Michael Ward Hanson | Scholars@Duke

Michael Ward Hanson
Professor of Radiology

Current research efforts within the Division of Nuclear Medicine in the Department of Radiology include the following:

1. Assessment of myocardial viability prior to myocardial revascularization in patients with coronary artery disease and a low left ventricular ejection fraction by means of a resting N-13 Ammonia myocardial perfusion scan followed by a resting and, subsequently, an exercise F-18 FDG myocardial metabolism scan.

2. Quantitative assessment of absolute coronary artery blood flow at rest and following the infusion of intravenous dipyridamole in patients with non-ischemic cardiomyopathy.

3. Evaluation of left ventricular function, assessed by MUGA studies, before and after therapy with antidepressants in patients with coronary artery disease and recent myocardial infarction.

4. Evaluation of attenuation correction programs in myocardial perfusion SPECT imaging.

Current Appointments & Affiliations

Professor of Radiology, Radiology, Nuclear Medicine, Radiology 2006
Assistant Professor of Medicine, Medicine, Cardiology, Medicine 2006

Contact Information

2525 Hosp South, Durham, NC 27710
Box 3949 Med Ctr, Durham, NC 27710
hanso003@mc.duke.edu (919) 684-7619

Background
Education, Training, & Certifications
- M.D., West Virginia University 1974
Duke Appointment History
- Assistant Clinical Professor of Medicine, Medicine, Cardiology, Medicine 1999 - 2006
- Clinical Professor of Radiology, Radiology, Nuclear Medicine, Radiology 2005 - 2006
- Associate Clinical Professor of Radiology, Radiology, Nuclear Medicine, Radiology 2001 - 2005
- Assistant Clinical Professor of Radiology, Radiology, Nuclear Medicine, Radiology 2000 - 2001
- Assistant Clinical Professor of Radiology, Radiology, Clinical Science Departments 1999 - 2000
- Assistant Professor of Radiology, Radiology, Nuclear Medicine, Radiology 1989 - 1999
- Assistant Professor of Medicine, Medicine, Clinical Science Departments 1994 - 1999
- Associate in the Department of Medicine, Medicine, Clinical Science Departments 1993 - 1994
Research
Selected Grants
- Stress & Myocardial Ischemia: Mechanisms & Treatment awarded by National Institutes of Health 1998 - 2006
Publications & Artistic Works
Selected Publications
- Book Sections
  - Coleman, RE, Borges-Neto, S, Wilkinson, RH, O'Hara, SM, Hanson, MW, Reiman, RR, Hagge, RJ, and Chin, BB. "Nuclear medicine." In Duke Radiology Case Review: Imaging, Differential Diagnosis, and Discussion: 2nd Edition, 539-. January 19, 2012.
  - Hanson, MW. "Nuclear medicine: Case 20." In Duke Radiology Case Review: Imaging, Differential Diagnosis, and Discussion: 2nd Edition, 578-579. January 19, 2012.
  - Hanson, MW. "Nuclear medicine: Case 21." In Duke Radiology Case Review: Imaging, Differential Diagnosis, and Discussion: 2nd Edition, 580-581. January 19, 2012.
  - Hanson, MW. "Nuclear medicine: Case 9." In Duke Radiology Case Review: Imaging, Differential Diagnosis, and Discussion: 2nd Edition, 556-557. January 19, 2012.
  - Hanson, MW. "Nuclear medicine: Case 8." In Duke Radiology Case Review: Imaging, Differential Diagnosis, and Discussion: 2nd Edition, 554-555. January 19, 2012.
  - Hanson, MW. "Nuclear medicine: Case 19." In Duke Radiology Case Review: Imaging, Differential Diagnosis, and Discussion: 2nd Edition, 576-577. January 19, 2012.
  - Hanson, MW. "Nuclear medicine: Case 12." In Duke Radiology Case Review: Imaging, Differential Diagnosis, and Discussion: 2nd Edition, 562-563. January 19, 2012.
  - Hanson, MW. "Nuclear medicine: Case 13." In Duke Radiology Case Review: Imaging, Differential Diagnosis, and Discussion: 2nd Edition, 564-565. January 19, 2012.
- Journal Articles
  - Rosenberg, EL, Ekman, P, Jiang, W, Babyak, M, Coleman, RE, Hanson, M, O'Connor, C, Waugh, R, and Blumenthal, JA. "Linkages Between Facial Expressions of Anger and Transient Myocardial Ischemia in Men with Coronary Artery Disease." (March 22, 2012). (Chapter) Full Text
  - Adams, GL, Trimble, MA, Brosnan, RB, Russo, CA, Rusband, D, Honeycutt, EF, Shaw, LK, Hurwitz, LM, Turkington, TG, Hanson, MW, Pagnanelli, RA, and Borges-Neto, S. "Evaluation of combined cardiac positron emission tomography and coronary computed tomography angiography for the detection of coronary artery disease." Nucl Med Commun 29, no. 7 (July 2008): 593-598. Full Text Link to Item
  - Hanson, MW, and Borges-Neto, S. "PET/CT in cardiology." (December 1, 2007): 202-216. (Chapter) Full Text
  - Adams, GL, Shaw, LK, Tuttle, RH, Hanson, MW, Pagnanelli, R, and Borges-Neto, S. "Prediction of mortality in patients with coronary artery disease undergoing vasodilator stress testing: a comparison between 99mTc-tetrofosmin and 99mTc-sestamibi." Nucl Med Commun 28, no. 6 (June 2007): 457-463. Full Text Link to Item
  - Meine, TJ, Hanson, MW, and Borges-Neto, S. "The additive value of combined assessment of myocardial perfusion and ventricular function studies." J Nucl Med 45, no. 10 (October 2004): 1721-1724. (Review) Link to Item
  - Jiang, W, Babyak, MA, Rozanski, A, Sherwood, A, O'Connor, CM, Waugh, RA, Coleman, RE, Hanson, MW, Morris, JJ, and Blumenthal, JA. "Depression and increased myocardial ischemic activity in patients with ischemic heart disease." American Heart Journal 146, no. 1 (July 2003): 55-61. Full Text
  - Pagnanelli, RA, Hanson, MW, Turkington, T, Coleman, RE, and Borges-Neto, S. "Gated 99mTc-tetrofosmin and 18F-FDG studies: a comparison of single-acquisition and separate-acquisition protocols." J Nucl Med Technol 30, no. 4 (December 2002): 175-178. Link to Item
  - Ravizzini, GC, Hanson, MW, Shaw, LK, Wong, TZ, Hagge, RJ, Pagnanelli, RA, Jain, D, Lima, HS, Coleman, RE, and Borges-Neto, S. "Efficiency comparison between 99m Tc-tetrofosmin and 99m Tc-sestamibi myocardial perfusion studies." Nucl Med Commun 23, no. 3 (March 2002): 203-208. Link to Item
  - Rosenberg, EL, Ekman, P, Jiang, W, Babyak, M, Coleman, RE, Hanson, M, O'Connor, C, Waugh, R, and Blumenthal, JA. "Linkages between facial expressions of anger and transient myocardial ischemia in men with coronary artery disease." Emotion (Washington, D.C.) 1, no. 2 (June 2001): 107-115. Full Text
  - Hanson, MW. "Scintigraphic evaluation of neuroendocrine tumors." Applied Radiology 30, no. 6 (2001): 11-17. Full Text
  - Hoffman, JM, Welsh-Bohmer, KA, Hanson, M, Crain, B, Hulette, C, Earl, N, and Coleman, RE. "FDG PET imaging in patients with pathologically verified dementia." Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine 41, no. 11 (November 2000): 1920-1928.
  - Borges-Neto, S, Javaid, A, Shaw, LK, Kong, DF, Hanson, MW, Pagnanelli, RA, Ravizzini, G, and Coleman, RE. "Poststress measurements of left ventricular function with gated perfusion SPECT: comparison with resting measurements by using a same-day perfusion-function protocol." Radiology 215, no. 2 (May 2000): 529-533. Full Text
  - Hanson, MW, Pagnanelli, RA, and Low, VH. "Hiatal hernia depicted on Tc-99m sestamibi images: myocardial perfusion imaging." Clin Nucl Med 25, no. 2 (February 2000): 142-144. Link to Item
  - Hanson, MW, Nielsen, RB, Davey, IC, and Nelson, RC. "Retrodisplaced gallbladder detected on hepatobiliary scintigraphy." Clin Nucl Med 25, no. 1 (January 2000): 57-59. Link to Item
  - Wong, TZ, Coleman, RE, Hagge, RJ, Borges-Neto, S, and Hanson, MW. "PET image interpretation: Attenuation-corrected (ATN) Vs non-attenuation corrected (NATN) images." Clinical Positron Imaging (Netherlands) 3, no. 4 (2000): 181--. Full Text
  - Davey, NC, Smith, TP, Hanson, MW, Lee, VS, Stackhouse, DJ, and Coleman, RE. "Ventilation-perfusion lung scintigraphy as a guide for pulmonary angiography in the localization of pulmonary emboli." Radiology 213, no. 1 (October 1999): 51-57. Full Text
  - Borges-Neto, S, Curtis, MA, Morris, EI, Hanson, MW, and Coleman, RE. "Combined Tc-99m sestamibi first-pass radionuclide angiography and cardiac SPECT imaging during arbutamine infusion delivered by a computerized closed-loop system." Clin Nucl Med 24, no. 1 (January 1999): 42-47. Link to Item
  - Foldvary, N, Lee, N, Hanson, MW, Coleman, RE, Hulette, CM, Friedman, AH, Bej, MD, and Radtke, RA. "Correlation of hippocampal neuronal density and FDG-PET in mesial temporal lobe epilepsy." Epilepsia 40, no. 1 (January 1999): 26-29. Link to Item
  - Hanson, MW, Schneider, AM, Enterline, DS, Feldman, JM, and Gockerman, JP. "Iodine-131-metaiodobenzylguanidine uptake in metastatic carcinoid tumor to the orbit." J Nucl Med 39, no. 4 (April 1998): 647-650. Link to Item
  - Hanson, MW. "Myocardial perfusion and functional imaging." Applied Radiology 27, no. 6 (1998): 14-18.
  - Marriott, CJC, Thorstad, W, Akabani, G, Brown, MT, McLendon, RE, Hanson, MW, and Coleman, RE. "Locally increased uptake of fluorine-18-fluorodeoxyglucose after intracavitary administration of iodine-131-labeled antibody for primary brain tumors." Journal of Nuclear Medicine 39, no. 8 SUPPL. (1998): 1376-1380.
  - Hanson, MW, Morris, EI, Borges-Neto, S, and DeLong, DM. "Analysis of cardiac arrhythmias during dobutamine pharmacologic stress testing in nuclear cardiology as related to the presence or absence of baseline arrhythmias." J Nucl Cardiol 4, no. 5 (September 1997): 372-378. Link to Item
  - Rigolin, VH, Li, JS, Hanson, MW, Sullivan, MJ, Robiolio, PA, Hearne, SE, Baker, WA, Harrison, JK, and Bashore, TM. "Role of right ventricular and pulmonary functional abnormalities in limiting exercise capacity in adults with congenital heart disease." Am J Cardiol 80, no. 3 (August 1, 1997): 315-322. Link to Item
  - Borges-Neto, S, Shaw, LJ, Kesler, KL, Hanson, MW, Peterson, ED, Morris, EI, and Coleman, RE. "Prediction of severe coronary artery disease by combined rest and exercise radionuclide angiocardiography and tomographic perfusion imaging with technetium 99m-labeled sestamibi: a comparison with clinical and electrocardiographic data." J Nucl Cardiol 4, no. 3 (May 1997): 189-194. Link to Item
  - Turkington, TG, Degrado, TR, Hanson, MW, and Coleman, RE. "Alignment of dynamic cardiac PET images for correction of motion." IEEE Transactions on Nuclear Science 44, no. 2 (1997): 235-242. Full Text
  - Hoffman, JM, Hanson, MW, Welsh, KA, Earl, N, Paine, S, Delong, D, and Coleman, RE. "Interpretation variability of 18FDG-positron emission tomography studies in dementia." Invest Radiol 31, no. 6 (June 1996): 316-322. Link to Item
  - Jiang, W, Babyak, M, Krantz, DS, Waugh, RA, Coleman, RE, Hanson, MM, Frid, DJ, McNulty, S, Morris, JJ, O'Connor, CM, and Blumenthal, JA. "Mental stress--induced myocardial ischemia and cardiac events." Jama 275, no. 21 (June 1996): 1651-1656. Full Text
  - DeGrado, TR, Hanson, MW, Turkington, TG, Delong, DM, Brezinski, DA, Vallee, J-P, Hedlund, LW, Zhang, J, Cobb, F, Sullivan, MJ, and Coleman, RE. "Estimation of myocardial blood flow for longitudinal studies with ¹³N-labeled ammonia and positron emission tomography." Journal of Nuclear Cardiology 3, no. 6 I (1996): 494-507. Full Text
  - Jiang, W, Trauner, MA, Coleman, RE, Waugh, RA, Hanson, MW, Frid, DJ, Phillips, BG, Morris, JJ, O'Connor, C, and Blumenthal, JA. "Association of physical fitness and transient myocardial ischemia in patients with coronary artery disease." J Cardiopulm Rehabil 15, no. 6 (November 1995): 431-438. Link to Item
  - Blumenthal, JA, Jiang, W, Waugh, RA, Frid, DJ, Morris, JJ, Coleman, RE, Hanson, M, Babyak, M, Thyrum, ET, and Krantz, DS. "Mental stress-induced ischemia in the laboratory and ambulatory ischemia during daily life. Association and hemodynamic features." Circulation 92, no. 8 (October 15, 1995): 2102-2108. Link to Item
  - Jiang, W, Blumenthal, JA, Hanson, MW, Coleman, RE, O'Connor, CM, Frid, D, Morris, JJ, and Waugh, RA. "Relative importance of electrode placement over number of channels in transient myocardial ischemia detection by Holter monitoring." The American Journal of Cardiology 76, no. 5 (August 1995): 350-354. Full Text
  - Worley, G, Hoffman, JM, Paine, SS, Kalman, SL, Claerhout, SJ, Boyko, OB, Kandt, RS, Santos, CC, Hanson, MW, and Oakes, WJ. "18-Fluorodeoxyglucose positron emission tomography in children and adolescents with traumatic brain injury." Dev Med Child Neurol 37, no. 3 (March 1995): 213-220. Link to Item
  - Hamblen, SM, Sell, TL, Hanson, MW, Hawk, TC, Coates, DM, Hoffman, JM, and Coleman, RE. "Clinical PET: Repositioning myocardial studies after bicycle exercise." Journal of Nuclear Medicine Technology 23, no. 1 (1995): 18-21.
  - Welsh, KA, Hoffman, JM, Earl, NL, and Hanson, MW. "Neural correlates of dementia: regional brain metabolism (FDG-PET) and the CERAD neuropsychological battery." Archives of Clinical Neuropsychology : the Official Journal of the National Academy of Neuropsychologists 9, no. 5 (October 1994): 395-409. Full Text
  - Brezinski, DA, Harrison, JK, Hanson, MW, Wilson, JS, Van Trigt, P, and Bashore, TM. "Ischemic hibernating myocardium demonstrated by positron emission tomography in anomalous origin of the left coronary artery from the pulmonary artery." Am Heart J 128, no. 1 (July 1994): 181-185. Link to Item
  - Lowe, VJ, Hoffman, JM, Hanson, MW, Paine, S, Massey, EW, Jordan, LK, Gray, L, Moon, RE, and Coleman, RE. "Cerebral imaging of decompression injury patients with 18-F-2-fluoro-2-deoxyglucose positron emission tomography." Undersea Hyperb Med 21, no. 2 (June 1994): 103-113. Link to Item
  - Schifter, T, Hoffman, JM, Hatten, HP, Hanson, MW, Coleman, RE, and DeLong, GR. "Neuroimaging in infantile autism." J Child Neurol 9, no. 2 (April 1994): 155-161. (Review) Full Text Link to Item
  - Borges-Neto, S, Puma, J, Jones, RH, Sketch, MH, Stack, R, Hanson, MW, and Coleman, RE. "Myocardial perfusion and ventricular function measurements during total coronary artery occlusion in humans. A comparison with rest and exercise radionuclide studies." Circulation 89, no. 1 (January 1994): 278-284. Link to Item
  - Heinz, R, Ferris, N, Lee, EK, Radtke, R, Crain, B, Hoffman, JM, Hanson, M, Paine, S, and Friedman, A. "MR and positron emission tomography in the diagnosis of surgically correctable temporal lobe epilepsy." American Journal of Neuroradiology 15, no. 7 (1994): 1341-1348.
  - Radtke, RA, Hanson, MW, Hoffman, JM, Heinz, ER, Walczak, TS, Lewis, DV, Coleman, RE, and Friedman, AF. "Positron emission tomography: Comparison of clinical utility in temporal lobe and extratemporal epilepsy." Journal of Epilepsy 7, no. 1 (1994): 27-33.
  - Lowe, VJ, Greer, KL, Hanson, MW, Jaszczak, RJ, and Coleman, RE. "Cardiac phantom evaluation of simultaneously acquired dual-isotope rest thallium-201/stress technetium-99m SPECT images." Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine 34, no. 11 (November 1993): 1998-2006.
  - Jaszczak, RJ, Gilland, DR, Hanson, MW, Jang, S, Greer, KL, and Coleman, RE. "Fast transmission CT for determining attenuation maps using a collimated line source, rotatable air-copper-lead attenuators and fan-beam collimation." Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine 34, no. 9 (September 1993): 1577-1586.
  - Jiang, W, Hayano, J, Coleman, ER, Hanson, MW, Frid, DJ, O'Connor, C, Thurber, D, Waugh, RA, and Blumenthal, JA. "Relation of cardiovascular responses to mental stress and cardiac vagal activity in coronary artery disease." The American Journal of Cardiology 72, no. 7 (September 1993): 551-554. Full Text
  - Hoffman, JM, Hanson, MW, and Coleman, RE. "Clinical positron emission tomography imaging." Radiol Clin North Am 31, no. 4 (July 1993): 935-959. (Review) Link to Item
  - Schifter, T, Hoffman, JM, Hanson, MW, Boyko, OB, Beam, C, Paine, S, Schold, SC, Burger, PC, and Coleman, RE. "Serial FDG-PET studies in the prediction of survival in patients with primary brain tumors." J Comput Assist Tomogr 17, no. 4 (July 1993): 509-561. Link to Item
  - Radtke, RA, Hanson, MW, Hoffman, JM, Crain, BJ, Walczak, TS, Lewis, DV, Beam, C, Coleman, RE, and Friedman, AH. "Temporal lobe hypometabolism on PET: predictor of seizure control after temporal lobectomy." Neurology 43, no. 6 (June 1993): 1088-1092. Link to Item
  - Davis, WK, Boyko, OB, Hoffman, JM, Hanson, MW, Schold, SC, Burger, PC, Friedman, AH, and Coleman, RE. "[18F]2-fluoro-2-deoxyglucose-positron emission tomography correlation of gadolinium-enhanced MR imaging of central nervous system neoplasia." AJNR Am J Neuroradiol 14, no. 3 (May 1993): 515-523. Link to Item
  - Hoffman, JM, Waskin, HA, Schifter, T, Hanson, MW, Gray, L, Rosenfeld, S, and Coleman, RE. "FDG-PET in differentiating lymphoma from nonmalignant central nervous system lesions in patients with AIDS." J Nucl Med 34, no. 4 (April 1993): 567-575. Link to Item
  - Berry, JJ, Hoffman, JM, Steenbergen, C, Baker, JA, Floyd, C, Van Trigt, P, Hanson, MW, and Coleman, RE. "Human pathologic correlation with PET in ischemic and nonischemic cardiomyopathy." J Nucl Med 34, no. 1 (January 1993): 39-47. Link to Item
  - Davis, WK, Boyko, OB, Hoffman, JM, Hanson, MW, Jr, SCS, Burger, PC, Friedman, AH, and Coleman, RE. "[¹⁸F]2-fluoro-2-deoxyglucose-positron emission tomography correlation of gadolinium-enhanced MR imaging of central nervous system neoplasia." American Journal of Neuroradiology 14, no. 3 (1993): 515-527.
  - Heinle, S, Hanson, M, Gracey, L, Coleman, RE, and Kisslo, J. "Correlation of adenosine echocardiography and thallium scintigraphy." American Heart Journal 125, no. 6 (1993): 1606-1613. Full Text
  - Rosenfeld, SS, Hoffman, JM, Coleman, RE, Glantz, MJ, Hanson, MW, and Schold, SC. "Studies of primary central nervous system lymphoma with fluorine-18-fluorodeoxyglucose positron emission tomography." Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine 33, no. 4 (April 1992): 532-536.
  - Hoffman, JM, Hanson, MW, Friedman, HS, Hockenberger, BM, Oakes, WJ, Halperin, EC, and Coleman, RE. "FDG-PET in pediatric posterior fossa brain tumors." J Comput Assist Tomogr 16, no. 1 (January 1992): 62-68. Link to Item
  - Hanson, MW, Glantz, MJ, Hoffman, JM, Friedman, AH, Burger, PC, Schold, SC, and Coleman, RE. "FDG-PET in the selection of brain lesions for biopsy." J Comput Assist Tomogr 15, no. 5 (September 1991): 796-801. Link to Item
  - Berry, JJ, Baker, JA, Pieper, KS, Hanson, MW, Hoffman, JM, and Coleman, RE. "The effect of metabolic milieu on cardiac PET imaging using fluorine-18-deoxyglucose and nitrogen-13-ammonia in normal volunteers." Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine 32, no. 8 (August 1991): 1518-1525.
  - Hanson, MW, Feldman, JM, Beam, CA, Leight, GS, and Coleman, RE. "Iodine 131-labeled metaiodobenzylguanidine scintigraphy and biochemical analyses in suspected pheochromocytoma." Arch Intern Med 151, no. 7 (July 1991): 1397-1402. Link to Item
  - Coleman, RE, Hoffman, JM, Hanson, MW, Sostman, HD, and Schold, SC. "Clinical application of PET for the evaluation of brain tumors." J Nucl Med 32, no. 4 (April 1991): 616-622. (Review) Link to Item
  - Glantz, MJ, Hoffman, JM, Coleman, RE, Friedman, AH, Hanson, MW, Burger, PC, Herndon, JE, Meisler, WJ, and Schold, SC. "Identification of early recurrence of primary central nervous system tumors by [18F]fluorodeoxyglucose positron emission tomography." Annals of Neurology 29, no. 4 (April 1991): 347-355. Full Text
  - Hanson, MW, and Coleman, RE. "Pulmonary nuclear medicine evaluation of thromboembolic disease." J Thorac Imaging 4, no. 4 (October 1989): 40-57. (Review) Link to Item
  - Hanson, MW, Feldman, JM, Blinder, RA, Moore, JO, and Coleman, RE. "Carcinoid tumors: iodine-131 MIBG scintigraphy." Radiology 172, no. 3 (September 1989): 699-703. Full Text
  - Hamblen, SM, Harris, CC, Hanson, MW, and Coleman, RE. "Clinical PET: Study scheduling and coordination." Journal of Nuclear Medicine 30, no. 11 (1989): 2Ab-.
  - Hanson, MW, Radtke, RA, Schold, CS, Glantz, MJ, Rosenfeld, SS, and Coleman, RE. "Utility of FDG-PET in the evaluation of seizures and primary brain tumors." Journal of Nuclear Medicine 30, no. 11 (1989): 2Ab-.
  - Hanson, MW, and Sostman, D. "Changes in myocardial perfusion reserve after PTCA: noninvasive assessment with positron tomography." Invest Radiol 23, no. 6 (June 1988): 488-489. Link to Item

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Education, Training, & Certifications

Duke Appointment History

Selected Grants

Selected Publications

Book Sections

Journal Articles