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Glenn Michael Preminger

James F. Glenn, M.D. Distinguished Professor of Urology
Urology
Box 3167 Med Ctr, Durham, NC
30 Duke Medicine Circle, RM1573 Duke South, White Zone, Durham, NC 27710
Office hours Mondays 8:30 -  4:00

Wednesdays 8:30 - 2:00  

Featured Works


Optical performance comparison of deflectable laparoscopes for laparoendoscopic single-site surgery.

Journal article J Endourol · October 2012 Featured Publication BACKGROUND AND PURPOSE: Flexible working angles and fine optical visualization are major requisite factors in performing laparoendoscopic single-site (LESS) urologic procedures. Multiple mechanical design approaches have been used to develop deflectable la ... Full text Link to item Cite

Organ-specific radiation dose rates and effective dose rates during percutaneous nephrolithotomy.

Journal article J Endourol · May 2012 Featured Publication BACKGROUND AND PURPOSE: Radiation exposure during medical procedures continues to be an increasing concern for physicians and patients. We determined organ-specific dose rates and calculated effective dose rates during right and left percutaneous nephrolit ... Full text Link to item Cite

Contemporary management of ureteral stones.

Journal article Eur Urol · April 2012 Featured Publication CONTEXT: Ureteral calculi represent a common condition that urologists encounter in everyday practice. Several treatment options are available for calculi that do not pass spontaneously or are unlikely to do so. OBJECTIVE: In this nonsystematic review, we ... Full text Link to item Cite

Risk reduction strategy for radiation exposure during percutaneous nephrolithotomy.

Journal article Curr Opin Urol · March 2012 Featured Publication PURPOSE OF REVIEW: To discuss the risk of radiation exposure to patients with nephrolithiasis. To review the risk factors for increased radiation exposure to patients during percutaneous nephrolithotomy (PNL) from fluoroscopy. To review the techniques to r ... Full text Link to item Cite

Determination of patient radiation dose during ureteroscopic treatment of urolithiasis using a validated model.

Journal article J Urol · March 2012 Featured Publication PURPOSE: We measured organ specific radiation dose rates and determined effective dose rates during simulated ureteroscopy using a validated model. To calculate the effective dose, patients were exposed to ureteroscopic management of stones at our institut ... Full text Link to item Cite

Kidney stones.

Journal article BMJ Clin Evid · November 10, 2011 Featured Publication INTRODUCTION: The age of peak incidence for stone disease is 20 to 40 years, although stones are seen in all age groups. There is a male to female ratio of 3:2. METHODS AND OUTCOMES: We conducted a systematic review and aimed to answer the following clinic ... Link to item Cite

Results of a 5-year multicenter trial of a new generation cooled high energy transurethral microwave thermal therapy catheter for benign prostatic hyperplasia.

Journal article J Urol · May 2011 Featured Publication PURPOSE: We determined the safety, effectiveness and 5-year durability of the new generation, cooled, high energy microwave treatment Cooled ThermoCath® catheter with the Targis® cooled high energy transurethral microwave thermal therapy system by performi ... Full text Link to item Cite

Reduced radiation exposure with the use of an air retrograde pyelogram during fluoroscopic access for percutaneous nephrolithotomy.

Journal article J Endourol · April 2011 Featured Publication INTRODUCTION: Fluoroscopy with retrograde pyelogram is commonly used to obtain access for percutaneous nephrolithotomy (PNL). Our practice uses room air for retrograde identification of calyceal anatomy. Herein we explore whether an air pyelogram was assoc ... Full text Link to item Cite

Randomized controlled, multicentre clinical trial comparing a dual-probe ultrasonic lithotrite with a single-probe lithotrite for percutaneous nephrolithotomy.

Journal article BJU Int · March 2011 Featured Publication OBJECTIVES: • To compare the Cyberwand (Gyrus/ACMI, Southborough, MA, USA), a dual-probe ultrasonic lithotrite, with a single-probe ultrasonic lithotrite. • The Cyberwand incorporates coaxial high- and low-frequency ultrasonic probes that work synergistica ... Full text Link to item Cite

Low dose computerized tomography for detection of urolithiasis--its effectiveness in the setting of the urology clinic.

Journal article J Urol · March 2011 Featured Publication PURPOSE: Low dose noncontrast computerized tomography is becoming a common imaging tool to diagnose urolithiasis. We investigated its usefulness as a diagnostic tool in the outpatient setting. MATERIALS AND METHODS: A total of 62 patients with suspected ur ... Full text Link to item Cite

Factors affecting patient radiation exposure during percutaneous nephrolithotomy.

Journal article J Urol · December 2010 Featured Publication PURPOSE: We identified patient and stone characteristics that may contribute to increased radiation exposure during percutaneous nephrolithotomy and offer technique modifications to limit the radiation dose. MATERIAL AND METHODS: We reviewed the records of ... Full text Link to item Cite

In vivo determination of urinary stone composition using dual energy computerized tomography with advanced post-acquisition processing.

Journal article J Urol · December 2010 Featured Publication PURPOSE: We assessed whether dual energy computerized tomography with advanced post-image processing can accurately differentiate urinary calculi composition in vivo. MATERIALS AND METHODS: A total of 25 patients scheduled to undergo ureteroscopic/percutan ... Full text Link to item Cite

Tubeless percutaneous nephrolithotomy--the new standard of care?

Journal article J Urol · October 2010 Featured Publication PURPOSE: Traditionally the placement of a nephrostomy tube at the conclusion of percutaneous nephrolithotomy is considered the standard of care. However, the need for nephrostomy tube placement has been questioned by numerous authors. We evaluated the lite ... Full text Link to item Cite

A simple method for fabricating artificial kidney stones of different physical properties.

Journal article Urol Res · August 2010 Featured Publication A simple method for preparing artificial kidney stones with varying physical properties is described. BegoStone was prepared with a powder-to-water ratio ranging from 15:3 to 15:6. The acoustic properties of the phantoms were characterized using an ultraso ... Full text Link to item Cite

High burden and complex renal calculi: aggressive percutaneous nephrolithotomy versus multi-modal approaches.

Journal article Arch Ital Urol Androl · March 2010 Featured Publication INTRODUCTION: Percutaneous nephrolithotomy (PNL) remains the treatment of choice for managing patients with large or complex renal calculi, especially staghorn stones composed of struvite. Recent advances in the PNL technique appear to improve post-operati ... Link to item Cite

Stone forming risk factors in patients with type Ia glycogen storage disease.

Journal article J Urol · March 2010 Featured Publication PURPOSE: Patients with type Ia glycogen storage disease have an increased recurrent nephrolithiasis rate. We identified stone forming risk factors in patients with type Ia glycogen storage disease vs those in stone formers without the disease. MATERIALS AN ... Full text Link to item Cite

A novel drug eluting ureteral stent: a prospective, randomized, multicenter clinical trial to evaluate the safety and effectiveness of a ketorolac loaded ureteral stent.

Journal article J Urol · March 2010 Featured Publication PURPOSE: We evaluated the short-term safety and efficacy of a ketorolac loaded ureteral stent compared to a standard stent (control). MATERIALS AND METHODS: In this prospective, multicenter, double-blind study patients were randomized 1:1 to ketorolac load ... Full text Link to item Cite

Percutaneous nephrolithotomy: an extreme technical makeover for an old technique.

Journal article Arch Ital Urol Androl · March 2010 Featured Publication INTRODUCTION: Percutaneous nephrolithotomy (PNL) remains the treatment of choice for several forms of stone disease including: large stones, many cystine and struvite calculi, lower pole calyceal calculi, stones associated with anomalous renal anatomy, and ... Link to item Cite

Dual-energy computed tomography with advanced postimage acquisition data processing: improved determination of urinary stone composition.

Journal article J Endourol · March 2010 Featured Publication INTRODUCTION: The characterization of urinary calculi using noninvasive methods has the potential to affect clinical management. CT remains the gold standard for diagnosis of urinary calculi, but has not reliably differentiated varying stone compositions. ... Full text Open Access Link to item Cite

Long-term results of percutaneous nephrolithotomy: does prophylactic medical stone management make a difference?

Journal article J Endourol · October 2009 Featured Publication It has been almost 30 years since the introduction of percutaneous nephrolithotomy (PCNL) as a safe, effective, and efficient method for large stone fragmentation and removal. While considered a highly effective technique, a surgical procedure alone cannot ... Full text Link to item Cite

Assessing the impact of ureteral stent design on patient comfort.

Journal article J Urol · June 2009 Featured Publication PURPOSE: We assessed the near term comfort of newly designed ureteral study stents or marketed control stents, including Polaris and Percuflex stents. Study stents had distal 6Fr pigtail ends with 3Fr or less loops. Decreased material in situ was hypothesi ... Full text Link to item Cite

Renal stone assessment with dual-energy multidetector CT and advanced postprocessing techniques: improved characterization of renal stone composition--pilot study.

Journal article Radiology · March 2009 Featured Publication PURPOSE: To prospectively evaluate the capability of noninvasive, simultaneous dual-energy (DE) multidetector computed tomography (CT) to improve characterization of human renal calculi in an anthropomorphic DE renal phantom by introducing advanced postpro ... Full text Link to item Cite

Impact of long-term potassium citrate therapy on urinary profiles and recurrent stone formation.

Journal article J Urol · March 2009 Featured Publication PURPOSE: Potassium citrate therapy has become one of the cornerstones of medical stone management. We elucidated the long-term effects of potassium citrate on urinary metabolic profiles and its impact on stone formation rates. MATERIALS AND METHODS: We per ... Full text Link to item Cite

High definition laparoscopy: objective assessment of performance characteristics and comparison with standard laparoscopy.

Journal article J Endourol · March 2009 Featured Publication INTRODUCTION: High definition (HD) digital imaging represents a major advance in endoscope technology. The development of the charge-coupled device chip and its location at the distal end of the endoscope allows for image capture and digitization, as well ... Full text Link to item Cite

Radiation exposure in the acute and short-term management of urolithiasis at 2 academic centers.

Journal article J Urol · February 2009 Featured Publication PURPOSE: Diagnostic imaging has a central role in the evaluation and management of urolithiasis. A variety of modalities are available, each with benefits and limitations. Without careful consideration of imaging modalities in quantity and type patients ma ... Full text Link to item Cite

Adjuvant therapy after surgical stone management.

Journal article Adv Chronic Kidney Dis · January 2009 Featured Publication The aim of this article was to review the most widely researched adjuvant medical therapies for the surgical management of urolithiasis. Articles were identified and reviewed from PubMed and Medline databases with MeSH headings focusing on the various surg ... Full text Link to item Cite

Beyond prone position in percutaneous nephrolithotomy: a comprehensive review.

Journal article Eur Urol · December 2008 Featured Publication CONTEXT: Percutaneous nephrolithotomy (PNL) is traditionally performed with the patient in the prone position. OBJECTIVE: To assess the efficacy and safety of the prone and supine positions, particularly in obese patients and in those with staghorn calculi ... Full text Link to item Cite

Oxalobacter formigenes may reduce the risk of calcium oxalate kidney stones.

Journal article J Am Soc Nephrol · June 2008 Featured Publication Most kidney stones are composed primarily of calcium oxalate. Oxalobacter formigenes is a Gram-negative, anaerobic bacterium that metabolizes oxalate in the intestinal tract and is present in a large proportion of the normal adult population. It was hypoth ... Full text Link to item Cite

Use of the Escape nitinol stone retrieval basket facilitates fragmentation and extraction of ureteral and renal calculi: a pilot study.

Journal article J Endourol · June 2008 Featured Publication BACKGROUND AND PURPOSE: Advances in ureteroscope and stone basket design have catapulted ureteroscopy to the forefront of surgical stone management; however, persistent problems such as stone migration continue to challenge urologists. The Escape nitinol s ... Full text Link to item Cite

Assessment of citrate concentrations in citrus fruit-based juices and beverages: implications for management of hypocitraturic nephrolithiasis.

Journal article J Endourol · June 2008 Featured Publication BACKGROUND AND PURPOSE: Dietary intake of citrate in the form of citrus juices (eg, lemonade, orange juice) will enhance urinary citrate excretion, a valuable benefit for patients with hypocitraturic calcium oxalate nephrolithiasis. While information on ci ... Full text Link to item Cite

Comparison of a novel radially dilating balloon ureteral access sheath to a conventional sheath in the porcine model.

Journal article J Urol · May 2008 Featured Publication PURPOSE: Traditional ureteral access sheaths rely on tapered dilators and the Dotter principle of axial force to gain access into the ureter. We compared the performance of a novel balloon expandable ureteral access sheath using radial dilatation with that ... Full text Link to item Cite

Efficacy of intravesical ropivacaine injection on urinary symptoms following ureteral stenting: a randomized, controlled study.

Journal article J Endourol · March 2008 Featured Publication PURPOSE: Previous studies suggest that intravesical administration of nonsteroidal anti-inflammatory drugs may reduce the troublesome voiding symptoms and pain related to ureteral stenting. The objective of this study was to investigate the effectiveness o ... Full text Link to item Cite

Ureteroscopic management of stones in anomalous kidneys.

Journal article Arch Ital Urol Androl · March 2008 Featured Publication Surgical management of stones in anomalous kidney presents a problem for urologic surgeons. Various minimally invasive management options have been previously reported including shock wave lithotripsy (SWL), percutanteous nephrolithitomy (PNL), as well as ... Link to item Cite

Urolithiasis: not just a 2-legged animal disease.

Journal article J Urol · January 2008 Featured Publication PURPOSE: In this systematic review we summarize information on animal models of stone formation, the similarities of stone formation between humans and nonhuman animals, and the management of naturally occurring stones in animals, particularly dogs and cat ... Full text Link to item Cite

2007 guideline for the management of ureteral calculi.

Journal article J Urol · December 2007 Featured Publication Full text Link to item Cite

Practice patterns of ureteral stenting after routine ureteroscopic stone surgery: a survey of practicing urologists.

Journal article J Endourol · November 2007 Featured Publication BACKGROUND: Controversy exists regarding the need for ureteral stent insertion after routine ureteroscopic stone surgery. We designed a questionnaire to assess and better understand the practice patterns of urologists for stent applications. MATERIALS AND ... Full text Link to item Cite

Shock wave lithotripsy or ureteroscopy for the management of proximal ureteral calculi: an old discussion revisited.

Journal article J Urol · October 2007 Featured Publication PURPOSE: The goal of treating ureteral calculi is to achieve complete stone clearance with minimal patient morbidity. Shock wave lithotripsy and ureteroscopy have become standards of care for ureteral calculi. However, the optimal choice of treatment depen ... Full text Link to item Cite

Subcutaneous bupivacaine infiltration and postoperative pain perception after percutaneous nephrolithotomy.

Journal article J Urol · September 2007 Featured Publication PURPOSE: Recent studies have shown a significant decrease in patient reported pain scores when the nephrostomy tube size is decreased from 22 to 10Fr. We hypothesize that patient reported pain and narcotic use could be further decreased for patients with p ... Full text Link to item Cite

Nephrolithiasis in identical twins: the impact of nature vs nurture.

Journal article BJU Int · September 2007 Featured Publication OBJECTIVE: To assess possible underlying metabolic abnormalities in three sets of monozygotic twins, to evaluate the interplay among the factors of kidney stone formation, a complex multifactorial process influenced by environmental, genetic and anatomical ... Full text Link to item Cite

Holmium laser for stone management.

Journal article World J Urol · June 2007 Featured Publication The efficiency and safety profile of the holmium laser has made this tool a versatile multi-purpose instrument for use in the endoscopic treatment of a wide variety of urologic disorders, in particular urinary calculi. Herein we review holmium laser physic ... Full text Link to item Cite

Effect of medical management on recurrent stone formation following percutaneous nephrolithotomy.

Journal article J Urol · May 2007 Featured Publication PURPOSE: Percutaneous nephrolithotomy is a commonly used procedure for treatment of large or complex renal calculi. In some instances postoperative residual stone fragments are an unavoidable result. Yet to our knowledge no study has examined the impact of ... Full text Link to item Cite

The effect of frequency doubled double pulse Nd:YAG laser fiber proximity to the target stone on transient cavitation and acoustic emission.

Journal article J Urol · April 2007 Featured Publication PURPOSE: Scant information has been published describing the effect of laser fiber distance from the stone target on the mechanism of calculus fragmentation. Using high speed photography and acoustic emission measurements we characterized the impact of las ... Full text Link to item Cite

Forced versus minimal intravenous hydration in the management of acute renal colic: a randomized trial.

Journal article J Endourol · October 2006 Featured Publication BACKGROUND AND PURPOSE: The management of acute renal colic is a problem commonly encountered by both urologists and emergency medicine physicians. The classic approach to managing uncomplicated acute renal colic involves hydration, along with imaging and ... Full text Link to item Cite

Metabolic abnormalities associated with calyceal diverticular stones.

Journal article BJU Int · May 2006 Featured Publication OBJECTIVE: To review the metabolic analyses of patients with calyceal diverticular stones who had surgical treatment of their calculi and to examine the effect of selective medical therapy on stone recurrence, as recent reports suggest that metabolic abnor ... Full text Link to item Cite

Use of Stone Cone minimizes stone migration during percutaneous nephrolithotomy.

Journal article Urology · May 2006 Featured Publication We describe a simple and effective method using the Stone Cone to prevent migration of stone fragments into the ureter during percutaneous nephrolithotomy. This maneuver may reduce the need for antegrade ureteroscopy to remove residual fragments, thereby s ... Full text Link to item Cite

Renal calculi presenting as hyperhidrosis in patient with spinal cord injury.

Journal article Urology · May 2006 Featured Publication Renal calculi in the spinal cord injury population present a diagnostic dilemma for urologists. However, 7% of all patients with spinal cord injury will develop renal calculi. Undiagnosed stone disease can lead to significant morbidity and mortality in thi ... Full text Link to item Cite

Management of lower pole renal calculi: shock wave lithotripsy versus percutaneous nephrolithotomy versus flexible ureteroscopy.

Journal article Urol Res · April 2006 Featured Publication Current ureteroscopic intracorporeal lithotripsy devices and stone retrieval technology allow for the treatment of calculi located throughout the intra-renal collecting system. Difficulty accessing lower pole calculi, especially when the holmium laser fibe ... Full text Link to item Cite