Frank E. Harrell Jr.

My largest responsibility is directing the statistical center for a 5-hospital study of critically ill hospitalized adults involving 9,100 patients. This study involves such issues as critical care medicine, prognostication, patterns of usage of “do not resuscitate orders”, quality of life, functional disability, patient preferences for resuscitation, and handling missing data. I have two statistical methods grants from the Agency for Health Care Policy and Research. One involves studying and developing methods of survival analysis that are useful in outcomes research, and the other addresses whether neural networks have advantages over traditional statistical methods in developing clinical prediction models.

I also consult on the design and analysis of clinical trials and work in the area of statistical computing.