Skip to main content

George A. Truskey

R. Eugene and Susie E. Goodson Distinguished Professor of Biomedical Engineering
Biomedical Engineering
Box 90281, Durham, NC 27708-0281
1395 FCIEMAS, 101 Science Drive, Durham, NC 27708-0281

Scholarly Works - Conferences


Investigating the impact of sickle cell disease on red blood cell transport in complex capillary networks.

Conference Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference · July 2024 Sickle cell disease encompasses a variety of inherited red blood cell (RBC) disorders characterized by abnormal thrombosis, microvascular occlusion, end-organ ischemia, and early mortality. Understanding how sickle RBCs drive abnormal blood flow and stress ... Full text Cite

Patient- and Ventilator-Specific Modeling to Drive the Use and Development of 3D Printed Devices for Rapid Ventilator Splitting During the COVID-19 Pandemic

Conference Lecture Notes in Computer Science Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics · January 1, 2022 In the early days of the COVID-19 pandemic, there was a pressing need for an expansion of the ventilator capacity in response to the COVID19 pandemic. Reserved for dire situations, ventilator splitting is complex, and has previously been limited to patient ... Full text Cite

A novel in situ monitoring system of 3D engineered muscle

Conference 21st International Conference on Miniaturized Systems for Chemistry and Life Sciences Microtas 2017 · January 1, 2020 In this work, we developed an in situ force monitoring system of skeletal muscle based on “ecoflex-coupling method”. The three dimensional (3D) human skeletal muscle myobundles was fabricated in series with ecoflex (platinum-catalyzed silicones) film conta ... Cite

Abstract P284: The Chemotherapeutic Agent Docetaxel Disrupts Mitochondrial Energetics in 3D Human Bioengineered Myobundles

Conference Circulation · March 5, 2019 Taxanes (i.e. docetaxel, (TAX)) comprise the first line-treatment for breast cancer (BC), mostly in combination with anthracyclines like doxorubicin (DOX). The efficacy of these drugs as antineoplastic agents has helped to boost 10-yea ... Full text Cite

ECHOCARDIOGRAPHIC MEASUREMENT OF CARDIAC TWIST: A SYSTEMATIC REVIEW AND META-ANALYSIS

Conference Journal of the American College of Cardiology · March 2018 Full text Cite

Tissue-Engineered Human Skeletal Muscle Model of Rheumatoid Arthritis

Conference TISSUE ENGINEERING PART A · December 1, 2017 Link to item Cite

In Situ Monitoring of Engineering Muscle to Assess Myopathy

Conference TISSUE ENGINEERING PART A · December 1, 2017 Link to item Cite

Tissue-Engineered Human Skeletal Muscle Model of Rheumatoid Arthritis

Conference ARTHRITIS & RHEUMATOLOGY · October 1, 2017 Link to item Cite

Human Tissue Engineered Blood Vessels for in vitro Drug Testing

Conference TISSUE ENGINEERING PART A · September 1, 2015 Link to item Cite

Novel In Vitro Exercise Model of Engineered Human Skeletal Muscle

Conference TISSUE ENGINEERING PART A · September 1, 2015 Link to item Cite

Viscoelastic Cell Adhesion Model (VECAM)

Conference Biophysical Journal · January 2013 Full text Cite

Dynamic quantitative microscopy and nanoscopy of red blood cells in sickle cell disease

Conference Progress in Biomedical Optics and Imaging Proceedings of SPIE · April 16, 2012 We have applied wide-field digital interferometric techniques to quantitatively image sickle red blood cells (RBCs) [1] in a noncontact label-free manner, and measure the nanometer-scale fluctuations in their thickness as an indication of their stiffness. ... Full text Cite

Three-dimensional computational modeling of leukocyte rolling and adhesion

Conference 2006 ASME Joint U S European Fluids Engineering Summer Meeting Fedsm 2006 · December 1, 2006 Recruitment of leukocytes into sites of acute and chronic inflammation is a vital component of the innate immune response in humans and plays an important role in cardiovascular diseases, such as ischemia-reperfusion injury and atherosclerosis. Leukocytes ... Cite

Three-dimensional computational modeling of leukocyte rolling and adhesion

Conference Proceedings of ASME Fluids Engineering Division Summer Meeting 2006 Fedsm2006 · January 1, 2006 Recruitment of leukocytes into sites of acute and chronic inflammation is a vital component of the innate immune response in humans and plays an important role in cardiovascular diseases, such as ischemia-reperfusion injury and atherosclerosis. Leukocytes ... Full text Cite

Real-time theoretical compartmental model of blood-brain barrier drug delivery.

Conference Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference · January 2004 This study developed upon the Mahar Doan and Boje simulations to create a novel pharmacokinetic/pharmacodynamic real-time compartmental model in Simulink. The model allowed for varying combinations of oral and intravenous drug dosing under steady and nonst ... Full text Cite

THE ZERO-TENSION HYPOTHESIS FOR THE MECHANISM OF ATHEROGENESIS AND THE WALL SHEAR STRESS GRADIENT (WSSG) PREDICTOR EQUATION

Conference ASME International Mechanical Engineering Congress and Exposition Proceedings Imece · January 1, 1996 Full text Cite

TOTAL INTERNAL-REFLECTION FLUORESCENCE VIDEO MICROSCOPY OF CELL-SURFACE CONTACTS

Conference ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY · September 10, 1989 Link to item Cite

METABOLIC STUDIES OF HYBRIDOMAS IN FED-BATCH BIOREACTOR

Conference ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY · September 25, 1988 Link to item Cite