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Al-Hafeez Z Dhalla

Assistant Research Professor in the Department of Biomedical Engineering
Biomedical Engineering
PO Box 90281, Durham, NC 27708-0281
101 Science Drive, Fciemas 2574A, Durham, NC 27708-0281

Overview


My research focuses on the application of optical technologies for non-invasive, high-resolution imaging of biological tissues.  In particular, our laboratory develops optical coherence tomography (OCT), scanning laser ophthalmoscopy (SLO), light detection and ranging (LiDAR) and other optical imaging technologies for applications in the diagnosis and treatment of disease, particularly diseases of the eye. My work focuses not only on the engineering and technical development of novel imaging technologies, but also the preparation of these technologies for commercialization through clinical validation and regulatory approval.

Current Appointments & Affiliations


Assistant Research Professor in the Department of Biomedical Engineering · 2019 - Present Biomedical Engineering, Pratt School of Engineering
Faculty Network Member of the Duke Institute for Brain Sciences · 2020 - Present Duke Institute for Brain Sciences, University Institutes and Centers

Recent Publications


New Directions for Ophthalmic OCT - Handhelds, Surgery, and Robotics.

Journal Article Transl Vis Sci Technol · January 2, 2025 The introduction of optical coherence tomography (OCT) in the 1990s revolutionized diagnostic ophthalmic imaging. Initially, OCT's role was primarily in the adult ambulatory ophthalmic clinics. Subsequent advances in handheld form factors, integration into ... Full text Link to item Cite

Optical clearing with tartrazine enables deep transscleral imaging with optical coherence tomography.

Journal Article J Biomed Opt · December 2024 SIGNIFICANCE: Imaging deep structures with optical coherence tomography (OCT) is difficult in highly scattering biological tissue, such as the sclera. There is a need to visualize the suprachoroidal space and choroid through the sclera to study suprachoroi ... Full text Link to item Cite

Line-scan phase-resolved synthetic wavelength LiDAR using an off-axis holographic approach.

Journal Article Optics letters · October 2024 We demonstrate a novel, to our knowledge, approach for phase-resolved coherent 3D surface imaging that utilizes synthetic wavelength phase-based ranging and line-scan off-axis holography. Our proof-of-concept system employs an akinetic tunable laser to per ... Full text Cite
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Recent Grants


Auto-aligning hand-held OCT and OCTA for pediatric applications

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2024 - 2026

Widefield Confocal Scanning Laser Ophthalmoscope Optimized for Pediatric and Neonatal Imaging

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2022 - 2025

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Education, Training & Certifications


Duke University · 2012 Ph.D.