Current Appointments & Affiliations
Allan H. Friedman Distinguished Professor of Neurosurgery
·
2023 - Present
Neurosurgery,
Neurosurgery
Professor of Neurosurgery
·
2022 - Present
Neurosurgery,
Neurosurgery
Chair, Department of Neurosurgery
·
2022 - Present
Neurosurgery,
Neurosurgery
Professor in Neurobiology
·
2022 - Present
Neurobiology,
Basic Science Departments
Professor in Pediatrics
·
2023 - Present
Pediatrics,
Clinical Science Departments
Professor in Neurology
·
2024 - Present
Neurology,
Clinical Science Departments
Member of the Duke Cancer Institute
·
2022 - Present
Duke Cancer Institute,
Institutes and Centers
Faculty Network Member of the Duke Institute for Brain Sciences
·
2023 - Present
Duke Institute for Brain Sciences,
University Institutes and Centers
Recent Publications
A surgical window of opportunity trial evaluating the effect of the PCSK9 inhibitor evolocumab on tumoral MHC-I expression and CD8+ infiltration in glioma.
Journal Article Sci Rep · October 23, 2025 Many cancers evade immunosurveillance by downregulating surface major histocompatibility class (MHC)-I. Proprotein convertase subtilisin/kexin type 9 (PCSK9) promotes MHC-I degradation and is elevated in glioma. Evolocumab is a clinically approved PCSK9 in ... Full text Link to item CiteComprehensive pediatric neurosurgical implant checklist to maintain low implant infection rates: lessons on compliance and institutional culture.
Journal Article J Neurosurg Pediatr · October 1, 2025 OBJECTIVE: Implant infection is a significant contributor to morbidity and mortality for children with hydrocephalus and other neurosurgical conditions requiring shunts and other neurosurgical implants. To standardize pediatric neurosurgical care and minim ... Full text Open Access Link to item CiteOptimal stimulation of the thalamic centromedian nucleus in children with Lennox-Gastaut syndrome: patient series.
Journal Article J Neurosurg Case Lessons · September 22, 2025 BACKGROUND: Lennox-Gastaut syndrome (LGS) is a severe developmental and epileptic encephalopathy characterized by multiple seizure types, intellectual disability, and distinctive EEG findings. Deep brain stimulation of the centromedian nucleus (CM-DBS) is ... Full text Open Access Link to item CiteRecent Grants
Development of Patient Reported Outcome Measure, Validation of Clinical Outcome Measures, Natural History, and Intervention for Mild
ResearchPrincipal Investigator · Awarded by Drexel University · 2025 - 2028Identification and molecular characterization of somatic mutations in MCD
ResearchPrincipal Investigator · Awarded by University of North Carolina - Chapel Hill · 2024 - 2028A Risk Stratification Model for Health and Academic Outcomes in Children with Concussion Based on Novel Symptom Trajectory Typologies
ResearchSignificant Contributor · Awarded by National Institutes of Health · 2023 - 2028View All Grants
Education, Training & Certifications
Stanford University ·
1994
M.D.