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Hanzhang Xu

Associate Professor in the School of Nursing
School of Nursing
311 Trent Drive, Ipe 4261, Durham, NC 27710

Overview


Dr. Hanzhang Xu, PhD, RN, FAAN, is an Associate Professor at the Duke University School of Nursing with joint appointments at the Duke University School of Medicine in the Department of Family Medicine and Community Health and the Duke-NUS Medical School in the Health Services & Systems Research Signature Program. She also serves as a Senior Fellow at Duke's Center for the Study of Aging and Human Development and as a Faculty Affiliate at the Duke Global Health Institute.

As a clinician scientist, Dr. Xu’s research and scholarship center around social determinants of health and disparities in health care and outcomes in diverse older adult populations, with a particular focus on cardiovascular and brain health. Her current program of research falls under two themes: (i) health disparities in a multinational context, with a particular focus on the cognitive function and dementia care among older adults; and (ii) the integration of patient-reported social factors in cardiovascular outcome research.

She has led several research projects funded by the National Institutes of Health (NIH) that leverage the strengths of big data repositories such as electronic health records (EHR), Medicare claims, national survey data and disease registries to improve the cardiovascular and brain health of older adults, with a total award amount being over $5 million. Her work in these areas has been widely cited by researchers in at least 53 countries across 6 continents, and has been featured in international media outlets, including in Yahoo!, TIME, Forbes, and the Mirror.

Dr. Xu is a Fellow of the American Academy of Nursing and was inducted into Sigma Theta Tau International Honor Society of Nursing. She serves on the Editorial Board of the Journal of Aging and Health.

Xu earned her PhD from Duke University.

Current Appointments & Affiliations


Associate Professor in the School of Nursing · 2024 - Present School of Nursing
Associate Professor in Family Medicine and Community Health · 2024 - Present Family Medicine and Community Health, Clinical Science Departments

In the News


Published June 16, 2025
Reducing Dementia Risk through Later-Life Learning
Published February 14, 2025
Duke and Duke-NUS forge new frontiers in climate health research with S$1million funding
Published November 1, 2024
Faculty, Alumni, Colleagues Inducted as Fellows into American Academy of Nursing

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Recent Publications


Digital Divide or Educational Divide? The Impact of Social Media on COVID-19 Vaccination in Middle-Aged and Older Adults.

Journal Article medRxiv · September 7, 2025 The spread of disinformation and harmful content on social media is well-known. However, most research focuses on the negative influence of social media on the well-being of adolescents and teenagers. We used data from the 2022 Health and Retirement Study ... Full text Link to item Cite

Racial and ethnic disparities in longitudinal trajectories of hospitalizations in patients diagnosed with heart failure.

Journal Article Am Heart J · September 2025 BACKGROUND: Racial and ethnic disparities in hospitalizations among heart failure (HF) patients have been well documented. However, little is known about racial and ethnic differences in the long-term trajectories of hospital admissions that follow the dia ... Full text Link to item Cite
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Recent Grants


Characterizing Family Structure, Care Utilization, and Well-Being among Persons with ADRD in the Asian Region

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2025 - 2030

Poststroke Cognitive Impairment and Dementia

ResearchPrincipal Investigator · Awarded by University of Texas - Southwestern · 2024 - 2029

Duke/UNC ADAR Program

Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 2024 - 2029

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Education, Training & Certifications


Duke University, School of Nursing · 2018 Ph.D.