Scholars@Duke
Gayathri R. Devi

Gayathri R. Devi

Adjunct Professor in the Department of Surgery
Surgery, Surgical Sciences
Box 2606 Med Ctr, Durham, NC 27710
477 Med.Sci.Res.Bldg. (MSRB1), 2606 DUMC, Durham, NC 27710

Scholarly Works - Conferences

Abstract PO5-27-02: A Tumor Emboli Platform for Morphometric Analysis, Drug screening and for Intravital Optical Imaging in a Murine Model to Simulate Clinicopathological Features of Inflammatory Breast Cancer

Conference Cancer Research · May 2, 2024 AbstractBackground: Inflammatory breast cancer (IBC) is distinguished by the presence of tumor emboli, clusters of tumor cells, found within breast parenchyma and dermal lymphatic vessels. These emboli serve ... Full text Cite

Abstract PO5-10-04: Rare to Care: Assessing Awareness and Health Disparity Factors Related to Inflammatory Breast Cancer in the Primary Care Setting

Conference Cancer Research · May 2, 2024 AbstractBackground: The diagnosis of inflammatory breast cancer (IBC) is life-changing as it is a rare, highly aggressive breast cancer variant designated by NIH as a cancer health disparity. Given the uniqu ... Full text Cite

Abstract 6203: An altered profile of ribosomal proteins and ERK-eIF4E translational control in an inflammatory breast cancer model of acquired resistance and reversal is associated with pathological complete response in patients

Conference Cancer Research · March 22, 2024 AbstractBackground: Drug resistance is a major challenge in inflammatory breast cancer (IBC), a hyperproliferative subtype characterized by the presence of diffuse tumor cell clusters that show high level of ... Full text Cite

Comparison of novel tin coated and uncoated carbide tool in CNC dry turning of aisi H13 to maximize material removal rate

Conference Aip Conference Proceedings · November 14, 2023 To compare the material removal rate obtained during dry turning of AISI H13 tool steel using novel TiN coated and uncoated carbide tools. Materials and Methods:The work material chosen for the study is AISI H13 tool steel of dimension 25 mm diameter and 5 ... Full text Cite

Comparison of novel tin coated and uncoated carbide tool in CNC wet turning of EN31 to maximize material removal rate

Conference Aip Conference Proceedings · November 14, 2023 This research is about the comparison of novel TiN coated and uncoated carbide tools in CNC wet turning of EN31 to maximize material removal rate. Materials and methods: Work material used was EN31 tool steel and cutting tools used was novel TiN coated and ... Full text Cite

Abstract 4217: Cumulative environmental quality is associated with breast cancer incidence differentially by summary stage and urbanicity

Conference Cancer Research · April 4, 2023 AbstractIndividual environmental contaminants have been associated with breast cancer (BCa); however, simultaneous evaluations of multiple exposures are limited. The USEPA has constructed an environmental qu ... Full text Cite

Abstract P4-03-12: Cumulative Environmental Quality is Associated with Differential Breast Cancer Incidence by Summary Stage and Urbanicity

Conference Cancer Research · March 1, 2023 AbstractBackground: Individual environmental contaminants have been associated with breast cancer; however, evaluations of multiple exposures simultaneously are limited. The USPA has constructed an environme ... Full text Cite

Abstract P3-08-06: Monitoring Lymphovascular Invasion and Tumor Growth of Inflammatory Breast Cancer in a Murine Lymphatic Reporter Window Chamber Model

Conference Cancer Research · March 1, 2023 AbstractBackground: Lymphovascular invasion (LVI) is a major route of metastatic dissemination and recent studies indicate its value as an independent prognostic indicator for advanced breast, colorectal, sq ... Full text Cite

Abstract B045: Assessing knowledge and barriers at the primary care provider level that contribute to disparities in inflammatory breast cancer diagnosis and treatment

Conference Cancer Epidemiology, Biomarkers & Prevention · January 1, 2023 AbstractBackground: Although recognized as the most lethal breast cancer, inflammatory breast cancer (IBC), a NCI designated rare cancer and a cancer health disparity, is severely understudied. Given the uni ... Full text Cite

Automatic Paddy Drying Robot

Conference 2023 International Conference on System Computation Automation and Networking Icscan 2023 · January 1, 2023 The process of drying rice paddies holds immense significance in rice production, profoundly influencing thequality of the final yield by ensuring the ideal moisture content. Among the conventional techniques for managing the solar drying process, manual t ... Full text Cite

Speed and Distance Detection for Highway Traffic using Python

Conference 2023 International Conference on System Computation Automation and Networking Icscan 2023 · January 1, 2023 This Python -based scheme presents an innovative approach to bolstering road safety by harnessing the power of computer vision and machine learning. The primary objective is to provide drivers with crucial real-time information for informed lane change dec ... Full text Cite

Abstract P1-04-07: Xiap expression is associated with infiltration of cd163+ tumor-associated macrophages in the tumor micro-environment of inflammatory breast cancer

Conference Cancer Research · February 15, 2022 AbstractBACKGROUND: Inflammatory breast cancer (IBC) is a rare, but aggressive type of locally advanced breast cancer for which a specific immune response seems to be an important driver (Van Laere et al., C ... Full text Cite

Abstract 548: Birinapant enhances gemcitabine's anti-tumor efficacy in triple-negative breast cancer by inducing intrinsic pathway-dependent apoptosis

Conference Cancer Research · August 15, 2020 AbstractBackground: Apoptosis resistance is a hallmark of cancer, and apoptosis regulators have been targeted for cancer treatment. A class of such regulators is inhibitor of apoptosis proteins (IAPs), which ... Full text Cite

Abstract PR06: North Carolina environmental quality is associated with distant/metastatic breast cancer: Evidence for rural-urban disparities

Conference Cancer Prevention Research · July 1, 2020 AbstractBreast cancer is a complex and multifactorial disease, and there is increasing evidence of association between breast cancer incidence and environmental factors. This study sought to investigate the ... Full text Cite

Abstract B035: Identification of a tumor cell adaptive stress response signaling pathway, which drives aggressive breast cancer phenotype and therapeutic resistance, in African American patients with locally advanced breast cancer subtypes

Conference Cancer Epidemiology, Biomarkers & Prevention · June 1, 2020 AbstractIntroduction: The higher incidence of biologically aggressive and treatment-resistant breast cancer (BCa) subtypes, which includes triple negative (TN), basal, and inflammatory breast cancer (IBC), c ... Full text Cite

Abstract IA18: North Carolina Central University and Duke Cancer Institute's collaborative cancer research and education program: Connecting cancer disparities translational research, clinical trials operations, and community engagement

Conference Cancer Epidemiology, Biomarkers & Prevention · June 1, 2020 AbstractThree interrelated contributors to cancer disparities include the lack of diversity among investigators contributing to cancer research, the deficiency of minority participation in clinical trials an ... Full text Cite

Abstract B034: Improving patient-centered care for inflammatory breast cancer: Strategies for addressing barriers faced by patients, researchers, and providers

Conference Cancer Epidemiology, Biomarkers & Prevention · June 1, 2020 AbstractIntroduction: Inflammatory breast cancer (IBC) is a rare but the most lethal breast cancer often misdiagnosed as mastitis or dermatitis since majority of cases lack a clinically apparent tumor mass a ... Full text Cite

Abstract A038: Current unmet needs in inflammatory breast cancer/IBC patient care: Analysis of open-ended responses from a community engagement session of clinicians, researchers, advocates, and patients at the Duke Consortium for IBC conference

Conference Cancer Epidemiology, Biomarkers & Prevention · June 1, 2020 AbstractIntroduction: Inflammatory breast cancer (IBC) is an understudied and aggressive breast cancer subtype, accounting for 7-10% of all breast cancer-related deaths in the United States. IBC is more comm ... Full text Cite

Abstract D093: Who carries the excess cancer risk burden: Implications of disparities in polycyclic aromatic hydrocarbon exposure

Conference Cancer Epidemiology, Biomarkers & Prevention · June 1, 2020 AbstractPolycyclic aromatic hydrocarbons (PAHs) are a toxic and ubiquitous class of environmental chemicals sourced from industrial practices, tobacco smoke, grilled and smoked meats, car exhaust, and other ... Full text Cite

Abstract A023: Results from a town hall meeting: Inflammatory breast cancer listening session led by KOMEN scholars

Conference Cancer Epidemiology, Biomarkers & Prevention · June 1, 2020 AbstractIntroduction: Cancer is the leading cause of death in North Carolina. While the incidence rate of breast cancer (BC) is higher in White women, African American and Latino women are more likely to die ... Full text Cite

Abstract B122: Spatial analysis of ductal carcinoma in situ, locoregional, and distant metastatic breast cancer in North Carolina: Evidence for rural-urban disparities

Conference Cancer Epidemiology, Biomarkers & Prevention · June 1, 2020 AbstractIntroduction: A projected 8870 women will be diagnosed with breast cancer in North Carolina (NC) in 2019, with 1390 estimated deaths. However, breast cancer is a heterogenous disease, and investigati ... Full text Cite

Abstract C100: Identification and functional characterization of a novel GLI1 splice variant in breast cancer

Conference Cancer Epidemiology, Biomarkers & Prevention · June 1, 2020 AbstractThe purpose of this study is to investigate the biologic significance of novel GLI1 splice variants in breast cancer. African American (AA) women suffer a disproportionately high burden of basal-like ... Full text Cite

Abstract P1-03-03: Multichannel serial imaging of transgenic, preclinical murine models provides the first quantitative analysis of the unusual growth kinetics and lymph-vascular invasion of patient-derived inflammatory breast cancer cells and tumor emboli

Conference Cancer Research · February 15, 2020 AbstractBackground: Lymphovascular invasion (LVI), a critical feature of advanced cancers, is a major route of metastatic dissemination. Of the clinically-distinct types of breast cancer, the most lethal var ... Full text Cite

Removal of 2, 4 dichlorophenol from aqueous medium using chemically modified low-cost adsorbent: Kinetics, isotherm, thermodynamics and regeneration studies

Conference Desalination and Water Treatment · July 1, 2019 Elimination of 2,4 D from water bodies is very much essential and possible using adsorption. Using commercial adsorbents, removal of 2,4 D can be efficient but requires high operating cost and hence this study focuses on feasibility of producing Activated ... Full text Cite

Abstract B47: Efficacy of GLI antagonists in triple-negative inflammatory breast cancer 2D and 3D models

Conference Cancer Epidemiology, Biomarkers & Prevention · July 1, 2018 AbstractOur objective was to investigate the differential effects of specific GLI1 antagonists in triple-negative inflammatory breast cancer 2D and 3D cell culture systems. Inflammatory breast cancer (IBC) a ... Full text Cite

Abstract 4854: Targeting ribonucleotide reductase M2 using didox causes inhibition of estrogen receptor-negative, inflammatory breast cancer cell proliferation and tumor emboli formation in culture

Conference Cancer Research · July 1, 2018 AbstractRibonucleotide reductase (RR) catalyzes the conversion of ribonucleotides to deoxyribonucleotides during the rate-limiting step of DNA synthesis. Given its significant role in cell cycle regulation, ... Full text Cite

Abstract P3-16-02: Nanotheranostics using plasmonic gold nanostars to target inflammatory breast cancer cells and tumor emboli

Conference Cancer Research · February 15, 2017 AbstractIntroduction: Due to the aggressive nature of inflammatory breast cancer (IBC) and insensitive imaging techniques, patients diagnosed with IBC have a poor prognosis. IBC's unique ability to form embo ... Full text Cite

Abstract B44: Immune pathway dysregulations in inflammatory breast cancer health disparity

Conference Cancer Epidemiology, Biomarkers & Prevention · February 1, 2017 AbstractBackground: Inflammatory breast cancer (IBC) is a distinct, aggressive and the most lethal form of breast cancer. Furthermore, data from population-based registries, when stratified by race and compa ... Full text Cite

Abstract LB-015: XIAP induction by the MAPK-eIF4G1 pathway drives NFκB activation in inflammatory breast cancer growth and therapeutic resistance

Conference Cancer Research · July 15, 2016 AbstractInflammatory breast cancer (IBC) is the most lethal, distinct form of breast cancer, however, the basis for its aggressiveness and rapid acquisition of drug resistance is not fully understood. Using ... Full text Cite

Abstract P6-14-05: A novel link between anti-apoptotic signaling, NFκB, and SMAD7 in IBC pathobiology

Conference Cancer Research · May 1, 2015 AbstractBackground: Inflammatory breast cancer (IBC) has the highest lethality amongst all subtypes of breast cancer and develops rapid therapeutic resistance. High NFκB activation has been identified as a d ... Full text Cite

Abstract 951: Cross-resistance and re-sensitization to multiple drugs in an IBC model of lapatinib acquired resistance parallels redox adaptation.

Conference Cancer Research · April 15, 2013 AbstractInflammatory breast cancer (IBC) is characterized by rapid progression from onset of disease, therefore an early and aggressive multimodal therapy is essential to improve outcome. IBC tumors are freq ... Full text Cite

Gene Therapy of Cancer - 11th International Conference: 12-14 December 2002, San Diego, USA

Conference Idrugs · February 1, 2003 At this excellent meeting, preclinical, phase I and some phase II data were presented concerning significant advances with various viral and non-viral-based vectors. In addition, a few talks discussed genomic-based therapies such as those involving antisen ... Cite

Inhibition of tumor growth using an antisense morpholino oligomer to integrin alpha(v) subunit

Conference ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY · May 1, 2002 Link to item Cite