Overview
Dr. Sahlem is an Associate Professor in the Department of Psychiatry and Behavioral Sciences at Duke University. He is board-certified in general psychiatry and addiction medicine, fellowship-trained in interventional psychiatry, and has advanced training in the treatment of addictive, mood, and sleep disorders. He is an active clinician and enthusiastic educator. He is additionally interested in the translational development of new treatments for mood and substance use disorders using circuit-based approaches.
Current Appointments & Affiliations
Associate Professor in Psychiatry and Behavioral Sciences
·
2025 - Present
Psychiatry & Behavioral Sciences, Behavioral Medicine & Neurosciences,
Psychiatry & Behavioral Sciences
Recent Publications
Stanford neuromodulation therapy for treatment-resistant depression: a randomized controlled trial confirming efficacy, and an EEG study providing insight into mechanism of action and a potentially predictive biomarker of efficacy.
Journal Article World Psychiatry · February 2026 Stanford neuromodulation therapy (SNT) is a rapid-acting, high-dose, intermittent theta-burst stimulation protocol. Although it has previously demonstrated efficacy for treatment-resistant depression (TRD) in a randomized controlled trial (RCT), replicatio ... Full text Link to item CiteA protocol for the development of a core outcome set for adults with depression.
Journal Article J Clin Epidemiol · December 29, 2025 BACKGROUND AND OBJECTIVE: Heterogeneous outcome measurement limits the comparison and combination of results from randomized controlled trials and observational studies aimed at evaluating therapeutic interventions for depression. We report here the protoc ... Full text Link to item CiteToward Inclusive, Evidence-Based rTMS Care for Patients With Co-Occurring Substance Use Disorders.
Journal Article Am J Psychiatry · December 1, 2025 Full text Link to item CiteRecent Grants
A Phase-3 Trial of Repetitive Transcranial Magnetic Stimulation for Cannabis Use Disorder (rTMS)
ResearchPrincipal Investigator · Awarded by Oregon Health & Science University · 2025 - 2032The Development and Validation of Neural Targets in Opioid Use Disorder for Use Across Addictions
ResearchPrincipal Investigator · Awarded by Wellcome Leap · 2024 - 2027View All Grants
Education, Training & Certifications
University at Buffalo, Jacobs School of Medicine and Biomedical Sciences ·
2010
M.D.