Scholarly Works - Book sections
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January 1, 2024
Antigen-specific Cytotoxic T Lymphocytes (CTLs) can be detected by measuring responsiveness to major histocompatibility complex class I (MHC-I)-presented peptide as the ability to produce cytokines/chemokines or to eliminate target cells. Functional assays ...
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January 1, 2024
The enzyme-linked immunospot (ELISPOT) assay to detect T cell responses was developed based on the initial technique reported by Czerkinsky et al. in 1983 as an alternative to the plaque-forming assay for the detection of antibody-secreting cells. In an ef ...
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June 1, 2022
A greater understanding of the immune response, particularly of cell-mediated immune responses in malaria, tuberculosis (TB), human immunodeficiency virus (HIV), and cancer patients, will lead to improved vaccine design. Currently, in vitro analyses of cel ...
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April 8, 2008
An HIV-1 vaccine is the best public health tool for stemming the AIDS pandemic, now in its third decade. Studies from HIV-1 infected humans who control infection, animal model experiments, as well as historic experience with licensed vaccines suggest that ...
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