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Gustavo Santos Montana

Professor Emeritus of Radiation Oncology
Radiation Oncology
Box 3085 Med Ctr, Durham, NC 27710
1530 Hosp South, Durham, NC 27710

Selected Publications


A 35-year History of Radiation Therapy Utilization Across the United States

Conference International Journal of Radiation Oncology*Biology*Physics · November 2012 Full text Cite

Dosimetric and radiobiologic comparison of 3D conformal versus intensity modulated planning techniques for prostate bed radiotherapy.

Journal Article Med Dosim · 2009 Adjuvant radiotherapy for locally advanced prostate cancer improves biochemical and clinical disease-free survival. While comparisons in intact prostate cancer show a benefit for intensity modulated radiation therapy (IMRT) over 3D conformal planning, this ... Full text Link to item Cite

Synopsis of history of American Society for Therapeutic Radiology and Oncology 1958-2008.

Journal Article Int J Radiat Oncol Biol Phys · October 1, 2008 PURPOSE: To provide a synopsis of the history of the association of radiation oncologists in the United States, currently known as the American Society for Therapeutic Radiology and Oncology (ASTRO), with the occasion of the 50th anniversary of the organiz ... Full text Link to item Cite

Adult cancer pain.

Journal Article J Natl Compr Canc Netw · September 2007 Link to item Cite

Impact of a multidisciplinary thoracic oncology clinic on the timeliness of care.

Journal Article Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer · September 2006 BackgroundMultidisciplinary clinics have been recommended for the evaluation of patients with lung cancer. Evidence to support this recommendation, however, is limited. A single-center, retrospective review of lung cancer patients at a Veterans Af ... Full text Cite

Predictors of severe gastrointestinal toxicity after external beam radiotherapy and interstitial brachytherapy for advanced or recurrent gynecologic malignancies.

Journal Article Int J Radiat Oncol Biol Phys · June 1, 2006 PURPOSE: The aim of this retrospective review of patients with gynecologic malignancies treated with external beam radiotherapy (EBRT) and interstitial brachytherapy was to determine the rate of Grade > or =2 rectovaginal fistula and Grade > or =4 small bo ... Full text Link to item Cite

Historical Review of the Treatment of Carcinoma of the Cervix: the Point of Point A

Conference International Journal of Radiation Oncology*Biology*Physics · October 2005 Full text Cite

The association between oral health and general health and quality of life in older male cancer patients.

Journal Article J Am Geriatr Soc · September 2005 OBJECTIVES: To describe the long-term effects of oral health problems on quality of life (QoL), functional status, pain, and general health in older male cancer patients. DESIGN: Secondary analysis of a prospective observational study. SETTING: Community d ... Full text Link to item Cite

Adjuvant and salvage radiotherapy following radical prostatectomy

Conference International Journal of Radiation OncologyBiologyPhysics · September 2004 Full text Cite

Carcinoma of the vulva: combined modality treatment.

Journal Article Curr Treat Options Oncol · April 2004 One of the most significant developments in recent decades in the management of malignant diseases is the recognition that surgery, radiation, and chemotherapy have limited curative potential. Along with this recognition has come the realization that altho ... Full text Link to item Cite

Location and upstaging for early-stage non-small cell lung cancer

Journal Article Chest · 2004 Study objective: To identify factors associated with a misclassification of the true disease stage by comparing the differences between the clinical and pathologic stage of patients with early-stage non-small cell lung cancer (NSCLC). Design: A prospective ... Full text Cite

Gastrointestinal toxicity of transperineal interstitial prostate brachytherapy.

Journal Article Int J Radiat Oncol Biol Phys · May 1, 2002 PURPOSE: To characterize the severity and time course of rectal toxicity following transperineal prostate brachytherapy using prospectively recorded data, and to determine factors associated with toxicity. METHODS AND MATERIALS: One hundred thirty-four pat ... Full text Link to item Cite

Comprehensive assessment of the elderly cancer patient: the feasibility of self-report methodology.

Journal Article J Clin Oncol · February 1, 2002 PURPOSE: Comprehensive geriatric assessment (CGA) has aided the medical community greatly in understanding the quality-of-life issues and functional needs of older patients. With its professional team assessment approach, however, CGA may be time consuming ... Full text Link to item Cite

Acute urinary toxicity following transperineal prostate brachytherapy using a modified Quimby loading method.

Journal Article Int J Radiat Oncol Biol Phys · July 15, 2001 PURPOSE: To examine the acute urinary toxicity following transperineal prostate implant using a modified Quimby loading method with regard to time course, severity, and factors that may be associated with a higher incidence of morbidity. METHODS AND MATERI ... Full text Link to item Cite

Preoperative chemo-radiation for carcinoma of the vulva with N2/N3 nodes: a gynecologic oncology group study.

Journal Article Int J Radiat Oncol Biol Phys · November 1, 2000 PURPOSE: To determine if patients with carcinoma of the vulva, with N2/N3 lymph nodes, could undergo resection of the lymph nodes and primary tumor following preoperative chemo-radiation. METHODS AND MATERILAS: Fifty-two patients were entered in the study, ... Full text Link to item Cite

Carcinoma of the uterine cervix: a 3D - CT analysis of dose to the internal, external and common iliac nodes in tandem and ovoid applications.

Journal Article Radiother Oncol · July 2000 PURPOSE: To describe external, internal and common iliac dose rates estimated with 3D-computed tomography (CT) based dose calculations in tandem and ovoid brachytherapy. MATERIALS AND METHODS: Thirty patients with carcinoma of the uterine cervix received l ... Full text Link to item Cite

The dynamics of prostate-specific antigen after definitive radiation therapy for prostate cancer.

Journal Article Clin Cancer Res · December 1999 We report the use of an exponential model for capturing the dynamics of serial measurements of prostate-specific antigen (PSA) made just before and after definitive radiation therapy of localized prostate cancer. Our study patients consisted of 164 men tre ... Link to item Cite

Predicting tumor failure in prostate carcinoma after definitive radiation therapy: limitations of models based on prostate-specific antigen, clinical stage, and Gleason score.

Journal Article Clin Cancer Res · September 1999 In this report, we use new patient data to test three popular models developed to predict the outcome of definitive radiation therapy. The data come from 240 men with localized prostate cancer and who were treated with definitive radiation therapy at a com ... Link to item Cite

Preoperative chemoradiation for advanced vulvar cancer: a phase II study of the Gynecologic Oncology Group.

Journal Article Int J Radiat Oncol Biol Phys · August 1, 1998 PURPOSE: To determine the feasibility of using preoperative chemoradiotherapy to avert the need for more radical surgery for patients with T3 primary tumors, or the need for pelvic exenteration for patients with T4 primary tumors, not amenable to resection ... Full text Link to item Cite

Standard vs conformal radiation therapy for adenocarcinoma of the prostate: no difference.

Journal Article Prostate Cancer Prostatic Dis · June 1998 Objective: To compare results of treatment of adenocardinoma of the prostate using Standard (2D) vs Conformal (3D) treatment planning. Methods: The records of all patients with adenocarcinoma of the prostate treated curatively with radiation therapy alone ... Full text Link to item Cite

Computed axial tomography tandem and ovoids (CATTO) dosimetry: three-dimensional assessment of bladder and rectal doses.

Journal Article Radiat Oncol Investig · 1998 The purpose of this work is to compare bladder and rectal dose rates in brachytherapy for carcinoma of the cervix using two different dosimetry systems: traditional orthogonal radiograph-based dosimetry vs. computed axial tomography tandem and ovoids (CATT ... Full text Link to item Cite

Three-dimensional applicator system for carcinoma of the uterine cervix.

Journal Article Int J Radiat Oncol Biol Phys · January 15, 1997 PURPOSE: Intracavitary dose prescription for cancer of the uterine cervix has been based on the use of plane orthogonal films. Computed tomography (CT) and magnetic resonance imaging can provide three-dimensional (3D) anatomic information with which more s ... Full text Link to item Cite

Carcinoma of the cervix: patterns of care studies: review of 1978, 1983, and 1988-1989 surveys.

Journal Article Int J Radiat Oncol Biol Phys · July 30, 1995 PURPOSE: A review of the Patterns of Care Studies Process Survey data on carcinoma of the cervix conducted on patients in 1978, 1983, and 1988-89 was carried out to identify changes or trends in the demographics, evaluation, and treatment that might have o ... Full text Link to item Cite

In response to Deore et al.

Journal Article International Journal of Radiation Oncology Biology Physics · May 15, 1995 Full text Cite

The efficacy of postprostatectomy radiotherapy in patients with an isolated elevation of serum prostate-specific antigen.

Journal Article Int J Radiat Oncol Biol Phys · May 15, 1995 PURPOSE: To determine the efficacy of radiotherapy (RT) in patients with an isolated elevation of prostate specific antigen (PSA) after radical prostatectomy (RP). METHODS AND MATERIALS: Between November 1987 and May 1993, 53 patients with adenocarcinoma o ... Full text Link to item Cite

Five dosimetric considerations in perineal templates: Regarding Kavanagh et al., IJROBP 30:508; 1994 [5]

Journal Article International Journal of Radiation Oncology Biology Physics · 1995 Full text Cite

The lack of impact of treatment time on the outcome of definitive radiotherapy for carcinoma of the prostate.

Journal Article Int J Oncol · October 1993 The records of 180 patients definitively irradiated for newly diagnosed adenocarcinoma of the prostate between 1970 and 1988 at Duke University Medical Center (107 patients from 1970-1983) and Moore Regional Hospital (73 patients from 1981-1988) were revie ... Full text Link to item Cite

Improved palliation of cerebral metastases in epithelial ovarian cancer using a combined modality approach including radiation therapy, chemotherapy, and surgery.

Journal Article J Clin Oncol · October 1992 PURPOSE: Recent reports suggest an increasing incidence of CNS metastases in patients with ovarian cancer. We reviewed our experience in the management of brain metastases from ovarian carcinoma and merged our results with those of several other series rep ... Full text Link to item Cite

Topical application of WR-2721 to prevent radiation-induced proctosigmoiditis. A phase I/II trial.

Journal Article Cancer · June 1, 1992 Patients undergoing x-ray therapy to the pelvis have intestinal symptoms proportional to the volume treated and the dose delivered. WR-2721, S-2 (3-aminopropylaminoethyl) phosphorothioic acid, is an organic thiophosphate compound that selectively protects ... Full text Link to item Cite

Influence of age, prior abdominal surgery, fraction size, and dose on complications after radiation therapy for squamous cell cancer of the uterine cervix. A patterns of care study.

Journal Article Cancer · April 15, 1992 The 1973 and 1978 national surveys conducted by the Patterns of Care Study (PCS) for squamous cell cancer of the uterine cervix were combined to analyze factors associated with complications after radiation therapy (RT). Overall, 1558 patients were reviewe ... Full text Link to item Cite

Patterns of failure following combined modality therapy for esophageal cancer, 1984-1990.

Journal Article Int J Radiat Oncol Biol Phys · 1992 From 1984-1990, 143 patients with squamous cell or adenocarcinoma of the esophagus were enrolled in a Phase I/II study of neoadjuvant chemotherapy followed by concurrent chemotherapy plus radiotherapy with or without subsequent esophagectomy. Patients rece ... Full text Link to item Cite

Non-randomized comparative study of irradiation alone or in combination with surgery in stage Ib, IIa and "proximal" IIb carcinoma of the cervix.

Journal Article Radiother Oncol · October 1991 252 evaluable patients were treated in the Centre Claudius Regaud from January 1974 to December 1983 for stage Ib, IIa or proximal IIb carcinoma of the uterine cervix. This retrospective analysis compares results obtained either by radio-surgical combinati ... Full text Link to item Cite

Design of a plastic minicolpostat applicator with shields.

Journal Article Int J Radiat Oncol Biol Phys · September 1991 A plastic intracavitary applicator system for the treatment of cancer of the uterine cervix is described. This applicator has a minicolpostat and a mechanism for affixing the tandem to the colpostats. Traditional afterloading refers only to the radioactive ... Full text Link to item Cite

Patterns and sites of failure in cervix cancer treated in the U.S.A. in 1978.

Journal Article Int J Radiat Oncol Biol Phys · January 1991 Patterns of Care Study (PCS) conducted the second survey of carcinoma of the cervix in 1978. The data of this survey are derived from 565 patient questionnaires completed from 120 randomly selected facilities. Through these surveys PCS has set out to estab ... Full text Link to item Cite

Transperineal templates for brachytherapy treatment of pelvic malignancies--a comparison of standard and customized templates.

Journal Article Int J Radiat Oncol Biol Phys · September 1990 A technique is described for the design and construction of customized templates for transperineal implants and interstitial hyperthermia of pelvic malignancies. The design of the template and the distribution of the transperineal Iridium-192 seed ribbons ... Full text Link to item Cite

Adjuvant radiotherapy following radical hysterectomy for patients with stage IB and IIA cervical cancer.

Journal Article Gynecol Oncol · June 1990 From 1971 through 1984, 320 women underwent radical hysterectomy as primary therapy of stage IB and IIA cervical cancer. Two hundred forty-eight patients (78%) were treated with surgery alone and 72 patients (22%) received adjuvant postoperative external-b ... Full text Link to item Cite

Carcinoma of the cervix: analysis of bladder and rectal radiation dose and complications.

Journal Article Int J Radiat Oncol Biol Phys · January 1989 From April 1969 through December 1980, 527 patients with epidermoid carcinoma of the cervix received radical radiation therapy at North Carolina Memorial Hospital (NCMH). The treatment was designed to deliver a combined dose (external beam plus intracavita ... Full text Link to item Cite

Analysis of results of radiation therapy for stage IB carcinoma of the cervix.

Journal Article Cancer · November 1, 1987 From April of 1969 through December of 1980, 197 patients with Stage IB, invasive, epidermoid carcinoma of the cervix received radical radiation therapy. The treatment consisted of external beam and intracavitary therapy designed to deliver 7000 to 8000 ra ... Full text Link to item Cite

Carcinoma of the cervix, stage III. Results of radiation therapy.

Journal Article Cancer · January 1, 1986 From April 1969 through December 1980, 203 patients with Stage III epidermoid carcinoma of the cervix were treated with radiation therapy with curative intent. The disease-free survival at 2, 5, and 10 years was 50%, 33%, and 27%, respectively. The surviva ... Full text Link to item Cite

Analysis of results of radiation therapy for Stage II carcinoma of the cervix.

Journal Article Cancer · March 1, 1985 From April 1969 through December 1980, 251 patients with invasive, epidermoid carcinoma of the cervix received radical radiation therapy consisting of a combination of external beam and intracavitary therapy designed to deliver 7000 to 8000 rad to Point A ... Full text Link to item Cite

Single-fraction palliative pelvic radiation therapy in gynecologic oncology: 1,000 rads

Journal Article American Journal of Obstetrics and Gynecology · 1984 The management of the patient with advanced gynecologic malignancies presents multiple problems for the gynecologic and radiation oncologists involved in their care. When palliative management only is indicated, conventional treatment protocols occupy a si ... Cite

Poland's syndrome and lymphoma.

Journal Article Am J Dis Child · December 1983 Full text Link to item Cite

Carcinoma of the cervix stage IB: Results of treatment with radiation therapy

Journal Article International Journal of Radiation Oncology, Biology, Physics · 1983 An analysis has been made of 101 patients treated with radiation therapy for epidermoid carcinoma of the cervix Stage IB (FIGO) from January 1970 through December 1976. The patients were treated with a combination of intracavitary therapy and external beam ... Cite

Factors affecting survival in stage I and stage II carcinoma of the cervix

Journal Article Obstetrics and Gynecology · 1975 88 Cases of Stage I and Stage II carcinoma of the cervix treated with radiotherapy between April 1969 and July 1971 are reviewed. The question of whether the radiation time dose fraction relationship can be applied to the combination of external beam and i ... Cite

Leukemia and irradiation

Journal Article North Carolina Medical Journal · 1973 The therapeutic value of irradiation in leukemia is well recognized. Irradiation is used in a variety of ways to palliate symptoms as well as, in rare instances, with the intent of eradicating this disease. Of importance also is the leukemic potential of i ... Cite

New concepts in the treatment of Hodgkin's disease.

Journal Article Journal of the Tennessee Medical Association · 1970 Cite

Per cent uptake per gram. A parameter in following thyroid function.

Journal Article Investigative Radiology · 1968 Cite

Effect of radioiodide therapy on thyroid length and estimated weight.

Journal Article Journal of Nuclear Medicine · 1966 Cite