Journal ArticleMed Dosim · 2009
Adjuvant radiotherapy for locally advanced prostate cancer improves biochemical and clinical disease-free survival. While comparisons in intact prostate cancer show a benefit for intensity modulated radiation therapy (IMRT) over 3D conformal planning, this ...
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Journal ArticleInt J Radiat Oncol Biol Phys · October 1, 2008
PURPOSE: To provide a synopsis of the history of the association of radiation oncologists in the United States, currently known as the American Society for Therapeutic Radiology and Oncology (ASTRO), with the occasion of the 50th anniversary of the organiz ...
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Journal ArticleJournal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer · September 2006
BackgroundMultidisciplinary clinics have been recommended for the evaluation of patients with lung cancer. Evidence to support this recommendation, however, is limited. A single-center, retrospective review of lung cancer patients at a Veterans Af ...
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Journal ArticleInt J Radiat Oncol Biol Phys · June 1, 2006
PURPOSE: The aim of this retrospective review of patients with gynecologic malignancies treated with external beam radiotherapy (EBRT) and interstitial brachytherapy was to determine the rate of Grade > or =2 rectovaginal fistula and Grade > or =4 small bo ...
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Journal ArticleJ Am Geriatr Soc · September 2005
OBJECTIVES: To describe the long-term effects of oral health problems on quality of life (QoL), functional status, pain, and general health in older male cancer patients. DESIGN: Secondary analysis of a prospective observational study. SETTING: Community d ...
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Journal ArticleCurr Treat Options Oncol · April 2004
One of the most significant developments in recent decades in the management of malignant diseases is the recognition that surgery, radiation, and chemotherapy have limited curative potential. Along with this recognition has come the realization that altho ...
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Journal ArticleChest · 2004
Study objective: To identify factors associated with a misclassification of the true disease stage by comparing the differences between the clinical and pathologic stage of patients with early-stage non-small cell lung cancer (NSCLC). Design: A prospective ...
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Journal ArticleInt J Radiat Oncol Biol Phys · May 1, 2002
PURPOSE: To characterize the severity and time course of rectal toxicity following transperineal prostate brachytherapy using prospectively recorded data, and to determine factors associated with toxicity. METHODS AND MATERIALS: One hundred thirty-four pat ...
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Journal ArticleJ Clin Oncol · February 1, 2002
PURPOSE: Comprehensive geriatric assessment (CGA) has aided the medical community greatly in understanding the quality-of-life issues and functional needs of older patients. With its professional team assessment approach, however, CGA may be time consuming ...
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Journal ArticleInt J Radiat Oncol Biol Phys · July 15, 2001
PURPOSE: To examine the acute urinary toxicity following transperineal prostate implant using a modified Quimby loading method with regard to time course, severity, and factors that may be associated with a higher incidence of morbidity. METHODS AND MATERI ...
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Journal ArticleInt J Radiat Oncol Biol Phys · November 1, 2000
PURPOSE: To determine if patients with carcinoma of the vulva, with N2/N3 lymph nodes, could undergo resection of the lymph nodes and primary tumor following preoperative chemo-radiation. METHODS AND MATERILAS: Fifty-two patients were entered in the study, ...
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Journal ArticleRadiother Oncol · July 2000
PURPOSE: To describe external, internal and common iliac dose rates estimated with 3D-computed tomography (CT) based dose calculations in tandem and ovoid brachytherapy. MATERIALS AND METHODS: Thirty patients with carcinoma of the uterine cervix received l ...
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Journal ArticleClin Cancer Res · December 1999
We report the use of an exponential model for capturing the dynamics of serial measurements of prostate-specific antigen (PSA) made just before and after definitive radiation therapy of localized prostate cancer. Our study patients consisted of 164 men tre ...
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Journal ArticleClin Cancer Res · September 1999
In this report, we use new patient data to test three popular models developed to predict the outcome of definitive radiation therapy. The data come from 240 men with localized prostate cancer and who were treated with definitive radiation therapy at a com ...
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Journal ArticleInt J Radiat Oncol Biol Phys · August 1, 1998
PURPOSE: To determine the feasibility of using preoperative chemoradiotherapy to avert the need for more radical surgery for patients with T3 primary tumors, or the need for pelvic exenteration for patients with T4 primary tumors, not amenable to resection ...
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Journal ArticleProstate Cancer Prostatic Dis · June 1998
Objective: To compare results of treatment of adenocardinoma of the prostate using Standard (2D) vs Conformal (3D) treatment planning. Methods: The records of all patients with adenocarcinoma of the prostate treated curatively with radiation therapy alone ...
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Journal ArticleRadiat Oncol Investig · 1998
The purpose of this work is to compare bladder and rectal dose rates in brachytherapy for carcinoma of the cervix using two different dosimetry systems: traditional orthogonal radiograph-based dosimetry vs. computed axial tomography tandem and ovoids (CATT ...
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Journal ArticleInt J Radiat Oncol Biol Phys · January 15, 1997
PURPOSE: Intracavitary dose prescription for cancer of the uterine cervix has been based on the use of plane orthogonal films. Computed tomography (CT) and magnetic resonance imaging can provide three-dimensional (3D) anatomic information with which more s ...
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Journal ArticleInt J Radiat Oncol Biol Phys · July 30, 1995
PURPOSE: A review of the Patterns of Care Studies Process Survey data on carcinoma of the cervix conducted on patients in 1978, 1983, and 1988-89 was carried out to identify changes or trends in the demographics, evaluation, and treatment that might have o ...
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Journal ArticleInt J Radiat Oncol Biol Phys · May 15, 1995
PURPOSE: To determine the efficacy of radiotherapy (RT) in patients with an isolated elevation of prostate specific antigen (PSA) after radical prostatectomy (RP). METHODS AND MATERIALS: Between November 1987 and May 1993, 53 patients with adenocarcinoma o ...
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Journal ArticleInt J Oncol · October 1993
The records of 180 patients definitively irradiated for newly diagnosed adenocarcinoma of the prostate between 1970 and 1988 at Duke University Medical Center (107 patients from 1970-1983) and Moore Regional Hospital (73 patients from 1981-1988) were revie ...
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Journal ArticleJ Clin Oncol · October 1992
PURPOSE: Recent reports suggest an increasing incidence of CNS metastases in patients with ovarian cancer. We reviewed our experience in the management of brain metastases from ovarian carcinoma and merged our results with those of several other series rep ...
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Journal ArticleCancer · June 1, 1992
Patients undergoing x-ray therapy to the pelvis have intestinal symptoms proportional to the volume treated and the dose delivered. WR-2721, S-2 (3-aminopropylaminoethyl) phosphorothioic acid, is an organic thiophosphate compound that selectively protects ...
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Journal ArticleCancer · April 15, 1992
The 1973 and 1978 national surveys conducted by the Patterns of Care Study (PCS) for squamous cell cancer of the uterine cervix were combined to analyze factors associated with complications after radiation therapy (RT). Overall, 1558 patients were reviewe ...
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Journal ArticleInt J Radiat Oncol Biol Phys · 1992
From 1984-1990, 143 patients with squamous cell or adenocarcinoma of the esophagus were enrolled in a Phase I/II study of neoadjuvant chemotherapy followed by concurrent chemotherapy plus radiotherapy with or without subsequent esophagectomy. Patients rece ...
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Journal ArticleRadiother Oncol · October 1991
252 evaluable patients were treated in the Centre Claudius Regaud from January 1974 to December 1983 for stage Ib, IIa or proximal IIb carcinoma of the uterine cervix. This retrospective analysis compares results obtained either by radio-surgical combinati ...
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Journal ArticleInt J Radiat Oncol Biol Phys · September 1991
A plastic intracavitary applicator system for the treatment of cancer of the uterine cervix is described. This applicator has a minicolpostat and a mechanism for affixing the tandem to the colpostats. Traditional afterloading refers only to the radioactive ...
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Journal ArticleInt J Radiat Oncol Biol Phys · January 1991
Patterns of Care Study (PCS) conducted the second survey of carcinoma of the cervix in 1978. The data of this survey are derived from 565 patient questionnaires completed from 120 randomly selected facilities. Through these surveys PCS has set out to estab ...
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Journal ArticleInt J Radiat Oncol Biol Phys · September 1990
A technique is described for the design and construction of customized templates for transperineal implants and interstitial hyperthermia of pelvic malignancies. The design of the template and the distribution of the transperineal Iridium-192 seed ribbons ...
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Journal ArticleGynecol Oncol · June 1990
From 1971 through 1984, 320 women underwent radical hysterectomy as primary therapy of stage IB and IIA cervical cancer. Two hundred forty-eight patients (78%) were treated with surgery alone and 72 patients (22%) received adjuvant postoperative external-b ...
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Journal ArticleInt J Radiat Oncol Biol Phys · January 1989
From April 1969 through December 1980, 527 patients with epidermoid carcinoma of the cervix received radical radiation therapy at North Carolina Memorial Hospital (NCMH). The treatment was designed to deliver a combined dose (external beam plus intracavita ...
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Journal ArticleCancer · November 1, 1987
From April of 1969 through December of 1980, 197 patients with Stage IB, invasive, epidermoid carcinoma of the cervix received radical radiation therapy. The treatment consisted of external beam and intracavitary therapy designed to deliver 7000 to 8000 ra ...
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Journal ArticleCancer · January 1, 1986
From April 1969 through December 1980, 203 patients with Stage III epidermoid carcinoma of the cervix were treated with radiation therapy with curative intent. The disease-free survival at 2, 5, and 10 years was 50%, 33%, and 27%, respectively. The surviva ...
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Journal ArticleCancer · March 1, 1985
From April 1969 through December 1980, 251 patients with invasive, epidermoid carcinoma of the cervix received radical radiation therapy consisting of a combination of external beam and intracavitary therapy designed to deliver 7000 to 8000 rad to Point A ...
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Journal ArticleAmerican Journal of Obstetrics and Gynecology · 1984
The management of the patient with advanced gynecologic malignancies presents multiple problems for the gynecologic and radiation oncologists involved in their care. When palliative management only is indicated, conventional treatment protocols occupy a si ...
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Journal ArticleInternational Journal of Radiation Oncology, Biology, Physics · 1983
An analysis has been made of 101 patients treated with radiation therapy for epidermoid carcinoma of the cervix Stage IB (FIGO) from January 1970 through December 1976. The patients were treated with a combination of intracavitary therapy and external beam ...
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Journal ArticleObstetrics and Gynecology · 1975
88 Cases of Stage I and Stage II carcinoma of the cervix treated with radiotherapy between April 1969 and July 1971 are reviewed. The question of whether the radiation time dose fraction relationship can be applied to the combination of external beam and i ...
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Journal ArticleNorth Carolina Medical Journal · 1973
The therapeutic value of irradiation in leukemia is well recognized. Irradiation is used in a variety of ways to palliate symptoms as well as, in rare instances, with the intent of eradicating this disease. Of importance also is the leukemic potential of i ...
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