John William Foreman

Journal article Pediatr Nephrol · February 2007 Featured Publication Acute interstitial nephritis (AIN) is a known cause of acute renal failure in children. In most instances, drug therapy is the offending agent. Although granuloma formation has been observed in drug-induced interstitial nephritis, it is not a commonly asso ... Full text Link to item Cite

Mutations in INVS encoding inversin cause nephronophthisis type 2, linking renal cystic disease to the function of primary cilia and left-right axis determination.

Journal article Nat Genet · August 2003 Featured Publication Nephronophthisis (NPHP), an autosomal recessive cystic kidney disease, leads to chronic renal failure in children. The genes mutated in NPHP1 and NPHP4 have been identified, and a gene locus associated with infantile nephronophthisis (NPHP2) was mapped. Th ... Full text Link to item Cite

Prevalence and clinical correlates of glomerulopathy in children with sickle cell disease.

Journal article J Pediatr · June 2000 Featured Publication OBJECTIVES: Glomerular disease and renal failure cause substantial morbidity for patients with sickle cell disease (SCD). Proteinuria is an early manifestation of sickle nephropathy, but the prevalence of proteinuria and its clinical correlations in childr ... Link to item Cite

Appearance of immune complex glomerulonephritis following the onset of type I diabetes mellitus in a child.

Journal article Am J Kidney Dis · November 1997 Featured Publication Renal disease is a frequent late complication of type I diabetes mellitus, occurring almost entirely in adult patients. Typical diabetic nephropathy is characterized by proteinuria, and by the histological lesions of mesangial expansion and basement membra ... Full text Link to item Cite