Scholars@Duke

• Background
• 

  Education, Training, & Certifications

  • Nephrology Fellowship, Medicine, Duke University School of Medicine 2011 - 2015
  • Internal Medicine Residency, Medicine, Duke University School of Medicine 2007 - 2010
  • MD./PhD., University of Maryland - Baltimore 2007
• 

  Duke Appointment History

  • Medical Instructor in the Department of Medicine, Medicine, Nephrology, Medicine 2015 - 2018
• Recognition
• 

  In the News

  • APR 4, 2018

    Duke Med School Blog

    Five SoM Physician-Scientists Selected to Receive Strong Start Awards
• Research
• 

  Selected Grants

  • The Role of Interleukin-15 Receptor-alpha Variants in the Pathogenesis of FSGS awarded by National Institutes of Health 2017 - 2022
• Publications & Artistic Works
• 

  Selected Publications

  • Journal Articles

    • Hall, G, Lane, BM, Khan, K, Pediaditakis, I, Xiao, J, Wu, G, Wang, L, Kovalik, ME, Chryst-Stangl, M, Davis, EE, Spurney, RF, and Gbadegesin, RA. "The Human FSGS-Causing ANLN R431C Mutation Induces Dysregulated PI3K/AKT/mTOR/Rac1 Signaling in Podocytes." Journal of the American Society of Nephrology : Jasn 29, no. 8 (August 2018): 2110-2122.  Full Text
    • Hall, G, and Spurney, RF. "Losing their footing: Rac1 signaling causes podocyte detachment and FSGS." Kidney international 92, no. 2 (August 2017): 283-285.  Full Text
    • Hall, G, Routh, JC, and Gbadegesin, RA. "Urinary Anomalies in 22q11.2 Deletion (DiGeorge syndrome): From Copy Number Variations to Single-Gene Determinants of Phenotype." American journal of kidney diseases : the official journal of the National Kidney Foundation 70, no. 1 (July 2017): 8-10.  Full Text
    • Hall, G, Lane, B, Chryst-Ladd, M, Wu, G, Lin, J-J, Qin, X, Hauser, ER, and Gbadegesin, R. "Dysregulation of WTI (-KTS) is Associated with the Kidney-Specific Effects of the LMX1B R246Q Mutation." Scientific Reports 7 (January 6, 2017): 39933-null.  Full Text
    • Elahi, S, Homstad, A, Vaidya, H, Stout, J, Hall, G, Wu, G, Conlon, P, Routh, JC, Wiener, JS, Ross, SS, Nagaraj, S, Wigfall, D, Foreman, J, Adeyemo, A, Gupta, IR, Brophy, PD, Rabinovich, CE, and Gbadegesin, RA. "Rare variants in tenascin genes in a cohort of children with primary vesicoureteric reflux." Pediatric nephrology (Berlin, Germany) 31, no. 2 (February 2016): 247-253.  Full Text
    • Phelan, PJ, Hall, G, Wigfall, D, Foreman, J, Nagaraj, S, Malone, AF, Winn, MP, Howell, DN, and Gbadegesin, R. "Variability in phenotype induced by the podocin variant R229Q plus a single pathogenic mutation." Clinical kidney journal 8, no. 5 (October 2015): 538-542.  Full Text  Open Access Copy
    • Gbadegesin, RA, Adeyemo, A, Webb, NJA, Greenbaum, LA, Abeyagunawardena, A, Thalgahagoda, S, Kale, A, Gipson, D, Srivastava, T, Lin, J-J, Chand, D, Hunley, TE, Brophy, PD, Bagga, A, Sinha, A, Rheault, MN, Ghali, J, Nicholls, K, Abraham, E, Janjua, HS, Omoloja, A, Barletta, G-M, Cai, Y, Milford, DD, O'Brien, C, Awan, A, Belostotsky, V, Smoyer, WE, Homstad, A, Hall, G, Wu, G, Nagaraj, S, Wigfall, D, Foreman, J, Winn, MP, and Mid-West Pediatric Nephrology Consortium, . "HLA-DQA1 and PLCG2 Are Candidate Risk Loci for Childhood-Onset Steroid-Sensitive Nephrotic Syndrome." Journal of the American Society of Nephrology : Jasn 26, no. 7 (July 2015): 1701-1710.  Full Text
    • Hall, G, and Gbadegesin, RA. "Translating genetic findings in hereditary nephrotic syndrome: the missing loops." American Journal of Physiology. Renal Physiology 309, no. 1 (July 2015): F24-F28. (Review)  Full Text
    • Hall, G, Gbadegesin, RA, Lavin, P, Wu, G, Liu, Y, Oh, EC, Wang, L, Spurney, RF, Eckel, J, Lindsey, T, Homstad, A, Malone, AF, Phelan, PJ, Shaw, A, Howell, DN, Conlon, PJ, Katsanis, N, and Winn, MP. "A novel missense mutation of Wilms' Tumor 1 causes autosomal dominant FSGS." Journal of the American Society of Nephrology : Jasn 26, no. 4 (April 2015): 831-843.  Full Text
    • Gbadegesin, RA, Hall, G, Adeyemo, A, Hanke, N, Tossidou, I, Burchette, J, Wu, G, Homstad, A, Sparks, MA, Gomez, J, Jiang, R, Alonso, A, Lavin, P, Conlon, P, Korstanje, R, Stander, MC, Shamsan, G, Barua, M, Spurney, R, Singhal, PC, Kopp, JB, Haller, H, Howell, D, Pollak, MR, Shaw, AS, Schiffer, M, and Winn, MP. "Mutations in the gene that encodes the F-actin binding protein anillin cause FSGS." Journal of the American Society of Nephrology : Jasn 25, no. 9 (September 2014): 1991-2002.  Full Text
    • Hall, G, Rowell, J, Farinelli, F, Gbadegesin, RA, Lavin, P, Wu, G, Homstad, A, Malone, A, Lindsey, T, Jiang, R, Spurney, R, Tomaselli, GF, Kass, DA, and Winn, MP. "Phosphodiesterase 5 inhibition ameliorates angiontensin II-induced podocyte dysmotility via the protein kinase G-mediated downregulation of TRPC6 activity." American journal of physiology. Renal physiology 306, no. 12 (June 2014): F1442-F1450.  Full Text
    • Malone, AF, Phelan, PJ, Hall, G, Cetincelik, U, Homstad, A, Alonso, AS, Jiang, R, Lindsey, TB, Wu, G, Sparks, MA, Smith, SR, Webb, NJA, Kalra, PA, Adeyemo, AA, Shaw, AS, Conlon, PJ, Jennette, JC, Howell, DN, Winn, MP, and Gbadegesin, RA. "Rare hereditary COL4A3/COL4A4 variants may be mistaken for familial focal segmental glomerulosclerosis." Kidney International 86, no. 6 (January 1, 2014): 1253-1259.  Full Text
    • Gbadegesin, RA, Brophy, PD, Adeyemo, A, Hall, G, Gupta, IR, Hains, D, Bartkowiak, B, Rabinovich, CE, Chandrasekharappa, S, Homstad, A, Westreich, K, Wu, G, Liu, Y, Holanda, D, Clarke, J, Lavin, P, Selim, A, Miller, S, Wiener, JS, Ross, SS, Foreman, J, Rotimi, C, and Winn, MP. "TNXB mutations can cause vesicoureteral reflux." J Am Soc Nephrol 24, no. 8 (July 2013): 1313-1322.  Full Text  Link to Item
    • "CORRECTION." Journal of the American Society of Nephrology 24, no. 1 (January 1, 2013): 160-160.  Full Text
    • Gbadegesin, RA, Lavin, PJ, Hall, G, Bartkowiak, B, Homstad, A, Jiang, R, Wu, G, Byrd, A, Lynn, K, Wolfish, N, Ottati, C, Stevens, P, Howell, D, Conlon, P, and Winn, MP. "Inverted formin 2 mutations with variable expression in patients with sporadic and hereditary focal and segmental glomerulosclerosis." Kidney International 81, no. 1 (January 2012): 94-99.  Full Text
    • Luo, X, Hall, G, Li, S, Bird, A, Lavin, PJ, Winn, MP, Kemper, AR, Brown, TT, and Koeberl, DD. "Hepatorenal correction in murine glycogen storage disease type I with a double-stranded adeno-associated virus vector." Molecular Therapy : the Journal of the American Society of Gene Therapy 19, no. 11 (November 2011): 1961-1970.  Full Text
    • Eckel, J, Lavin, PJ, Finch, EA, Mukerji, N, Burch, J, Gbadegesin, R, Wu, G, Bowling, B, Byrd, A, Hall, G, Sparks, M, Zhang, ZS, Homstad, A, Barisoni, L, Birbaumer, L, Rosenberg, P, and Winn, MP. "TRPC6 enhances angiotensin II-induced albuminuria." J Am Soc Nephrol 22, no. 3 (March 2011): 526-535.  Full Text  Link to Item
    • Rogers, TB, Pati, S, Gaa, S, Riley, D, Khakoo, AY, Patel, S, Wardlow, RD, Frederick, CA, Hall, G, He, L-P, and Lederer, WJ. "Mesenchymal stem cells stimulate protective genetic reprogramming of injured cardiac ventricular myocytes." Journal of molecular and cellular cardiology 50, no. 2 (February 2011): 346-356.  Full Text
    • Hall, G, Hasday, JD, and Rogers, TB. "Regulating the regulator: NF-kappaB signaling in heart." Journal of Molecular and Cellular Cardiology 41, no. 4 (October 2006): 580-591. (Review)  Full Text
    • Weiner, CP, Mason, C, Hall, G, Ahmad, U, Swaan, P, and Buhimschi, IA. "Pregnancy and estradiol modulate myometrial G-protein pathways in the guinea pig." American journal of obstetrics and gynecology 195, no. 1 (July 2006): 275-287.  Full Text
    • Khakoo, AY, Pati, S, Anderson, SA, Reid, W, Elshal, MF, Rovira, II, Nguyen, AT, Malide, D, Combs, CA, Hall, G, Zhang, J, Raffeld, M, Rogers, TB, Stetler-Stevenson, W, Frank, JA, Reitz, M, and Finkel, T. "Human mesenchymal stem cells exert potent antitumorigenic effects in a model of Kaposi's sarcoma." The Journal of Experimental Medicine 203, no. 5 (May 2006): 1235-1247.  Full Text
    • Hall, G, Singh, IS, Hester, L, Hasday, JD, and Rogers, TB. "Inhibitor-kappaB kinase-beta regulates LPS-induced TNF-alpha production in cardiac myocytes through modulation of NF-kappaB p65 subunit phosphorylation." American Journal of Physiology. Heart and Circulatory Physiology 289, no. 5 (November 2005): H2103-H2111.  Full Text
    • Wright, G, Singh, IS, Hasday, JD, Farrance, IK, Hall, G, Cross, AS, and Rogers, TB. "Endotoxin stress-response in cardiomyocytes: NF-kappaB activation and tumor necrosis factor-alpha expression." American Journal of Physiology. Heart and Circulatory Physiology 282, no. 3 (March 2002): H872-H879.  Full Text
    • Buhimschi, IA, Hall, G, Thompson, LP, and Weiner, CP. "Pregnancy and estradiol decrease GTPase activity in the guinea pig uterine artery." American Journal of Physiology. Heart and Circulatory Physiology 281, no. 5 (November 2001): H2168-H2175.  Full Text

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