Scholars@Duke

• Research
• 

  Selected Grants

  • Balancing Risks and Benefits of Direct Oral Anticoagulants in Older Ischemic Stroke Patients with Atrial Fibrillation awarded by National Institutes of Health 2020 - 2025
  • The Impact of Quality Metrics on Outcomes among Elderly Heart Failure Patients awarded by Dartmouth College 2019 - 2021
  • National Surveillance of Stroke Outcomes and Quality of Care using the Get With the Guidelines(GWTG) Stroke Registry awarded by University of California - Los Angeles 2017 - 2020
  • Patient-centered Research into Outcomes Stroke patients Prefer and Effectiveness Research awarded by Patient Centered Outcomes Research Institute 2013 - 2020
  • Mapping Quality in the Stroke System of Care: Do hospitals that share in the care of Acute Stroke patients also share awarded by Massachusetts General Hospital 2016 - 2019
• Publications & Artistic Works
• 

  Selected Publications

  • Academic Articles

    • Ziaeian, B., Xu, H., Matsouaka, R. A., Xian, Y., Khan, Y., Schwamm, L. S., … Fonarow, G. C. (2021). National surveillance of stroke quality of care and outcomes by applying post-stratification survey weights on the Get With The Guidelines-Stroke patient registry. Bmc Med Res Methodol, 21(1), 23. https://doi.org/10.1186/s12874-021-01214-z
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    • Dalgaard, F., Xu, H., Matsouaka, R. A., Russo, A. M., Curtis, A. B., Rasmussen, P. V., … Al-Khatib, S. M. (2020). Management of Atrial Fibrillation in Older Patients by Morbidity Burden: Insights From Get With The Guidelines-Atrial Fibrillation. J Am Heart Assoc, 9(23), e017024. https://doi.org/10.1161/JAHA.120.017024
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    • Sterling, M. R., Kern, L. M., Safford, M. M., Jones, C. D., Feldman, P. H., Fonarow, G. C., … Albert, N. M. (2020). Home Health Care Use and Post-Discharge Outcomes After Heart Failure Hospitalizations. Jacc Heart Fail, 8(12), 1038–1049. https://doi.org/10.1016/j.jchf.2020.06.009
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    • Akbik, F., Xu, H., Xian, Y., Shah, S., Smith, E. E., Bhatt, D. L., … Schwamm, L. H. (2020). Trends in Reperfusion Therapy for In-Hospital Ischemic Stroke in the Endovascular Therapy Era. Jama Neurol. https://doi.org/10.1001/jamaneurol.2020.3362
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    • Figueroa, J. F., Wadhera, R. K., Frakt, A. B., Fonarow, G. C., Heidenreich, P. A., Xu, H., … Joynt Maddox, K. E. (2020). Quality of Care and Outcomes Among Medicare Advantage vs Fee-for-Service Medicare Patients Hospitalized With Heart Failure. Jama Cardiol. https://doi.org/10.1001/jamacardio.2020.3638
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    • Luo, N., Hammill, B. G., DeVore, A. D., Xu, H., Fonarow, G. C., Albert, N. M., … Mentz, R. J. (2020). Outcomes and cost among Medicare beneficiaries hospitalized for heart failure assigned to accountable care organizations. Am Heart J, 226, 13–23. https://doi.org/10.1016/j.ahj.2020.04.028
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    • Sharma, A., Wu, J., Xu, H., Hernandez, A., Felker, G. M., Al-Khatib, S., … DeVore, A. (2020). Comparative Effectiveness of Primary Prevention Implantable Cardioverter-Defibrillators in Older Heart Failure Patients With Diabetes Mellitus. J Am Heart Assoc, 9(12), e012405. https://doi.org/10.1161/JAHA.119.012405
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    • Fudim, M., Sayeed, S., Xu, H., Matsouaka, R. A., Heidenreich, P. A., Velazquez, E. J., … DeVore, A. D. (2020). Representativeness of the PIONEER-HF Clinical Trial Population in Patients Hospitalized With Heart Failure and Reduced Ejection Fraction. Circ Heart Fail, 13(4), e006645. https://doi.org/10.1161/CIRCHEARTFAILURE.119.006645
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    • O’Connor, K. D., Brophy, T., Fonarow, G. C., Blankstein, R., Swaminathan, R. V., Xu, H., … DeVore, A. D. (2020). Testing for Coronary Artery Disease in Older Patients With New-Onset Heart Failure: Findings From Get With The Guidelines-Heart Failure. Circ Heart Fail, 13(4), e006963. https://doi.org/10.1161/CIRCHEARTFAILURE.120.006963
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    • Naidech, A. M., Lawlor, P. N., Xu, H., Fonarow, G. C., Xian, Y., Smith, E. E., … Kording, K. P. (2020). Probing the Effective Treatment Thresholds for Alteplase in Acute Ischemic Stroke With Regression Discontinuity Designs. Front Neurol, 11, 961. https://doi.org/10.3389/fneur.2020.00961
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    • Sayeed, S., Fudim, M., Devore, A. D., Xu, H., Matsouaka, R. A., Heidenreich, P. A., … Hernandez, A. F. (2019). PARAGON-HF Clinical Trial Eligibility in a Population of Patients Hospitalized With Heart Failure. J Card Fail, 25(12), 1009–1011. https://doi.org/10.1016/j.cardfail.2019.10.003
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    • Prabhakaran, S., Messé, S. R., Kleindorfer, D., Smith, E. E., Fonarow, G. C., Xu, H., … Schwamm, L. H. (2019). Cryptogenic stroke: Contemporary trends, treatments, and outcomes in the United States. Neurology: Clinical Practice, 00(00), 1–10. https://doi.org/10.1212/cpj.0000000000000736
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    • Ali-Ahmed, F., Federspiel, J. J., Liang, L., Xu, H., Sevilis, T., Hernandez, A. F., … Xian, Y. (2019). Intravenous Tissue Plasminogen Activator in Stroke Mimics. Circ Cardiovasc Qual Outcomes, 12(8), e005609. https://doi.org/10.1161/CIRCOUTCOMES.119.005609
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    • Xian, Y., Xu, H., O’Brien, E. C., Shah, S., Thomas, L., Pencina, M. J., … Hernandez, A. F. (2019). Clinical Effectiveness of Direct Oral Anticoagulants vs Warfarin in Older Patients With Atrial Fibrillation and Ischemic Stroke: Findings From the Patient-Centered Research Into Outcomes Stroke Patients Prefer and Effectiveness Research (PROSPER) Study. Jama Neurol. https://doi.org/10.1001/jamaneurol.2019.2099
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    • Ehrlich, M. E., Liang, L., Xu, H., Kosinski, A. S., Hernandez, A. F., Schwamm, L. H., … Xian, Y. (2019). Intravenous Tissue-Type Plasminogen Activator in Acute Ischemic Stroke Patients With History of Stroke Plus Diabetes Mellitus. Stroke, 50(6), 1497–1503. https://doi.org/10.1161/STROKEAHA.118.024172
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    • Dandapat, S., Siddiqui, F. M., Fonarow, G. C., Bhatt, D. L., Xu, H., Matsouaka, R., … Smith, E. E. (2019). A paradoxical relationship between hemoglobin A1C and in-hospital mortality in intracerebral hemorrhage patients. Heliyon, 5(5), e01659. https://doi.org/10.1016/j.heliyon.2019.e01659
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    • Ziaeian, B., Hernandez, A. F., DeVore, A. D., Wu, J., Xu, H., Heidenreich, P. A., … Fonarow, G. C. (2019). Long-term outcomes for heart failure patients with and without diabetes: From the Get With The Guidelines-Heart Failure Registry. Am Heart J, 211, 1–10. https://doi.org/10.1016/j.ahj.2019.01.006
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    • Piccini, J. P., Xu, H., Cox, M., Matsouaka, R. A., Fonarow, G. C., Butler, J., … Get With The Guidelines-AFIB Clinical Working Group and Hospitals, . (2019). Adherence to Guideline-Directed Stroke Prevention Therapy for Atrial Fibrillation Is Achievable. Circulation, 139(12), 1497–1506. https://doi.org/10.1161/CIRCULATIONAHA.118.035909
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    • Menon, B. K., Xu, H., Cox, M., Saver, J. L., Goyal, M., Peterson, E., … Smith, E. E. (2019). Components and Trends in Door to Treatment Times for Endovascular Therapy in Get With The Guidelines-Stroke Hospitals. Circulation, 139(2), 169–179. https://doi.org/10.1161/CIRCULATIONAHA.118.036701
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    • Luo, N., Xu, H., Jneid, H., Fonarow, G. C., Lopes, R. D., Piccini, J. P., … Al-Khatib, S. M. (2018). Use of Oral Anticoagulation in Eligible Patients Discharged With Heart Failure and Atrial Fibrillation. Circ Heart Fail, 11(10), e005356. https://doi.org/10.1161/CIRCHEARTFAILURE.118.005356
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    • Warraich, H. J., Xu, H., DeVore, A. D., Matsouaka, R., Heidenreich, P. A., Bhatt, D. L., … Allen, L. A. (2018). Trends in Hospice Discharge and Relative Outcomes Among Medicare Patients in the Get With The Guidelines-Heart Failure Registry. Jama Cardiol, 3(10), 917–926. https://doi.org/10.1001/jamacardio.2018.2678
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    • Echouffo-Tcheugui, J. B., Xu, H., Matsouaka, R. A., Xian, Y., Schwamm, L. H., Smith, E. E., … Fonarow, G. C. (2018). Diabetes and long-term outcomes of ischaemic stroke: findings from Get With The Guidelines-Stroke. Eur Heart J, 39(25), 2376–2386. https://doi.org/10.1093/eurheartj/ehy036
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    • Ziaeian, B., Heidenreich, P. A., Xu, H., DeVore, A. D., Matsouaka, R. A., Hernandez, A. F., … Fonarow, G. C. (2018). Medicare Expenditures by Race/Ethnicity After Hospitalization for Heart Failure With Preserved Ejection Fraction. Jacc Heart Fail, 6(5), 388–397. https://doi.org/10.1016/j.jchf.2017.12.007
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    • Li, S., Fonarow, G. C., Mukamal, K., Xu, H., Matsouaka, R. A., Devore, A. D., & Bhatt, D. L. (2018). Sex and Racial Disparities in Cardiac Rehabilitation Referral at Hospital Discharge and Gaps in Long-Term Mortality. J Am Heart Assoc, 7(8). https://doi.org/10.1161/JAHA.117.008088
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    • Chang, L. L., Xu, H., DeVore, A. D., Matsouaka, R. A., Yancy, C. W., Fonarow, G. C., … Hernandez, A. F. (2018). Timing of Postdischarge Follow-Up and Medication Adherence Among Patients With Heart Failure. J Am Heart Assoc, 7(7). https://doi.org/10.1161/JAHA.117.007998
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    • Shah, K. S., Xu, H., Matsouaka, R. A., Bhatt, D. L., Heidenreich, P. A., Hernandez, A. F., … Fonarow, G. C. (2017). Heart Failure With Preserved, Borderline, and Reduced Ejection Fraction: 5-Year Outcomes. J Am Coll Cardiol, 70(20), 2476–2486. https://doi.org/10.1016/j.jacc.2017.08.074
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    • Reeves, M. J., Fonarow, G. C., Xu, H., Matsouaka, R. A., Xian, Y., Saver, J., … Smith, E. E. (2017). Is Risk-Standardized In-Hospital Stroke Mortality an Adequate Proxy for Risk-Standardized 30-Day Stroke Mortality Data? Findings From Get With The Guidelines-Stroke. Circ Cardiovasc Qual Outcomes, 10(10). https://doi.org/10.1161/CIRCOUTCOMES.117.003748
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    • Ziaeian, B., Heidenreich, P. A., Xu, H., DeVore, A. D., Matsouaka, R. A., Hernandez, A. F., … Fonarow, G. C. (2017). Race/Ethnic Differences in Outcomes Among Hospitalized Medicare Patients With Heart Failure and Preserved Ejection Fraction. Jacc Heart Fail, 5(7), 483–493. https://doi.org/10.1016/j.jchf.2017.02.012
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    • Xian, Y., Xu, H., Liang, L., Hernandez, A. F., Wang, T. Y., & Peterson, E. D. (2017). An Initial Evaluation of the Impact of Pokémon GO on Physical Activity. J Am Heart Assoc, 6(5). https://doi.org/10.1161/JAHA.116.005341
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    • Xian, Y., O’Brien, E. C., Liang, L., Xu, H., Schwamm, L. H., Fonarow, G. C., … Peterson, E. D. (2017). Association of Preceding Antithrombotic Treatment With Acute Ischemic Stroke Severity and In-Hospital Outcomes Among Patients With Atrial Fibrillation. Jama, 317(10), 1057–1067. https://doi.org/10.1001/jama.2017.1371
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    • Xian, Y., Xu, H., Lytle, B., Blevins, J., Peterson, E. D., Hernandez, A. F., … Fonarow, G. C. (2017). Use of Strategies to Improve Door-to-Needle Times With Tissue-Type Plasminogen Activator in Acute Ischemic Stroke in Clinical Practice: Findings from Target: Stroke. Circ Cardiovasc Qual Outcomes, 10(1). https://doi.org/10.1161/CIRCOUTCOMES.116.003227
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    • Echouffo-Tcheugui, J. B., Xu, H., DeVore, A. D., Schulte, P. J., Butler, J., Yancy, C. W., … Fonarow, G. C. (2016). Temporal trends and factors associated with diabetes mellitus among patients hospitalized with heart failure: Findings from Get With The Guidelines-Heart Failure registry. Am Heart J, 182, 9–20. https://doi.org/10.1016/j.ahj.2016.07.025
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    • Pandey, A., Golwala, H., Xu, H., DeVore, A. D., Matsouaka, R., Pencina, M., … Fonarow, G. C. (2016). Association of 30-Day Readmission Metric for Heart Failure Under the Hospital Readmissions Reduction Program With Quality of Care and Outcomes. Jacc Heart Fail, 4(12), 935–946. https://doi.org/10.1016/j.jchf.2016.07.003
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    • Medford-Davis, L. N., Fonarow, G. C., Bhatt, D. L., Xu, H., Smith, E. E., Suter, R., … Schwamm, L. H. (2016). Impact of Insurance Status on Outcomes and Use of Rehabilitation Services in Acute Ischemic Stroke: Findings From Get With The Guidelines-Stroke. J Am Heart Assoc, 5(11). https://doi.org/10.1161/JAHA.116.004282
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    • Himes, J. E., Ho, C., Nguyen, Q. N., Amos, J. D., Xu, H., Chan, C., … Permar, S. R. (2016). Characterization of Simian Immunodeficiency Virus Variants Anatomically Compartmentalized in Plasma and Milk in Chronically Infected African Green Monkeys. J Virol, 90(19), 8795–8808. https://doi.org/10.1128/JVI.00701-16
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    • O’Brien, E. C., Xian, Y., Xu, H., Wu, J., Saver, J. L., Smith, E. E., … Fonarow, G. C. (2016). Hospital Variation in Home-Time After Acute Ischemic Stroke: Insights From the PROSPER Study (Patient-Centered Research Into Outcomes Stroke Patients Prefer and Effectiveness Research). Stroke, 47(10), 2627–2633. https://doi.org/10.1161/STROKEAHA.116.013563
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  • Conference Papers

    • Mentz, R. J., Xu, H., O’Brien, E. C., Thomas, L., Alexy, T., Gupta, B., … Hernandez, A. F. (2020). PROVIDE-HF primary results: Patient-Reported Outcomes inVestigation following Initiation of Drug therapy with Entresto (sacubitril/valsartan) in heart failure. In Am Heart J (Vol. 230, pp. 35–43). United States. https://doi.org/10.1016/j.ahj.2020.09.012
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    • Kumar, N., Xu, H., Matsouaka, R., Garg, N., Pandey, A., Piccini, J. P., … Fonarow, G. C. (2019). Patient Characteristics, Care Patterns, and Outcomes of Atrial Fibrillation Associated Hospitalizations in Patients With Chronic Kidney Disease and End-stage Renal Disease. In Circulation (Vol. 140).
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    • Sayeed, S., Fudim, M., Xu, H., Matsouaka, R., Heidenreich, P. A., Yancy, C. W., … DeVore, A. D. (2019). Representativeness of the PIONEER-HF Clinical Trial Population in Patients Hospitalized with Heart Failure. In Journal of Cardiac Failure (Vol. 25, pp. S151–S151). Elsevier BV. https://doi.org/10.1016/j.cardfail.2019.07.436
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    • Shah, S., Xu, H., Xian, Y., Maisch, L., Hannah, D., Lindholm, B., … O’Brien, E. C. (2018). Patterns of Discharge Antidepressant Therapy Use After Acute Ischemic Stroke: Insights From the Prosper Study. In Stroke (Vol. 49). Los Angeles, CA: LIPPINCOTT WILLIAMS & WILKINS.
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    • Chang, L. L., Xu, H., DeVore, A. D., Matsouaka, R., Yancy, C., Fonarow, G. C., … Hernandez, A. F. (2017). Timing of Postdischarge Follow-Up and Medication Adherence Among Heart Failure Patients. In Circulation (Vol. 136). Anaheim, CA: LIPPINCOTT WILLIAMS & WILKINS.
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    • Luo, N., Xu, H., Jneid, H., Fonarow, G. C., Lopes, R. D., Granger, C. B., … Al-Khatib, S. M. (2017). High Use of Oral Anticoagulation in Eligible Patients Discharged With Heart Failure and Atrial Fibrillation Irrespective of Ejection Fraction: Insights From the AHA Get With The Guidelines- Atrial Fibrillation Program. In Circulation (Vol. 136). Anaheim, CA: LIPPINCOTT WILLIAMS & WILKINS.
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    • Shah, K. S., Xu, H., Matsouaka, R. A., Bhatt, D. L., Heidenreich, P. A., Hernandez, A. F., … Fonarow, G. C. (2017). Five-Year Outcomes in Patients Hospitalized With Heart Failure With Preserved, Borderline, and Reduced Ejection Fraction in the Medicare Population. In Circulation (Vol. 136). Anaheim, CA: LIPPINCOTT WILLIAMS & WILKINS.
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    • Xu, H., Xian, Y., Liang, L., Hernandez, A. F., Wang, T. Y., & Peterson, E. D. (2017). Does Pokemon Go Help Players be More Active? An Evaluation of Pokemon Go and Physical Activity. In Circulation (Vol. 135). Portland, OR: LIPPINCOTT WILLIAMS & WILKINS.
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    • Pandey, A., Golwala, H., Xu, H., DeVore, A., Matsouaka, R., Pencina, M., … Fonarow, G. (2016). Association of Risk Adjusted 30 Day Heart Failure Readmission Rates Under the Hospital Readmissions Reduction Program With Quality of Care and Outcomes: Findings From the American Heart Association Get With the Guidelines-Heart Failure Program. In Circulation (Vol. 134). Pentagon City, VA: LIPPINCOTT WILLIAMS & WILKINS.
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