in Lung SBRT: Correlation with Breathing Irregularity.

Conference Med Phys · June 2013 PURPOSE: To evaluate breathing irregularity induced error in CBCT-based patient positioning in lung SBRT and correlate the error with a measure of breathing variability. METHODS: The 4D extended cardiac-torso (XCAT) digital phantom was used to generate 10- ... Full text Link to item Cite

SU-E-T-560: A Method to Determine Optimal Dynamic MLC Parameters for Varian Truebeam with Millennium MLC and HDMLC.

Conference Med Phys · June 2013 PURPOSE: Correct MLC modeling is essential to the accurate IMRT delivery. Most TPSs use simplified models with parameters of leaf transmission (LT) and dynamic leaf gap (DLG). The common way to determine them is through extrapolation from measurements. In ... Full text Link to item Cite

WE-A-134-04: Comprehensive Evaluation of a Respiration-Phase-Matched Digital Tomosynthesis (DTS) Imaging Technique for Monitoring Moving Targets.

Conference Med Phys · June 2013 PURPOSE: To develop a respiration-phase-matched DTS technique to monitor moving targets, and to evaluate its accuracy for various imaging parameters and anatomical characteristics Methods: Conventional methods, registering on-board DTS(OB-DTS, reconstructe ... Full text Link to item Cite

TU-G-141-03: An On-Board 4D-CBCT Reconstruction Technique Using Limited-Angle Projections Based On Motion Modeling and Free-Form Deformation (MM-FD).

Conference Med Phys · June 2013 PURPOSE: To develop an on-board 4D-CBCT(OB-4D-CBCT) reconstruction technique using prior information and limited-angle projections for 4D inter/intra-fractional target verificationMethods: The OB-4D-CBCT at each phase is considered as a deformation of plan ... Full text Link to item Cite

SU-E-T-602: Dynamic Electron Arc Radiotherapy (DEAR): A Planning Study.

Conference Med Phys · June 2013 PURPOSE: Electron beam therapy is under-utilized in radiation treatment of cancer and has remained practically unchanged for decades. We propose a new technique, Dynamic Electron Arc Radiotherapy (DEAR) with synchronized couch motion. In DEAR, gantry rotat ... Full text Link to item Cite

Phase/Amplitude-matched Digital Tomosynthesis (DTS) Imaging for Moving Target Localization.

Conference Pract Radiat Oncol · 2013 Full text Link to item Cite

TH‐A‐WAB‐04: Respiratory Sorted Imaging Using Region‐Of‐Interest Robotic Multi‐Pinhole SPECT System

Conference Medical Physics · January 1, 2013 Purpose: Single Photon Emission Computed Tomography (SPECT) may provide important information on tumors in the thorax and abdomen. Respiratory sorted imaging using conventional full cross‐section methods is generally degraded by noise. The purpose is to in ... Full text Cite

WE‐G‐500‐09: Robotic Multi‐Pinhole Scenarios for SPECT Molecular and Functional Imaging Onboard and in Other Applications

Conference Medical Physics · January 1, 2013 Purpose: Single Photon Emission Computed Tomography (SPECT) is one of the two predominant modes of nuclear emission tomography, the other being Positron Emission Tomography (PET). An important recent advance has been region‐of‐interest (ROI) SPECT for card ... Full text Cite

SU‐E‐J‐200: Impact of FDG‐PET/CT Reconstruction Parameters On PET Variability and Treatment Response Assessment

Conference Medical Physics · January 1, 2013 Purpose: To examine the effect of PET image reconstruction parameters on baseline and early‐treatment FDG‐PET/CT quantitative imaging. Early‐treatment changes in tumor metabolism in primary tumor and nodes can potentially determine if the patient is respon ... Full text Cite

SU‐E‐T‐474: Adaptive Stereotactic Body Radiation Therapy (SBRT) Planning for Lung Cancer: Can We Predict Who Will Benefit?

Conference Medical Physics · January 1, 2013 Purpose: We have previously shown that adaptive lung SBRT planning can mitigate dose to adjacent organs at risk (OARs). The aim of this study is to investigate factors that affect dosimetric effectiveness of adaptive lung SBRT, so that we may predict which ... Full text Cite

TU‐C‐141‐08: Evaluate Deformable Image Registration for the Lungs Using Hyperpolarized Gas Tagging MRI

Conference Medical Physics · January 1, 2013 Purpose: To evaluate deformable image registration for the lungs using hyperpolarized gas MR tagging technique.Method and Materials: A 3D MR grid‐tagging technique using hyperpolarized helium‐3 (HP‐He3) as gaseous contrast was developed for direct measurem ... Full text Cite

SU‐E‐J‐150: Investigation of Feasibility of Concurrent Orthogonal KV and MV X‐Ray Imaging for Tagrget Tracking During Dose Delivery for Stereotactic Body Radiotherapy (SBRT): A Pilot Phantom Study

Conference Medical Physics · January 1, 2013 Purpose: To investigate feasibility of motion tracking using concurrent orthogonal kV and MV x‐ray images acquired during dose delivery for stereotactic body radiotherapy (SBRT).Method and Materials: The study was performed on a Varian TrueBeam treatment u ... Full text Cite

SU‐E‐CAMPUS‐J‐04: Evaluating Radiation‐Induced Changes with Diffusion Weighted MRI and Dynamic Contrast Enhanced MRI in Patients with Early Stage Breast Cancer Treated with Stereotactic Body Radiotherapy: Initial Results

Conference Medical Physics · January 1, 2013 Purpose: Pre‐operative stereotactic body radiosurgery (SBRT) was delivered in a single fraction to treat patients with early stage breast cancer; however, few data are available regarding radiation‐induced changes by SBRT. In this work, diffusion weighted ... Full text Cite

SU‐E‐T‐707: Evaluation of the Quality of Organs‐At‐Risk Dose Sparing in Anorectal and Prostate IMRT Plans

Conference Medical Physics · January 1, 2013 Purpose: To evaluate the quality of organs‐at‐risk (OARs) dose sparing in IMRT plans for anorectal and prostate cancer cases utilizing organ‐based knowledge models to predict OAR DVHs.MethodsThe quality of OAR dose sparing in IMRT plans are evaluated by or ... Full text Cite

TH‐C‐137‐08: Dosimetric Quality of An Automatic IMRT Planning Method for Head and Neck Cancer Cases

Conference Medical Physics · January 1, 2013 Purpose: To evaluate the dosimetric quality of an automatic IMRT planning method for Head and Neck (HN) cancer cases. Methods: Eighteen HN cancer patients are planned with nine equally spaced IMRT beams. The OAR dose sparing objectives for each plan (prima ... Full text Cite

SU‐E‐CAMPUS‐T‐05: Quality Evaluation of An Automatic VMAT Planning Method for Head and Neck Cancer Cases

Conference Medical Physics · January 1, 2013 Purpose: To evaluate the dosimetric quality of an automatic volumetric‐modulated arc therapy (VMAT) planning method for Head and Neck (HN) cancer cases. Methods: Eighteen HN cancer cases are planned automatically by 2‐arc VMAT. An OAR DVH prediction model ... Full text Cite

TU‐E‐108‐02: Dynamic Electron Arc Radiotherapy (DEAR): A Feasibility Study

Conference Medical Physics · January 1, 2013 Purpose: Electron beam therapy is under‐utilized in radiation treatment of cancer and has remained practically unchanged for decades. We propose a new technique, Dynamic Electron Arc Radiotherapy (DEAR) with synchronized couch motion. DEAR utilizes modulat ... Full text Cite

SU‐E‐J‐91: Developing Platform for Online Registration Using Digital Tomosynthesis

Conference Medical Physics · January 1, 2013 Purpose: To meet the needs of fast registration of on‐board digital tomosynthesis (DTS), a platform was developed in assisting the task of intensive DTS reconstruction and analysis. Methods: this platform consists of four parts: pre‐processing, reconstruct ... Full text Cite

The effect of motion on IMRT - looking at interplay with 3D measurements.

Conference J Phys Conf Ser · 2013 Six base of skull IMRT treatment plans were delivered to 3D dosimeters within the RPC Head and Neck Phantom for QA verification. Isotropic 2mm 3D data was obtained using the DLOS-PRESAGE system and compared to an Eclipse (Varian) treatment plan. Normalized ... Full text Link to item Cite

Generation of Virtual Monochromatic (VM) CBCT from Dual kV/MV Beam Projections

Conference International Journal of Radiation Oncology*Biology*Physics · November 2012 Full text Cite

Functional and Molecular Imaging of the Axilla as the Patient Is in Position for Radiation Therapy Using a Robotic Multi-pinhole SPECT System

Conference International Journal of Radiation Oncology*Biology*Physics · November 2012 Full text Cite

Dosimetric Evaluation of Flattening Filter-free (FFF) Photon Beams for Lung SBRT

Conference International Journal of Radiation Oncology*Biology*Physics · November 2012 Full text Cite

Impact of Patient Anatomy Variations on a Fourier Technique for Markerless 4D-CBCT

Conference International Journal of Radiation Oncology*Biology*Physics · November 2012 Full text Cite

Prostate SBRT in 5 Fractions: Initial Report on Dosimetric Results and IGRT Experiences

Conference International Journal of Radiation Oncology*Biology*Physics · November 2012 Full text Cite

Knowledge-based Organ-at-Risk Sparing Models and Individualized Trade-offs in Intensity Modulated Radiation Therapy Planning

Conference International Journal of Radiation Oncology*Biology*Physics · November 2012 Full text Cite

Can Standard Radiation Therapy Quality Assurance (QA) Detect Potential Delivery Errors?

Conference International Journal of Radiation Oncology*Biology*Physics · November 2012 Full text Cite

Evaluation of IMRT and VMAT for Head-and-Neck Cancer With Flattening Filter-free (FFF) Beams

Conference International Journal of Radiation Oncology*Biology*Physics · November 2012 Full text Cite

Partial Breast Extracranial Radiosurgery: A Dosimetric Evaluation of Treatment Delivery Accuracy

Conference International Journal of Radiation Oncology*Biology*Physics · November 2012 Full text Cite

Assessing Effects of Ion Collection Efficiency in Flattening Filter-Free (FFF) Beams On Three TrueBeam Machines

Conference MEDICAL PHYSICS · June 2012 Full text Link to item Cite

Dual-Energy CBCT Imaging for Metal Artifact Reduction and Contrast Enhancement

Conference MEDICAL PHYSICS · June 2012 Full text Link to item Cite

A Fourier Technique for Markerless, Self-Sorted 4D-CBCT: Effect of Respiratory Characteristics

Conference MEDICAL PHYSICS · June 2012 Full text Link to item Cite

Evaluating Radiation-Induced White Matter Changes in Patients with Recurrent Malignant Gliomas Under Treatment of Stereotactic Radiosurgery Using Diffusion Tensor Imaging

Conference MEDICAL PHYSICS · June 2012 Full text Link to item Cite

Phase-Matched Digital Tomosynthesis (DTS) Imaging for Simultaneous Target Verification During Volumetric Modulated Arc Therapy (VMAT) Treatment

Conference MEDICAL PHYSICS · June 2012 Full text Link to item Cite

Benchmarking Flattening-Filter Free Photons for IMRT/VMAT

Conference MEDICAL PHYSICS · June 2012 Full text Link to item Cite

A Protocol for Comprehensive Acceptance/Commissioning of Complex 3D QA Devices

Conference MEDICAL PHYSICS · June 2012 Full text Link to item Cite

Experimental Measurements of 3D Dose Distribution for a Moving Target Treated with IMRT and VMAT

Conference MEDICAL PHYSICS · June 2012 Full text Link to item Cite

Contrast-To-Noise Ratio (CNR) Enhancement and Lag Correction in Cone Beam CT (CBCT) Using a Synchronized-MOving-Grid (SMOG) System

Conference MEDICAL PHYSICS · June 2012 Full text Link to item Cite

SU-E-T-406: Online Image-Guidance for Prostate SBRT: Dosimetric Benefits and Margin Analysis.

Conference Med Phys · June 2012 PURPOSE: To evaluate the dosimetric benefits of online image guidance during prostate stereotactic body radiotherapy (SBRT) and the potential on margin reduction. METHODS: 28 prostate SBRT patients were retrospectively studied, each treated with 37Gy in 5 ... Full text Link to item Cite

SU-E-T-626: Individualized Trade-Off of Dose Coverage and Sparing in IMRT Planning.

Conference Med Phys · June 2012 PURPOSE: We present an evidence-based approach to quantifying the dose sparing trade-offs between different Organs-at-risk (OARs) and the trade-off between OAR dose sparing and target dose coverage in IMRT plans. METHODS: The interaction between dose spari ... Full text Link to item Cite

MO-D-BRB-10: Modeling Inter-Patient Variation of Organ-At-Risk Sparing in IMRT Plans: An Evidence-Based Plan Quality Evaluation.

Conference Med Phys · June 2012 PURPOSE: To develop a predictive model to assess the quality of critical organ dose sparing in IMRT plans by providing patient specific dose sparing references, based on an array of patient anatomical features and prior planning experience. METHODS: Contri ... Full text Link to item Cite

TU‐A‐213CD‐04: A Novel Technique for Estimating and Correcting Cross‐Scatter in Dual‐Source CBCT

Conference Medical Physics · January 1, 2012 Purpose: Dual‐source CBCT may provide several advantages over current on‐board 3D localization techniques; however, dual‐source CBCT suffers greatly from cross‐scatter. A novel technique was developed that includes sampling the cross‐scatter only projectio ... Full text Cite

TH‐E‐BRA‐01: A Line‐Source Method for Aligning Onboard‐Robotic‐Pinhole and Other SPECT‐Pinhole Systems

Conference Medical Physics · January 1, 2012 Purpose: To achieve on‐board molecular imaging in the radiation therapy room, we are developing a robotic multi‐pinhole SPECT system. Alignment of the SPECT system to LINAC/CBCT coordinates is essential for target localization and image reconstruction. Pin ... Full text Cite

TU‐A‐BRA‐01: A Robotic Multi‐Pinhole SPECT System for Onboard and Other Region‐Of‐Interest Imaging

Conference Medical Physics · January 1, 2012 Purpose: Radiation therapy beam guidance and modulation at treatment time could be substantially supported by onboard molecular and functional imaging capability. Currently there is very little range of technology available for this. Herein we propose and ... Full text Cite

WE‐C‐213CD‐01: Decision Support for Radiation Therapy

Conference Medical Physics · January 1, 2012 Informatics in radiation therapy is less understood. Decision support for, or knowledge‐guided, radiation therapy, is a major component of informatics, where the data is mined, modeled and turned into computable knowledge. It is critically important for ra ... Full text Cite

TH‐C‐BRB‐01: Credentialing Results from a Spine Anthropomorphic Phantom

Conference Medical Physics · January 1, 2012 Purpose: To use an anthropomorphic spine phantom for dosimetric credentialing purposes in National Cancer Institute sponsored clinical trials. Methods: An anthropomorphic spine phantom that consists of lungs, a heart, an esophagus, a spinal cord, vertebrae ... Full text Cite

Dosimetric Evaluation and Optimization of a Novel CBCT Estimation Method for Adaptive Radiation Therapy (ART)

Conference International Journal of Radiation Oncology*Biology*Physics · October 2011 Full text Cite

909 INDUCTION OF RADIATION-INDUCED ERECTILE DYSFUNCTION OF RAT AFTER PROSTATE-CONFINED MODERN RADIOTHERAPY

Conference Journal of Urology · April 2011 Full text Cite

WE‐E‐301‐01: Practical Tips for VMAT Implementation

Conference Medical Physics · January 1, 2011 Volumetric modulated arc therapy (VMAT) is an arc‐based dose delivery approach that produces highly conformal dose distributions similar to those generated with static gantry intensity modulated radiation therapy. Like many existing IMRT approaches, this t ... Full text Cite

SU‐E‐T‐98: VMAT Quality Assurance: Improving the Angular Correction Factors for Ion Chamber Arrays

Conference Medical Physics · January 1, 2011 Purpose: Two‐dimensional (2D) detector arrays for QA of volumetric‐modulated‐arc‐therapy (VMAT) plans show angular dependence. An angular correction‐factor‐table (CFs) minimize this effect, but assumes: (1) the response of all ion chambers (IC) is identica ... Full text Cite

SU‐E‐J‐22: Measurement‐Based Cross‐Scatter Correction in Dual Detector Cone‐Beam CT

Conference Medical Physics · January 1, 2011 Purpose: A dual detector cone‐beam CT (CBCT) system could potentially allow for dual energy CBCT and dual‐view DTS. However, image quality in this system is severely degraded by the presence of scatter between the two imaging chains, i.e. cross‐scatter. Th ... Full text Cite

SU‐C‐214‐06: Noise Power Properties of a Dual‐Detector Cone‐Beam CT System

Conference Medical Physics · January 1, 2011 Purpose: Very little information is available for noise properties using a dual‐detector cone‐beam CT (CBCT) system. Geometric misalignment, cross‐scatter, and inhomogeneous detector response are additional concerns in a dual‐detector system. This study ch ... Full text Cite

SU‐E‐J‐180: SPECT‐Based Target Localization: Comparison between Full‐Size and Compact Detectors

Conference Medical Physics · January 1, 2011 Purpose: Single photon emission computed tomography (SPECT) is being investigated for imaging inside radiation therapy (RT) treatment rooms to target tumor biology. Because of the space occupied by RT devices and the size and weight of typical gamma camera ... Full text Cite

TU‐E‐BRC‐08: Investigation of Anatomical Surrogate for 4DCT Imaging

Conference Medical Physics · January 1, 2011 Purpose: Respiratory signal for 4DCT is typically extracted using an external respiratory positioning management device (RPM) which is often inconvenient and time consuming. The efficiency of 4DCT imaging could be substantially improved if anatomical body ... Full text Cite

SU‐E‐I‐29: A Prior Information Based Total‐Variation Digital Tomosynthesis Reconstruction Algorithm

Conference Medical Physics · January 1, 2011 Purpose: To develop a total‐variation (TV) based compressive sensing image reconstruction algorithm using a set of limited‐angle projections by applying a prior image information to enhance the image quality and anatomic information of current Four‐d ... Full text Cite

MO‐D‐214‐01: 4D‐MRI for Radiation Therapy of Moving Tumors

Conference Medical Physics · January 1, 2011 Four‐dimensional computed tomography (4D‐CT) has been widely used in radiation therapy for imaging moving tumors, especially in the thoracic regions. In other body sites such as the abdominal, 4D‐CT is limited due to its intrinsic low soft‐tissue contrast. ... Full text Cite

MO‐D‐BRB‐03: Investigation of the Reproducibility of Probability Distribution function (PDF) of Tumor Motion in Lung Stereotactic Body Radiation Therapy (SBRT)

Conference Medical Physics · January 1, 2011 Purpose: To investigate the reproducibility of probability distribution function (PDF) of lung tumor motion using cine‐MV images from lung SBRT treatments. Findings of the study will provide valuable information for probability‐based treatment planning. Me ... Full text Cite

SU‐E‐T‐123: Evaluation of Integrated Gating Systems on a Novalis Tx System Using Quantitative Motion Tracking Analyses and Efficient Time‐Delay Measurements

Conference Medical Physics · January 1, 2011 Purpose: To investigate accuracy of motion tracking and radiation delivery controlling of integrated gating systems on a Novalis Tx system. Methods: The study was performed on a Novalis Tx system, which is equipped with Varian RPM and BrainLAB ExacTrac gat ... Full text Cite

SU‐F‐BRA‐10: A Novel Technique for Markerless Self‐Sorted 4D‐CBCT

Conference Medical Physics · January 1, 2011 Purpose: Four‐dimensional (4D) imaging in the radiotherapy treatment room can provide verification of moving targets, which allows for potential reduction of margins and consequent dose escalation. 4D‐CBCT acquisition requires correlation between projectio ... Full text Cite

MO‐F‐211‐04: Fast Phase Contrast MR Angiography with Simplified Skipped Phase Encoding and Edge Deghosting with Array Coil Enhancement (S‐ SPEED‐ACE)

Conference Medical Physics · January 1, 2011 Purpose: The aim of this work is to investigate the feasibility of accelerating phase contrast MR angiography by the fast imaging method of Simplified Skipped Phase Encoding and Edge Deghosting with Array Coil Enhancement (S‐SPEED‐ACE). Methods: The parall ... Full text Cite

SU‐E‐T‐99: A Patient Specific QA Protocol for Verification of 4D Dosimetry

Conference Medical Physics · January 1, 2011 Purpose: Presently, there is no patient specific dosimetric QA for radiation treatment of moving targets. Here we present a patient specific QA protocol for verification of 4D dosimetry delivered to a moving target in SBRT of lung and liver tumors. Methods ... Full text Cite

MO‐D‐BRC‐01: Dosimetric Evaluation of a Novel Cone‐Beam CT (CBCT) Estimation Method Using Prior Information for Lung Cancer Patient Treatment

Conference Medical Physics · January 1, 2011 Purpose: To evaluate the dosimetric accuracy of a novel CBCT estimation method using prior information for use in adaptive radiotherapy (ART)‐based treatment of lung cancer patients. Methods: Patient planning CT or previous day's CBCT images are used as th ... Full text Cite

SU‐C‐110‐01: Strategies for Online Plan Re‐Optimization: Objective Settings and Starting Stage

Conference Medical Physics · January 1, 2011 Purpose: To find the most robust strategies of objective setting and starting stage for online plan re‐optimization, so it can be automatically executed within 1 min while providing high quality adaptive plans. Methods: 10 prostate cancer patients, each wi ... Full text Cite

SU‐E‐T‐860: Developing a Fast‐Monotonic Descent (FMD) Algorithm for RapidArc Radiotherapy

Conference Medical Physics · January 1, 2011 Purpose: To develop a fast‐monotonic descent (FMD) algorithm for optimization of VMAT treatment planning, and investigate the impacts of arc numbers and beam interval on the plan dose quality. Methods: Fast‐monotonic descent (FMD) algorithm, proved to be o ... Full text Cite

SU‐E‐T‐854: Key Anatomical Factors Influencing OAR Dose‐Volume Distribution in Prostate IMRT Plans

Conference Medical Physics · January 1, 2011 Purpose: To identify the key factors of patient anatomy that influence the optimal dose volume histograms (DVHs) for the organs‐at‐risk (OARs) and to explore the tradeoffs between different OAR sparing goals. Methods: 88 prostate IMRT plans were studied re ... Full text Cite

TH‐E‐BRB‐05: Modeling the Correlation Between OAR Dose Sparing and Patient's Anatomy in Head and Neck IMRT

Conference Medical Physics · January 1, 2011 Purpose: To summarize the knowledge of the dependence of organ‐at‐risk (OAR) dose‐volume distribution on patient's anatomy by machine learning techniques from a database of previous expert plans. Methods: 35 head‐and‐ neck IMRT plans were studied retrospec ... Full text Cite

Phase Window and Frame Rate Optimization for On-board 4D Imaging Dose Reduction

Conference International Journal of Radiation Oncology*Biology*Physics · November 2010 Full text Cite

Reduced Cross Scatter in Dual-source Cone-Beam CT by Asynchronous Projection Acquisition

Conference International Journal of Radiation Oncology*Biology*Physics · November 2010 Full text Cite

Potentially Underestimating the Internal Target Volume (ITV) in Free-Breathing Cone-Beam CT (CBCT)

Conference International Journal of Radiation Oncology*Biology*Physics · November 2010 Full text Cite

On-board SPECT for Target Localization: A Comprehensive Analysis of Findings from Computer Simulation and Scanner Studies

Conference International Journal of Radiation Oncology*Biology*Physics · November 2010 Full text Cite

Extracting Breathing Signal from Image Fourier Transform for Developing 4D-MRI

Conference International Journal of Radiation Oncology*Biology*Physics · November 2010 Full text Cite

Cone-Beam CT 6 Degree-of-Freedom Image-Guidance for Intracranial Frameless Stereotactic RadioSurgery using 6D Robotic Couch

Conference International Journal of Radiation Oncology*Biology*Physics · November 2010 Full text Cite

Stereotactic Body Radiotherapy (SBRT) in Patients Previously Treated with External Beam Radiation Therapy

Conference International Journal of Radiation Oncology*Biology*Physics · November 2010 Full text Cite

A Modern Animal Model of Radiation-induced Erectile Dysfunction

Conference International Journal of Radiation Oncology*Biology*Physics · November 2010 Full text Cite

Intensity Modulated Arc Therapy: Effective and Efficient End-to-end Patient Specific Quality Assurance

Conference International Journal of Radiation Oncology*Biology*Physics · November 2010 Full text Cite

Breast Cancer Radiation Treatment Planning: A Comparison of Anisotropic Analytical Algorithm (AAA) and Pencil Beam Convolution (PBC) Algorithm

Conference International Journal of Radiation Oncology*Biology*Physics · November 2010 Full text Cite

Variation of Clinically Relevant Dose Indices for 3DCRT of Lung with Respect to Dose Calculation Algorithm

Conference International Journal of Radiation Oncology*Biology*Physics · November 2010 Full text Cite

SU‐GG‐I‐140: Maximum Intensity Projection (MIP) Imaging Using Multi‐Slice Cine MRI

Conference Medical Physics · January 1, 2010 Purpose: To propose a novel method of acquiring Maximum Intensity Projection (MIP) images using multi‐slice cine MRI, termed as MRI‐MIP, and to evaluate its feasibility in quantifying motion magnitude. Materials and Methods: MRI‐MIP images are acquired usi ... Full text Cite

SU‐GG‐T‐483: Does Breath‐Hold Immobilization Affect Tumor Radioresistance in Breast?

Conference Medical Physics · January 1, 2010 Purpose: A 15–30s Breath Hold (BH) is often used in radiation therapy for breast cancer patients to minimize heart dose, however its effect on tumor oxygenation and radiosensitivity is unknown. The purpose of this study is to utilize published data on the ... Full text Cite

TU‐A‐204B‐04: A Technique to Correct Crescent Artifacts in On‐Board CBCT

Conference Medical Physics · January 1, 2010 Purpose: Large dark and bright crescents are commonly seen in cone‐beam (CB) CT images acquired onboard radiation therapy machines. The purpose of this project is to develop a technique for removing this artifact. Method and Materials: We propose that cres ... Full text Cite

TU‐C‐204B‐06: Performance Evaluation of a Dual Cone‐Beam CT (Dual CBCT) System

Conference Medical Physics · January 1, 2010 Purpose: Very little information is available for clinical CBCT imaging using a dual‐detector system. This study assesses the performance of a recently developed bench‐top dual large‐flat‐panel detectors cone beam computed tomography (CBCT) system and to c ... Full text Cite

SU‐GG‐J‐80: Characterization of Cross Scatter in Dual Source CBCT

Conference Medical Physics · January 1, 2010 Purpose: A dual‐source CBCT imaging system provides an efficient means to perform 3D and 4D imaging, but the addition of the second imaging chain produces additional scattered photons or cross scatter. The purpose of this study is to characterize cross sca ... Full text Cite

SU‐GG‐T‐136: Treatment Plans Comparison with Static‐Gantry IMRT and RapidArcTM for Head‐And‐Neck Cancers Involving Cervical Lymph Nodes

Conference Medical Physics · January 1, 2010 Purpose: To compare the dosimetric results and treatment efficiency of intensity modulated arc therapy using RapidArc™ to static‐gantry IMRT plans for conventional fractionation treatment of head‐and‐neck cancer. Materials and Methods: This study evaluated ... Full text Cite

SU‐GG‐T‐530: Comparison of Coplanar and Non‐Coplanar Intensity Modulated Arc Techniques for Treatment of Intracranial Multi‐Focal Stereotactic Radiosurgery

Conference Medical Physics · January 1, 2010 Objectives: Intensity modulated arc therapy (IMAT) can potentially be a useful technique for the treatment of multi‐focal intracranial stereotactic radiosurgery (SRS) with a single isocenter setup. This study compares the effects of coplanar and non‐coplan ... Full text Cite

SU‐GG‐J‐67: Evaluating Dynamic Magnetic Resonance Imaging Using a New Design of Phantom: Validation with Fast Megavoltage Fluoroscopic Imaging

Conference Medical Physics · January 1, 2010 Purpose: To devlope a reliable and economic phantom for motion management study and investigate its feasibility in evaluating dynamic MRI. Method and Materials: Experiments was performed using an in‐house developed phantom that consists of a platform, a lo ... Full text Cite

TU‐B‐201B‐02: Self‐Sorted Four‐Dimensional CT Using Body Volume as Respiratory Surrogate

Conference Medical Physics · January 1, 2010 Purpose: To develop a self‐sorting four‐dimensional CT (4D‐CT) technique that uses body volume as the respiratory surrogate. Method and Materials: Respiratory signals are determined by the changes in body volume at each slice location as a function of imag ... Full text Cite

SU‐GG‐I‐148: Self‐Sorted Four‐Dimensional Magnetic Resonance Imaging: A Feasibility Study

Conference Medical Physics · January 1, 2010 Purpose: Considerable imaging dose to health tissue of patient from 4D‐CT is often a concern. This study is to develop a four‐dimensional magnetic resonance imaging (4D‐MRI) technique based on retrospective sorting strategy that uses body volume as respira ... Full text Cite

SU‐GG‐I‐24: Improving IGRT Efficiency Using GPU‐Based Ultrafast Reconstruction of DTS/CBCT and DRR

Conference Medical Physics · January 1, 2010 Purpose: One challenge of on‐line image‐guided radiation therapy is requirement of immediate availability of reconstructed 3D or 4D images for evaluation. This study is to develop a highly data‐parallel version and platform of accelerating reconstruction f ... Full text Cite

SU‐GG‐J‐62: Use Winston‐Lutz Test to Check Cone Beam CT Isocenter Accuracy for Imaging Guided Intracranial Stereotactic Radiosurgery

Conference Medical Physics · January 1, 2010 Objectives: Cone beam CT (CBCT) opens the era of three dimensional (3D) imaging guided stereotactic radiosurgery (SRS). The CBCT isocenter accuracy is critical for imaging guided SRS guidance. This study analyzes the daily quality assurance (QA) results of ... Full text Cite

SU‐GG‐I‐144: Accelerating Non‐Contrast‐Enhanced MRA with Inflow Inversion Recovery by Using Skipped Phase Encoding and Edge Deghosting (SPEED)

Conference Medical Physics · January 1, 2010 Purpose: Non‐contrast‐enhanced MR angigraphy (MRA) has always been a valuable clinical tool to study vasculatural diseases. The recently arising concerns of constrast agents in contrast‐enhanced MRA encouraged more use of non‐contrast‐enhanced MRA. The aim ... Full text Cite

SU‐GG‐T‐225: Gantry‐Angle Dependence of a 2D Ion Chamber Array for IMAT QA

Conference Medical Physics · January 1, 2010 Purpose: Gantry‐angle dependence of dose measurement for intensity‐modulated arc therapy (IMAT) quality assurance (QA) using a two‐dimensional ion chamber array may be significant. A new device, the gantry angle sensor, has been provided to compensate for ... Full text Cite

SU‐GG‐T‐137: Similarities between Static and Rotational Intensity Modulated Plans

Conference Medical Physics · January 1, 2010 Purpose: To explore similarities between intensity modulated radiotherapy (IMRT) and intensity modulated arc therapy (IMAT) techniques in the context of the number of multi‐leaf collimator (MLC) segments required to achieve plan objectives, the major facto ... Full text Cite

SU‐GG‐T‐583: Dosimetric Comparison of Anisotropic Analytical and Pencil Beam Convolution Algorithms in Breast Cancer Radiation Treatment Planning

Conference Medical Physics · January 1, 2010 Purpose: The anisotropic analytical algorithm (AAA) has been shown to provide more accurate dose calculation due to 3D scatter and inhomogeneity corrections than the pencil beam convolution algorithm (PBC) for inhomogeneous anatomical regions such as lung ... Full text Cite

TH‐C‐204B‐07: Development of Image‐Guided Radiosurgery with Novalis TX for Small Animal Study

Conference Medical Physics · January 1, 2010 Purpose: Developing a protocol to accomplish small animal radiosurgery study conducted at our clinic in evaluating radiation‐induced erectile dysfunction. Method and Materials: Animals were sedated and scanned using commercial CT scanner. Scans were import ... Full text Cite

SU‐GG‐T‐362: Is Distance‐Dependent Energy Correction Needed for Dosimetric Measurements Surrounding Brachytherapy Sources?

Conference Medical Physics · January 1, 2010 Purpose: The answer depends on both the dosimeter's energy response and energy spectrum at distance (point of measurement) from the source. The latter is object of this study. Method and Materials: The spectra in water were calculated with Monte Carlo code ... Full text Cite

SU‐GG‐I‐14: A Method to Estimate Cone‐Beam CT Dose Index and Cone‐Beam Dose Length Product

Conference Medical Physics · January 1, 2010 Purpose: To characterize the cone‐beam CTDI (CBCTDI) and cone‐beam dose length product (CBDLP) by Monte Carlo (MC) technique. Method and Materials: An extended CT head phantom (60cm long) and an extended CT body phantom (90cm long) were created in our BEAM ... Full text Cite

SU‐GG‐I‐57: Dose and Image Quality Evaluation for Partial and Full‐Angle Kilovoltage Cone‐Beam CT Protocols

Conference Medical Physics · January 1, 2010 Purpose: To assess imaging dose of partial and full‐angle CBCT scan protocols, and to evaluate their image quality. Method and Materials: The CTDI of the six new CBCT protocols for Varian OBI were obtained by ion chamber (IC) measurements and Monte Carlo ( ... Full text Cite

SU‐EE‐A1‐03: Arc Modulated Radiation Therapy Based on Linear Models

Conference Medical Physics · January 1, 2010 Purpose: The challenge for implementing promising Arc Modulated Radiation Therapy (AMRT) is its effectiveness of treatment planning tools to find optimal multileaf collimator (MLC) sequence and the fluence map. This study provides a new approach to the abo ... Full text Cite

WE‐B‐BRA‐03: Adaptive Image‐Guided Radiation Therapy (AIGRT) for Hypo‐Fractionated Prostate Cancer Treatment

Conference Medical Physics · January 1, 2010 Purpose: The large fractional dose of hypo‐fractionated prostate treatment requires high accuracy of daily treatment delivery. This study analyzes the performance of an adaptive IGRT (AIGRT) technique, which combines image guidance and adaptive re‐planning ... Full text Cite

TU‐E‐BRB‐03: A Planning Quality Evaluation Tool for Adaptive IMRT Treatment Based on Machine Learning

Conference Medical Physics · January 1, 2010 Purpose: To monitor the quality of adaptive IMRT plans, especially dose sparing for the organs‐at‐risk (OARs), a plan evaluation tool is developed to predict the dose volume histogram (DVH) based on patient's anatomical information and a database of high q ... Full text Cite

SU‐GG‐J‐76: Validation of a Proposed Optimal Slow Gantry Rotation Technique for On‐Board Four‐Dimensional Imaging Using Lung Patient Data

Conference Medical Physics · January 1, 2010 Purpose: Substantial efforts have been made in recent years to develop on‐board four‐dimensional (4D) imaging techniques using gantry mounted cone‐beam imaging devices. This study validates a slow gantry rotation 4D imaging protocol using lung patient data ... Full text Cite

TH‐A‐BRA‐03: TG‐104: In‐Room kV Imaging for IGRT

Conference Medical Physics · January 1, 2010 In‐room kilovoltage (kV) x‐ray imaging refers to radiographic imaging using kV x‐ray sources in the radiation treatment room. It has been widely accepted for radiotherapy target localization and treatment intervention. Task Group 104 (TG 104) reports on th ... Full text Cite

SU‐DD‐A3‐03: How Accurately Can the Internal Target Volume (ITV) from a Free‐Breathing Cone Beam Computed Tomography (FB‐CBCT) Scan Be Used for Target Verification?

Conference Medical Physics · January 1, 2010 Purpose: An internal target volume (ITV) is often identified by acquiring a free‐breathing cone‐beam computed tomography scan (FB‐CBCT) to verify patient setup of tumors affected by respiratory motion. However, its accuracy is not well understood. The purp ... Full text Cite