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Ferdinand Kappes

Associate Professor of Biology at Duke Kunshan University
DKU Faculty

Scholarly Works - Preprints


Phosphorylation of serines 287/288 in DEK regulates cell-type-specific chromatin occupancy and compaction

Preprint · 2026 The conserved multifunctional chromatin modulator and oncogene DEK exhibits context-dependent genomic binding and function, but how these activities are regulated in cancer remains poorly understood. Using multi-omics and biochemical approaches, we find th ... Full text Cite

DEK-rRNA interactions regulate ribosome biogenesis and stress response

Preprint · 2024 DNA/chromatin-based functions of the DEK oncogene, a unique nucleic acid-interacting factor in metazoans, have been widely investigated, yet its role in cellular RNA biology is under-studied. Herein we employed CLIP-seq alongside mutational, biochemical, a ... Full text Cite