Overview
My research focuses on the application of optical technologies for non-invasive, high-resolution imaging of biological tissues. In particular, our laboratory develops optical coherence tomography (OCT), scanning laser ophthalmoscopy (SLO), light detection and ranging (LiDAR) and other optical imaging technologies for applications in the diagnosis and treatment of disease, particularly diseases of the eye. My work focuses not only on the engineering and technical development of novel imaging technologies, but also the preparation of these technologies for commercialization through clinical validation and regulatory approval.
Current Duke Appointments & Affiliations
Assistant Research Professor in the Department of Biomedical Engineering
·
2019 - Present
Biomedical Engineering,
Pratt School of Engineering
Faculty Network Member of the Duke Institute for Brain Sciences
·
2020 - Present
Duke Institute for Brain Sciences,
University Institutes and Centers
Recent Scholarly Works
Focus optimization for long-range OCT and short-range LiDAR
Journal article Optics Continuum · April 15, 2026 In focused Gaussian beam imaging systems, the low-numerical aperture (NA) of the beam inherently degrades signal and resolution. We demonstrate and experimentally validate a theory for optimally focusing a Gaussian beam source with a low-NA lens to maximiz ... Full text CiteOptical Coherence Tomography with Fluorescein Optical Clearing for Transscleral Image Guidance
Journal article International Journal of Translational Medicine · March 1, 2026 Background: Scattering of the sclera limits optical coherence tomography (OCT) imaging of deeper targets including lesions, malignancies, and other surgical targets. While existing applications of fluorescein dye are currently focused on fluorescence prope ... Full text CiteNew Directions for Ophthalmic OCT - Handhelds, Surgery, and Robotics.
Journal article Transl Vis Sci Technol · January 2, 2025 The introduction of optical coherence tomography (OCT) in the 1990s revolutionized diagnostic ophthalmic imaging. Initially, OCT's role was primarily in the adult ambulatory ophthalmic clinics. Subsequent advances in handheld form factors, integration into ... Full text Link to item CiteRecent Grants
Auto-aligning hand-held OCT and OCTA for pediatric applications
ResearchPrincipal Investigator · Awarded by National Eye Institute · 2024 - 2027Widefield Confocal Scanning Laser Ophthalmoscope Optimized for Pediatric and Neonatal Imaging
ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2022 - 2025A turnkey research platform to accelerate clinical translation of targeted immunomodulation-enhanced therapies
ResearchCo Investigator · Awarded by SonoVol, Inc. · 2021 - 2025View All Grants
Education
Duke University ·
2012
Ph.D.