Heather M. Stapleton

Conference Cancer Prevention Research · July 1, 2020 AbstractThyroid cancer is the fastest-increasing cancer in the U.S., and papillary thyroid cancer (PTC) accounts for >80% of incident cases. Data also indicate that the incidence of PTC varies geograp ... Full text Cite

Gestational Exposure to Perfluorooctanoic Acid (PFOA) or Its Replacement GenX Induces Adverse Pregnancy Outcomes and Disrupts the Placenta

Conference BIRTH DEFECTS RESEARCH · June 2020 Link to item Cite

Sex‐Dependent Metabolic Syndrome Phenotype Produced By Developmental Exposure to Indoor Flame Retardants

Conference The FASEB Journal · April 2020 Chronic low level exposure to endocrine disrupting chemicals such as polybrominated diphenyl ethers (PBDEs) have been associated with diabetogenic and obesogenic phenotypes but mechan ... Full text Cite

The Placenta: A Mediator of Thyroid Hormone Disruption Following Gestational Exposure to Flame Retardants

Conference INTERNATIONAL JOURNAL OF TOXICOLOGY · January 1, 2020 Link to item Cite

Metabolites Associated With Per- and Polyfluoroalkyl Substance (PFAS) Levels in an Ethnically Diverse Underserved At-Risk Rural Population

Conference CIRCULATION · November 19, 2019 Link to item Cite

Validating Silicone Wristbands to Measure Pesticide Exposures Among Older Adults -- Proof-of-Concept Study

Conference · November 8, 2019 Silicone wristbands have been used to measure exposure to pesticides and other chemicals among children and younger farm workers, but not in older adults. Thus, we aimed to examine exposure to pesticides using silicone wristbands in a small cohort of older ... Full text Link to item Cite

Inhibition of Human Liver Carboxylesterase (hCE1) by Organophosphate Ester Flame Retardants and Plasticizers: Implications for Pharmacotherapy.

Conference Toxicological sciences : an official journal of the Society of Toxicology · October 2019 Organophosphate ester (OPE) flame retardants and plasticizers, consumer product additives with widespread human exposure, were evaluated for their effect on the activity of purified human liver carboxylesterase (hCE1). Four of the 15 OPEs tested had IC50 v ... Full text Cite

Tissue-Specific Accumulation of PBDEs in the Placenta and Effects on Thyroid Regulation

Conference INTERNATIONAL JOURNAL OF TOXICOLOGY · January 1, 2019 Link to item Cite

Disruption of Nuclear Receptor Signaling Alters Triphenyl Phosphate-Induced Cardiotoxicity in Zebrafish Embryos

Conference BIRTH DEFECTS RESEARCH · May 15, 2018 Link to item Cite

Inhibition of Carboxylesterase Enzymes by Isopropylated Triarylphosphate Ester Flame Retardants: Implications for Pharmacotherapy and Cardiovascular Disease

Conference INTERNATIONAL JOURNAL OF TOXICOLOGY · January 1, 2018 Link to item Cite

Halogenated organophosphate flame retardants: Developmental neurotoxicity and possible mechanisms of action

Conference Neurotoxicology and Teratology · May 2015 Full text Cite

Inhibition of thyroid hormone sulfotransferase activity by brominated flame retardants in a human choriocarcinoma cell line, BeWo

Conference ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY · March 22, 2015 Link to item Cite

Tissue Distribution of Polybrominated Diphenyl Ethers in Rats Following Oral Exposure and the Relationship to Body Burdens

Conference EPIDEMIOLOGY · November 1, 2008 Link to item Cite

Biotransformation and persistent metabolites of organohalogen contaminants in model marine and aquatic wildlife and populations

Conference DRUG METABOLISM REVIEWS · August 1, 2004 Link to item Cite

Heather M. Stapleton

Scholarly Works - Conferences

Triphenyl Phosphate-Induced Pericardial Edema in Zebrafish Embryos is Dependent on the Ionic Strength of Exposure Media

Abstract A13: Papillary thyroid cancer clusters in North Carolina 1997-2017

Gestational Exposure to Perfluorooctanoic Acid (PFOA) or Its Replacement GenX Induces Adverse Pregnancy Outcomes and Disrupts the Placenta

Sex‐Dependent Metabolic Syndrome Phenotype Produced By Developmental Exposure to Indoor Flame Retardants

The Placenta: A Mediator of Thyroid Hormone Disruption Following Gestational Exposure to Flame Retardants

Metabolites Associated With Per- and Polyfluoroalkyl Substance (PFAS) Levels in an Ethnically Diverse Underserved At-Risk Rural Population

Validating Silicone Wristbands to Measure Pesticide Exposures Among Older Adults -- Proof-of-Concept Study

Inhibition of Human Liver Carboxylesterase (hCE1) by Organophosphate Ester Flame Retardants and Plasticizers: Implications for Pharmacotherapy.

Tissue-Specific Accumulation of PBDEs in the Placenta and Effects on Thyroid Regulation

Disruption of Nuclear Receptor Signaling Alters Triphenyl Phosphate-Induced Cardiotoxicity in Zebrafish Embryos

Inhibition of Carboxylesterase Enzymes by Isopropylated Triarylphosphate Ester Flame Retardants: Implications for Pharmacotherapy and Cardiovascular Disease

Halogenated organophosphate flame retardants: Developmental neurotoxicity and possible mechanisms of action

Inhibition of thyroid hormone sulfotransferase activity by brominated flame retardants in a human choriocarcinoma cell line, BeWo

Behavioral effects of short-term exposure to Firemaster 550

The Organic Anion Transporting Protein (OATP) Family in a Teleost Fish Model

Exposure to Polybrominated Diphenyl Ethers in Indoor Environments

Relationships Between Brominated Flame Retardant Concentrations in House Dust and Serum Hormone Levels in Men

Tissue Distribution of Polybrominated Diphenyl Ethers in Rats Following Oral Exposure and the Relationship to Body Burdens

Televisions as Sources of DecaBDE in House Dust

PBDE Levels in Indoor Air and Dust Collected From US Urban Residences

Certification of a house dust standard reference material for determination of organic contaminants

Biotransformation and persistent metabolites of organohalogen contaminants in model marine and aquatic wildlife and populations