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Donald Fleenor

Research Scientist, Senior
Pharmacology & Cancer Biology
Box 3813 Med Ctr, Durham, NC 27710
LSRC, Room C351, Durham, NC 27710

Overview


My research focuses on the contributions of lactogenic and somatogenic signaling on fetal and perinatal growth. We have developed a novel double mutant mouse model that displays many of the features of the metabolic syndrome. The double mutant mice. which are growth hormone deficient and lactogen resistant, demonstrate growth failure, hypoinsulinemia, insulin hyper-sensitivity, and hypoglycemia at one week of age, but develop obesity, insulin resistance, and glucose intolerance by 6-9 months of age.


Prolactin, placental lactogen, growth hormone, STAT5, IGF-I, IGF-II, transcription factors, adipogenesis

Current Appointments & Affiliations


Education, Training & Certifications


Emory University · 1987 Ph.D.