Skip to main content

Gregory L Sahlem

Associate Professor in Psychiatry and Behavioral Sciences
Psychiatry & Behavioral Sciences, Behavioral Medicine & Neurosciences

Overview


Dr. Sahlem is an Associate Professor in the Department of Psychiatry and Behavioral Sciences at Duke University. He is board-certified in general psychiatry and addiction medicine, fellowship-trained in interventional psychiatry, and has advanced training in the treatment of addictive, mood, and sleep disorders. He is an active clinician and enthusiastic educator. He is additionally interested in the translational development of new treatments for mood and substance use disorders using circuit-based approaches.

Current Appointments & Affiliations


Associate Professor in Psychiatry and Behavioral Sciences · 2025 - Present Psychiatry & Behavioral Sciences, Behavioral Medicine & Neurosciences, Psychiatry & Behavioral Sciences

In the News


Published August 19, 2025
Duke Researchers Hope to Rewire the Cannabis-Addicted Brain

View All News

Recent Publications


Exploring the Utility of a Functional Magnetic Resonance Imaging Cannabis Cue-Reactivity Paradigm in Treatment-Seeking Adults With Cannabis Use Disorder.

Journal Article Biol Psychiatry Cogn Neurosci Neuroimaging · May 2025 BACKGROUND: Functional magnetic resonance imaging studies examining cue reactivity in cannabis use disorder (CUD) either have had small sample sizes or have involved non-treatment-seeking participants. As a secondary analysis, we administered a functional ... Full text Link to item Cite

Sex differences in normative modeling of cortical thickness in cannabis use disorder

Journal Article Drug and Alcohol Dependence Reports · March 1, 2025 Cannabis use disorder (CUD) is associated with sexually dimorphic behavioral and neurobiological effects, but sex differences in a broader sampling of brain structures in CUD assessed relative to normative reference values have not been examined. Here, we ... Full text Cite

A Secondary Analysis Suggests That Repetitive Transcranial Magnetic Stimulation Applied to the Left Dorsolateral Prefrontal Cortex Reduces Cue-Induced-Craving in Treatment Seeking Participants with Cannabis Use Disorder.

Journal Article medRxiv · January 17, 2025 BACKGROUND: Studies across multiple addictions have suggested that repetitive transcranial magnetic stimulation (rTMS) applied to the left dorsolateral prefrontal cortex (L-DLPFC) reduces cue-induced-craving (CIC), however there are no studies in treatment ... Full text Link to item Cite
View All Publications

Recent Grants


The Development and Validation of Neural Targets in Opioid Use Disorder for Use Across Addictions

ResearchPrincipal Investigator · Awarded by Wellcome Leap · 2024 - 2027

View All Grants

Education, Training & Certifications


University at Buffalo, Jacobs School of Medicine and Biomedical Sciences · 2010 M.D.