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Laura Jean Havrilesky

Professor of Obstetrics and Gynecology
Obstetrics and Gynecology, Gynecologic Oncology
Box 3079 Med Ctr, Durham, NC 27710
25172 Morris Bldg, Durham, NC 27710

Featured Works


Management of platinum-sensitive recurrent ovarian cancer: a cost-effectiveness analysis.

Journal article Gynecol Oncol · November 2007 Featured Publication OBJECTIVE: We wished to compare the cost-effectiveness of three chemotherapy regimens for treatment of recurrent platinum-sensitive ovarian cancer. METHODS: A Markov decision tree was constructed comparing three chemotherapy regimens: (1) carboplatin alone ... Full text Link to item Cite

Outcomes in surgical stage I uterine papillary serous carcinoma.

Journal article Gynecol Oncol · June 2007 Featured Publication OBJECTIVE: The optimal management of patients with stage I uterine papillary serous carcinoma (UPSC) is unclear. We sought to determine whether outcomes of women with surgical stage I UPSC differ with and without adjuvant therapy. METHODS: Retrospective mu ... Full text Link to item Cite

The prognostic significance of positive peritoneal cytology and adnexal/serosal metastasis in stage IIIA endometrial cancer.

Journal article Gynecol Oncol · February 2007 Featured Publication OBJECTIVE: The clinical significance and optimal management of patients with stage IIIA endometrial cancer are controversial. We sought to determine whether recurrence and survival of patients with stage IIIA endometrial cancer differ with surgical patholo ... Full text Link to item Cite

Resection of lymph node metastases influences survival in stage IIIC endometrial cancer.

Journal article Gynecol Oncol · December 2005 Featured Publication OBJECTIVE: Surgical staging of endometrial cancer identifies those patients with microscopic metastatic disease most likely to benefit from adjuvant therapy and may also confer therapeutic benefit. Our objective was to compare survival of patients who unde ... Full text Link to item Cite

Retrospective analysis of selective lymphadenectomy in apparent early-stage endometrial cancer.

Journal article J Clin Oncol · June 1, 2005 Featured Publication PURPOSE: Selective lymphadenectomy is widely accepted in the management of endometrial cancer. Purported benefits are individualization of adjuvant therapy based on extent of disease and resection of occult metastases. Our goal was to assess effects of the ... Full text Link to item Cite

FDG-PET for management of cervical and ovarian cancer.

Journal article Gynecol Oncol · April 2005 Featured Publication OBJECTIVE: To assess the diagnostic performance of Positron Emission Tomography using fluorodeoxyglucose (FDG-PET) in comparison to conventional imaging modalities in the assessment of patients with cervical and ovarian cancer. METHODS: Studies published b ... Full text Link to item Cite

Radical hysterectomy and pelvic lymphadenectomy for stage IB2 cervical cancer.

Journal article Gynecol Oncol · May 2004 Featured Publication OBJECTIVE: We wished to evaluate survival and adverse outcomes of patients with stage IB2 cervical cancer treated primarily with radical hysterectomy and lymphadenectomy. METHODS: A review was performed of all patients undergoing primary radical hysterecto ... Full text Link to item Cite

Predictors of clinical outcomes in the laparoscopic management of adnexal masses.

Journal article Obstet Gynecol · August 2003 Featured Publication OBJECTIVE: Laparoscopy has become an accepted approach in the management of adnexal masses. We evaluated clinical outcomes of laparoscopic management of adnexal masses thought to be benign preoperatively. METHODS: We performed a retrospective study of pati ... Full text Link to item Cite

Weekly low-dose carboplatin and paclitaxel in the treatment of recurrent ovarian and peritoneal cancer.

Journal article Gynecol Oncol · January 2003 Featured Publication OBJECTIVES: Weekly paclitaxel alone has moderate activity in the salvage treatment of recurrent ovarian cancer and is associated with a favorable toxicity profile. Combination paclitaxel and carboplatin is a well-established first-line regimen for ovarian ... Full text Link to item Cite