Glenn S. Edwards
Professor of Physics
Glenn Edwards investigates biological systems using a range of experimental techniques and theoretical methods from physics. His interests include Investigations of energy transduction where laser energy transforms into vibrational energy of biological molecules which then transforms into heat and pressure pulses that selectively drive tissue-scale dynamics. This line of research has led to human surgical applications of Free-Electron Lasers and spin-off laser technology. Another interest includes investigations of how biology harnesses physical mechanisms in biomechanical processes. This line of research investigates tissue dynamics and pattern formation during early development in Drosophila embryos.
Current Appointments & Affiliations
- Professor of Physics, Physics, Trinity College of Arts & Sciences 1999
Contact Information
- Box 90305, Durham, NC 27708-0305
- French Family Science Center, 2314, Durham, NC 27708
-
gedwards@phy.duke.edu
(919) 660-2674
- Background
-
Education, Training, & Certifications
- Ph.D., University of Maryland, College Park 1984
- B.S., University of Maryland, College Park 1978
-
Duke Appointment History
- Director, Physics, Trinity College of Arts & Sciences 1999 - 2008
- Recognition
-
Awards & Honors
- Research
-
Selected Grants
- Morphogenesis: Biophysics and Genetics of Dorsal Closure awarded by National Institutes of Health 1984 - 2018
- Complex Networks: Structure and Function of Large-Scale Neural Networks awarded by Army Research Office 2012 - 2015
- Structural Biology and Biophysics Training Program awarded by National Institutes of Health 1994 - 2015
- Complex Networks Response to Excitations awarded by Army Research Office 2007 - 2010
- Biomedical and Biological Research Applications of a Storage-Ring Free-Electron Laser awarded by Air Force Office of Scientific Research 2000 - 2008
- Mathematical Analysis of Non-Stationary Fluctuations awarded by Army Research Office 2003 - 2007
- Novel Research Opportunities Using the Duke Storage-Ring FEL awarded by Air Force Office of Scientific Research 2004 - 2006
- Center for FEL Research in the Medical, Biological, and Materials Sciences awarded by Air Force Office of Scientific Research 2000 - 2001
- Biophysical Research at the Duke FEL Laboratory awarded by Office of Naval Research 1999 - 2000
- Infrastructure Support for Light Sources at the Duke FEL Laboratory awarded by Office of Naval Research 1994 - 2000
- Duke Free Electron Laser Program Plan-FY99 awarded by Office of Naval Research 1994 - 2000
- Publications & Artistic Works
-
Selected Publications
-
Academic Articles
-
Lo, Wei-Chang, Craig Madrak, Daniel P. Kiehart, and Glenn S. Edwards. “Unified biophysical mechanism for cell-shape oscillations and cell ingression.” Physical Review. E 97, no. 6–1 (June 2018): 062414. https://doi.org/10.1103/physreve.97.062414.Full Text
-
Kiehart, Daniel P., Janice M. Crawford, Andreas Aristotelous, Stephanos Venakides, and Glenn S. Edwards. “Cell Sheet Morphogenesis: Dorsal Closure in Drosophila melanogaster as a Model System.” Annual Review of Cell and Developmental Biology 33 (October 2017): 169–202. https://doi.org/10.1146/annurev-cellbio-111315-125357.Full Text
-
Lu, Heng, Adam Sokolow, Daniel P. Kiehart, and Glenn S. Edwards. “Quantifying dorsal closure in three dimensions.” Molecular Biology of the Cell 27, no. 25 (December 2016): 3948–55. https://doi.org/10.1091/mbc.e16-06-0400.Full Text
-
Lu, Heng, Adam Sokolow, Daniel P. Kiehart, and Glenn S. Edwards. “Remodeling Tissue Interfaces and the Thermodynamics of Zipping during Dorsal Closure in Drosophila.” Biophysical Journal 109, no. 11 (December 2015): 2406–17. https://doi.org/10.1016/j.bpj.2015.10.017.Full Text
-
Wells, Adrienne R., Roger S. Zou, U Serdar Tulu, Adam C. Sokolow, Janice M. Crawford, Glenn S. Edwards, and Daniel P. Kiehart. “Complete canthi removal reveals that forces from the amnioserosa alone are sufficient to drive dorsal closure in Drosophila.” Molecular Biology of the Cell 25, no. 22 (November 2014): 3552–68. https://doi.org/10.1091/mbc.e14-07-1190.Full Text
-
Sokolow, Adam, Yusuke Toyama, Daniel P. Kiehart, and Glenn S. Edwards. “Cell ingression and apical shape oscillations during dorsal closure in Drosophila.” Biophysical Journal 102, no. 5 (March 6, 2012): 969–79. https://doi.org/10.1016/j.bpj.2012.01.027.Full Text
-
Layton, Anita T., Yusuke Toyama, Guo-Qiang Yang, Glenn S. Edwards, Daniel P. Kiehart, and Stephanos Venakides. “Drosophila morphogenesis: tissue force laws and the modeling of dorsal closure.” Hfsp Journal 3, no. 6 (December 15, 2009): 441–60. https://doi.org/10.2976/1.3266062.Full Text
-
Edwards, G. S. “Mechanisms for soft-tissue ablation and the development of alternative medical lasers based on investigations with mid-infrared free-electron lasers.” Laser and Photonics Reviews 3, no. 6 (November 5, 2009): 545–55. https://doi.org/10.1002/lpor.200810063.Full Text
-
Wagner, W., A. Sokolow, R. Pearlstein, and G. Edwards. “Thermal vapor bubble and pressure dynamics during infrared laser ablation of tissue.” Applied Physics Letters 94, no. 1 (January 19, 2009). https://doi.org/10.1063/1.3063127.Full Text
-
Bush, William D., Jacob Garguilo, Fabio A. Zucca, Chiara Bellei, Robert J. Nemanich, Glenn S. Edwards, Luigi Zecca, and John D. Simon. “Neuromelanins isolated from different regions of the human brain exhibit a common surface photoionization threshold.” Photochemistry and Photobiology 85, no. 1 (January 2009): 387–90. https://doi.org/10.1111/j.1751-1097.2008.00476.x.Full Text
-
Layton, Anita T., Yusuke Toyama, Guo-Qiang Yang, Glenn S. Edwards, Daniel P. Kiehart, and Stephanos Venakides. “Drosophila Morphogenesis: Tissue Force Laws and the Modeling of Dorsal Closure.” Human Frontier Science Program Journal 3, no. 6 (2009).
-
Wagner, Wolfgang, Adam Sokolow, Robert Pearlstein, and Glenn Edwards. “Thermal Vapor Bubble and Pressure Dynamics During Infrared Laser Ablation of Tissue.” Applied Physics Letters 94, no. 013901 (2009).
-
Toyama, Yusuke, Xomalin G. Peralta, Adrienne R. Wells, Daniel P. Kiehart, and Glenn S. Edwards. “Apoptotic force and tissue dynamics during Drosophila embryogenesis.” Science (New York, N.Y.) 321, no. 5896 (September 2008): 1683–86. https://doi.org/10.1126/science.1157052.Full Text
-
Rodriguez-Diaz, Alice, Yusuke Toyama, Daniel L. Abravanel, John M. Wiemann, Adrienne R. Wells, U Serdar Tulu, Glenn S. Edwards, and Daniel P. Kiehart. “Actomyosin purse strings: renewable resources that make morphogenesis robust and resilient.” Hfsp Journal 2, no. 4 (August 2008): 220–37. https://doi.org/10.2976/1.2955565.Full Text
-
Edwards, G., W. Wagner, A. Sokolow, and R. Pearlstein. “Pressure (mechanical) effects in infrared tissue ablation.” Progress in Biomedical Optics and Imaging Proceedings of Spie 6854 (April 21, 2008). https://doi.org/10.1117/12.776999.Full Text
-
Peralta, X. G., Y. Toyama, D. P. Kiehart, and G. S. Edwards. “Emergent properties during dorsal closure in Drosophila morphogenesis.” Physical Biology 5, no. 1 (April 10, 2008): 015004. https://doi.org/10.1088/1478-3975/5/1/015004.Full Text
-
Edwards, G. S., R. D. Pearlstein, M. L. Copeland, M. S. Hutson, K. Latone, A. Spiro, and G. Pasmanik. “6450 nm wavelength tissue ablation using a nanosecond laser based on difference frequency mixing and stimulated Raman scattering.” Opt Lett 32, no. 11 (June 1, 2007): 1426–28. https://doi.org/10.1364/ol.32.001426.Full Text Link to Item
-
Garguilo, Jacob, Lian Hong, Glenn S. Edwards, Robert J. Nemanich, and John D. Simon. “The surface oxidation potential of melanosomes measured by free electron laser-photoelectron emission microscopy.” Photochemistry and Photobiology 83, no. 3 (May 2007): 692–97. https://doi.org/10.1562/2006-09-11-ra-1037.Full Text
-
Peralta, X. G., Y. Toyama, M. S. Hutson, R. Montague, S. Venakides, D. P. Kiehart, and G. S. Edwards. “Upregulation of forces and morphogenic asymmetries in dorsal closure during Drosophila development.” Biophysical Journal 92, no. 7 (April 2007): 2583–96. https://doi.org/10.1529/biophysj.106.094110.Full Text
-
Kiehart, D. P., Y. Tokutake, M. S. Chang, M. S. Hutson, J. Wiemann, X. G. Peralta, Y. Toyama, A. R. Wells, A. Rodriguez, and G. S. Edwards. “Ultraviolet Laser Microbeam for Dissection of Drosophila Embryos” 3 (December 1, 2006): 87–103. https://doi.org/10.1016/B978-012164730-8/50137-4.Full Text
-
Kim, Y., J. Gustavsson, P. Wang, G. Swift, M. Emamian, S. Hartman, P. Wallace, and G. Edwards. “Commissioning of S-band RF gun and linac for the mark-III FEL facility at Duke University.” 28th International Free Electron Laser Conference, Fel 2006, December 1, 2006, 411–14.
-
Kim, Y., J. Gustavsson, P. Wang, G. Swift, M. Emamian, S. Hartman, P. Wallace, and G. Edwards. “The mark-III FEL facility at duke university.” 23rd International Linear Accelerator Conference, Linac 2006 Proceedings, December 1, 2006, 394–96.
-
Hong, Lian, Jacob Garguilo, Laura Anzaldi, Glenn S. Edwards, Robert J. Nemanich, and John D. Simon. “Age-dependent photoionization thresholds of melanosomes and lipofuscin isolated from human retinal pigment epithelium cells.” Photochemistry and Photobiology 82, no. 6 (November 2006): 1475–81. https://doi.org/10.1562/2006-03-14-ra-846.Full Text
-
Bush, William D., Jacob Garguilo, Fabio A. Zucca, Alberto Albertini, Luigi Zecca, Glenn S. Edwards, Robert J. Nemanich, and John D. Simon. “The surface oxidation potential of human neuromelanin reveals a spherical architecture with a pheomelanin core and a eumelanin surface.” Proceedings of the National Academy of Sciences of the United States of America 103, no. 40 (October 2006): 14785–89. https://doi.org/10.1073/pnas.0604010103.Full Text
-
Ye, Tong, Lian Hong, Jacob Garguilo, Anna Pawlak, Glenn S. Edwards, Robert J. Nemanich, Tadeusz Sarna, and John D. Simon. “Photoionization thresholds of melanins obtained from free electron laser-photoelectron emission microscopy, femtosecond transient absorption spectroscopy and electron paramagnetic resonance measurements of oxygen photoconsumption.” Photochemistry and Photobiology 82, no. 3 (May 2006): 733–37. https://doi.org/10.1562/2006-01-02-ra-762.Full Text
-
Edwards, G. S. “Applications of free-electron lasers to the biological and physical sciences.” Proceedings of Spie the International Society for Optical Engineering 5725 (July 21, 2005): 210–19. https://doi.org/10.1117/12.598150.Full Text
-
Edwards, G. S., S. J. Allen, R. F. Haglund, R. J. Nemanich, B. Redlich, J. D. Simon, and W. C. Yang. “Applications of free-electron lasers in the biological and material sciences.” Photochemistry and Photobiology 81, no. 4 (July 2005): 711–35. https://doi.org/10.1562/2004-11-08-ir-363.Full Text
-
Samokhvalov, Alexander, Lian Hong, Yan Liu, Jacob Garguilo, Robert J. Nemanich, Glenn S. Edwards, and John D. Simon. “Oxidation potentials of human eumelanosomes and pheomelanosomes.” Photochemistry and Photobiology 81, no. 1 (January 2005): 145–48. https://doi.org/10.1562/2004-07-23-rc-245.Full Text
-
Samokhvalov, A., J. Garguilo, W. C. Yang, G. S. Edwards, R. J. Nemanich, and J. D. Simon. “Photoionization threshold of eumelanosomes determined using UV free electron laser - Photoelectron emission microscopy.” Journal of Physical Chemistry B 108, no. 42 (October 21, 2004): 16334–38. https://doi.org/10.1021/jp046701q.Full Text
-
Sobol, E., A. Sviridov, M. Kitai, V. Bagratashvili, J. Gilligan, and G. Edwards. “Laser-induced alterations of the Infrared light absorption by biological tissues: Radiometric and spectroscopic measurements.” Proceedings of Spie the International Society for Optical Engineering 4829 II (December 1, 2003): 1030–31. https://doi.org/10.1117/12.530961.Full Text
-
Edwards, Glenn S., and M Shane Hutson. “Advantage of the Mark-III FEL for biophysical research and biomedical applications.” Journal of Synchrotron Radiation 10, no. Pt 5 (September 2003): 354–57. https://doi.org/10.1107/s0909049503007970.Full Text
-
Edwards, G. S., R. H. Austin, F. E. Carroll, M. L. Copeland, M. E. Couprie, W. E. Gabella, R. F. Huglund, et al. “Free-electron-laser-based biophysical and biomedical instrumentation.” Review of Scientific Instruments 74, no. 7 (July 1, 2003): 3207–45. https://doi.org/10.1063/1.1584078.Full Text
-
Sobol, Emil N., Alexander P. Sviridov, Moishe S. Kitai, and Glenn S. Edwards. “Temperature alterations of infrared light absorption by cartilage and cornea under free-electron laser radiation.” Applied Optics 42, no. 13 (May 2003): 2443–49. https://doi.org/10.1364/ao.42.002443.Full Text
-
Hutson, M Shane, Yoichiro Tokutake, Ming-Shien Chang, James W. Bloor, Stephanos Venakides, Daniel P. Kiehart, and Glenn S. Edwards. “Forces for morphogenesis investigated with laser microsurgery and quantitative modeling.” Science (New York, N.Y.) 300, no. 5616 (April 2003): 145–49. https://doi.org/10.1126/science.1079552.Full Text
-
Sobol, Emil, Alexander Sviridov, Moishe Kitai, Jonathan M. Gilligan, Norman H. Tolk, and Glenn S. Edwards. “Time-resolved, light scattering measurements of cartilage and cornea denaturation due to free electron laser radiation.” Journal of Biomedical Optics 8, no. 2 (April 2003): 216–22. https://doi.org/10.1117/1.1559996.Full Text
-
Edwards, G. S., R. H. Austin, F. E. Carroll, M. L. Copeland, M. E. Couprie, W. E. Gabella, R. F. Haglund, et al. “FEL-based biophysical and biomedical instrumentation.” Invited Paper, Review of Scientific Instruments 74, no. 7 (2003): 3207–45.
-
Sobol, E., A. Sviridov, M. Kitai, J. Gilligan, N. Tolk, and G. Edwards. “Time-resolved, light scattering measurements of cartilage and cornea denaturation due to FEL radiation: effect of infrared wavelength.” Journal of Biomedical Optics 8 (2003): 216–22.
-
Hutson, M Shane, Susanne A. Hauger, and Glenn Edwards. “Thermal diffusion and chemical kinetics in laminar biomaterial due to heating by a free-electron laser.” Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics 65, no. 6 Pt 1 (June 17, 2002): 061906. https://doi.org/10.1103/physreve.65.061906.Full Text
-
Hutson, M. S., R. A. Palmer, M. S. Chang, A. Gillikin, V. Litvinenko, and G. Edwards. “Commissioning of a UV/time-resolved-FTIR beamline at the Duke FEL laboratory.” Nuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment 483, no. 1–2 (May 1, 2002): 560–64. https://doi.org/10.1016/S0168-9002(02)00382-0.Full Text
-
Edwards, G. S., J. Neev, A. Ostendorf, and J. C. Sutherland. “Erratum: (Commercial and Biomedical Applications of Ultrafast and Free-Electron Lasers (23-24 January 2002)).” Proceedings of Spie the International Society for Optical Engineering 4633 (January 1, 2002): 243–44.
-
Edwards, G. S., M. Shane Hutson, and S. Hauger. “Heat diffusion and chemical kinetics in Mark-III FEL tissue ablation.” Proceedings of Spie the International Society for Optical Engineering 4633 (January 1, 2002): 184–93. https://doi.org/10.1117/12.461378.Full Text
-
Edwards, G., M. Shane Hutson, S. Hauger, J. Kozub, J. Shen, C. Shieh, K. Topadze, and K. Joos. “Comparison of OPA and Mark-III FEL for tissue ablation at 6.45 microns.” Proceedings of Spie the International Society for Optical Engineering 4633 (January 1, 2002): 194–200. https://doi.org/10.1117/12.461379.Full Text
-
Hutson, M. S., R. A. Palmer, A. Gillikin, M. S. Chang, V. N. Litvinenko, and G. S. Edwards. “UV/time-resolved FTIR beamline at the Duke FEL Laboratory.” Proceedings of Spie the International Society for Optical Engineering 4633 (January 1, 2002): 225–32. https://doi.org/10.1117/12.461383.Full Text
-
Pinayev, I., M. Emamian, J. Gustavsson, V. N. Litvinenko, P. Morcombe, O. Oakeley, V. Rathbone, G. Swift, P. Wang, and G. Edwards. “Status of Mark III FEL.” Proceedings of the Ieee Particle Accelerator Conference 4 (December 1, 2001): 2725–26.
-
Wang, P., V. Litvinenko, M. Emamian, J. Faircloth, J. Gustavsson, S. Hartman, S. Mikhailov, et al. “Status report on the Duke FEL facility.” Proceedings of the Ieee Particle Accelerator Conference 4 (December 1, 2001): 2819–20.
-
Swift, E. J., G. S. Edwards, J. Perdigão, J. Y. Thompson, M. F. Nunes, D. E. Ruddell, and A. Negishi. “Free-electron laser etching of dental enamel.” Journal of Dentistry 29, no. 5 (July 2001): 347–53. https://doi.org/10.1016/s0300-5712(01)00019-7.Full Text
-
Shen, J. H., J. A. Harrington, G. S. Edwards, and K. M. Joos. “Hollow-glass waveguide delivery of an infrared free-electron laser for microsurgical applications.” Applied Optics 40, no. 4 (February 2001): 583–87. https://doi.org/10.1364/ao.40.000583.Full Text
-
Edwards, G., C. Fowler, S. Hutson, V. Litvinenko, R. Palmer, and B. Roberts. “Light source capabilities and applications research at the Duke FEL laboratory.” Proceedings of Spie the International Society for Optical Engineering 3925 (January 1, 2000): 106–16.
-
Sobol, E., A. Sviridov, M. Kitai, J. Gilligan, and G. Edwards. “Alterations of absorption coefficients of tissue water as a result of the heating under the IR FEL radiation with different wavelengths.” Proceedings of Spie the International Society for Optical Engineering 3925 (January 1, 2000): 78–88.
-
Palmer, R. A., G. D. Smith, V. N. Litvinenko, and G. Edwards. “Fourier transform infrared picosecond time-resolved spectroscopy with a UV free electron laser pump and synchrotron IR probe.” Proceedings of Spie the International Society for Optical Engineering 3775 (December 1, 1999): 137–44.
-
Keay, B., M. Mendenhall, and G. Edwards. “Time-resolved infrared transmittance and reflectance of a propagating melt in gaas.” Physical Review B Condensed Matter and Materials Physics 60, no. 15 (January 1, 1999): 10898–902. https://doi.org/10.1103/PhysRevB.60.10898.Full Text
-
Sobol, E., A. Sviridov, M. Kitai, J. Gilligan, N. H. Tolk, and G. Edwards. “Effect of wavelength on threshold and kinetics of tissue denaturation under laser radiation.” Proceedings of Spie the International Society for Optical Engineering 3601 (January 1, 1999): 122–29. https://doi.org/10.1117/12.349995.Full Text
-
Shen, J. H., K. M. Joos, J. A. Harrington, D. M. O’Day, and G. S. Edwards. “Hollow waveguide delivered infrared free electron laser for microsurgical applications.” Proceedings of Spie the International Society for Optical Engineering 3262 (December 1, 1998): 130–34. https://doi.org/10.1117/12.309466.Full Text
-
Edwards, G., D. Engh, J. Kozub, and R. Williams. “Infrared dynamics of collagen, microtubules, and water: Biophysical research enabling biomedical FEL applications.” Nuclear Instruments and Methods in Physics Research, Section B: Beam Interactions With Materials and Atoms 144, no. 1–4 (September 2, 1998): 260–64. https://doi.org/10.1016/S0168-583X(98)00313-9.Full Text
-
Edwards, G. “10. Physical Mechanisms Governing the Ablation of Biological Tissue.” Experimental Methods in the Physical Sciences 30, no. C (December 1, 1997): 449–73. https://doi.org/10.1016/S0076-695X(08)60402-0.Full Text
-
Robinson, R. D., J. H. Shen, K. M. Joos, D. J. Shetlar, G. S. Edwards, and D. M. O’Day. “Healing of cultured human cornea after free electron laser ablation.” Investigative Ophthalmology and Visual Science 38, no. 4 (December 1, 1997).
-
Shen, J. H., K. J. Joos, D. J. Shetlar, R. D. Robinson, D. M. O’Day, and G. S. Edwards. “Investigation of a clinical intraocular microsurgical device using the infrared free electron laser.” Investigative Ophthalmology and Visual Science 38, no. 4 (December 1, 1997).
-
Shen, J. H., K. M. Joos, D. J. Shetlar, R. D. Robinson, G. K. Thind, G. S. Edwards, and D. M. O’Day. “Cultured human cornea healing process after free electron laser ablation.” Proceedings of Spie the International Society for Optical Engineering 2971 (December 1, 1997): 83–88. https://doi.org/10.1117/12.275106.Full Text
-
Wagner, K., E. Keyes, T. W. Kephart, and G. Edwards. “Analytical Debye-Huckel model for electrostatic potentials around dissolved DNA.” Biophysical Journal 73, no. 1 (July 1997): 21–30. https://doi.org/10.1016/s0006-3495(97)78043-3.Full Text
-
Hochberg, D., G. Edwards, and T. W. Kephart. “Representing structural information of helical charge distributions in cylindrical coordinates.” Physical Review E Statistical Physics, Plasmas, Fluids, and Related Interdisciplinary Topics 55, no. 3 (January 1, 1997): 3765–68. https://doi.org/10.1103/PhysRevE.55.3765.Full Text
-
Robinson, R. D., J. H. Shen, K. M. Joos, D. J. Shetlar, G. S. Edwards, and D. M. O’Day. “Healing of cultured human cornea after free electron laser ablation.” Investigative Ophthalmology and Visual Science 38, no. 4 (1997).
-
Shen, J. H., K. J. Joos, D. J. Shetlar, R. D. Robinson, D. M. O’Day, and G. S. Edwards. “Investigation of a clinical intraocular microsurgical device using the infrared free electron laser.” Investigative Ophthalmology and Visual Science 38, no. 4 (1997).
-
Shen, J. H., K. J. Joos, D. M. O’Day, and G. S. Edwards. “Investigation of clinical internal microsurgical device with use of hollow waveguide delivered infrared free electron laser.” Conference Proceedings Lasers and Electro Optics Society Annual Meeting Leos 11 (January 1, 1997): 151–52.
-
Tribble, J., D. C. Lamb, L. Reinisch, and G. Edwards. “Dynamics of gelatin ablation due to free-electron-laser irradiation.” Physical Review E Statistical Physics, Plasmas, Fluids, and Related Interdisciplinary Topics 55, no. 6 (January 1, 1997): 7385–89. https://doi.org/10.1103/PhysRevE.55.7385.Full Text
-
Edwards, G. S., D. Evertson, W. Gabella, R. Grant, T. L. King, J. Kozub, M. Mendenhall, et al. “Free-electron lasers: Reliability, performance, and beam delivery.” Ieee Journal on Selected Topics in Quantum Electronics 2, no. 4 (December 1, 1996): 810–16. https://doi.org/10.1109/2944.577303.Full Text
-
Joos, K. M., J. H. Shen, G. S. Edwards, D. J. Shetlar, J. M. Khoury, and R. D. Robinson. “Infrared free electron laser-tissue interactions with human ocular tissues.” Investigative Ophthalmology and Visual Science 37, no. 3 (February 15, 1996).
-
Joos, K. M., J. H. Shen, G. S. Edwards, D. J. Shetlar, J. M. Khoury, and R. D. Robinson. “Infrared free electron laser-tissue interactions with human.” Investigative Ophthalmology \& Visual Science 37, no. 3 (February 1996): 1985–1985.
-
Harris, D. M., L. Reinisch, G. S. Edwards, M. J. Yessik, S. Ashrafi, and J. Santos-Sacchi. “Midinfrared ablation of dentin with the Vanderbilt FEL.” Proceedings of Spie the International Society for Optical Engineering 2672 (January 1, 1996): 165–75. https://doi.org/10.1117/12.238765.Full Text
-
Joos, K. M. M. D., G. S. Edwards, J. H. Shen, D. Shetlar, R. Robinson, and D. M. D. O’Day. “Free Electron Laser (FEL) laser-tissue interaction with human cornea and optic nerve.” Proceedings of Spie the International Society for Optical Engineering 2673 (January 1, 1996): 89–92.
-
Johnson, J. B., K. Becker, and G. Edwards. “Pressure corrections for CoCl2 as a thermometer in an analytic ultracentrifuge.” Analytical Biochemistry 227, no. 2 (May 1995): 385–87. https://doi.org/10.1006/abio.1995.1295.Full Text
-
Zhang, M. Z., G. S. Edwards, L. Reinisch, V. A. Vasagrande, and J. A. Mckanna. “Microglial responses to free-electron laser incisions in rat-brain.” Faseb Journal 9, no. 3 (March 1995): A382–A382.
-
Edwards, G. S. “Biomedical and potential clinical applications for pulsed lasers operating near 6.45 um.” Optical Engineering 34, no. 5 (January 1, 1995): 1524–25. https://doi.org/10.1117/12.201620.Full Text
-
Becker, K., J. B. Johnson, and G. Edwards. “Broadband Pockels cell and driver for a Mark III-type free electron laser.” Review of Scientific Instruments 65, no. 5 (December 1, 1994): 1496–1501. https://doi.org/10.1063/1.1144881.Full Text
-
Johnson, J. B., G. Edwards, and M. Mendenhall. “Low-cost, high-performance array detector for spectroscopy based on a charge-coupled photodiode.” Review of Scientific Instruments 65, no. 5 (December 1, 1994): 1782–83. https://doi.org/10.1063/1.1144826.Full Text
-
Edwards, G., R. Logan, M. Copeland, L. Reinisch, J. Davidson, B. Johnson, R. Maciunas, M. Mendenhall, R. Ossoff, and J. Tribble. “Tissue ablation by a free-electron laser tuned to the amide II band.” Nature 371, no. 6496 (September 1994): 416–19. https://doi.org/10.1038/371416a0.Full Text
-
Edwards, G., D. Hochberg, and T. W. Kephart. “Structure in the electric potential emanating from DNA.” Physical Review E 50, no. 2 (January 1, 1994). https://doi.org/10.1103/PhysRevE.50.R698.Full Text
-
Hochberg, D., T. W. Kephart, and G. Edwards. “Structural information in the local electric field of dissolved B-DNA.” Physical Review E 49, no. 1 (January 1, 1994): 851–67. https://doi.org/10.1103/PhysRevE.49.851.Full Text
-
Henderson, D. O., R. Mu, E. Silberman, J. B. Johnson, and G. S. Edwards. “FEL investigations of energy transfer in condensed phase systems.” Proceedings of Spie the International Society for Optical Engineering 1854 (December 1, 1993): 105–16.
-
Edwards, G. S., B. Johnson, J. Kozub, J. Tribble, and K. Wagner. “Biomedical applications of free-electron lasers.” Optical Engineering 32, no. 2 (February 1993): 314–19.
-
Edwards, G., G. Ying, and J. Tribble. “Role of counterions in the gigahertz relaxation of wet DNA.” Physical Review A 45, no. 12 (January 1, 1992). https://doi.org/10.1103/PhysRevA.45.R8344.Full Text
-
Tribble, J., J. Kozub, A. Aly, R. Ossoff, and G. Edwards. “Role of immersion refractometry for investigating laser-induced effects in cells.” Lasers in Surgery and Medicine 12, no. 4 (January 1992): 459–63. https://doi.org/10.1002/lsm.1900120416.Full Text
-
Tolk, N. H., C. A. Brau, G. S. Edwards, G. Margaritondo, and J. T. McKinley. “The vanderbilt free-electron laser center for biomedical and materials research.” Proceedings of Spie the International Society for Optical Engineering 1552 (December 1, 1991): 7–13. https://doi.org/10.1117/12.50587.Full Text
-
Edwards, G., and C. Liu. “Sequence dependence of low-frequency Raman-active modes in nucleic acids.” Physical Review A 44, no. 4 (January 1, 1991): 2709–17. https://doi.org/10.1103/PhysRevA.44.2709.Full Text
-
Young, L., V. V. Prabhu, E. W. Prohofsky, and G. S. Edwards. “Prediction of modes with dominant base roll and propeller twist in B-DNA poly(dA)-poly(dT).” Physical Review A 41, no. 12 (January 1, 1990): 7020–23. https://doi.org/10.1103/PhysRevA.41.7020.Full Text
-
Liu, C., G. S. Edwards, S. Morgan, and E. Silberman. “Low-frequency, Raman-active vibrational modes of poly(dA)poly(dT).” Physical Review A 40, no. 12 (January 1, 1989): 7394–97. https://doi.org/10.1103/PhysRevA.40.7394.Full Text
-
Edwards, G. S., and N. H. Tolk. “Vanderbilt University FEL center for biomedical and materials research.” Nuclear Inst. and Methods in Physics Research, A 272, no. 1–2 (January 1, 1988): 37–39. https://doi.org/10.1016/0168-9002(88)90191-X.Full Text
-
Powell, J. W., G. S. Edwards, L. Genzel, F. Kremer, A. Wittlin, W. Kubasek, and W. Peticolas. “Investigation of far-infrared vibrational modes in polynucleotides.” Physical Review A 35, no. 9 (January 1, 1987): 3929–39. https://doi.org/10.1103/PhysRevA.35.3929.Full Text
-
Edwards, G. S., L. Genzel, W. L. Peticolas, and A. Rupprecht. “Measurements of a large anisotropy in the swelling of oriented DNA films in aqueous solution.” Biopolymers 25, no. 2 (February 1986): 223–27. https://doi.org/10.1002/bip.360250203.Full Text
-
Davis, C. C., G. S. Edwards, M. L. Swicord, J. Sagripanti, and J. Saffer. “Direct excitation of internal modes of DNA by microwaves.” Bioelectrochemistry and Bioenergetics 16, no. 1 (January 1, 1986): 63–76. https://doi.org/10.1016/0302-4598(86)80046-0.Full Text
-
Swicord, M. L., C. C. Davis, G. S. Edwards, and J. D. Saffer. “MICROWAVE-FIELD DRIVEN ACOUSTIC MODES OF DNA.” Bioengineering, Proceedings of the Northeast Conference, December 1, 1985, 226–29.
-
Edwards, G. S., C. C. Davis, J. D. Saffer, and M. L. Swicord. “Microwave-field-driven acoustic modes in DNA.” Biophysical Journal 47, no. 6 (June 1985): 799–807. https://doi.org/10.1016/s0006-3495(85)83984-9.Full Text
-
Edwards, G. S., C. C. Davis, J. D. Saffer, and M. L. Swicord. “Erratum: Resonant microwave absorption of selected DNA molecules (Physical Review Letters (1984) 53, 21 (2060)).” Physical Review Letters 53, no. 21 (December 1, 1984): 2060. https://doi.org/10.1103/PhysRevLett.53.2060.5.Full Text
-
Edwards, G. S. “Correction.” Physical Review Letters 53, no. 21 (1984): 2060–2060.
-
Edwards, G. S., C. C. Davis, J. D. Saffer, and M. L. Swicord. “Resonant microwave absorption of selected DNA molecules.” Physical Review Letters 53, no. 13 (January 1, 1984): 1284–87. https://doi.org/10.1103/PhysRevLett.53.1284.Full Text
-
Swicord, M. L., G. S. Edwards, J. L. Sagripanti, and C. C. Davis. “Chain-length-dependent microwave absorption of DNA.” Biopolymers 22, no. 12 (December 1983): 2513–16. https://doi.org/10.1002/bip.360221205.Full Text
-
-
Conference Papers
-
Edwards, G., J. Tribble, and J. Bruce Johnson. “Partitioning-of-energy model for laser ablation of tissue.” In Proceedings of Spie the International Society for Optical Engineering, 2134:134–43, 1994. https://doi.org/10.1117/12.182929.Full Text
-
Edwards, G., R. Logan, M. Copeland, L. Reinisch, J. Davidson, B. Johnson, R. MacIunas, et al. “Two years of free-electron laser applications research in biological physics.” In Proceedings of Spie the International Society for Optical Engineering, 2138:35–40, 1994. https://doi.org/10.1117/12.181340.Full Text
-
Mu, R., D. O. Henderson, J. B. Johnson, and G. S. Edwards. “Pulsed JR-FEL applications for the characterization of infrared optical materials.” In Proceedings of Spie the International Society for Optical Engineering, 2138:97–106, 1994. https://doi.org/10.1117/12.181347.Full Text
-
Edwards, G., B. Johnson, J. Kozub, J. Tribble, and K. Wagner. “Applications of free-electron lasers to measurements of energy transfer in biopolymers and materials.” In Proceedings of Spie the International Society for Optical Engineering, 1646:13–23, 1992. https://doi.org/10.1117/12.137462.Full Text
-
-
- Teaching & Mentoring
-
Recent Courses
- Scholarly, Clinical, & Service Activities
-
Presentations & Appearances
- Biomechanical mechanism for the inward force that drives ventral furrow formation: basal-to-apical myosin repolarization triggers Euler buckling of tissue within a central band of the presumptive mesoderm. October 1, 2013 2013
- Biophysics research and its application to the life sciences. December 16, 2012 2012
- Dorsal closure in three-dimensions: turgor pressure and zipping. December 16, 2012 2012
- Molecular force production, cell-shape changes, and tissue patterning during Drosophila development. December 16, 2012 2012
- Consequences of ‘Life at low Reynolds number’ for the biophysical investigation of polymer dynamics and tissue patterning in developmental biology. October 1, 2011 2011
- Dynamics of dorsal closure during Drosophila morphogenesis. August 1, 2011 2011
- The Golden Hour (plus some). August 1, 2011 2011
- Tissue ablation with pulsed, infrared lasers: protein and water dynamics underlying surgical applications. July 1, 2011 2011
- Potential biological applications of THz/IR. April 1, 2011 2011
- Biophysical investigations of tissue dynamics during early development in Drosophila. March 1, 2011 2011
- Dynamics of early morphogenesis in Drosophila embryos,. December 17, 2010 2010
- Early embryonic patterning in Drosophila. December 17, 2010 2010
- Tissue ablation with pulsed, infrared lasers: protein and water dynamics underlying the human surgical applications. December 17, 2010 2010
- Tissue biomechanics: biophysical investigations of patterned development and mechano-transduction in developmental biology. December 17, 2010 2010
- Tissue dynamics: open research questions. December 17, 2010 2010
- Tissue mechanics: biophysical investigation of Drosophila morphogenesis. December 17, 2010 2010
- Regulation of the biomechanical dynamics of tissue during dorsal closure in Drosophilia. November 1, 2009 2009
- Development of Infrared Laser Technology for Human Surgical Applications. May 1, 2009 2009
- (Infrared Laser) Tissue Ablation. March 1, 2009 2009
- Biophysical investigation of dorsal closure during Drosophila embryogenesis. January 1, 2009 2009
- Surgery with pulsed, infrared lasers: applications, mechanisms, and technology. January 1, 2009 2009
- Biophysical investigation of tissue dynamics: dorsal closure during Drosophila embryogenesis as a model system. December 7, 2008 2008
- Biophysical investigation of tissue dynamics: dorsal closure during Drosophila embryogenesis. December 7, 2008 2008
- Dorsal closure during Drosophila development: a model system for biophysical investigations of tissue dynamics. December 7, 2008 2008
- Dorsal closure during Drosophila embryogenesis: Biophysical investigation of tissue dynamics and integrative control. December 7, 2008 2008
- Drosophila morphogenesis: tissue dynamics and emergent properties during dorsal closure. December 7, 2008 2008
- Geometric regulation of tissue dynamics during Drosophila morphogenesis. December 7, 2008 2008
- Two research results: pressure effects in Mark-III FEL tissue ablation and the apoptotic force in Drosophila embryogenesis. December 7, 2008 2008
- Pressure (mechanical) effects in infrared tissue ablation. July 1, 2008 2008
-
Outreach & Engaged Scholarship
-
Service to the Profession
- Panel member : NSF Grant Proposals. October 2013 2013
- PLoS Computational Biology. December 16, 2012 2012
- Developmental Cell. 2012 2012
- Reviewer : PLoS One. December 16, 2011 - December 16, 2012 2011 - 2012
- Reviewer : Proceedings of the National Academy of Sciences. 2011 2011
- Department of Energy, proposal reviews. December 17, 2010 2010
- French National Research Agency, Blue Sky Program (proposal reviews). December 17, 2010 2010
- King Fahd University of Petroleum and Minerals, Saudi Arabia (proposal reviews). December 17, 2010 2010
- PLoS One. December 17, 2010 2010
- European Research Council (proposal reviews). 2010 2010
- Lasers in Engineering. December 16, 2009 2009
- Session Chair, Session entitled Mechanics in Morphogenesis : EMBO Conference Series on Morphogenesis and Dynamics of Multicellular Systems. October 2009 2009
- Engineering in Medicine and Biology Magazine. 2009 2009
- Israel Science Foundation (proposal reviews). 2009 2009
- National Science Foundation (proposal reviews). 2009 - 2010 2009 - 2010
- Proceedings of the National Academy of Sciences USA. 2009 2009
- Proceedings of the National Academy of Science USA. September 2008 - December 7, 2008 2008
Some information on this profile has been compiled automatically from Duke databases and external sources. (Our About page explains how this works.) If you see a problem with the information, please write to Scholars@Duke and let us know. We will reply promptly.