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Eugene Zaverio Oddone

Professor Emeritus of Medicine
Medicine, General Internal Medicine
Durham VA, Health Services Research, Durham, NC 27705
Legacy Tower, 411 W Chapel Hill St., Suite 600, Durham, NC 27711

Featured Works


Characteristics associated with participation in DNA banking: The National Registry of Veterans with ALS.

Journal article Contemp Clin Trials · September 2007 Featured Publication OBJECTIVE: Characteristics that may influence participation in DNA banks are not well defined. The purpose of this study was to examine characteristics associated with participation in a DNA bank among veterans diagnosed with Amyotrophic Lateral Sclerosis ... Full text Link to item Cite

Hypertension Intervention Nurse Telemedicine Study (HINTS): testing a multifactorial tailored behavioral/educational and a medication management intervention for blood pressure control.

Journal article Am Heart J · June 2007 Featured Publication BACKGROUND: Only 31% of Americans with hypertension have their blood pressure (BP) under effective control. We describe a study that tests 3 different interventions in a randomized controlled trial using home BP telemedicine monitoring. METHODS: A sample o ... Full text Link to item Cite

Association of intradialytic blood pressure changes with hospitalization and mortality rates in prevalent ESRD patients.

Journal article Kidney Int · March 2007 Featured Publication The relationship between blood pressure (BP) and clinical outcomes among hemodialysis patients is complex and incompletely understood. This study sought to assess the relationship between blood pressure changes with hemodialysis and clinical outcomes durin ... Full text Link to item Cite

The Take Control of Your Blood pressure (TCYB) study: study design and methodology.

Journal article Contemp Clin Trials · January 2007 Featured Publication BACKGROUND: Among the 65 million Americans with hypertension, only approximately 31% have their blood pressure under control (<140/90 mm/Hg). Despite the damaging impact of hypertension and the availability of evidence-based target values for blood pressur ... Full text Link to item Cite

A multidimensional integrative medicine intervention to improve cardiovascular risk.

Journal article J Gen Intern Med · July 2006 Featured Publication BACKGROUND: Integrative medicine is an individualized, patient-centered approach to health, combining a whole-person model with evidence-based medicine. Interventions based in integrative medicine theory have not been tested as cardiovascular risk-reductio ... Full text Link to item Cite

Racial differences in blood pressure control: potential explanatory factors.

Journal article Am J Med · January 2006 Featured Publication PURPOSE: Poor blood pressure control remains a common problem that contributes to significant cardiovascular morbidity and mortality, particularly among African Americans. We explored antihypertensive medication adherence and other factors that may explain ... Full text Link to item Cite

Racial differences in health concern.

Journal article J Natl Med Assoc · January 2006 Featured Publication An understanding of racial differences in risk-related affect may help explain racial differences in health behaviors and outcomes and provide additional opportunities for intervention. In phone interviews with a random community sample of 197 whites, 155 ... Link to item Cite

Perceived discrimination and reported delay of pharmacy prescriptions and medical tests.

Journal article J Gen Intern Med · July 2005 Featured Publication BACKGROUND: Access to health care varies according to a person's race and ethnicity. Delaying treatment is one measure of access with important health consequences. OBJECTIVE: Determine whether perceptions of unfair treatment because of race or ethnicity a ... Full text Link to item Cite

How well do clinic-based blood pressure measurements agree with the mercury standard?

Journal article J Gen Intern Med · July 2005 Featured Publication BACKGROUND: Obtaining accurate blood pressure (BP) readings is a challenge faced by health professionals. Clinical trials implement strict protocols, whereas clinical practices and studies that assess quality of care utilize a less rigorous protocol for BP ... Full text Link to item Cite

Variations in coronary procedure utilization depending on body mass index.

Journal article Arch Intern Med · June 27, 2005 Featured Publication BACKGROUND: Increased body mass index (BMI) (calculated as weight in kilograms divided by the square of height in meters) is a risk factor for coronary heart disease and is associated with lower preventive services utilization. The relationship between BMI ... Full text Link to item Cite

Patient satisfaction and use of Veterans Affairs versus non-Veterans Affairs healthcare services by veterans.

Journal article Med Care · May 2005 Featured Publication OBJECTIVES: Chronically ill patients who are not satisfied with their care may change healthcare providers or systems, which could disrupt continuity of care and impede management of their conditions. We examined whether patient satisfaction affected subse ... Full text Link to item Cite

Nurse administered telephone intervention for blood pressure control: a patient-tailored multifactorial intervention.

Journal article Patient Educ Couns · April 2005 Featured Publication OBJECTIVES: A randomized controlled trial involving a nurse administered patient-tailored intervention is being conducted to improve blood pressure (BP) control. METHODS: Veterans with hypertension from an outpatient primary care clinic completed a baselin ... Full text Link to item Cite

The veterans' study to improve the control of hypertension (V-STITCH): design and methodology.

Journal article Contemp Clin Trials · April 2005 Featured Publication BACKGROUND: Among the 60 million Americans with hypertension, only approximately 31% have their blood pressure (BP) under control (<140/90 mm Hg). Despite the damaging impact of hypertension and the availability of evidence-based target values for BP, inte ... Full text Link to item Cite

Intentional and unintentional nonadherence to antihypertensive medication.

Journal article Ann Pharmacother · 2005 Featured Publication BACKGROUND: Hypertension is poorly controlled in the US due to medication nonadherence. Recent evidence suggests that nonadherence can be classified as intentional or unintentional and different patient characteristics, such as the experience of adverse ef ... Full text Link to item Cite

Who trusts healthcare institutions? Results from a community-based sample.

Journal article Ethn Dis · 2005 Featured Publication OBJECTIVE: The goal of this research was to examine racial differences in trust in various healthcare institutions. METHOD: In telephone interviews, 195 Whites, 183 Blacks, and 171 Latinos from Durham, NC indicated how often they trust various institutions ... Link to item Cite

Utility of hemoglobin A1c in predicting diabetes risk.

Journal article J Gen Intern Med · December 2004 Featured Publication BACKGROUND: There is controversy surrounding the issue of whether, and how, to screen adults for type 2 diabetes. Our objective was to measure the incidence of new diabetes among outpatients enrolled in a health care system, and to determine whether hemogl ... Full text Link to item Cite

Racial/ethnic variations in non-steroidal anti-inflammatory drug (NSAID) use among patients with osteoarthritis.

Journal article Pharmacoepidemiol Drug Saf · October 2004 Featured Publication PURPOSE: Non-steroidal anti-inflammatory drugs (NSAIDs) are the most commonly prescribed drugs for the treatment of osteoarthritis (OA). While there are documented racial differences in the use of opioid analgesics, little is known about racial differences ... Full text Link to item Cite

The National Registry of Veterans with Amyotrophic Lateral Sclerosis: Department of Veterans Affairs Cooperative Studies Program (CSP) #500a.

Journal article Amyotroph Lateral Scler Other Motor Neuron Disord · September 2004 Featured Publication In response to concern about the development of ALS among veterans of the U.S. armed forces, particularly Gulf War veterans, the Department of Veterans Affairs established a national registry of veterans with ALS. This Registry will identify living veteran ... Full text Link to item Cite

Enrollment in clinical trials according to patients race: experience from the VA Cooperative Studies Program (1975-2000).

Journal article Control Clin Trials · August 2004 Featured Publication BACKGROUND: Racial distribution of clinical trial participants is important because results from these studies serve to define evidence-based practice. This report summarizes the experience of the VA Cooperative Studies Program (CSP) in enrolling white, bl ... Full text Link to item Cite

Patient risk perceptions for carotid endarterectomy: which patients are strongly averse to surgery?

Journal article J Vasc Surg · July 2004 Featured Publication BACKGROUND AND PURPOSE: Patient risk perception for surgery may be central to their willingness to undergo surgery. This study examined potential factors associated with patient aversion of surgery. METHODS: This is a secondary data analysis of a prospecti ... Full text Link to item Cite

Who doesn't receive carotid endarterectomy when appropriate?

Journal article J Vasc Surg · January 2004 Featured Publication OBJECTIVE: The purpose of this study was to identify clinical and nonclinical factors associated with failure to perform carotid endarterectomy (CEA) in patients with clinically appropriate indications. We analyzed data from a prospective cohort study perf ... Full text Link to item Cite

Patient and clinician satisfaction with a store-and-forward teledermatology consult system.

Journal article Telemed J E Health · 2004 Featured Publication The aim of this study was to assess satisfaction with and acceptance of a store and forward teledermatology consult system among patients, referring primary-care clinicians, and consultant dermatologists. As part of a randomized clinical trial that compare ... Full text Link to item Cite

Congestive heart failure patients' perceptions of quality of life: the integration of physical and psychosocial factors.

Journal article Aging Ment Health · January 2004 Featured Publication Congestive heart failure (CHF) lowers survival and worsens the quality of life (QOL) of over four million older Americans. Both clinicians and standardized instruments used to assess the QOL of patients with CHF focus primarily on physical symptoms rather ... Full text Link to item Cite

Nonsteroidal antiinflammatory drug use among patients with GI bleeding.

Journal article Ann Pharmacother · 2004 Featured Publication BACKGROUND: Previous studies have suggested that recommended gastroprotective strategies such as gastroprotective agents (GPAs) and cyclooxygenase (COX) 2 inhibitors may be underutilized among individuals at risk for nonsteroidal antiinflammatory drug (NSA ... Full text Link to item Cite

Racial differences in health care utilization among patients with osteoarthritis.

Journal article J Rheumatol · October 2003 Featured Publication OBJECTIVE: Research has identified racial variations in certain aspects of osteoarthritis (OA) related medical care. We compared health services utilization between African American and white veteran outpatients with OA. METHODS: Subjects were 1612 white a ... Link to item Cite

Clinical identifiers of complicated Staphylococcus aureus bacteremia.

Journal article Arch Intern Med · September 22, 2003 Featured Publication BACKGROUND: Complications of Staphylococcus aureus bacteremia (SAB) are often difficult to identify. The ability to accurately predict the likelihood of these complications would impact patient management. This investigation sought to define readily availa ... Full text Link to item Cite

Staphylococcus aureus bacteremia after median sternotomy: clinical utility of blood culture results in the identification of postoperative mediastinitis.

Journal article Circulation · July 8, 2003 Featured Publication BACKGROUND: Mediastinitis is a complication of coronary artery bypass graft surgery (CABG) that can be difficult to diagnose. This study evaluated the utility of blood culture results in identifying patients with mediastinitis. METHODS AND RESULTS: All uni ... Full text Link to item Cite

Is specialty care associated with improved survival of patients with congestive heart failure?

Journal article Am Heart J · February 2003 Featured Publication BACKGROUND: Implementation of the complex treatment strategies that have been shown to improve survival of patients with congestive heart failure (CHF) may require certain expertise. We wanted to examine the association between pattern of outpatient care a ... Full text Link to item Cite

Quality of care for patients diagnosed with diabetes at screening.

Journal article Diabetes Care · February 2003 Featured Publication OBJECTIVE: Screening for diabetes has the potential to be an effective intervention, especially if patients have intensive treatment of their newly diagnosed diabetes and comorbid hypertension. We wished to determine the process and quality of diabetes car ... Full text Link to item Cite

Racial differences in survival post cerebral infarction among the elderly.

Journal article Neurology · January 28, 2003 Featured Publication OBJECTIVE: To investigate whether there are differences in poststroke survival between African American and white patients, aged 65 and over, in the United States. METHODS: A biracial cohort of patients was selected from a random 20% national sample of Med ... Full text Link to item Cite

Improving the quality of anticoagulation of patients with atrial fibrillation in managed care organizations: results of the managing anticoagulation services trial.

Journal article Am J Med · July 2002 Featured Publication Randomized trials have indicated that well-managed anticoagulation with warfarin could prevent more than half of the strokes related to atrial fibrillation. However, many patients with atrial fibrillation who are eligible for this therapy either do not rec ... Full text Link to item Cite

Impact of diabetes screening on quality of life.

Journal article Diabetes Care · June 2002 Featured Publication OBJECTIVE: Diagnosis of a chronic illness can have a negative impact on patients' perception of their well-being ("labeling" effect). We sought to determine the effects of a new diagnosis of diabetes, discovered by systematic screening, on patients' health ... Full text Link to item Cite

A model of psychosocial and cultural antecedents of blood pressure control.

Journal article J Natl Med Assoc · April 2002 Featured Publication Hypertension is a major modifiable risk factor for stroke, congestive heart failure, and end-stage renal disease. Hypertension is particularly prevalent and deadly among African Americans. Effective treatment for hypertension has been available for decades ... Link to item Cite

Screening for diabetes in an outpatient clinic population.

Journal article J Gen Intern Med · January 2002 Featured Publication BACKGROUND: Opportunistic disease screening is the routine, asymptomatic disease screening of patients at the time of a physician encounter for other reasons. While the prevalence of unrecognized diabetes in community populations is well known, the prevale ... Full text Link to item Cite

Primary care for patients infected with human immunodeficiency virus: a randomized controlled trial.

Journal article J Gen Intern Med · September 2001 Featured Publication OBJECTIVE: To measure the impact of a teaching intervention and to compare process and outcomes of care for HIV-infected patients randomly assigned to a general medicine clinic (GMC) or an infectious disease clinic (IDC) for primary care. DESIGN: Prospecti ... Full text Link to item Cite

Multisite randomized controlled trials in health services research: scientific challenges and operational issues.

Journal article Med Care · June 2001 Featured Publication Although well-designed randomized controlled trials (RCT) provide the strongest evidence regarding causation, only relatively recently have they been used by health services researchers to study the organization, delivery, quality, and outcomes of care. Mo ... Full text Link to item Cite

Culturally-sensitive weight loss program produces significant reduction in weight, blood pressure, and cholesterol in eight weeks.

Journal article J Natl Med Assoc · November 2000 Featured Publication Dietary and behavioral needs of special populations are rarely considered in traditional weight loss programs. This study assessed the impact of culturally-sensitive modifications to the Duke University Rice Diet weight loss program for African-American di ... Link to item Cite

Community impact of anticoagulation services: rationale and design of the Managing Anticoagulation Services Trial (MAST).

Journal article J Thromb Thrombolysis · June 2000 Featured Publication We describe the design of the Managing Anti-coagulation Services Trial (MAST), a practice-improvement trial testing whether anticoagulation services are a preferred method of managing anticoagulation for stroke prevention among patients with atrial fibrill ... Full text Link to item Cite

Racial variation in initial stroke severity.

Journal article Stroke · March 2000 Featured Publication BACKGROUND AND PURPOSE: Blacks experience greater morbidity and mortality from stroke than do whites. The degree to which this is due to the severity of the initial stroke is not known. The objective of this study is to determine whether there is a racial ... Full text Link to item Cite

Race, presenting signs and symptoms, use of carotid artery imaging, and appropriateness of carotid endarterectomy.

Journal article Stroke · July 1999 Featured Publication BACKGROUND AND PURPOSE: We sought to determine whether there are racial differences in use of carotid artery imaging after controlling for clinical factors and to ascertain racial differences in presenting signs and symptoms and overall appropriateness for ... Full text Link to item Cite

Understanding racial variation in the use of carotid endarterectomy: the role of aversion to surgery.

Journal article J Natl Med Assoc · January 1998 Featured Publication Previous studies indicate that African-American patients undergo carotid endarterectomy at one fourth the rate of white patients. This study was undertaken to determine if differences in aversion to carotid endarterectomy might account for some of the raci ... Link to item Cite

Classifying general medicine readmissions. Are they preventable? Veterans Affairs Cooperative Studies in Health Services Group on Primary Care and Hospital Readmissions.

Journal article J Gen Intern Med · October 1996 Featured Publication OBJECTIVES: To describe a new quality assessment method used to classify the preventability of hospitalization in terms of patient, clinician, or system factors. DESIGN: The instrument was developed in two phases. Phase 1 was a prospective comparison of ad ... Full text Link to item Cite

Theories explaining racial differences in the utilization of diagnostic and therapeutic procedures for cerebrovascular disease.

Journal article Milbank Q · 1995 Featured Publication Despite a higher risk of stroke, blacks are less likely than whites to receive the invasive procedures that are used to diagnose and treat cerebrovascular disease, particularly carotid endarterectomy. Explanations for the lower rate of procedural use inclu ... Link to item Cite

Teaching cardiovascular examination skills: results from a randomized controlled trial.

Journal article Am J Med · October 1993 Featured Publication PURPOSE: To evaluate the effectiveness of a teaching program designed to improve interns' cardiovascular examination skills. PARTICIPANTS: All 56 interns rotating on a mandatory 4-week inpatient cardiology service during 1 academic year (July 1989-June 199 ... Full text Link to item Cite