Stuart Alan Grant | Scholars@Duke

Stuart Alan Grant
Professor of Anesthesiology

My research interests include regional anesthesia, acute pain management, and ambulatory anesthesia.
Our regional anesthesia group have particular interest in resident education and ultrasound guided nerve block. We also have an interest in the use of continuous peripheral catheter systems and liposomal drug delivery systems for prolonged post operative analgesia. We also investigate the effects of regional anesthesia on patient outcomes.
My ambulatory anesthesia research interests include post operative recovery with particular reference to fitness to drive and the use of regional anesthetic techniques in day surgery. I also have an interest in total intravenous anesthesia and target controlled infusion drug delivery systems.

Current Appointments & Affiliations

Professor of Anesthesiology, Anesthesiology, Regional, Anesthesiology 2008

Contact Information

2301 Erwin Road, 5691A Hafs Building, Durham, NC 27710
Box 3094 Med Ctr, Durham, NC 27710
grant021@mc.duke.edu (919) 681-6437

Background
Education, Training, & Certifications
- Specialist Registra, Anesthesia, The Victoria Infirmary 1995 - 1998
- M.B.B.Ch., University of Glasgow (Scotland) 1989
Duke Appointment History
- Assistant Professor of Anesthesiology, Anesthesiology, Regional, Anesthesiology 2007 - 2008
- Assistant Professor of Anesthesiology, Anesthesiology, Regional, Anesthesiology 2003 - 2007
- Associate in the Department of Anesthesiology, Anesthesiology, Regional, Anesthesiology 2002 - 2003
- Visiting Associate in the Department of Anesthesiology, Anesthesiology, Ambulatory, Anesthesiology 1999 - 2000
Research
Selected Grants
- Randomized Controlled Trial of SPR Pre-op PNS for TKA awarded by SPR Therapeutics, LLC 2017 - 2019
- Halyard PACMAN awarded by Halyard Health, Inc. 2017 - 2018
- CARA CR845 for abdominal surgery pain awarded by Cara Therapeutics, Inc. 2015 - 2018
- Durect PERSIST awarded by DURECT Corporation 2015 - 2018
- SPR: TKA PREOP awarded by SPR Therapeutics, LLC 2015 - 2018
- A Prospective Case Series In-Clinic Feasibility Study of SPR peripheral nerve stimulation (PNS) therapy for the treatment of pain following total knee arthroplasty (TKA) awarded by SPR Therapeutics, LLC 2015 - 2017
- Human Fresh Tissue Lab - Halyard Health awarded by Halyard Health, Inc. 2016
Publications & Artistic Works
Selected Publications
- Books
  - Grant, SA, and Auyong, DB. Ultrasound Guided Regional Anesthesia. Oxford University Press, September 22, 2016.
  - Grant, SA, and Auyoung, DB. Ultrasound Guided Regional Anesthesia. Oxford University Press, June 7, 2012.
- Academic Articles
  - Kumar, L, Kumar, AH, Grant, SA, and Gadsden, J. "Updates in Enhanced Recovery Pathways for Total Knee Arthroplasty." Anesthesiology Clinics 36, no. 3 (September 2018): 375-386. (Review) Full Text
  - Ilfeld, BM, Ball, ST, Gabriel, RA, Sztain, JF, Monahan, AM, Abramson, WB, Khatibi, B, Said, ET, Parekh, J, Grant, SA, Wongsarnpigoon, A, and Boggs, JW. "A Feasibility Study of Percutaneous Peripheral Nerve Stimulation for the Treatment of Postoperative Pain Following Total Knee Arthroplasty." Neuromodulation : Journal of the International Neuromodulation Society (July 19, 2018). Full Text
  - Kumar, AH, Kim, J, Sadeghi, N, Leversedge, FJ, Moorman, CT, and Grant, SA. "The use of ultrasound imaging for brachial plexus injury assessment following operative clavicle repair." Canadian journal of anaesthesia = Journal canadien d'anesthesie (January 30, 2018). (Letter) Full Text
  - Scott, MJ, McEvoy, MD, Gordon, DB, Grant, SA, Thacker, JKM, Wu, CL, Gan, TJ, Mythen, MG, Shaw, AD, Miller, TE, and Perioperative Quality Initiative (POQI) I Workgroup, . "Correction to: American Society for Enhanced Recovery (ASER) and Perioperative Quality Initiative (POQI) Joint Consensus Statement on Optimal Analgesia within an Enhanced Recovery Pathway for Colorectal Surgery: Part 2-From PACU to the Transition Home." Perioperative Medicine (London, England) 7 (January 2018): 4-null. Full Text Open Access Copy
  - Ilfeld, BM, Grant, SA, Gilmore, CA, Chae, J, Wilson, RD, Wongsarnpigoon, A, and Boggs, JW. "Neurostimulation for Postsurgical Analgesia: A Novel System Enabling Ultrasound-Guided Percutaneous Peripheral Nerve Stimulation." Pain Practice : the Official Journal of World Institute of Pain 17, no. 7 (September 2017): 892-901. Full Text
  - Kumar, A, Sadeghi, N, Wahal, C, Gadsden, J, and Grant, SA. "Quadratus Lumborum Spares Paravertebral Space in Fresh Cadaver Injection." Anesthesia and analgesia 125, no. 2 (August 2017): 708-709. (Letter) Full Text
  - Ilfeld, BM, Gabriel, RA, Saulino, MF, Chae, J, Peckham, PH, Grant, SA, Gilmore, CA, Donohue, MC, deBock, MG, Wongsarnpigoon, A, and Boggs, JW. "Infection Rates of Electrical Leads Used for Percutaneous Neurostimulation of the Peripheral Nervous System." Pain Practice : the Official Journal of World Institute of Pain 17, no. 6 (July 2017): 753-762. (Review) Full Text
  - Bullock, WM, Yalamuri, SM, Gregory, SH, Auyong, DB, and Grant, SA. "Ultrasound-Guided Suprainguinal Fascia Iliaca Technique Provides Benefit as an Analgesic Adjunct for Patients Undergoing Total Hip Arthroplasty." Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine 36, no. 2 (February 2017): 433-438. Full Text
  - Ilfeld, BM, Gilmore, CA, Grant, SA, Bolognesi, MP, Del Gaizo, DJ, Wongsarnpigoon, A, and Boggs, JW. "Ultrasound-guided percutaneous peripheral nerve stimulation for analgesia following total knee arthroplasty: a prospective feasibility study." Journal of Orthopaedic Surgery and Research 12, no. 1 (January 13, 2017): 4-null. Full Text
  - Giattino, CM, Gardner, JE, Sbahi, FM, Roberts, KC, Cooter, M, Moretti, E, Browndyke, JN, Mathew, JP, Woldorff, MG, Berger, M, and MADCO-PC Investigators, . "Intraoperative Frontal Alpha-Band Power Correlates with Preoperative Neurocognitive Function in Older Adults." Frontiers in Systems Neuroscience 11 (January 2017): 24-null. Full Text Open Access Copy
  - Horres, CR, Adam, MA, Sun, Z, Thacker, JK, Moon, RE, Miller, TE, and Grant, SA. "Enhanced recovery protocols for colorectal surgery and postoperative renal function: a retrospective review." Perioperative medicine (London, England) 6 (January 2017): 13-. Full Text Open Access Copy
  - McEvoy, MD, Scott, MJ, Gordon, DB, Grant, SA, Thacker, JKM, Wu, CL, Gan, TJ, Mythen, MG, Shaw, AD, Miller, TE, and Perioperative Quality Initiative (POQI) I Workgroup, . "American Society for Enhanced Recovery (ASER) and Perioperative Quality Initiative (POQI) joint consensus statement on optimal analgesia within an enhanced recovery pathway for colorectal surgery: part 1-from the preoperative period to PACU." Perioperative Medicine (London, England) 6 (January 2017): 8-null. Full Text Open Access Copy
  - Scott, MJ, McEvoy, MD, Gordon, DB, Grant, SA, Thacker, JKM, Wu, CL, Gan, TJ, Mythen, MG, Shaw, AD, Miller, TE, and Perioperative Quality Initiative (POQI) I Workgroup, . "American Society for Enhanced Recovery (ASER) and Perioperative Quality Initiative (POQI) Joint Consensus Statement on Optimal Analgesia within an Enhanced Recovery Pathway for Colorectal Surgery: Part 2-From PACU to the Transition Home." Perioperative Medicine (London, England) 6 (January 2017): 7-null. Full Text Open Access Copy
  - Vora, MU, Nicholas, TA, Kassel, CA, and Grant, SA. "Adductor canal block for knee surgical procedures: review article." Journal of Clinical Anesthesia 35 (December 2016): 295-303. (Review) Full Text
  - Ilfeld, BM, and Grant, SA. "Ultrasound-Guided Percutaneous Peripheral Nerve Stimulation for Postoperative Analgesia: Could Neurostimulation Replace Continuous Peripheral Nerve Blocks?." Regional Anesthesia and Pain Medicine 41, no. 6 (November 2016): 720-722. Full Text
  - Richardson, AB, Bala, A, Wellman, SS, Attarian, DE, Bolognesi, MP, and Grant, SA. "Perioperative Dexamethasone Administration Does Not Increase the Incidence of Postoperative Infection in Total Hip and Knee Arthroplasty: A Retrospective Analysis." The Journal of arthroplasty 31, no. 8 (August 2016): 1784-1787. Full Text
  - Smith, EC, Xixis, KI, Grant, GA, and Grant, SA. "Assessment of obstetric brachial plexus injury with preoperative ultrasound." Muscle & nerve 53, no. 6 (June 2016): 946-950. Full Text
  - Sutton, E, Bullock, WM, Gadsden, J, and Grant, SA. "The "Step-Off" Technique Can Confirm a Successful Peripheral Nerve Block." Regional anesthesia and pain medicine 41, no. 3 (May 2016): 417-. (Letter) Full Text
  - Horres, CR, Adam, MA, Sun, Z, Thacker, JK, Miller, TE, and Grant, SA. "Erratum to: Proceedings of the American Society for Enhanced Recovery/Evidence Based Peri-Operative Medicine 2016 Annual Congress of Enhanced Recovery and Perioperative Medicine: Washington, D.C., USA, 20–22 April 2016." Perioperative Medicine 5 (January 2016).
  - Halawi, MJ, Grant, SA, and Bolognesi, MP. "Multimodal Analgesia for Total Joint Arthroplasty." Orthopedics 38, no. 7 (July 2015): e616-e625. (Review) Full Text
  - Grant, SA, and Smith, EC. "Ultrasound of cervical roots and brachial plexus in neonates." Muscle & nerve 51, no. 4 (April 2015): 626-. (Letter) Full Text
  - Newman, ET, Watters, TS, Lewis, JS, Jennings, JM, Wellman, SS, Attarian, DE, Grant, SA, Green, CL, Vail, TP, and Bolognesi, MP. "Impact of perioperative allogeneic and autologous blood transfusion on acute wound infection following total knee and total hip arthroplasty." The Journal of bone and joint surgery. American volume 96, no. 4 (February 2014): 279-284. Full Text
  - American Society of Anesthesiologists Task Force on Central Venous Access, , Rupp, SM, Apfelbaum, JL, Blitt, C, Caplan, RA, Connis, RT, Domino, KB, Fleisher, LA, Grant, S, Mark, JB, Morray, JP, Nickinovich, DG, and Tung, A. "Practice guidelines for central venous access: a report by the American Society of Anesthesiologists Task Force on Central Venous Access." Anesthesiology 116, no. 3 (March 2012): 539-573. Full Text
  - Auyong, DB, Hostetter, LS, and Grant, SA. "Ultrasound refraction artifact is unlikely a response to duplication of brachial plexus." Regional Anesthesia and Pain Medicine 36, no. 1 (January 2011): 90-91. (Letter) Full Text
  - Rotemberg, V, Palmeri, M, Rosenzweig, S, Grant, S, Macleod, D, and Nightingale, K. "Acoustic radiation force impulse (ARFI) imaging-based needle visualization." Ultrasonic Imaging 33, no. 1 (2011): 1-16.
  - Harrop-Griffiths, W. "'The workman is worthy of his hire' : What is an anaesthetist worth in 2010?." Anaesthesia 65, no. 4 (April 2010): 325-327. Full Text
  - Neal, JM, Brull, R, Chan, VWS, Grant, SA, Horn, J-L, Liu, SS, McCartney, CJL, Narouze, SN, Perlas, A, Salinas, FV, Sites, BD, and Tsui, BC-H. "The ASRA evidence-based medicine assessment of ultrasound-guided regional anesthesia and pain medicine: Executive summary." Regional Anesthesia and Pain Medicine 35, no. 2 Suppl (March 2010): S1-S9. (Review) Full Text
  - Neal, JM, Brull, R, Chan, VWS, Grant, SA, Horn, JL, Liu, SS, McCartney, CJL, Narouze, SN, Perlas, A, Salinas, FV, Sites, BD, and Tsui, BCH. "The ASRA evidence-based medicine assessment of ultrasound-guided regional anesthesia and pain medicine: Executive summary." Regional Anesthesia and Pain Medicine 35, no. 2 Suppl (January 1, 2010).
  - Thornton, PC, Grant, SA, and Breslin, DS. "Adjuncts to local anesthetics in peripheral nerve blockade." International Anesthesiology Clinics 48, no. 4 (2010): 59-70. Full Text
  - Palmeri, ML, Dahl, JJ, MacLeod, DB, Grant, SA, and Nightingale, KR. "On the feasibility of imaging peripheral nerves using acoustic radiation force impulse imaging." Ultrason Imaging 31, no. 3 (July 2009): 172-182. Full Text Link to Item
  - Benonis, J, and Grant, SA. "The Use of Ultrasound in Regional Anesthesia." Advances in Anesthesia 25 (December 6, 2007): 189-204. (Review) Full Text
  - Grant, S. "Continuous nerve blocks: Perineural local anesthetic infusion." (December 1, 2007): 282-284. (Chapter) Full Text
  - Indelli, PF, Grant, SA, Nielsen, K, and Vail, TP. "Regional anesthesia in hip surgery." Clinical Orthopaedics and Related Research 441 (December 2005): 250-255. (Review) Full Text
  - Watson, MW, Mitra, D, McLintock, TC, and Grant, SA. "Continuous versus single-injection lumbar plexus blocks: comparison of the effects on morphine use and early recovery after total knee arthroplasty." Regional Anesthesia and Pain Medicine 30, no. 6 (November 2005): 541-547. Full Text
  - Grant, SA, and Breslin, DS. "Continuous peripheral nerve blockade." Continuing Education in Anaesthesia Critical Care & Pain 5, no. 1 (February 2005): 26-29. Full Text
  - Gerancher, JC, Viscusi, ER, Liguori, GA, McCartney, CJ, Williams, BA, Ilfeld, BM, Grant, SA, Hebl, JR, and Hadzic, A. "Development of a standardized peripheral nerve block procedure note form." Regional Anesthesia and Pain Medicine 30, no. 1 (January 2005): 67-71. Full Text
  - Grant, SA, Breslin, DS, MacLeod, DB, Gleason, D, and Martin, G. "Dexmedetomidine infusion for sedation during fiberoptic intubation: a report of three cases." J Clin Anesth 16, no. 2 (March 2004): 124-126. Full Text Link to Item
  - Grant, SA, Breslin, DS, Martin, G, and Macleod, DB. "Infectious complications." Reg Anesth Pain Med 29, no. 1 (January 2004): 70-. (Letter) Link to Item
  - Macleod, DB, Grant, SA, Martin, G, and Breslin, DS. "Identification of coracoid process for infraclavicular blocks." Reg Anesth Pain Med 28, no. 5 (September 2003): 485-. (Letter) Link to Item
  - Martin, G, Grant, SA, Macleod, DB, Breslin, DS, and Brewer, RP. "Severe phantom leg pain in an amputee after lumbar plexus block." Regional Anesthesia and Pain Medicine 28, no. 5 (September 2003): 475-478. Full Text
  - Grant, SA, Breslin, DS, MacLeod, DB, Demeyts, D, Martin, G, D'Ercole, F, and Hardman, D. "Variability in determination of point of needle insertion in peripheral nerve blocks: a comparison of experienced and inexperienced anaesthetists." Anaesthesia 58, no. 7 (July 2003): 688-692. Link to Item
  - MacLeod, D, Grant, S, Breslin, D, and Martin, G. "Lower limb blocks following general anaesthesia." Anaesthesia 58, no. 6 (June 2003): 612-613. (Letter) Link to Item
  - Breslin, DS, Martin, G, Macleod, DB, D'ercole, F, and Grant, SA. "Central nervous system toxicity following the administration of levobupivacaine for lumbar plexus block: A report of two cases." Regional Anesthesia and Pain Medicine 28, no. 2 (March 2003): 144-147. Full Text
  - Grant, SA. "General anesthesia and simulator driving skills [4]." Canadian Journal of Anesthesia 50, no. 9 (2003): 964--.
  - Grant, SA. "The Holy Grail: long-acting local anaesthetics and liposomes." Best Pract Res Clin Anaesthesiol 16, no. 2 (June 2002): 345-352. (Review) Link to Item
  - Grant, SA, Nielsen, KC, Greengrass, RA, Steele, SM, and Klein, SM. "Continuous peripheral nerve block for ambulatory surgery." Regional Anesthesia and Pain Medicine 26, no. 3 (May 2001): 209-214. Full Text
  - Klein, SM, Greengrass, RA, Grant, SA, Higgins, LD, Nielsen, KC, and Steele, SM. "Ambulatory surgery for multi-ligament knee reconstruction with continuous dual catheter peripheral nerve blockade." Can J Anaesth 48, no. 4 (April 2001): 375-378. Link to Item
  - Galley, HF, Cras, AEL, Yassen, K, Grant, S, and Webster, NR. "Circulating tetrahydrobiopterin concentrations in patients with septic shock." British Journal of Anaesthesia 86, no. 4 (2001): 578-580. Full Text
  - Klein, SM, Grant, SA, Greengrass, RA, Nielsen, KC, Speer, KP, White, W, Warner, DS, and Steele, SM. "Interscalene brachial plexus block with a continuous catheter insertion system and a disposable infusion pump." Anesthesia and Analgesia 91, no. 6 (December 2000): 1473-1478. Full Text
  - Grant, SA, Millar, K, and Kenny, GN. "Blood alcohol concentration and psychomotor effects." Br J Anaesth 85, no. 3 (September 2000): 401-406. Link to Item
  - Grant, SA, Murdoch, J, Millar, K, and Kenny, GN. "Blood propofol concentration and psychomotor effects on driving skills." British Journal of Anaesthesia 85, no. 3 (September 2000): 396-400. Full Text
  - Grant, SA, Nielsen, KC, Greengrass, RA, Steele, SM, and Klein, SM. "Continuous peripheral nerve block for ambulatory surgery." ANESTHESIOLOGY 93, no. 3A (September 2000): U123-U123. Link to Item
  - Klein, SM, Grant, SA, Greengrass, RA, Nielsen, KC, and Steele, SM. "Continuous ambulatory interscalene block with a new catheter insertion system and a infusion pump." ANESTHESIOLOGY 93, no. 3A (September 2000): U196-U196. Link to Item
  - Klein, SM, Steele, SM, Grant, SA, Nielsen, KC, and Greengrass, RA. "Paravertebral somatic nerve block versus local infiltration for outpatient inguinal herniorrhaphy." ANESTHESIOLOGY 93, no. 3A (September 2000): U200-U200. Link to Item
  - Klein, SM, Greengrass, RA, Steele, SM, Grant, SA, and Nunley, JA. "Ambulatory Continuous Perineural Infusion: Are We Ready?." Anesthesiology 93, no. 2 (August 2000): 582-582. Full Text
  - Murdoch, JA, Grant, SA, and Kenny, GN. "Safety of patient-maintained propofol sedation using a target-controlled system in healthy volunteers." Br J Anaesth 85, no. 2 (August 2000): 299-301. Link to Item
  - Woods, AW, Grant, S, and Alexander, R. "Remifentanil and intubating conditions (multiple letters)." Anaesthesia 55, no. 5 (May 29, 2000): 516-518. (Letter)
  - Woods, AW, and Grant, S. "Remifentanil and intubating conditions." Anaesthesia 55, no. 5 (May 2000): 516-518. (Letter) Full Text
  - Chelly, JE, Greger, J, Gebhard, R, Klein, SM, Greengrass, RA, Steele, SM, Grant, SA, and Nunley, JA. "Ambulatory continuous perineural infusion: Are we ready? [2] (multiple letters)." Anesthesiology 93, no. 2 (2000): 581-582.
  - Woods, A, Grant, S, and Davidson, A. "Duration of apnoea with two different intubating doses of remifentanil." European Journal of Anaesthesiology 16, no. 9 (September 1999): 634-637. Full Text
  - Guiraud, M, and Chassard, D. "Intubating conditions after propofol and remifentanil." British Journal of Anaesthesia 82, no. 4 (April 1999): 649-650. (Letter) Full Text
  - Woods, AW, Grant, S, Harten, J, Noble, JS, and Davidson, JA. "Tracheal intubating conditions after induction with propofol, remifentanil and lignocaine." European Journal of Anaesthesiology 15, no. 6 (November 1998): 714-718.
  - Grant, S, Noble, S, Woods, A, Murdoch, J, and Davidson, A. "Assessment of intubating conditions in adults after induction with propofol and varying doses of remifentanil." British Journal of Anaesthesia 81, no. 4 (October 1998): 540-543. Full Text
  - Nolan, AM, Reid, J, and Grant, S. "The effects of halothane and nitrous oxide on the pharmacokinetics of propofol in dogs." Journal of Veterinary Pharmacology and Therapeutics 16, no. 3 (1993): 335-342.
- Book Sections
  - Barton, J, and Grant, SA. "Outcome studies and infection control in regional anesthesia." In Essentials of Regional Anesthesia, 741-777. January 1, 2012. Full Text
- Conference Papers
  - Grant, SA, Van de Ven, TJ, Grichnik, K, Scouras, M, Gadsden, J, Martin, G, and Mathew, JP. "A Dose Finding Study of the Ideal Analgesic Dose of Intravenous Dexamethasone for Total Knee Arthroplasty." Annual Meeting and International Science Symposium of the International-Anesthesia-Research-Society. Washington, DC. May 6, 2017 - May 9, 2017.: LIPPINCOTT WILLIAMS & WILKINS, May 1, 2017. Link to Item
  - Grant, SA, Wahal, C, Kumar, A, Sadeghi, N, Dooley, J, Horazeck, C, and Gadsden, J. "A Radiographic Cadaveric Comparison of Transmuscular Quadratus Lumborum Block and Lower Thoracic Paravertebral Block." Annual Meeting and International Science Symposium of the International-Anesthesia-Research-Society. Washington, DC. May 6, 2017 - May 9, 2017.: LIPPINCOTT WILLIAMS & WILKINS, May 1, 2017. Link to Item
Teaching & Mentoring
Recent Courses
- ANESTH 220C: Clinical Anesthesiology 2019

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Education, Training, & Certifications

Duke Appointment History

Selected Grants

Selected Publications

Books

Academic Articles

Book Sections

Conference Papers

Recent Courses